• Title/Summary/Keyword: evaluation of preservation function

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Comparative Study of Prolonged Preservation Methods in Rabbit Heart for Transplantation (이식을 위한 가토심장의 장기 보존방법에 관한 비교 연구)

  • Jo, Hyeong-Gon;Kim, Su-Hyeon;Kim, Song-Myeong
    • Journal of Chest Surgery
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    • v.30 no.1
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    • pp.1-10
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    • 1997
  • The successful cardiac transplantation depends partly on the donor heart preservation by a solution that will ensure recovery of myocardial function. The purpose of this study was to perform the evaluation of various preservation solutions and to accumulate the data on the requisites for ideal preservation solution. The experimental setup was the constant pressure Langendorffs perfusion system. Isolated rabbit hearts were perfused for 20minutes with unarm Krebs-Henseleit solution, stored for 4 hours in cold preservation solution after cardioplegia, and then were reperfused for 20minutes. The 4 experimental groups were prepared Hartmann's solution group (group 1, control), modified Euro-collins solution group(group II. MEC), modified University of Wisconsin group (group n, MUW), and CK solution(made by the author) group (group W, CK). The parameters for assessing the preservation ability were levels of enzymes in freezed myocardial tissues (lactate, creatine kinase-MB and adenosine deaminase), coronary flow. left ventricular developing pressure and dpldt. In conclusion, the ability of preservation for isolated rabbit heart was excellent in CK solution and modified University of Wisconsin solution, and poor in modified Euro-collins solution, compared with Hartmann solution. CK solution has low potassium concentrations(34.2mEq/L) and includes various substrates to be salutary on myocardial preservation. This fact may indicates the necessity of further refinements in selection or composition of electrolytes and substrates.

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Quality Changes of Smoked Duck Meat Amended with Curcuma longa L. during Storage (울금을 첨가한 오리 훈연육의 저장 중 품질변화)

  • Lee, In Ok;Ro, Hee Kyong
    • Journal of the Korean Society of Food Culture
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    • v.34 no.1
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    • pp.68-74
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    • 2019
  • This study was conducted to evaluate the effects of adding gradually increasing concentrations of turmeric extract (0, 0.1, 0.2, and 0.4%) to smoked duck meat on its chromaticity, antibiosis, and antiseptic degree against food poisoning bacteria, number of bacteria, lipid rancidity, sensory evaluation, and preference. The brightness, red color intensity and yellow color intensity changed significantly when 0.2% turmeric extract was added and the sodium nitrate concentration was reduced. Additionally, no antibiosis or antiseptic activities against food poisoning bacteria were observed in any turmeric treated samples, whereas the number of bacteria was increased in control samples compared to turmeric treated samples after 10 days of preservation. The TBARS value decreased during storage when turmeric extract concentration increased, resulting in positive sensory evaluation of its color, succulence, taste and hardness. In the preference test, the surface and meat color increased as the concentration of turmeric extracts increased. Hardness was highest at 0.2%, whereas taste was highest between 0.2 and 0.4%. The overall preference test was highest for the 0.2% extract samples. Overall, the results indicated that addition of 0.2% turmeric to smoked duck meat will lead to better nutrition, function, and overall preference.

An Evaluation of Environmental-Control Function on Forest Using GIS (GIS를 활용한 산림녹지의 환경조절적 기능 평가)

  • Lee, Woo-Sung;Jung, Sung-Gwan
    • Journal of the Korean Association of Geographic Information Studies
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    • v.14 no.4
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    • pp.102-115
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    • 2011
  • The purpose of this study is to establish the evaluation model through the systematic process of selecting the indicators and to evaluate the environmental-control function on forest using GIS in Deagu for the sustainable forest planning. The 35 indicators as basic items were selected by literature review and those were squeezed into the 29 indicators through expert brainstorming. Also, the 8 indicators to evaluate environmental-control function were selected by the first survey and the 5 final indicators such as carbon sink, temperature decrease, wind formation, water circulation, air purification were determined by MCB analysis using the second survey. The evaluation model was established through the weight of each indicator by AHP analysis using the third survey. According to the result of evaluating the environmental-control function on forest, the functions around the top area of Mt. Ap, Mt. Biseul, Mt. Palgong had more than 66 scores. On the other hand, the functions around Mt. Waryong and forest of Chilgok in Buk-gu had less than 40 scores. It is necessary to improve the function through the sustainable restoration and management in case of forest that the environmental-control function was lower. Furthermore, these results will be able to be utilized as basic data in order to establish the preservation area and control development area at the urban, environmental, and forest planning.

The Effect of Chordae Preservation in Mitral Valve Replacement (승모판막 치환술에 있어 건삭 보존의 효과)

  • 김공수;조중구;구자홍;김태호
    • Journal of Chest Surgery
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    • v.32 no.4
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    • pp.353-357
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    • 1999
  • Background: Mitral valve replacement(MVR) with chordal preservation in patients with mitral vlavular disease has been proven to be beneficial for left ventricular function and for reduction of postoperative complication. Material and Method: From January 1995 to July 1996, the early postoperative results of mitral valve replacement were compared between 20 patients who underwent chordae resection(classic MVR group) and 10 patients who underwent chordae preservation(preservation MVR group) in the Department of Thoracic and Cardiovascular Surgery, Chunbuk National University Hospital. Result: There was no significant difference between the two groups in age, sex, NYHA functional class, cardiothoracic ratio, echocardiographic finding, cardiopulmonary bypass time and aortic cross clamping time. The difference between preoperative and postoperative cardiothoracic ratio after 3 months was not statistically significant. At echocardiographic left ventricular evaluation, ejection fraction and fractional shortening decreased slightly in the preservation group then preoperative value (p=0.47, p=0.12), however, decreased significantly in the classic MVR group(p=0.03, p=0.04), and were statistically significant between the two groups(p=0.03, p=0.02). Conclusion: We conclude that MVR with chorda preservation seems to have a beneficial effect on postoperative left ventricular performance in mitral valve disease than the classic MVR.

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Clinical Experiences of Multiple Organ Failure after Surgery for Acquired Cardiovascular Disease

  • 김병열
    • Journal of Chest Surgery
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    • v.23 no.2
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    • pp.275-284
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    • 1990
  • A serious problem after cardiovascular surgery known as Multiple Organ Failure[MOF] whereby several vital organs successively demonstrate dysfunction in spite of intensive postoperative treatment has recently arisen. We have made a retrospective study of the clinical records of 137 patients who underwent cardiovascular surgery during past two years [1987-1988]. Fourteen patients [10%] developed multi-organ failure postoperatively with the results of seven death [50%]. In fatal group, preoperative poor cardiac function [Cardiac Index<2.0L/min/m2] was considered important prognostic factor and infection 5 disseminated intravascular coagulation complicating gastrointestinal bleeding were the leading cause of death. In conclusion, evaluation of multiple factors concerning multi-organ failure demonstrates preoperative poor functional preservation of vital organs is the main factor. So early diagnosis k management for each of the failing organs & prevention of infection are mandatory of the treatment of these critically ill patients.

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Functional Requirements of Data Repository for DMP Support and CoreTrustSeal Authentication

  • Kim, Sun-Tae
    • International Journal of Knowledge Content Development & Technology
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    • v.10 no.1
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    • pp.7-20
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    • 2020
  • For research data to be shared without legal, financial and technical barriers in the Open Science era, data repositories must have the functional requirements asked by DMP and CoreTrustSeal. In order to derive functional requirements for the data repository, this study analyzed the Data Management Plan (DMP) and CoreTrustSeal, the criteria for certification of research data repositories. Deposit, Ethics, License, Discovery, Identification, Reuse, Security, Preservation, Accessibility, Availability, and (Meta) Data Quality, commonly required by DMP and CoreTrustSeal, were derived as functional requirements that should be implemented first in implementing data repositories. Confidentiality, Integrity, Reliability, Archiving, Technical Infrastructure, Documented Storage Procedure, Organizational Infrastructure, (Meta) Data Evaluation, and Policy functions were further derived from CoreTrustSeal. The functional requirements of the data repository derived from this study may be required as a key function when developing the repository. It is also believed that it could be used as a key item to introduce repository functions to researchers for depositing data.

Isolated Working Canine Heart Perfusion Apparatus for Evaluation of Myocardial Protection Methods (심장기능 평가를 위한 견 적출심장 관류장치의 설계)

  • 이종국
    • Journal of Chest Surgery
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    • v.21 no.2
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    • pp.246-253
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    • 1988
  • An in vitro model providing with a recirculating perfusion apparatus using an isolated canine heart and its autogenous blood, which was prepared for study of myocardial protection method. This apparatus was easily used by quick connect system and maintained well heart function for about 2 hours. The Langendorff perfusion was initiated for a 10 minute period by introducing perfusate at 37` into the aorta from aortic reservoir located 100 cm above the heart. The isolated perfused working canine heart model was a left heart preparation in which oxygenated perfusion medium [at 37K] entered the cannulated left atrium at a constant flow rate [900ml/ min] under 20 mmHg overflow system and was spontaneously ejected[no electrical pacing] via an cannula against a hydrostatic pressure of 80 cm H2O. During this working period, various indices of cardiac function were measured. The cardiac functions were stable for over 2 hours with perfusion of Krebs-Henseleit solution and autologous blood[1:1] mixture in volume and maintained heart rate ]]3-122/bpm peak systolic pressure 109-113 mmHg, cardiac output 900 ml / min and left atrial mean pressure 8-9 mmHg. In this model, the efficiency of myocardia] protection could be easily measured by means of functional, enzymatic, biochemical and ultrastructural assessment. And also, we believe this model to be a useful assessment screening model of recovery state after long duration of myocardial preservation of donor heart without difficult transplantation procedures.

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A Study on Evaluation of Isolated Rabbit Kidney Function with Computed $^{99m}Tc-DTPA$ Scintigraphy ($^{99m}Tc-DTPA$ Scintigraphy에 의한 분리보존가토신의 기능평가에 관한 연구)

  • Chung, Sun-Il;Ha, Woo-Song
    • The Korean Journal of Nuclear Medicine
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    • v.25 no.1
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    • pp.95-100
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    • 1991
  • Computerized scintigraphv using $^{99m}Tc-DTPA$ was performed to 37 isolated rabbit kidneys after preservation for 48 hours in perfusates differing in their compositions, i. e., Group 1 (N 9) in Collins' solution, Group 2 (N 10) in Collins' plus trifluoperazine, Group 3 (N 9) in Collins' plus urokinase and Group 4 (N 9) in Collins pius urokinase plus verapamil. Satisfactory images, and statistically analyzable quantitative indices such as perfusion score, filtration rate and cortical uptake ratio (CUR) were obtained by the evaluations of first-pass perfusion, equilibration slopes and postequilibration images. Significant improvements in CUR were observed by adding trifluoperazine (Group 2) and urokinase (group 3) as compared to Collins' only group (Group 1), p<0.05 for each, and all of the three indices (perfusion score, filtration rate and CUR) were also significantly (p=0.0092 p<0.05 and p<0.05) improved by adding urokinase plus verapamil (Group 4). We concluded that the computerized scintigraphy with Tc-99m DTPA provide valuable quantitative indices for evaluation of preserved kidney funcitions and suggest its possible clinical applicability in cadaver kidney transplantation considering the safety and easiness of the prodedure.

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Construction of forest environmental information and evaluation of forest environment (산림환경 정보구축 및 산림환경 평가)

  • Chang, Kwan-Soon
    • Journal of Environmental Impact Assessment
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    • v.7 no.2
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    • pp.37-51
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    • 1998
  • This study was carried out to lead the scientific management of the urban forest by estimating the forest environment. Forest environmental information was constructed using IDRISI system based on survey data, soil, plant, and digital elevation data. Forest environmental information was consisted of soil depth, soil organic content, soil hardness and parent rock as a soil environmental factor, and forest community, tree age, crown density as a plant environmental factor. Plant activity and topographic environment also were analyzed by using remote sensing data and digital elevation data. Environmental function of urban forest was estimated based on results of soil conservation and forest productivity. 70% of urban forest is located in elevation of lower than 200m and 55% of forest area have the slope of lower than 15 degree. Analyzed soil conservation status and forest productivity were almost the same as the soil chemical properties of collected soil sample and the vegetation index estimated using remote sensing data, respectively. Thus, the constructed forest environmental information could be useful to give some ideas for management of urban forest ecosystem and establishment of environmental conservation planning, including forests, in Taejon. The best forest environmental function was appeared at the natural ecology preservation zone. Current natural parks and urban parks were appeared to establish the environmental conservation plan for further development. The worst forest environmental function was appeared at the forest near to the industrial area and an overall and systematic plan was required for the soil management and high forest productivity because these forest was developing a severe soil acidification and having a low forest productivity.

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Function and Use Evaluation of 'Classification & Disposal Schedule Management' in the Standard Records Management System (표준 기록관리시스템의 '기준관리' 기능 및 이용 평가)

  • Chung, Sang-hee
    • The Korean Journal of Archival Studies
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    • no.37
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    • pp.189-237
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    • 2013
  • Since central governments began to establish and use the Standard Records Management System(RMS) in 2007, more and more local governments and other public organizations have constructed RMS. RMS is the essential tool for records management in electronic environments, but it is not known how well the functions of RMS reflect standards and practice related records management or how many records managers use RMS in performing their works. This paper deals with analyzing the evaluation of 'classification & disposal schedule management' function in RMS. 'Classification & disposal schedule management' function has 4 subfunctions of review of classification & preservation period, management of the schedule items, assignment of classification scheme and reclassification. Classification and disposal schedule is at the heart of intellectual control of records and core area of records management. So it is important to analyze whether this function plays well a role in RMS or not. This research carried out evaluation of function and use about classification & disposal schedule management in RMS. Functional evaluation is to compare and analyze how well RMS meets the functional requirements which home and foreign standards give. Use evaluation is to investigate how records managers use RMS in accomplishing their task of managing classification & disposal schedule and to look into what is the problem with the use. This paper could get the implications through the survey of records managers who are working at central governments, regional local governments and basic local governments. And these implications are considered in institutional, functional, use and administrative aspect. It is important to communicate with stakeholders so that 'classification & disposal schedule management' function, further, all functions of the RMS in practice of records management could be used smoothly. Users of RMS have to raise demands or call for technical solutions of the problems which come up in use, while RMS developers and administrators must make more of an effort to satisfy their demands, reflect them on the RMS and enhance the system.