• Title/Summary/Keyword: exciting potential

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Theoretical Study on the Dynamic Response of a Moored Buoy with Minimum Vertical Wave-exciting Force in Irregular Waves (수직운동(垂直運動)이 최소(最小)인 부표(浮標)의 불규칙파(不規則波)중 계류상태(繫留狀態)에 대한 동력학적(動力學的) 해석(解析))

  • H.S.,Choi;Hyo-Chul,Kim;Woo-Jae,Seong
    • Bulletin of the Society of Naval Architects of Korea
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    • v.21 no.3
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    • pp.43-50
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    • 1984
  • A body form, which experiences minimum vertical wave-exciting forces in the vicinity of a prescribed wave frequency in water of finite depth, is obtained by an approximate method. Its configuration has the symmetry with respect to the vertical axis, expressed in terms of exponential functions. By distributing three-dimensional pulsating sources and dipoles on the immersed surface of the body, a velocity potential is determined and subsequently hydrodynamic forces including the 2nd-order time-mean drift forces are calculated. The dynamic behavior of the body moored in irregular waves is investigated numerically by using central difference method. Hereby irregular wave trains are simulated with examining its repeatability by comparing the resulting spectrum with original one. Numerical results indicated that the body form obtained from the present analysis possesses in general a favorable hydrodynamic characteristics in comparison with a spherical buoy and that the maximum excursion of the body can be significantly reduced by setting pre-tension of an appropriate amount in the mooring cable.

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PSMA Inhibitors for Nuclear Imaging and Radiotherapy of Prostate Cancer

  • Sajid Mushtaq;Tugsuu Uyanga;Park Ji Ae;Jung Young Kim
    • Journal of Radiopharmaceuticals and Molecular Probes
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    • v.9 no.1
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    • pp.23-33
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    • 2023
  • Prostate cancer ranks as the world's second most frequently diagnosed cancer among men, and is responsible for the fifth highest number of cancer-related deaths in this population. The development of effective diagnostic and therapeutic approaches for prostate cancer remains a major challenge in the field of oncology. Over the past few years, the prostate-specific membrane antigen (PSMA) has raised as a hopeful tracer for the diagnosis and treatment of prostate cancer.Various radioisotopes, such as 131I, 99mTc, 68Ga, and 177Lu, have been used to label PSMA analogues, with varying degrees of success. Among these, 68Ga-PSMA-11 and 177Lu-PSMA-617 have emerged as the most promising radioligands for clinical use. Recently, researchers have been exploring the use of other radioisotopes, such as 211At, 89Zr, 64/67Cu, and 203/212Pb, for the labeling of PSMA-targeted radioligands. These radioisotopes have unique properties that may offer advantages over existing radioligands, such as longer half-lives, higher specific activities, and different emission profiles. Efforts are currently underway to develop these radiopharmaceuticals and make them more widely available for clinical use. These exciting developments highlight the potential of PSMA-targeted radioligands for the diagnosis and treatment of prostate cancer, and provided significant implications for the management of this disease in the future. The current study aims to provide a comprehensive summary of the latest research and clinical applications of radiolabeled PSMA inhibitors for diagnoses and therapy of prostate cancer, emphasizing the exciting developments in the field and their potential impact on clinical practice.

A Stuty on the Dynamic Response of an Axisymmetric Buoy in Regular Waves (축대칭 부표의 규칙파중 운동특성에 대한 연구)

  • Key-Y.,Hong;Hyo-Chul,Kim;Hang-S.,Choi
    • Bulletin of the Society of Naval Architects of Korea
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    • v.23 no.3
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    • pp.1-9
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    • 1986
  • Herein the dynamic response of an axisymmetric buoy to regular wave is studied within linear potential theory. The buoy has a particular geometry so that it should experience minimum wave-exiting force on the vertical direction at a precribed wave number in water of finite depth. Invoking the Green's theorem a velocity potential is generated by distributing pulsating sources and doublets on the immersed surface of the buoy at its mean position. Hydrodynamic forces and moments are obtained approximately by summation of the products of linear pressure and directional mesh area over the immersed surface. Model tests are carried out to measure the wave-exciting forces, hydrodynamic forces and motion responses. The experimental results in general agree fairly well with the numerical ones. From the analytical and experimental works it is found that the pitching motion and its coupling effect affect significantly the motion characteristics of the freely-floating axisymmetric buoy in regular waves.

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A Study on the Propogation Velocity of Biological Action Potential (생체의 자극 전도속도에 관한 연구)

  • Che, Gyu-Shik;Kwon, Yong-Chan
    • Journal of Advanced Navigation Technology
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    • v.14 no.6
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    • pp.1002-1009
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    • 2010
  • I made the axon to the electrical transmission model and then constructed electrical equivalent model using Kirhhoff's current law and voltage law in this paper. I calculated various axon parameters in order to analyze the electrical potential hehavior versus minute distance chang of axon. The transmission velocity of unmyelinated nerve is proportional to square root of axon diameter, while that of myelinated nerve is directly proportional to its diameter. Because the transmission of myelin sheath is independent of voltage unlike unmyelinated sheath, the Hodgkin-Huxley model across the membrane is not so precise.

Numerical Simulation of Wave Forces acting on Fixed Offshore Structures Using Hybrid Scheme (하이브리드 기법을 이용한 고정된 해양구조물에 작용하는 파랑하중에 관한 수치 시뮬레이션)

  • Nam, Bo-Woo;Hong, Sa-Young;Kim, Yong-Hwan
    • Journal of Ocean Engineering and Technology
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    • v.24 no.6
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    • pp.16-22
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    • 2010
  • In this paper, the diffraction problems for fixed offshore structures are solved using a hybrid scheme. In this hybrid scheme, potential-based solutions and the Navier-Stokes-based finite volume method (FVM) with a volume-of-fluid (VOF) method are combined. We introduce a buffer zone for efficient wave-making and damping. In this buffer zone, the near field solution from FVM-VOF is gradually changed to Stokes' 2nd order wave solutions. Three different models, including the truncated cylinder, sphere, and wigleyIII model, are numerically investigated in regular waves with a wave steepness of 1/30. The efficiency and accuracy of the hybrid scheme are numerically validated from results using different domain sizes and buffer zones. The wave exciting forces from the FVM-VOF simulations are compared with experiments and potential-based solutions from the higher-order boundary element method (HOBEM). This comparison shows good agreement between the hybrid scheme and potential-based solutions.

A Study on the Bio-response to the Underthreshold Stimulation (임계치 이하의 자극에 대한 생체의 반응 연구)

  • Che, Gyu-Shik
    • Journal of Advanced Navigation Technology
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    • v.14 no.3
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    • pp.439-445
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    • 2010
  • The signal transmission of human body is processed by the action potential from each cell unit. This kind of action potential is taken place and transmitted by the ions through cell membrane, and ultimately explained as an electrical signal concept. The fact that the information is established as an electrical status as well as various senses from the bio-organozm has been addressed through several studies. By the way, this nervous transmission relation has been described and analyzed qualitatively in the mean time. I established new algorithm to analyze these relations quantitatively and implemented them using existing bio-data in this paper. The study, however, was limited to underthreshold potential to excite the nervous system against the outer stimulation. This is very much analog to electrical transient of the switching circuit, and therefore, I analyzed it based on this analog. I made it clear that the results derived here is the basis further study topic.

A Study on Gamers Segmentation based upon Uses and Gratifications of Mobile games (모바일게임 이용 충족이론을 기반으로 한 모바일 게이머 유형 분석에 관한 연구)

  • Han, Kwang-Hyun;Kim, Tae-Ung
    • Proceedings of the Korean Operations and Management Science Society Conference
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    • 2005.10a
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    • pp.133-164
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    • 2005
  • Mobile games have emerged as the most innovative entertainment technology, adding new revenue streams, taking advantage of the potential of wireless applications and service offerings. Mobile games, like any other types of computer game, offer a unique value for users in providing an exciting digital experience in virtual worlds. Players can become empowered through the development of new characters and strategies within games to achieve rewarding successes against the computers and other players. The overall trend for mobile games is towards bigger, more colorful, more involving and exciting contents, which will build upon the developing capabilities of mobile phones and networks in order to bring new styles, concepts and experiences of game play to the users. In this paper, we attempt to investigate the demographic factors which play critical roles in determining the level of playing times; classify mobile gamers based on their motives for playing games; and empirically test differences in their demographic factors and mobile game usage. Statistical results show that significant differences in playing times exist, depending upon their age, gender, mobile device, mobile phone usage, mobile game experiences, and preferred games genres. Applying Factor analysis, we have identified Escape, Social interaction, Challenge and Competition, Fantasy, Diversion and Relaxation, Ease of Accessibility as key motivators for playing mobile games. Additional cluster analysis shows that the categorization of gamers, according to their usage habits and the key motivators for playing, can be made as follows: M-gamers, Multi-gamers and Communication-focused gamers. Further correlation of these grouping with socio-economic data shows the significant differences in gaming habits and patterns of mobile phone use.

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Wave Force Analysis of the Three Vertical Cylinders in Water Waves

  • Kim, Nam-Hyeong;Cao, Tan Ngoc Than
    • Journal of Navigation and Port Research
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    • v.32 no.7
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    • pp.543-552
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    • 2008
  • The diffraction of waves by three bottom fixed vertical circular cylinders is investigated by using the boundary element method. This method has been successfully applied to the isolated vertical circular cylinder and now is used to study the interaction between waves and multiple vertical cylinders. In this paper, a numerical analysis by the boundary element method is developed by the linear potential theory. The numerical analysis by the boundary element method is based on Green's second theorem and introduced to an integral equation for the fluid velocity potential around the vertical circular cylinders. To verify this method, the results obtained in present study are compared with the results computed by the multiple scattering method. The results of the comparisons show strong agreement. Also in this paper, several numerical examples are given to illustrate the effects of various parameters on the wave exciting force such are the separation distance, the wave number and the incident wave angle. This numerical computation method might be used broadly for the design of various offshore structures to be constructed in the future.

Biological Control Strategy of Uzi Fly in Sericulture

  • Singh, R.N.;Saratchandra, Beera
    • International Journal of Industrial Entomology and Biomaterials
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    • v.6 no.2
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    • pp.125-132
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    • 2003
  • Uzi fly (Exorista bombycis Louis) is one of the major larval endo-parasitoid of silkworm (Bombyx mori). It causes extensive damage to sericulture industry. The application of synthetic organic pesticides has tremendous impact on minimizing pest population but their overuse and frequent misuse and high sensitivity towards the silkworms, has forced the entomologists to search for alternatives to chemical control, which is safe to silkworm, environment and farm workers. Biological control continues to offer exciting possibilities for the control of fly pest population. It is environmentally safe alternative to chemical control and offering a long-term protection. Several potential hymenopteran parasitoids have been screened. Among successful natural enemies, Nesolynx thymus, Trichomalopsis apanteloctena, Trichopria sp., Brachymeria lasus, Pediobius sp., Spalangia sp., Spilomicrus karnatakensis and Dhirhinus sp. are important. It is essential to predict accurately the efficacy of these natural enemies in a new habitat prior to its introduction. The important desirable attributes of these potential parasitoids viz., host searching capacity, specificity, power of increase and fitness and adaptability of the parasitoid in new environment has been recorded. Results of the host parasitoid interaction indicate that the aging of the host function as a factor that influence the host finding efficiency of the parasitoid. It is highly scored with 15-20 hrs old pupa of the host. However, aging of the parasitoid does not significantly affect it. The sex ratio is female biased which is advantageous from biological control point of view, Biological suppression methods involving conservation and utilization of natural enemies have been discussed in detail.

Analysis of density diffusion analysis by Fick's laws in the human body (픽법에 의한 생체 내의 농도 확산 분석)

  • Che, Gyu-Shik
    • Journal of Advanced Navigation Technology
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    • v.16 no.4
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    • pp.657-664
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    • 2012
  • One of the methods to transmit solute through solvent is diffusion. Various particles or molecules including several charged ions in the body diffuse from high density region to low density due to density difference or external electric field. This kind of mechanism is due to thermal motion of each solute molecules. These situations can be deployed using Fick's first and second laws that govern diffusion phenomena in the body. I analysis these diffusion status of material in the body using above mentioned Fick's laws and then implement them through illustration.