• Title/Summary/Keyword: evolution family

Search Result 395, Processing Time 0.028 seconds

Prosobranch Family Velutinidae (Gastropoda) in Cold and Temperate Waters of the Northern Hemisphere: History, Biogeography, Evolution and Chorology

  • Gulbin, V.V.
    • Ocean Science Journal
    • /
    • v.40 no.1
    • /
    • pp.45-54
    • /
    • 2005
  • The history of investigation of the family Velutinidae from 1776 to the present day is briefly described in the last part of this review; the contemporary system of the family, consisting of 39 species and subspecies, belonging to 17 genera and subgenera, and three subfamilies, is presented here. A biogeographic analysis of the fauna has been made, the history of origin and development of the family, vertical distribution and relation to substrates have been described in this work.

Evolution of the Mir-155 Family and Possible Targets in Cancers and the Immune System

  • Xie, Guang-Bing;Liu, Wei-Jia;Pan, Zhi-Jun;Cheng, Tian-Yin;Luo, Chao
    • Asian Pacific Journal of Cancer Prevention
    • /
    • v.15 no.18
    • /
    • pp.7547-7552
    • /
    • 2014
  • The mir-155 family is not only involved in a diversity of cancers, but also as a regulator of the immune system. However, the evolutionary history of this family is still unclear. The present study indicates that mir-155 evolved independently with lineage-specific gain of miRNAs. In addition, arm switching has occurred in the mir-155 family, and alternative splicing could produce two different lengths of ancestral sequences, implying the alternative splicing can also drive evolution for intragenic miRNAs. Here we screened validated target genes and immunity-related proteins, followed by analyzation of the mir-155 family function by high-throughput methods like the gene ontology (GO) and Kyoto Eneyclopedin of Genes and Genemes (KEGG) pathway enrichment analysis. The high-throughput analysis showed that the CCND1 and EGFR genes were outstanding in being significantly enriched, and the target genes cebpb and VCAM1 and the protein SMAD2 were also vital in mir-155-related immune reponse activities. Therefore, we conclude that the mir-155 family is highly conserved in evolution, and CCND1 and EGFR genes might be potential targets of mir-155 with regard to progress of cancers, while the cebpb and VCAM1 genes and the protein SMAD2 might be key factors in the mir-155 regulated immune activities.

Multiple Facets of Sox Gene (SOX 유전자의 다양성)

  • 홍경원;김희수
    • Journal of Life Science
    • /
    • v.14 no.4
    • /
    • pp.716-725
    • /
    • 2004
  • Sox protein family, a transcription factor, has been found in whole animal kingdom, and contains a sequence-specific DNA binding domain called high mobility group domain (HMG). The Sox protein family based on the amino acid sequence of HMG domain was classified into 10 groups. Each group of Sox family shows significant conservation from nematode to human. The HMG domain affect to various developmental cell differentiation through binding to enhancer and regulating other transcription factors. Recently, many molecular biologists focus their research on the illustration of Sox-related disease, evolution and phylogeny. Especially, stem cell research with Sox gene family is indispensable field for understanding of their biological functions. The understanding of Sox genes may contribute to understand their role in human genetic disease and whole animal evolution.

A Study on Stages of Development of Corporate Family-Friendly Policies and Programs (일-가족 조화를 위한 가족친화적 기업정책의 발달단계에 관한 연구)

  • Choi Sung-Il;Yoo Gye-Sook
    • Journal of Families and Better Life
    • /
    • v.24 no.4 s.82
    • /
    • pp.51-73
    • /
    • 2006
  • The purpose of this study is to introduce the evolution of corporate family-friendly policies and programs, a recent business issue throughout the world. In addition, this study suggests implications for a corporate reference guide to work-family policies and programs by providing a comparative analysis of the typical stages of development of U.S. corporate family-friendly policies and programs, and by presenting model initiatives of Korean and American family-friendly companies. Just as technological changes at the time of the Industrial Revolution altered the relationship between workers and their work, more recent technological advances have again transformed this relationship, offering the promise of a society in which work demands a smaller portion of the worker's time and permitting the worker more freedom and control over work conditions. These new work arrangements have the promise of producing a new paradigm for work and family, based on which many industrialized nations have developed family-friendly policies already. Family-friendly policies and programs can be grouped into four discernable stages in the evolution of a corporate work-family agenda. According to these stages, most companies in Korea are in the predevelopment stage or stage 1. Development of scales to assess company family-friendliness is needed to create a family-friendly workplace environment, policies, and programs. It is critical that companies have champions who have the vision to step out in kent, and the determination to ensure that the family-friendly programs are solidly grounded. Companies should develop their work-family initiatives as an integral part of a program for managing diversity focusing on needs of women and minority employees.

The Role of a Floral Identity Gene LFY in Plant Morphological Evolution

  • Park, Young-Doo;Yoon, Ho-Sung
    • Korean Journal of Plant Taxonomy
    • /
    • v.37 no.4
    • /
    • pp.323-333
    • /
    • 2007
  • The degree to which parallel evolution utilizes the same genetic mechanisms indicates the degree to which developmental processes constrain or channel phenotypic evolution. A transgenetic strategy was used to elucidate the role of one floral meristem identity gene, LEAFY (LFY), in the evolution of rosette flowering, a plant architecture that has evolved in parallel in several lineages of the mustard family, Brassicaceae. The LFY genes from three rosette flowering species were cloned and introduced into a species with the ancestral architecture, and results indicated that changes at the LFY locus contributed to the evolution of rosette flowering in two of the three lineages, but that in each lineage a different set of genetic partners was involved. Also, LFY was shown to play a role in the evolution of flower size. Transgenetic strategy may be useful in the study of plant morphological evolution and parallelism.

Perspectives provided by leopard and other cat genomes: how diet determined the evolutionary history of carnivores, omnivores, and herbivores

  • Kim, Soonok;Cho, Yun Sung;Bhak, Jong;O'Brian, Stephen J.;Yeo, Joo-Hong
    • BMB Reports
    • /
    • v.50 no.1
    • /
    • pp.3-4
    • /
    • 2017
  • Recent advances in genome sequencing technologies have enabled humans to generate and investigate the genomes of wild species. This includes the big cat family, such as tigers, lions, and leopards. Adding the first high quality leopard genome, we have performed an in-depth comparative analysis to identify the genomic signatures in the evolution of felid to become the top predators on land. Our study focused on how the carnivore genomes, as compared to the omnivore or herbivore genomes, shared evolutionary adaptations in genes associated with nutrient metabolism, muscle strength, agility, and other traits responsible for hunting and meat digestion. We found genetic evidence that genomes represent what animals eat through modifying genes. Highly conserved genetically relevant regions were discovered in genomes at the family level. Also, the Felidae family genomes exhibited low levels of genetic diversity associated with decreased population sizes, presumably because of their strict diet, suggesting their vulnerability and critical conservation status. Our findings can be used for human health enhancement, since we share the same genes as cats with some variation. This is an example how wildlife genomes can be a critical resource for human evolution, providing key genetic marker information for disease treatment.

Identification and Phylogeny of Long Terminal Repeat Elements of Human Endogenous Retrovirus HERV-S (인간 내생 레토르바이러스 HERV-S의 LTR엘리먼트의 동정과 계통분류)

  • 최주영;이주민;전승희;신경미;이지원;이원호;김희수
    • Journal of Life Science
    • /
    • v.11 no.5
    • /
    • pp.400-404
    • /
    • 2001
  • A new human endogenous retroviral family (HERV-S) has recently been identified from human X chromosome. It is 6.7 kb in length and has a typical retroviral structure with LTR-gag-pol-env-LTR. Using the PCR and sequencing approach, we investigated LTR elements of the HERV-S family from a human genomic DNA. Four LTR elements (HSL-1, HSL-5, HSL-10, HSL-11) were identified and have a high degree of sequence similarity(96-99%) with that of the HERV-S. Phylogenetic analysis from the HERV-S family indicated that the LTR elements were mainly divided into 2- groups through evolutionary divergence in the primate evolution. Further investigation of the HERV-S LTR elements in primates may cast light on the integration timing into the primate genome and understanding of human evolution.

  • PDF

Molecularr Analysis of $\alpha$-Glucosidase from Microorganism

  • Kimura, Atsuo
    • Proceedings of the Korean Society for Applied Microbiology Conference
    • /
    • 2001.06a
    • /
    • pp.73-76
    • /
    • 2001
  • $\alpha$-Glucosidase contributing $\alpha$-glucan metabolism in microorganisms is characterized by the variety in substrate recognition. Recent studies on microbial enzymes show that $\alpha$-glucosidases are divided into two groups, family I and family n, in which family I enzymes have four conserved catalytic-regions of $\alpha$-amylase family. The presentation focusing on the difference of the $\alpha$-glucosidase families reviews i) the catalytic amino-acid residues of nucleophile and acid/base catalyst, and ii) the molecular evolution of two families.

  • PDF