• 제목/요약/키워드: evolution optimization

검색결과 404건 처리시간 0.024초

The Importance of FACS Analysis in the Development of Aptamers Specific to Pathogens

  • Moon, Ji-Hea;Kim, Giyoung;Park, Saet Byeol;Lim, Jongguk;Mo, Changyeun
    • Journal of Biosystems Engineering
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    • 제39권2호
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    • pp.111-114
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    • 2014
  • Purpose: This review aims to introduce aptamers and the methods of its development to improve the sensitivity and selectivity to target bacteria. In this review, we have highlighted current developments and directions in the pathogen detection based on aptamers. Background: Aptamers, the specific nucleic acid sequences, can bind to targets with high affinity and specificity. Some of researches on the use of aptamers for the detection of pathogen have been reported in recent years. Aptamers have more applicability than antibodies for the development of pathogen detection using biosensor; such as easy to synthesis and labeling, lack of immunogenicity, and a low cost of production. However, only few reports on the development and use of aptamers for the detection of pathogen have been published. Review: Aptamers specific to pathogen are obtained by whole-cell systematic evolution of ligands by exponential enrichment (SELEX) process. SELEX process is composed of screening random oligonucleotide bound with target cells, multiple separation and amplification of nucleic acids, final identification of the best sequences. For improving those affinity and selectivity to target bacteria, optimization of multiple separating process to remove unbounded oligonucleotides from aptamer candidates and sorting process by flow cytometry are required.

Challenges and Issues of Resource Allocation Techniques in Cloud Computing

  • Abid, Adnan;Manzoor, Muhammad Faraz;Farooq, Muhammad Shoaib;Farooq, Uzma;Hussain, Muzammil
    • KSII Transactions on Internet and Information Systems (TIIS)
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    • 제14권7호
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    • pp.2815-2839
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    • 2020
  • In a cloud computing paradigm, allocation of various virtualized ICT resources is a complex problem due to the presence of heterogeneous application (MapReduce, content delivery and networks web applications) workloads having contentious allocation requirements in terms of ICT resource capacities (resource utilization, execution time, response time, etc.). This task of resource allocation becomes more challenging due to finite available resources and increasing consumer demands. Therefore, many unique models and techniques have been proposed to allocate resources efficiently. However, there is no published research available in this domain that clearly address this research problem and provides research taxonomy for classification of resource allocation techniques including strategic, target resources, optimization, scheduling and power. Hence, the main aim of this paper is to identify open challenges faced by the cloud service provider related to allocation of resource such as servers, storage and networks in cloud computing. More than 70 articles, between year 2007 and 2020, related to resource allocation in cloud computing have been shortlisted through a structured mechanism and are reviewed under clearly defined objectives. Lastly, the evolution of research in resource allocation techniques has also been discussed along with salient future directions in this area.

High-Rise Urban Form and Environmental Performance - An Overview on Integrated Approaches to Urban Design for a Sustainable High-Rise Urban Future

  • Yang, Feng
    • 국제초고층학회논문집
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    • 제5권2호
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    • pp.87-94
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    • 2016
  • High-rise as a building typology is gaining popularity in Asian mega-cities, due to its advantages in increasing volumetric density with limited land resources. Numerous factors contribute to the formation of high-rise urban form, from economical and institutional, environmental to socio-political. Environmental concerns over the impact of rapid urbanization in developing economies demand new thought on the link between urban environment and urban form. Outdoor and indoor climate, pedestrian comfort, and building energy consumption are all related to and impacted by urban form and building morphology. There are many studies and practices on designing individual "green" high-rise buildings, but far fewer studies on designing high-rise building clusters from the perspective of environmental performance optimization.. This paper focuses on the environmental perspective, and its correlation with the evolution of the high-rise urban form. Previous studies on urban morphology in terms of environmental and energy performance are reviewed. Studies on "parameterizing" urban morphology to estimate its environmental performance are reviewed, and the possible urban design implications of the study are demonstrated in by the author, by way of a microclimate map of the iconic Shanghai Xiao Lujiazui CBD. The study formulates the best-practice design guidelines for creating walkable and comfortable outdoor space in a high-rise urban setting, including proper sizing of street blocks and building footprint, provision of shading, and facilitating urban ventilation.

밝기변화에 강인한 Genetic Programming 기반의 비파라미터 다중 컬러 검출 모델 (Genetic Programming based Illumination Robust and Non-parametric Multi-colors Detection Model)

  • 김영균;권오성;조영완;서기성
    • 한국지능시스템학회논문지
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    • 제20권6호
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    • pp.780-785
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    • 2010
  • 본 논문은 물체인식이나 영상추적에 사용되는 컬러검출을 위한 GP(Genetic Programming) 기반의 컬러검출 모델을 제안한다. 기존의 컬러검출은 기본적인 RGB 모델에 대한 선형, 비선형 함수의 변환을 사용하거나, 최적화 기법이나 학습기법에 의해 조명 변화에 개선된 컬러 모델을 사용하고 있다. 하지만 대부분의 경우 색상 채널간의 간섭에 의해 다양한 색상에 대한 분류가 어렵고, 조명변화에 강인하지 못하다. 본 연구에서는 GP의 최적화된 학습기법과 모델 생성 기법을 통해 조명변화에 강인하고, 다중의 색상 검출이 가능하며, 파라미터 설정이 필요 없는 컬러 모델을 제안한다. 제안된 방법을 다양한 색상과 조명환경이 다른 영상에 대해서 기존 컬러모델과 비교 분석하였다.

스키마 공진화 기법을 이용한 자율이동로봇의 행동제어 (Behavior Control of Autonomous Mobile Robot using Schema Co-evolution)

  • Sun, Joung-Chi;Byung, Jun-Hyo;Bo, Sim-Kwee
    • 한국지능시스템학회:학술대회논문집
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    • 한국퍼지및지능시스템학회 1998년도 춘계학술대회 학술발표 논문집
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    • pp.123-126
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    • 1998
  • The theoretical foundations of GA are the Schema Theorem and the Building Block Hypothesis. In the Meaning of these foundational concepts, simple genetic algorithm(SGA) allocate more trials to the schemata whose average fitness remains above average. Although SGA does well in many applications as an optimization method, still it does not guarantee the convergence of a global optimum. Therefore as an alternative scheme, there is a growing interest in a co-evolutionary system, where two populations constantly interact and co-evolve in contrast with traditional single population evolutionary algorithms. In this paper, we propose a new design method of an optimal fuzzy logic controller using co-evolutionary concept. In general, it is very difficult to find optimal fuzzy rules by experience when the input and/or output variables are going to increase. So we propose a co-evolutionary method finding optimal fuzzy rules. Our algorithm is that after constructing two population groups m de up of rule vase and its schema, by co-evolving these two populations, we find optimal fuzzy logic controller. By applying the proposed method to a path planning problem of autonomous mobile robots when moving objects exist, we show the validity of the proposed method.

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Niche Meta 유전 알고리즘을 이용한 2자유도 이동 로봇의 퍼지 제어기 설계 (Fuzzy Controller Design of 2 D.O.F of Wheeled Mobile Robot using Niche Meta Genetic Algorithm)

  • 김성회;김기열
    • 정보학연구
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    • 제5권4호
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    • pp.73-79
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    • 2002
  • 본 논문에서는 퍼지 제어기의 설계를 위한 다중 돌연변이 연산자를 갖는 Niche Meta 유전 알고리즘을 제안한다. 제안된 알고리즘에서 유전자는 유전 알고리즘에 사용되는 교배율이나 돌연변이율과 같은 구조 매개변수와 퍼지 제어기의 입$cdot$출력 소속함수를 나타내는 매개변수로 구성된다. 제안된 알고리즘은 부개체군들에 대해 퍼지 제어기의 소속함수의 매개변수를 최적화시키는 지역적 탐색을 수행하면서 전체 개체군에 대해서 최적의 구조 매개변수에 대한 전역적인 탐색을 수행한다. 다중 돌연변이 연산자는 지역적 진화의 결과에 따라 진화에 가장 적합한 돌연변이 방법으로 선택된다. 제안된 알고리즘의 효율성을 입증하기 위해 2 자유도 구륜 이동 로봇에 대한 모의 실험을 수행한다.

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An evolutionary hybrid optimization of MARS model in predicting settlement of shallow foundations on sandy soils

  • Luat, Nguyen-Vu;Nguyen, Van-Quang;Lee, Seunghye;Woo, Sungwoo;Lee, Kihak
    • Geomechanics and Engineering
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    • 제21권6호
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    • pp.583-598
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    • 2020
  • This study is attempted to propose a new hybrid artificial intelligence model called integrative genetic algorithm with multivariate adaptive regression splines (GA-MARS) for settlement prediction of shallow foundations on sandy soils. In this hybrid model, the evolution algorithm - Genetic Algorithm (GA) was used to search and optimize the hyperparameters of multivariate adaptive regression splines (MARS). For this purpose, a total of 180 experimental data were collected and analyzed from available researches with five-input variables including the bread of foundation (B), length to width (L/B), embedment ratio (Df/B), foundation net applied pressure (qnet), and average SPT blow count (NSPT). In further analysis, a new explicit formulation was derived from MARS and its accuracy was compared with four available formulae. The attained results indicated that the proposed GA-MARS model exhibited a more robust and better performance than the available methods.

유전 알고리즘을 이용한 최적부하절체에 의한 배전계통의 신뢰도 평가 (Reliability evaluation of distribution systems vs. the optimal load transferring using genetic algorithms)

  • 한성호;최준호;최도혁;이욱;최대섭;김재철
    • 대한전기학회:학술대회논문집
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    • 대한전기학회 1996년도 하계학술대회 논문집 B
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    • pp.862-864
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    • 1996
  • This paper presents a new approach to evaluate reliability indices of electric distribution systems using genetic algorithm(GA). The use of reliability evaluation is an important aspect of distribution system planning and operation to adjust the reliability level of each area. In this paper, the reliability model is based on the optimal load transferring problem to minimize over load generated load point outage in each sub-section. This kind of the approach is one of the most difficult procedure which becomes a combination problems. A new approach using GA Was developed for this problem. We proposed a tree search algorithm which satisfied the tree constraint. GA is general purpose optimization techniques based on principles inspired from the biological evolution such as natural selection, genetic recombination and survival of the fittest Test results for the model system with 24 nodes and 29 branches are reported in the paper.

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유한요소법을 이용한 헤어핀 형 열 교환기의 튜브 확관에 대한 연구 (Study of Tube Expansion to Produce Hair-Pin Type Heat Exchanger Tubes using the Finite Element Method)

  • 홍석무;현홍철;황지훈
    • 소성∙가공
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    • 제23권3호
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    • pp.164-170
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    • 2014
  • To predict the deformation and fracture during tube expansion using the finite element (FE) method, a material model is considered that incorporates the damage evolution due to the deformation. In the current study, a Rice-Tracey model was used as the damage model with inclusion of the hydrostatic stress term. Since OFHC Cu is not significantly affected by strain rate, a Hollomon flow stress model was used. The material parameters in each model were obtained by using an optimization method. The objective function was defined as the difference between the experimental measurements and FE simulation results. The parameters were determined by minimizing the objective function. To verify the validity of the FE modeling, cross-verification was conducted through a tube expansion test. The simulation results show reasonable agreement with the experiments. The design for a minimum diameter of expansion tube using the FE modeling was verified by a simplified tube expansion test and simulation results.

A Study on 3-Dimensional Profilometry of Steam Generator Tube Using a New Eddy Current Probe

  • Kim, Young-Kyu;Song, Myung-Ho;Choi, Myung-Sik
    • 비파괴검사학회지
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    • 제30권3호
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    • pp.225-235
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    • 2010
  • There are many types of the geometric transitions such as dent, bulge, protrusion, expansion, etc, on the inner and outer surfaces of heat exchanger tubes, steam generator tubes, and condenser tubes of nuclear power plants. Such geometric transition causes a local residual stress in heat exchanger tubes and acts as a structural factor accelerating the evolution of defects, in particular stress corrosion cracks. In the conventional eddy current test methods, the bobbin coil profilometry can provide 2-dimensional geometric information on the variation of the average inner diameter along the tube length, but the 3-dimensional distribution and the quantitative size of a local geometric transition existing in the tube cannot be measured. In this paper, a new eddy current probe, developed for the 3-dimensional profile measurement, is introduced and its superior performance is compared with that from the conventional bobbin coil profilometry for the various types of geometric transition. Also, the accuracy of the probe for the quantitative profile measurement is verified by comparing the results with that from the laser profilometry. It is expected that the new eddy current probe and techniques can be effectively used for an optimization of the tube expansion process, and the management of tubes with geometric transitions in service.