• BMB Reports
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• 제38권3호
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• pp.350-353
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• 2005

Alanine at residue 73 (Ala-73) and aspartate at residue 9 (Asp-9) are characteristic to both Cw6 and Cw7 alleles of HLA-C gene and have been suggested as possible markers for psoriasis vulgaris (PsV). However, the results from various ethnic groups/populations are contradictory and inconclusive. In this study, an attempt has been made to examine the association between HLA-C (Ala-73 and Asp-9) and susceptibility to PsV among Saudi patients. Genomic DNA was extracted from 25 Saudi PsV patients and 75 control subjects. Polymerase chain reaction (PCR) was performed to amplify HLA-C sequences using earlier reported primers, C133P and C243PR. Sequence-specific primers were used to specifically detect nucleotide coding for Ala-73 and Asp-9 in all the subjects. The results showed significantly higher frequency of Asp-9 (84.0% versus 61.3%) in PsV patients as compared to controls (p < 0.05, 2-tailed Fisher's exact test). The frequencies of Ala-73 among PsV patients (92%) and controls (88%) did not differ significantly.

• Journal of Welding and Joining
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• 제16권3호
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• pp.129-140
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• 1998

An interface system was developed to offer the welding capability to a robot controller which had not any embedded function for arc welding before, and also an arc sensor algorithm was proposed for weld seam tracking of the welding robot. For the interface system between the robot controller and welding equipments, data communication software and interface connections were composed. The interface system was mae to correspond welding condition, correction data, operation sequence and current status with the robot controller by mutual had shaking and digital signal transfer. Graphic user interface program developed under the environment of windows made it easy to monitor data communication and operation status, and to control welding and sensing sequence. Arc sensing algorithm proposed in this study to compensate torch position error was based on a fuzzy logic with the variables of current difference and current differenced change at torch weaving extremities. The developed interface system could be successfully implemented in between welding equipments and the robot controller, and showed normal status and exact function in data and signal communication between the systems. The whole robot welding system was then examined to verify its welding and seam tracking capabilities in horizontal fillet, vertical fillet, and 3-dimensional fillet weldment. The experiments revealed sound weld bead shapes and also good seam tracing results.

• 식물병연구
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• 제29권2호
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• pp.130-136
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• 2023

Citrus melanoses caused by Diaporthe citri, has been one of the serious diseases in many citrus orchards of Jeju Island. To protect melanose in citrus farms, a fast and exact diagnosis method is necessary. In this study, diseased leaves and dieback twigs were collected from a total of 49 farms within March to April in 2022. A total of 465 fungal isolates were obtained from a total of 358 isolated plant samples. Among these fungal isolates, 40 representatives of D. citri isolates which were isolated from 22 twigs and 18 leaves on 23 farms were found based on cultural characteristics on potato dextrose agar and conidial morphology. Additionally, the molecular assay was carried out and compared with those by morphological diagnosis. All isolates were identified as D. citri by analyzing the sequences at the internal transcribed spacer (ITS) rDNA region using primers of ITS1/ITS4 or at β-tubulin using primer Btdcitri-F/R. Therefore, based on the present study, where the results of morphological identification of conidial type were consistent with DNA sequence analysis of certain gene, choosing a suitable method for a fast diagnosis of citrus melanose was suggested.

• 응용통계연구
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• 제6권1호
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• pp.125-143
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• 1993

관측치가 (0, T]의 구간에서 균일하게 분포한다는 가설에 대하여, 관측치의 집락화를 검정하는 과정에서 스캔 통계량을 사용할 수 있다. 본 논문에서는 스캔 통계량의 확률분포의 근사분포가 어떠한 이론적 배경으로 개선되어 왔는 지를 고찰하고, 실제로 응용된 예를 살펴보기로 한다. 광물 매장을 조사하기 위한 항공탐사, 두 개의 아미노산 염기서열(amino-acid sequence)을 비교하는 과정에서 스캔 통계량은 사용되어 왔다. 지놈(genome)의 連鎖(sequence)에서 돌연변이가 발생한 위치에 대하여 집락의 가능성을 검색하는 방법으로 스캔 통계량을 이용할 수 있음을 보이고, 이에 대한 구체적인 문제 구성은 추후 연구과제로 제시한다.

• 한국정보과학회논문지:데이타베이스
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• 제30권2호
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• pp.168-175
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• 2003

지금까지 문자열 데이타에 대한 선택도 추정은 문자열들의 등장 회수에 대한 정보를 저장하고 있는 '카운트 서픽스 트리'를 생성한 뒤, 이 트리를 이용하여 부분 문자열들의 선택도를 추정하는 방법으로 이루어졌다. 그런데, 문자열 데이타가 생물학 서열처럼 매우 길어질 경우 카운트 서픽스 트리를 생성하는 일은 거의 불가능해진다는 문제점이 발생한다. 이 논문에서는 길이가 q인 부분 문자열들만을 삽입한 '카운트 큐그램 트리'를 제안한다. 카운트 큐그램 트리는 서열 내의 길이가 q 이하인 모든 부분 문자열(큐그램) 들의 정확한 등장 회수를 저장하고 있으며, 문자열의 전체 길이 N에 상관없는 크기로, O(N) 시간에 생성 가능하다. 또한, 이 논문에서는 카운트 큐그램 트리를 이용한 'k번째 최대겹침' 추정 방법을 제시한다. 이 추정 방법은 질의 문자열을 길이 q인 부분 문자열로 나눌 때 부분 문자열들의 겹치는 정도 k를 선택할 수 있도록 한 방법으로 이전 연구에서 제시한 '최대겹침' 방법을 확장하였다. q와 k를 변화시키며 진행한 실험 올 통해 대부분의 경우에 매우 정확하게 선택도를 추정할 수 있음을 확인하였다.

• Nuclear Engineering and Technology
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• 제49권4호
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• pp.710-720
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• 2017

In Korea, many nuclear power plants operate at a single site based on geographical characteristics, but the population density near the sites is higher than that in other countries. Thus, multiunit accidents are a more important consideration than in other countries and should be addressed appropriately. Currently, there are many issues related to a multiunit probabilistic safety assessment (PSA). One of them is the quantification of a multiunit PSA model. A traditional PSA uses a Boolean manipulation of the fault tree in terms of the minimal cut set. However, such methods have some limitations when rare event approximations cannot be used effectively or a very small truncation limit should be applied to identify accident sequence combinations for a multiunit site. In particular, it is well known that seismic risk in terms of core damage frequency can be overestimated because there are many events that have a high failure probability. In this study, we propose a quantification method based on a Monte Carlo approach for a multiunit PSA model. This method can consider all possible accident sequence combinations in a multiunit site and calculate a more exact value for events that have a high failure probability. An example model for six identical units at a site was also developed and quantified to confirm the applicability of the proposed method.

• Journal of applied mathematics & informatics
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• 제25권1_2호
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• pp.455-470
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• 2007

In phylogenetic tree construction the neighbor-joining algorithm is the most well known method which constructs a trivalent tree from a pairwise distance data measured by DNA sequences. The core part of the algorithm is its cherry picking criterion based on the tree structure of each quartet. We give a generalized version of the criterion based on the exact box model of quartets, known as the tight span of a metric. We also show by experiment why neighbor-joining and the quartet consistency count method give similar performance.

• 한국전산구조공학회:학술대회논문집
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• 한국전산구조공학회 2004년도 봄 학술발표회 논문집
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• pp.317-324
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• 2004

Shape design optimization of shell structure is implemented on a basis of integrated framework of geometric modeling and finite element analysis which is constructed on the geometrically exact shell theory. This shell theory enables more accurate and robust analysis for complicated shell structures, and it fits for the nature of B-spline function which Is popular modeling scheme in CAD field. Shape of laminated composite shells is optimized through genetic algorithm and sequential linear programming, because there ire numerous optima for various configurations, constraints, and searching paths. Sequential adaptation of global and local optimization makes the process more efficient. Two different optimized results of laminated composite shell structures to minimize strain energy are shown for different layup sequence.

• 한국정보통신학회논문지
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• 제2권4호
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• pp.553-558
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• 1998

We present in this paper the ture union bound of the performance of chip level detection for coded DS/CDMA system operating in Rician fading channels such as LEO satellite mobile radio where the maximum doppler frequency is very high. The main objective of this paper is to calculate the exact doe union bound of BER performance of different performance of different quadrature detectors and to find a optimum spreading factor as a function of fade rate. The rationale of using multiple chip detection is to reduce the effective fade rate or variation. We considered chip level differential detection, chip level maximum likelihood sequence estimation, noncoherent detection and coherent detection with perfect channel state information as a reference.

• 대한수학회보
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• 제54권6호
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• pp.2043-2051
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• 2017

Consider a sequence of compactly supported Hamiltonian diffeomorphisms ${\phi}_k$ of an exact symplectic manifold, all of which are "graphical" in the sense that their graphs are identified by a Darboux-Weinstein chart with the image of a one-form. We show by an elementary argument that if the ${\phi}_k$ $C^0$-converge to the identity, then their Calabi invariants converge to zero. This generalizes a result of Oh, in which the ambient manifold was the two-disk and an additional assumption was made on the Hamiltonians generating the ${\phi}_k$. We discuss connections to the open problem of whether the Calabi homomorphism extends to the Hamiltonian homeomorphism group. The proof is based on a relationship between the Calabi invariant of a $C^0$-small Hamiltonian diffeomorphism and the generalized phase function of its graph.