• 대한의료기공학회지
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• 제16권1호
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• pp.101-115
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• 2016

Objective : This study investigated the clinical characteristics with Tongdo-san on injured patients focused on traffic accidents cases. Methods : 108 injured patients diagnosed with stagnation of Qi and stagnated blood(氣滯瘀血) were treated with Tongdo-san, acupuncture, cupping, physical therapy, Su-Gi therapy. The degree of Martins AN was checked to observe the change after using Tongdo-san. Results : Evaluation grades of of patients treated with Tongdo-san were all improved. The shorter the period of morbidity and the lower the age, the better the elevation. The degree of elevation is more significant in women traffic accidents patients. Conclusions: According to the study, Tongdo-san might especially effective for women traffic accidents patients with short period of morbidity and lower age.

• Toxicological Research
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• 제32권1호
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• pp.15-20
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• 2016

Physiologically based pharmacokinetic (PBPK) modeling can provide an effective way to utilize in vitro and in silico based information in modern risk assessment for children and other potentially sensitive populations. In this review, we describe the process of in vitro to in vivo extrapolation (IVIVE) to develop PBPK models for a chemical in different ages in order to predict the target tissue exposure at the age of concern in humans. We present our on-going studies on pyrethroids as a proof of concept to guide the readers through the IVIVE steps using the metabolism data collected either from age-specific liver donors or expressed enzymes in conjunction with enzyme ontogeny information to provide age-appropriate metabolism parameters in the PBPK model in the rat and human, respectively. The approach we present here is readily applicable to not just to other pyrethroids, but also to other environmental chemicals and drugs. Establishment of an in vitro and in silico-based evaluation strategy in conjunction with relevant exposure information in humans is of great importance in risk assessment for potentially vulnerable populations like early ages where the necessary information for decision making is limited.

• Journal of Chest Surgery
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• 제28권11호
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• pp.1019-1024
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• 1995

Clinical analysis were performed on 68 cases of subcutaneous emphysema, those were visited at the emergency center of Chosun university hospital during the period form 1992 to 1994. The following result was obtained. 1 The incidence of subcutaneous emphysema was 0.16%, and male was dominant [M:F=6.9:1 .2 The age distribution of subcutaneous emphysema was from 4 to 77 years old and mean age was 49.6$\pm$17.8 years[$\pm$SD 3 The most presenting symptoms were chest pain[49% , and the proceeding cause was traffic accident[38% . 3 The most associated disease was a ipsilateral pneumothorax[59% . 4 Conservative management is an indication in the majority of cases of subcutaneous emphysema because it is usually a self-limited condition and spontaneous remission usually occurs. We conclude that initial effort must be made to detect the underlying cause of the subcutaneous emphysema in order that appropriate management may be undertaken.

• Journal of Chest Surgery
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• 제17권3호
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• pp.511-515
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• 1984

In this study, 213 cases of the spontaneous pneumothorax experienced at the department of thoracic and cardiovascular surgery, Chungnam National University Hospital during from April, 1977, till Dec, 1983 were reviewed. 1.Sex ratio of the studied patients was 7.19;1 showing high incidence male patients. The incidence according to the age group showed that 20.2%, 18.3% of the patients belong to the age group 6th, 5th decade respectively. 2.The etiologic factors were as follows, tuberculous origin in 50.2%, unknown origin in 28.2%, COPD in 3.3%, bullae in 8.5%. The site was right in 47.9% and left in 44.1%, bilateral in 8%. 3.The clinical symptoms were frequently dyspnea in 35%, chest pain in 27.5%. 4.The employed method of treatment were as follow, bed rest with oxygen inhalation in 1.9%, closed thoracostomy in 95.8%, open thoracotomy in 7.98%, which bullectomy was performed in 12 cases and pneumonectomy in 3 cases and lobectomy in 1 case and decortication with simple closure of bleb was performed in remaining 1 case. 5.The duration of closed thoracostomy was longer in tuberculosis, which average duration was 11.28 days. 6.The overall recurrent rate was 12.3%.

• 한국지역사회생활과학회지
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• 제19권2호
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• pp.223-234
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• 2008

This study aimed to develop the elderly care program for seniors in rural areas and to evaluate its efficacy through pre- and post-tests. For them, this study carried out a total of 8 sessions that includes 4 aims, such as understanding rural elderly, volunteer activities, psychological help, and aids to daily living, on 36 persons over the age of 60 years in rural areas. The data was analyzed by paired t-test to 36 elderly. The results of the study are as follows. First, looking at changes in knowledge about aging, objective evaluation of knowledge showed significant differences (t=-2.22, p<.05), but evaluation of elderly's perception-change didn't show significant differences between before and after. Second, volunteer attitude didn't show significant differences between before and after, but after the training, 75% of them answered 'yes' to question that asked whether they'd like to participate in elderly's volunteer caring activity for other elderly within the town in the future, which gave us certain expectation that the attitude towards volunteer activities might change positively in the future. Third, objective evaluation of knowledge for psychological help didn't show significant differences between before and after. But elderly's subjective perception showed significant differences (t=-2.82, p<.01). Fourth, evaluating changes in knowledge for elderly's aiding daily life, both the objective evaluation and subjective evaluation didn't show significant differences between before and after. Fifth, satisfaction of the program showed high scores over 4 points: contents, education methods, education place, education time. The most helpful topics for them were counseling (27.8%) and dementia (27.8%), followed by elderly and aging (16.7%), elderly's residential environment (13.9%), elderly's dietary life (9.3%) and volunteer activities (5.6%).

• Journal of Chest Surgery
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• 제23권2호
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• pp.236-244
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• 1990

To improve the prognosis of mitral valve replacement surgery, analysis and evaluation of pre and intra operative risk factors will be very much valuable. Author studied 205 cases of mitral valve replacement from Feb 1982 to June 1989 for the risk factors of hospital death. 90 patients were male and 115 were female, and age was from 16 to 59 years, Mitral stenosis dominant lesions were 91 cases and regurgitation 114. Suspected risk factors were NYHA functional class, cardiothoracic ratio, implanted valve type and size, operation time, age and sex, thrombus in left atrium, atrial fibrillation, aortic cross clamping time, left ventricular end diastolic and systolic dimension, nephropathy, hepatopathy and respiratory insufficiency. Statistic analysis was performed by X2 test between survivors and death group. Statistical significances as pre and intraoperative risk factors of hospital death after mitral valve replacement were confirmed in those presence of AF on the EKG, NYHA functional class[>IV], cardiothoracic ratio[>70%], and implanted valve size[>33mm]

• Journal of Chest Surgery
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• 제28권2호
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• pp.150-155
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• 1995

For study the influencing factors to the complication after pneumonectomy, authors performed retrospective analysis in 33 patients managed surgically from February 1985 to February 1994 in the Department of Thoracic and Cardiovascular Surgery, Pusan National University Hospital.Among 33 patients, the underlying diseases were distributed 15 patients[45.5% pulmonary tuberculosis, 14[42.% lung cancer and 4[12.1% bronchiectasis. Numbers of complication according to the underlying disease after pneumonectomy were 8 in pulmonary tuberculosis, 2 in lung cancer and 1 in brochiectasis. Study was analyzed on age, sex distribution, etiology of underlying diseases and operated sides contributing to the complication. The results were characterized that the rate of occurrence of complication after pneumonectomy was not affected by age, sex and operated side differences but affected by the underlying disease.The development of complication after pneumonectomy in patients with pulmonary tuberculosis revealed statistically borderline significance comparing to the others[p=0.07 .

• 한국건축시공학회:학술대회논문집
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• 한국건축시공학회 2016년도 추계 학술논문 발표대회
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• pp.152-153
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• 2016

In this research, we evaluate the performance for preventing frost damage at early age of mortar using variable cement and self-heating binder. Purpose of final research is preventing freezing and thawing by making the compressive strength 5MPa in 3days below zero temperature without heat curing. We compare the compressive strength of mortar and concrete using variable cements and self-heating binder in low temperature.

• Journal of Chest Surgery
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• 제26권10호
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• pp.791-797
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• 1993

We evaluated forty cases of traumatic diaphragmatic ruptures that we have experienced from Mar. 1976 to Mar. 1992. Thirty patients were male and 10 were female[M:F=3:1]. The age distribution was ranged from 2 to 76 years with the mean age of 35 years. The traumatic diaphragmatic ruptures were due to blunt trauma in 26 cases[traffic accident 20, fall down 4, others 2] and penetrating trauma in 14 cases[stab wound 13, gun shot 1]. In the blunt trauma, 21 of 26 cases were diagnosed within 24 hours after injury and all cases except one in penetrating trauma were diagnosed within 24 hours. In the blunt trauma, the rupture site was located in the left in 20 cases and in the right in 6 cases. In the penetrating trauma, the rupture site was located in the left in 10 cases and in the right in 4 cases. The repair of 40 cases were performed with thoracic approach in 19 cases, thoracoabdominal approach in 17 cases and abdominal approach in 4 cases. The postoperative mortality was 7.5 %[3/40]. The causes of death were septic shock[1], acute renal failure[1] and hypovolemic shock[1].

• 한국건축시공학회:학술대회논문집
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• 한국건축시공학회 2021년도 봄 학술논문 발표대회
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• pp.231-232
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• 2021

This study intended to verify the alkali activation effect of concrete by replacing FA and CBS-Dust with cement to find out how to utilize CBS-Dust generated during cement production. Experiments result shows that air flow and liquidity can be secured when CBS-Dust is replaced by 5% in FA 20%, and that relatively high compressive strength is expressed in the initial age of 3 days and 7 days and long-term age of 91 days.