• 대한한방소아과학회지
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• 제35권1호
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• pp.122-138
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• 2021

Objectives The purpose of this study is to widely utilize the clinical practice guideline for autism spectrum disorder (ASD) by investigating parents who have children with ASD about their perception in ASD and their thoughts on Korean medicine treatment to treat ASD. Methods We conducted a survey on 'perception of ASD' and 'perception and preference of Korean medicine treatment for ASD' on the parents of 22 children with ASD (age 4-6) who visited department of pediatrics of Korean medicine at Kyunghee University Korean medicine hospital at Gangdong and Kyunghee University Korean medicine hospital. Results Of the parents, 20 (90.91%) said their children had no experience with Korean medicine treatment. Among them, 11 (35.48%) chose 'I didn't know that Korean medicine treats ASD' for the reason (multiple choice). When questioned what the worries are for Korean medicine treatment, 13 (30.95%) chose 'worries about probability of side effects of herbal medicine' as the most worrisome reason (multiple choice). On the question about the necessity of Korean medicine for the treatment of ASD, most chose 'Korean medicine treatments are necessary for children with ASD' (9, 40.91%). Conclusions It is necessary to develop a clinical practice guideline that reflects comprehensive evidence for side effects as well as the effectiveness of Korean medicine for ASD, and is necessary to promote the effectiveness and evidence-based Korean medicine treatment to patients and their caregivers through various distribution tools.

• 대한교통학회지
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• 제24권5호
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• pp.89-108
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• 2006

우리나라도 2000 년에 65세 이상 고령자 인구가 전인구의 7%에 도달하며서 소위 고령화 사회에 진입하게 되었고 앞으로 25년간 우리나라 고령자인구의 증가율은 세계적으로 유례없이 급속할 것으로 예상된다. 이러한 측면에서 최근 고령화 문제가 사회적인 이슈로 대두됨에 따라 교통시설물 계획 등에서 고령인구의 통행특성을 고려한 계획 및 설계가 필수적으로 요구되어지고 있다 하지만, 기존의 교통존 혐의 집계분석 방법론에서는 일반인과 고령자의 평균값을 사용함으로써 고령자의 통행 특성 및 사회경제적 특성을 고려하는데 한계를 가지고 있다. 따라서 본 연구는 일반인과 다른 고령자의 통행특성을 분석하기 위해 네스티드 로지모형을 이용하여 개인의 통행특성을 반영할 수 있는 비집계분석의 방법론으로 활동 스케줄링 모형을 구축하고 정립하였다. 본 연구에서의 분석결과 일반인과 비교해 고령자의 통행특성은 직장인과 비직장인 모두에서 출발시간과 수단 선택에서 큰 차이를 가지는 것으로 분석되었다 이러한 개인 통행특성의 차이를 간과한 기존의 교통존 중심의 집계분석 방법론으로 장래 수요 예측시에 큰 편이를 초래할 것으로 예상된다 따라서 본 연구는 개인통행특성을 고려하기 위해 활동기반모형의 필요성을 강조할 수 있는 좋은 선행과제가 될 것으로 기대한다 또한, 활동기반분석의 지속적인 연구 및 이에 대한 개발은 현재 대두되고 있는 도로사업 평가의 신뢰성, 향후교통시설물 계획 및 설계 평가에 중요 요소로 인식되는 교통량 예측 등에 대한 신뢰성 향상에 많은 기회를 할 것으로 판단된다

• 아태비즈니스연구
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• 제7권1호
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• pp.59-69
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• 2016

An extensive body of research on the effects of country-of-origin has emerged in the international marketing and business literature streams. Nonetheless, extant studies do not satisfactorily demonstrate whether and how a foreign firm's choice of market entry mode influences consumers' purchase intentions of its product in country-related affect contexts. Using a survey and an experimental design, we aimed to provide evidence of the effects of the choice on consumers' evaluation and attitude of its product in an animosity context and in a national image context. Through the survey, we collected data regarding consumer animosity, national image, product evaluation, and product attitude from 185 university students and tested the hypotheses that consumer animosity and national image have effects on foreign product evaluation and attitude. The results of the survey research show that personal animosity has a negative effect on consumers' evaluation of foreign products and that a country's image regarding economics has positive effects on consumers' attitude toward foreign products as well as consumers' evaluation of foreign products. In the experimental design, we divided subjects into four groups and exposed them to several descriptions of hypothetical purchase situations. Conducting a 2 (market entry modes)${\times}2$ (country-of-origin) ANOVA, we tested the hypothesis that a market entry mode influences foreign product evaluation and attitude. The results of the experimental study reveal that in a high country-related product association (Germany), market entry modes have insignificant effects on foreign product evaluation and attitude. In addition, in a low country-related product association (China), international partnership has more positive effects on foreign product evaluation and attitude than does exporting.

• 응용통계연구
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• 제26권4호
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• pp.623-634
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• 2013

본 연구에서는 교통 분석존(서울시 행정동) 단위별로 대중교통 수단(버스, 도시철도)선택에 있어서 공간 상관성이 존재하는지 여부를 대중교통카드 자료를 기반으로 제시한다. 분석결과 버스를 탑승한 비율이 높은 지역들이 서로 이웃하여 그룹을 형성하고 있으며, 이들 지역은 도시철도 역사의 수가 버스 정류장에 비해 매우 적기 때문인 것으로 분석되었다. 버스에 탑승한 비율이 비슷한 그룹 간에는 공간 상관성이 존재하는 것으로 통계분석결과 나타났으며, 이러한 공간상관성은 향후 대중교통 수단선택 모형 구축에 고려할 수 있을 것으로 판단된다. 대중교퉁 수단선택에 있어 공간상관성의 존재는 대중교통 운영기관이 향후 대중교통카드를 기반으로 대중교통 노선계획, 운영계획을 수립함에 있어 중요한 정보가 될 것으로 기대된다.

• 대한교통학회지
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• 제29권1호
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• pp.95-102
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• 2011

본 연구에서는 Solomon이 제안한 속도편차 (주행속도와 평균속도와의 차) 개념을 이용하여 주행위험도를 정립하고, 순서프로빗모형을 이용하여 주행속도선택 기반 주행위험도평가모델을 개발한다. 제안모델을 고속도로의 차내 교통안전정보 제공효과 평가실험에 적용하여, 주행위험에 미치는 다양한 요인의 효과를 분석한 결과, 다음과 같은 연구결과가 도출되었다. 첫째, 남성이 여성보다, 경력 운전자가 초보 운전자보다, 교통사고의 경험이 적은 운전자가 고속도로를 안전하게 주행할 확률이 높다. 둘째, 고속도로를 오후에 주행하는 경우, 도로표면이 젖어있는 경우, 교통량이 한산하여 서비스수준이 너무 좋은 경우 주행위험도는 증가한다. 셋째, 경사진 회전구간을 주행하는 경우와 도로연장이 긴 곡선부 구간을 주행하는 경우 주행위험도는 증가한다. 한편, 주행위험도 증가는 차내 교통안전정보를 제공함으로써 어느 정도 감소될 수 있는 것으로 나타나 차내 교통안전정보의 제공의 중요성이 확인되었다. 본 제안 모델은 새로 도입된 교통안전시설물의 교통안전도 효과를 평가 시 교통사고 자료가 부족하거나 없는 경우 교통안전도를 평가하는데 활용할 수 있다.

• Journal of Gastric Cancer
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• 제24권1호
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• pp.108-121
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• 2024

Anastomotic leaks and fistulas are significant complications of gastric surgery that potentially lead to increased postoperative morbidity and mortality. Surgical intervention is reserved for cases with severe symptoms or hemodynamic instability; however, surgery carries a higher risk of complications. With advancements in endoscopic treatment options, endoscopic approaches have emerged as the primary choice for managing these complications. Endoscopic clipping is a traditional method comprising 2 main categories: through-the-scope clips and over-the-scope clips. Through-the-scope clips are user friendly and adaptable to various clinical scenarios, whereas over-the-scope clips can close larger defects. Another promising approach is endoscopic stent insertion, which has shown a high success rate for leak closure, although vigilant monitoring is required to monitor stent migration. Infection control is essential in post-surgical leakage cases, and endoscopic internal drainage provides a relatively safe and noninvasive means to manage fluids, contributing to infection control and wound healing promotion. Endoscopic suturing offers full-thickness wound closure, but requires additional training and endoscopic versatility. As a promising tool, endoscopic vacuum therapy potentially surpasses stent therapy by draining inflammatory materials and closing defects. Furthermore, the use of tissue sealants, such as fibrin glue and cyanoacrylate, has been reported to be effective in selected situations. The choice of endoscopic device should be tailored to individual cases and specific patient conditions, with careful consideration of the nature of the defect. Further extensive studies involving larger patient populations are required to provide more robust evidence on the efficacy of endoscopic approach in managing post-gastric anastomotic leaks.

• 천문학회보
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• 제38권2호
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• pp.56.1-56.1
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• 2013

Supernovae type Ia (SNe Ia) cosmology is providing the only direct evidence for the presence of dark energy. This result is based on the assumption that the look-back time evolution of SNe Ia luminosity, after light-curve shape correction, would be negligible. However, the most recent compilation of SNe Ia data shows systematic difference in the Hubble residual (HR) between the E and Sd/Irr galaxies, indicating that the light-curve fitters used by the SNe Ia community cannot quite correct for a large portion of the population age effect. In order to investigate this possibility more directly, we have obtained low-resolution spectra for 30 nearby early-type host galaxies. This data set is used to estimate the luminosity-weighted mean ages and metallicities of host galaxies by employing the population synthesis models. We found an interesting trend between the host galaxy age and HR, in the sense that younger galaxies have positive residuals (i.e., light-curve corrected SNe Ia luminosity is fainter). This result is rather independent of the choice of the population synthesis models employed. Taken at face value, this age (evolution) effect can mimic a large fraction of the HR used in the discovery of the dark energy. This result is significant at 1.4 - 3 sigma levels, depending on the light curve fitters adopted, and further observations and analyses are certainly required to confirm the trend reported here.

• Journal of Dental Anesthesia and Pain Medicine
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• 제19권6호
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• pp.323-341
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• 2019

Background: Local anesthetics alone or in combination with adjuncts, such as oral medications, have routinely been used for pain control during endodontic treatment. The best clinical choice amongst the vast numbers of agents and techniques available for pain control for irreversible pulpitis is unclear. This network meta-analysis combined the available evidence on agents and techniques for pulpal anesthesia in the maxilla and mandible, in order to identify the best amongst these approaches statistically, as a basis for future clinical trials. Methods: Randomized trials in MEDLINE, DARE, and COCHRANE databases were screened based on inclusion criteria and data were extracted. Heterogeneity was assessed and odds ratios were used to estimate effects. Inconsistencies between direct and indirect pooled estimates were evaluated by H-statistics. The Grading of Recommendation, Assessment, Development, and Evaluation working group approach was used to assess evidence quality. Results: Sixty-two studies (nine studies in the maxilla and 53 studies in the mandible) were included in the meta-analysis. Increased mandibular pulpal anesthesia success was observed on premedication with aceclofenac + paracetamol or supplemental 4% articaine buccal infiltration or ibuprofen+paracetamol premedication, all the above mentioned with 2% lignocaine inferior alveolar nerve block (IANB). No significant difference was noted for any of the agents investigated in terms of the success rate of maxillary pulpal anesthesia. Conclusion: Direct and indirect comparisons indicated that some combinations of IANB with premedication and/or supplemental infiltration had a greater chance of producing successful mandibular pulpal anesthesia. No ideal technique for maxillary anesthesia emerged. Randomized clinical trials with increased sample size may be needed to provide more conclusive data. Our findings suggest that further high-quality studies are required in order to provide definitive direction to clinicians regarding the best agents and techniques to use for mandibular and maxillary anesthesia for irreversible pulpitis.

• Archives of Plastic Surgery
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• 제35권3호
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• pp.312-315
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• 2008

Purpose: Amelanotic melanoma represents a melanoma with an absence or a small number of melanin pigments and comprises 2% of all melanomas. These melanomas are frequently misdiagnosed, probably because of its nonspecific clinical features and difficulty in diagnosis, resulting in delayed diagnosis and treatment. We report a patient with amelanotic melanoma, who underwent surgical treatment with sentinel lymph node biopsy using gamma probe. Methods: A 32-year-old female was presented with a slowly growing ill-defined, hypopigmented nonerythematous lesion with nail defect on right index finger tip. Preoperative punch biopsy was performed, showing an amelanotic melanoma. Sentinel lymph node biopsy was done using gamma probe(Crystal probe system, CRYSTAL PHOTONICS GmbH, Germany) and confirmed no evidence of regional lymph node metastases. The patient underwent amputation at the proximal interphalangeal joint. Results: Histopathologic findings showed superficial spreading melanoma. There were no melanin pigments in Hematoxylin & Eosin stain but positive immunohistochemical stainings for S-100 protein and Hmb45, which were consistent with amelanotic melanoma. Patient's postoperative course was uneventful without any complication and had no evidence of recurrence of tumor in 6 months follow-up period. Conclusion: Amelanotic melanoma is extremely rare subtype of malignant melanoma with histopathologic findings of atypical melanocytes without melanin pigments. Early detection is crucial since survival is strongly related to tumor thickness and tissue invasion at the time of diagnosis. Wide excision is the treatment of choice and other conjunctive therapy has not been successful.

• Journal of the Korean Association of Oral and Maxillofacial Surgeons
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• 제32권6호
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• pp.598-602
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• 2006

저자 등은 우측 측방 경부 및 이하부에 발생한 침습성 지방종을 가진 57세 여자 환자에서 이하선 천엽 절제술과 함께 외과적 절제술로 종물을 제거하였다. 술 후 약 2.5년 동안 추적 관찰한 결과 현재까지 재발 등 이상 소견 없이 기능적, 심미적으로 양호한 결과를 얻었기에 문헌고찰과 함께 보고함으로써 지방종의 진단과 치료에 도움이 되고자 한다.