• Bulletin of the Korean Chemical Society
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• 제13권3호
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• pp.325-331
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• 1992

By using the general theoretical framework proposed recently for treating the fluorescence quenching kinetics, we investigate the effect of light pulse intensity on the decay of fluorescence which follows excitation of fluorophors by the light pulse of very short but finite duration. It is seen that conventional theory breaks down when the exciting light pulse has a pulse width comparable to the fluorescent lifetime and its intensity is very high. We also find that even when the light intensity is not too high, conventional theory may fail in either of the following cases: (i) when the quencher concentration is high, (ii) when there is an attractive potential of mean force between the fluorophor and quencher, or (iii) when the energy transfer from the fluorophor to the quencher may also occur at a distance, e.g., via dipole-dipole interaction. The validity of the predictions of the present theory may thus be tested by fluorescence quenching experiments performed under such situations.

• 한국해양공학회지
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• 제35권3호
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• pp.216-228
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• 2021

In the present study, the performance of a floating oscillating water column (OWC) device has been studied in regular waves. The OWC model has the shape of a hollow cylinder. The linear potential theory is assumed, and a matched eigenfunction expansion method(MEEM) is applied for solving the diffraction and radiation problems. The radiation problem involves the radiation of waves by the heaving motion of a floating OWC device and the oscillating pressure in the air chamber. The characteristics of the exciting forces, hydrodynamic forces, flow rate, air pressure in the chamber, and heave motion response are investigated with various system parameters, such as the inner radius, draft of an OWC, and turbine constant. The efficiency of a floating OWC device is estimated in connection with the extracted wave power and capture width. Specifically, the piston-mode resonance in an internal fluid region plays an important role in the performance of a floating OWC device, along with the heave motion resonance. The developed prediction tool will help determine the various design parameters affecting the performance of a floating OWC device in waves.

• 한국해안해양공학회지
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• 제17권3호
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• pp.138-148
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• 2005

부유체 및 부유식 교량과 같은 부유식 구조물이 파랑하중에 대하여 나타내는 동적거동을 주파수영역에서 구하는 연구를 수행하였다. 먼저, 부분적으로 유체에 잠겨 파랑하중의 작용을 받는 부유체에 대하여, 이의 강체운동과 관련된 동유체력계수인 부가질량, 감쇠 및 파강제력를 선형포텐셜이론과 경계요소법을 이용하여 주파수 영역에서 산정한다 다음으로,부유식 교량과 같이 앞에서 구한 부유체로 지지되며 유한요소를 이용하여 모델링 되는 부유식 구조물에 대하여, o)의 동적거동에 관한 운동방정식을 수립한다. 동유체력계수들이 주파수 의존적 성질을 가지므로 해석은 주파수영역에서 수행한다. 적용 예제로서 반구와 같은 부유체를 이용하여 해석결과를 문헌과 비교 검증한 후,부유식 교량을 지지하는 폰툰형 부유체에 대한 동유체력계수들을 구하고, 이를 이용하여 설계 파랑하중을 받는 부유식 교량의 동적 거동해석을 수행한다. 해석 예제를 주파수영역에서 해석한 결과 입사파스펙트림의 피크 주파수와 교량의 고유진동수가 가까워 응답이 증폭될 소지가 있었으나 주파수 의존적인 파강제력의 피크가 벗어난 영향으로 응답이 증폭되지 않음을 알 수 있다.

• 한국진공학회:학술대회논문집
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• 한국진공학회 2009년도 제38회 동계학술대회 초록집
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• pp.13-13
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• 2010

Switching an elementary excitation by injecting a single carrier would offer the exciting opportunity for the ultra-high data storage technologies. However, there has been no methodology available to investigate the interaction of low energy discrete carriers with nano-structures. In order to map out the spatial dependency of such single carrier level interactions, we developed a pulse-and-probe algorithm, combining with low temperature scanning tunneling microscopy. The new tool, which we call single carrier spectroscopy, allows us to track the interaction with the target macrostructure with tunneling carriers on a single carrier basis. Using this tool, we demonstrate that it is possible not only to locally write and erase individual bi-solitons, reliably and reversibly, but also to track of creation yields of single and multiple bi-solitons. Bi-solitons are pairs of solitons that are elementary out-of-phase excitations on anti-ferromagnetically ordered pseudo-spin system of Si dimers on Si(001)-c(42) surfaces. We found that at low energy tunneling the single bisoliton creation mechanism is not correlated with the number of carriers tunneling, but with the production of a potential hole under the tip. An electric field at the surface determines the density of the local charge density under the tip, and band-bending. However a rapid, dynamic change of a field produces a potential hole that can be filled by energetic carriers, and the amount of energy released during filling process is responsible for the creation of bi-solitons. Our model based on the field-induced local hole gives excellent explanation for bi-soliton yield behaviors. Scanning tunneling spectroscopy data supports the existence of such a potential hole. The mechanism also explains the site-dependency of bi-soliton yields, which is highest at the trough, not on the dimer rows. Our study demonstrates that we can manipulate not just single atoms and molecules, but also single pseudo-spin excitations as well.

• 한국해양공학회지
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• 제31권3호
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• pp.208-218
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• 2017

The performance of a wave energy converter (WEC) that uses the rolling motion of a partially submerged pendulum plate in front of a quay wall was analyzed. The wave exciting moment and hydrodynamic moment were obtained using a matched eigenfunction expansion method (MEEM) based on the linear potential theory, and then the roll motion response of a pendulum plate, time averaged extracted power, and efficiency were investigated. The optimal PTO damping coefficient was suggested to give the optimal extracted power. The peak value of the optimal extracted power occurs at the resonant frequency. The resonant peak and its width increase as the submergence depth of the pendulum plate decreases and thickness of the pendulum plate increases. An increase in the wave incidence angle reduces the efficiency of the wave energy converter. In addition, the WEC using a rolling pendulum plate contributes not only to the extraction of the wave energy, but also to a reduction in the waves reflected from the quay wall, which helps to stabilize ships going near the quay wall.

• BMB Reports
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• 제43권7호
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• pp.451-460
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• 2010

Starting with the first publication of lacZ gene fusion in 1980, reporter genes have just entered their fourth decade. Initial studies relied on the simple fusion of a promoter or gene with a particular reporter gene of interest. Such constructs were then used to determine the promoter activity under specific conditions or within a given cell or organ. Although this protocol was, and still is, very effective, current research shows a paradigm shift has occurred in the use of reporter systems. With the advent of innovative cloning and synthetic biology techniques and microfluidic/nanodroplet systems, reporter genes and their proteins are now finding themselves used in increasingly intricate and novel applications. For example, researchers have used fluorescent proteins to study biofilm formation and discovered that microchannels develop within the biofilm. Furthermore, there has recently been a "fusion" of art and science; through the construction of genetic circuits and regulatory systems, researchers are using bacteria to "paint" pictures based upon external stimuli. As such, this review will discuss the past and current trends in reporter gene applications as well as some exciting potential applications and models that are being developed based upon these remarkable proteins.

• 대한조선학회논문집
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• 제40권4호
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• pp.16-21
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• 2003

The very large container ships have been built recently and those ships have very small structural rigidity compared with the other conventional ships. As a result, the destruction of ship hull is occurred by the springing including to warping phenomena due to encounter waves. In this study, the solutions of hydrodynamic coefficients are obtained by solving the three dimensional source distribution method and the forward speed Green function representing a translating and pulsating source potential for infinite water depth is used to calculating the integral equation. The vessel is longitudinally divided into various sections and the added mass, wave damping and wave exciting forces of each section is calculated by integrating the dynamic pressures over the mean wetted section surface. The equations for six degree freedom of motions is obtained for each section in the frequency domain and stiffness matrix is calculated by Euler beam theory. The computations are carried out for very large ship and effects of bending and torsional ridigity on the wave frequency and angle are investigated.

• 대한토목학회논문집
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• 제14권3호
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• pp.473-485
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• 1994

정말진동환경을 요구하는 혐진기기 하부의 콘크리트슬래브를 대상으로 하여 시간영역에서만이 아니라 진동수영역에서의 진동수준을 허용진동범위 이하로 제어하므로써 요구되는 진동환경을 조성하는데 본 연구의 목적이 있다. 이를 위하여 콘크리트슬래브에 대한 진동실험을 실시하여 진동수영역에서의 동적응답 및 가진점과 응답점간의 진동수응답함수를 구한다. 또한 실험적모드해석법에 의하여 콘크리트슬래브의 동특성을 분석한다. 이를 근거로 외부로부터의 가진진동수와 콘크리트슬래브의 고유진동수간의 공진현상을 피하기 위하여 계의 동특성을 변경하므로써 구조물의 동적응답을 제어할 수 있다.

• 한국정밀공학회:학술대회논문집
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• 한국정밀공학회 1997년도 추계학술대회 논문집
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• pp.969-972
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• 1997

Ultrasonic machining technology has been developed over recent years for he manufacture of cost-effective and quality-assured precision parts for several industrial application such as optics, semiconductors, aerospace, and automobile application. The past decade has seen a tremendous in the use of ceramic in structural application. The excellent thermal, chemical and wear resistance of these material can be realized because of recent improvement in the overall strength and uniformity of advanced ceramics. Ultrasonic machining, in which abrasive particles in slurry with water are presented to the work surface in the presence of an ultrasonic-vibrating tool, is process which should be of considerable interest, as its potential is not limited by he electrical or chemical characteristics of the work material, making it suitable for application to ceramics. In order to improve the currently used ultrasonic machining using ultrasonic energy, technical accumulation is needed steadily through development of exciting device of ultrasonic machine composed of piezoelectric vibrator and horn. This paper intends to further the understanding of the basic mechanism of ultrasonic machining for brittle material and ultrasonic machining of ceramics based in the fracture-mechanic concept has been analyzed.

• 대한핵의학회지
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• 제38권2호
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• pp.171-174
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• 2004

Angiogenesis, the formation of new capillaries from existing vessels, increases oxygenation and nutrient supply to ischemic tissue and allows tumor growth and metastasis. As such, angiogenesis targeting provides a novel approach for cancer treatment with easier drug delivery and less drug resistance. Therapeutic anti-angiogenesis has shown impressive effects in animal tumor models and are now entering clinical trials. However, the successful clinical introduction of this new therapeutic approach requires diagnostic tools that can reliably measure angiogenesis in a noninvasive and repetitive manner. Molecular imaging is emerging as an exciting new discipline that deals with imaging of disease on a cellular or genetic level. Angiogenesis imaging is an important area for molecular imaging research, and the use of radiotracers offers a particularly promising technique for its development. While current perfusion and metabolism radiotracers can provide useful information related to tissue vascularity, recent endeavors are focused on the development of novel radioprobes that specifically and directly target angiogenic vessels. Presently available proges include RGD sequence containing peptides that target ${\alpha}_v\;{\beta}_3$ integrin, endothelial growth factors such as VEGF or FGF, metalloptoteinase inhibitors, and specific antiangiogenic drugs. It is now clear that nuclear medicine techniques have a remarkable potential for angiogenesis imaging, and efforts are currently continuing to develop new radioprobes with superior imaging properties. With future identification of novel targets, design of better probes, and improvements in instrumentation, radiotracer angiogenesis imaging promises to play an increasingly important role in the diagnostic evaluation and treatment of cancer and other angiogenesis related diseases.