• Title/Summary/Keyword: exclusion criteria

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A Study on the Application of Phased Array Ultrasonic Testing to Main Steam Line in Nuclear Power Plants (원전 주증기배관 웰더렛 용접부 위상배열초음파검사 적용연구)

  • Lee, Seung-Pyo;Kim, Jin-Hoi
    • Transactions of the Korean Society of Pressure Vessels and Piping
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    • v.7 no.3
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    • pp.40-47
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    • 2011
  • KSNPs(Korea Standard Nuclear Power Plant) have been applied the break exclusion criteria to the high energy lines passing through containment penetration area to ensure that piping failures would not cause the loss of containment isolation function, and to reduce the resulting dynamic effects. Systems with the criteria are the Main Steam system, Feed Water system, Steam Generator Blowdown system, and Chemical & Volume Control system. In accordance with FSAR(Final Safety Analysis Report), a 100% volumetric examination by augmented in-service inspection of all pipe welds appled the break exclusion criteria is required for the break exclusion application piping. However, it is difficult to fully satisfy the requirements of inspection because 12", 8" and 6" weldolet weldments of Main Steam pipe line have complex structural shapes. To resolve the difficulty on the application of conventional UT(Ultrasonic Testing) technique, realistic mock-ups and UT calibration blocks were made. Simulations of conventional UT were performed utilizing CIVA, a commercial NDE(Nondestructive Examination) simulation software. Phased array UT experiments were performed through mock-up including artificial notch type flaws. A phased array UT technique is finally developed to improve the reliability of ultrasonic test at main steam line pipe to 12", 8" and 6" branch connection weld.

Home Care Nursing: An Economic Analysis (가정간호의 경제성 평가에 관한 문헌분석)

  • Lim, Ji Young;Kim, Ji Young
    • Journal of Korean Academic Society of Home Health Care Nursing
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    • v.20 no.2
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    • pp.141-151
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    • 2013
  • Purpose: The purpose of this study was to examine the economic effectiveness of by conducting a literature review of published articles, masters theses, and doctoral dissertations. Method: Prior to the literature review, inclusion-exclusion criteria were established. We then reviewed 1,029 CINAHL, MEDLINE, and Cochrane DB papers, and 153 RISS papers collected between Results: A total of 12 studies met the inclusion-exclusion criteria.-effectiveness: 6 cost-effectiveness studies, 1 cost-utility studies, and 5 cost-benefit studies. Each of the 12 reviewed studies concluded that home care nursing had greater economic benefits than other compared healthcare services. Conclusion: Home care nursing has significant economic benefits in multi health care service settings and for various patient groups. Therefore these results will be used a critical evidence for the development of economically effective home based health care systems for future policy making.

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Diagnosis of Multiple Sclerosis: 2017 McDonald Diagnostic Criteria (다발경화증의 진단: 2017 맥도널드진단기준)

  • Sohn, Eun Hee;Jeong, Seung-Hae
    • Journal of the Korean neurological association
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    • v.36 no.4
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    • pp.273-279
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    • 2018
  • Multiple sclerosis (MS) is a diagnosis of exclusion and the lesions or objective findings should disseminate in space and time to diagnose MS. The diagnostic criteria of MS have continuously evolved overtime. The McDonald criteria were originally proposed in 2001, and the revised 2010 McDonald criteria have been used widely. Scientific advances in the past 7 years since 2010 induced the revised 2017 McDonald criteria. All revisions relied entirely on the available evidences, and not expert opinion. In this review, we will provide an overview of the way to diagnose MS and the 2017 McDonald criteria.

Review of Clinical Acupuncture Research Protocols on Cancer in the USA (미국의 암 관련 침 임상 연구 프로토콜 분석)

  • Dobs, Adrian S;Lee, Sang-Hoon
    • The Journal of Korean Medicine
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    • v.28 no.3 s.71
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    • pp.116-125
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    • 2007
  • Objective : To overview the protocols of clinical acupuncture research on cancer in the USA. Methods : Using 'acupuncture' and 'cancer' as keyword search terms in Clinical Trials. gov, 28 clinical studies were found. Three studies by non-American institutions were excluded and 25 studies were analyzed. Analytic parameters were cancer condition, primary outcome, research institution, study design, and acupuncture intervention. Results : Breast cancer was the most frequent single condition in the searched protocols. Pain and quality of life were the primary outcomes in many studies. Memorial Sloan-Kettering Cancer Centerin New York has performed the largest number of acupuncture cancer studies. The majority of studies were randomized controlled trials with active controls or placebo/sham controls. Total enrollment varied between the range of 10 and 700 subjects and ages of these subjects were at least above 18 years old (except one protocol). Most protocols had strict exclusion criteria for acupuncture needling such as bleeding disorders, infection, heart disorder, and central nervous system disorder. Conclusions : Clinical acupuncture studies for cancer patients have focused on pain, quality of life, and side effects induced by anti-cancer therapies. Re-evaluation and cautions for strict exclusion criteria in foreign countries are required to perform multi-national acupuncture trials.

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Factors Influencing the Quality of Life in Low- Income Elders Living at Home: A Literature Review (저소득 재가 노인의 삶의 질에 영향을 미치는 요인에 대한 문헌 분석)

  • Cho, Chung-Min
    • Journal of Korean Public Health Nursing
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    • v.27 no.2
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    • pp.372-383
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    • 2013
  • Purpose: The purpose of this study was to investigate the current state and trends of factors influencing the quality of life in low- income elders living at home. Methods: To carry out this study we established the patient, intervention, comparison, outcomes (PICO) strategy, reviewed 241 published documents from both national and international electronic databases, and finally selected 9 references based on inclusion and exclusion criteria alone. The quality of selected references was assessed using 15 questions. Two reviewers independently examined titles and abstracts and assessed whether each met the predefined inclusion and exclusion criteria. Results: The following factors were significantly associated with quality of life in low- income elders: (1) demographic factors such as number of children, income, and age; (2) health - related factors such as joint exercise capacity, activities of daily living/instrumental activities of daily living, health perception, health promotion behavior, and depression; and (3) socio environmental factors such as family support, community-based service program, leisure activity, and the number of neighborhoods involved. Conclusion: The results of our study provide a definite basis for the development of a policy strategy to improve the quality of life in elders with low income and we hence strongly recommend that any strategy to improve the quality of life in low-income elders be based on the results of our study.

A Study on the Effect of Perception Improvement through GMO Education: A Case of Kyungnam University Students (GMO 교육을 통한 인식개선 효과 연구: 경남대학교 학생을 대상으로)

  • Eun-Hee Seo
    • Journal of the Korean Society of Industry Convergence
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    • v.27 no.2_2
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    • pp.307-318
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    • 2024
  • This study conducted to examine the effects of a GMO education(n=108 university students). Although the experience of encountering GMO was 84.3%, awareness was moderate or lower for 76.9%, 62% were unaware of GMO labeling, and 44.4% had no previous education on GMO. After the education, GMO positive perceptions, specifically in terms of improving work efficiency(p<0.05), negative perception(p<0.001), and GMO knowledge increased significantly(p<0.05). The need for expanding GMO labeling (p<0.05) and adjust to 0.9%(exclusion criteria) for labeling(p<0.001) increased significantly. Moreover, there was a significant increase in the need and willingness to accept a price increase for the full labeling system(p<0.01), with a significant increase in the willingness to pay up to 20%(p<0.05). The pre-contemplation stage showed a significant decrease(p<0.001). The preparation and behavior and maintenance stage showed a significant increase(p<0.001). Based on these findings, it is suggested that GMO education be implemented to provide accurate information and emphasize the necessity of consumers' right to know and choose through the implementation of the full labeling system of GM foods.

Effect of the Peace-Dam Construction on the Flood Discharge and the Flood Stage of the Hwachun-Dam

  • Jun, Byoung-Ho;Shin, Hyun-Suk;Yoon, Jae-Young
    • Korean Journal of Hydrosciences
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    • v.5
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    • pp.17-31
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    • 1994
  • Because of the Keumkangsan-Dam and the Peace-Dam constructed in recent years, it is expected that the peak flood discharge and the peak flood stage at the Hwachun-Dam site have been changed. In this study, two methods were used to simulate and compare the effects of the upstream dam construction on the change of the discharge and the stage. One is the storage function method widely used for the hydrological routing in the country. The other is the DWOPER(Dynamic Wave Operational Model) package conducted on four different scenarios: (1) before the construction of the Keumkangsan-Dam and the Peace-Dam; (2) the exclusion of the Keumkangsan-Dam watershed (before the construction of the Peace-Dam); (3) the exclusion of the Keumkangsan-Dam watershed (after the construction of the Peace-Dam) ; (4) the exclusion of the Peace-Dam watershed. The results of the four test cases from the two methods show that the peak flood discharge and the peak flood stage at the Hwachun-Dam site are reduced due to the construction of the Peace-Dam. From these findings, it is suggested that the operational criteria for the optimal dam-operation of the Hwachun-Dam need to be modified.

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Comparison of porcine and human acellular dermal matrix outcomes in wound healing: a deep dive into the evidence

  • Saricilar, Erin Cihat;Huang, Sarah
    • Archives of Plastic Surgery
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    • v.48 no.4
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    • pp.433-439
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    • 2021
  • Acellular dermal matrices (ADM) are a novel graft. The goal of this systematic review is to evaluate the evidence behind differences in human and porcine ADM, irrelevant of manufacturing method, and to determine if there is enough of an evidence base to change clinical practice. An extensive literature search was performed through MEDLINE and Embase with search terms defining a population, intervention and outcome. Title and abstract exclusion were performed with other exclusion criteria. In 191 articles were found after exclusion of duplicates, with only 29 remaining following exclusions. Ten studies were found to have level I and II evidence (I=3, II=8), of which two were histopathological, one was an animal model, one was a systematic review, and six were clinical. The remaining studies were reviewed and considered for discussion, but did not hold high enough standards for medical evidence. Strong clinical evidence already exists for the use of human ADM, but questions of access, cost, and ethics require consideration of a xenograft. Histopathologically, evidence suggests minimal long-term differences between human and porcine ADM, although there is a short acute immune response with porcine ADM. Clinically, there is limited difference in outcomes, with a small range in effect of different ADM preparations. Considering the effectiveness of ADM in wound healing, more high-level research with appropriate statistical analysis to facilitate a future meta-analysis is recommended to justify a transition from human to porcine ADM.

Analysis of Recent Clinical Studies to Establish Korean Herbal Medicine Clinical Trial Guidelines for the Common Cold (감기 임상시험 가이드라인 제정을 위한 최신 임상시험 연구 분석)

  • Kim, Kwan-il;Lee, Ho-jung;Lee, Beom-joon;Jung, Hee-jae;Jung, Sung-ki;Lee, Jun-hee
    • The Journal of Internal Korean Medicine
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    • v.37 no.1
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    • pp.109-134
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    • 2016
  • Objectives: The aim of this study was to help develop a guideline for the common cold. We searched recent clinical studies of the common cold in Western medicine and reviewed their objectives, inclusion and exclusion criteria, primary outcome, secondary outcome, and assessment tools to establish evidenced-based guideline.Methods: We searched electronic databases (Cochrane Library, MEDLINE, EMBASE) to identify eligible randomized controlled trials (RCTs) about the common cold for the last 10 years. We included 29 RCTs and showed their research summary via their objectives, participants, interventions, control, treatment duration, and results. We also analyzed the definition of the common cold presented in the article, inclusion and exclusion criteria, primary and secondary outcomes, and assessment tools.Results: We reported the aforementioned areas in detail. At first, the definition of the common cold was confused across the articles. Second, herbal medication clinical trials for the common cold have been extensively studied recently. Third, the eligibility criteria frequently included the Jackson Symptom score. Fourth, validated assessment tools (i.e., the Wisconsin Upper Respiratory Symptom Survey-21) have only been used in a few recent studies.Conclusions: Our research will be helpful to establish Korean herbal medicine clinical trial guidelines for the common cold.

Standardizing the evaluation criteria on treatment outcomes of mandibular implant overdentures: a systematic review

  • Kim, Ha-Young;Shin, Sang-Wan;Lee, Jeong-Yol
    • The Journal of Advanced Prosthodontics
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    • v.6 no.5
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    • pp.325-332
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    • 2014
  • PURPOSE. The aim of this review was to analyze the evaluation criteria on mandibular implant overdentures through a systematic review and suggest standardized evaluation criteria. MATERIALS AND METHODS. A systematic literature search was conducted by PubMed search strategy and hand-searching of relevant journals from included studies considering inclusion and exclusion criteria. Randomized clinical trials (RCT) and clinical trial studies comparing attachment systems on mandibular implant overdentures until December, 2011 were selected. Twenty nine studies were finally selected and the data about evaluation methods were collected. RESULTS. Evaluation criteria could be classified into 4 groups (implant survival, peri-implant tissue evaluation, prosthetic evaluation, and patient satisfaction). Among 29 studies, 21 studies presented implant survival rate, while any studies reporting implant failure did not present cumulative implant survival rate. Seventeen studies evaluating peri-implant tissue status presented following items as evaluation criteria; marginal bone level (14), plaque Index (13), probing depth (8), bleeding index (8), attachment gingiva level (8), gingival index (6), amount of keratinized gingiva (1). Eighteen studies evaluating prosthetic maintenance and complication also presented following items as evaluation criteria; loose matrix (17), female detachment (15), denture fracture (15), denture relining (14), abutment fracture (14), abutment screw loosening (11), and occlusal adjustment (9). Atypical questionnaire (9), Visual analog scales (VAS) (4), and Oral Health Impact Profile (OHIP) (1) were used as the format of criteria to evaluate patients satisfaction in 14 studies. CONCLUSION. For evaluation of implant overdenture, it is necessary to include cumulative survival rate for implant evaluation. It is suggested that peri-implant tissue evaluation criteria include marginal bone level, plaque index, bleeding index, probing depth, and attached gingiva level. It is also suggested that prosthetic evaluation criteria include loose matrix, female detachment, denture fracture, denture relining, abutment fracture, abutment screw loosening, and occlusal adjustment. Finally standardized criteria like OHIP-EDENT or VAS are required for patient satisfaction.