Dobran, Mauro;Marini, Alessandra;Nasi, Davide;Liverotti, Valentina;Benigni, Roberta;Costanza, Martina Della;Mancini, Fabrizio;Scerrati, Massimo
Journal of Korean Neurosurgical Society
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제65권1호
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pp.123-129
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2022
Objective : Chronic subdural hematoma (CSDH) is one of the most common pathology in daily neurosurgical practice and incidence increases with age. The aim of this study was to evaluate the prognostic factors and surgical outcome of CSDH in patients aging over 90 years compared with a control group of patients aging under 90 years. Methods : This study reviewed 25 patients with CSDH aged over 90 years of age treated in our department. This group was compared with a younger group of 25 patients aged below their eighties. At admission past medical history was recorded concerning comorbidities (hypertension, dementia, ictus cerebri, diabetes, and heart failure or attack). History of alcohol abuse, anticoagulant and antiplatelet therapy, head trauma and seizures were analyzed. Standard neurological examination and Markwalder score at admission, 48 hours after surgery and 1-6 months follow-up, radiologic data including location and CSDH maximum thickness were also evaluated. Results : Their mean age was 92.8 years and the median was 92.4 years (range, 90-100 years). In older group, the Markwalder evaluation at one month documented the complete recovery of 24 patients out of 25 without statistical difference with the younger group. This data was confirmed at 6-month follow-up. One patient died from cardiovascular failure 20 days after surgery. The presence of comorbidities, risk factors (antiplatelet therapy, anticoagulant therapy, history of alcohol abuse, and head trauma), preoperative symptoms, mono or bilateral CSDH, maximum thickness of hematoma, surgical time and recurrence were similar and statistically not significant in both groups. Conclusion : In this study, we demonstrate that surgery for very old patients above 90 years of age affected by CSDH is safe and allows complete recovery. Comparing two groups of patients above and under 90 years old we found that complication rate and recovery were similar in both groups.
Objective : This study is to provide the norms of normal children when comparing the performance ability of preschool children while using the kinesthesia test of Sensory Integration and Praxis Tests(SIPT). Methods : Participants consisted of 90 normal children ranging in age from four to six years. The kinesthesia test of SIPT was utilized to investigate the performance ability. Results : 1. Regarding the kinesthesia ability according to age, the average value of kinesthesia performance error decreased as age getting older and that value showed the statistically significant differences between four and five, six age(p<0.05). 2. The kinesthesia performance ability according to gender, the accuracy of both hands and the dominant hand did not show the statistically significant differences. 3. Regarding the kinesthesia performance ability of test items, 1R item and 6R item(26.2cm), 5R item and 2L item(20.2cm) passing through the midline of body and having the large movement in distance and angle showed the difficulty to perform in all the children between 4 and 6 age. Conclusion : By providing the norms of the kinesthesia performance ability in normal children of the above results to the occupational therapists treating children, the helpful data to the hand skill development of children, exercise plan and implementation, and the performance therapy of ADL through the proper evaluation and training of kinesthesia is considered for the occupational therapists to be provided.
Purpose: The aim of this study was to determine whether the panoramic mandibular index (PMI) is useful for assessing bone mineral density. We also analyzed the potential correlations between PMI parameters and patient age. Materials and Methods: Four observers measured the PMI of both sides of the mental foramen using a picture archiving and communication system and images in the Digital Imaging and Communications in Medicine format. They studied 300 panoramic radiographic images of patients belonging to the following age groups: 40-49 years, 50-59 years, 60-69 years, 70-79 years, and 80-89 years. The observers were allowed to zoom in or out and to adjust the contrast of the images. Further, they were instructed to record the reasons for any measurements that could not be made. Then, we conducted a reliability analysis of the measured PMI and assessed the correlations between different patient age groups and the 3 parameters used for determining the PMI from the available data. Results: Among the 600 data items collected, 23 items were considered unmeasurable by at least 1 observer for the following 4 reasons: postoperative state, lesion, unidentified mental foramen, and alveolar bone loss. The intraobserver reproducibility of the measurable data was 0.611-0.752. The mandibular cortical width (MCW) decreased significantly as patient age increased. Conclusion: PMI had limited usability when the margin of the mental foramen was not clear. In contrast, MCW, a parameter used for determining the PMI, had fewer drawbacks than the PMI with respect to bone mineral density measurements and exhibited a significant correlation with patient age.
Background and Purpose : Cerebrovascular reactivity(CVR) can be estimated by measuring the change of cerebral blood flow that occurs during vasostimulation. To estimate the cerebrovascular reactivity, we investigated the change of flow velocity of the middle cerebral artery(MCA) during hyperventilation and hypoventilation with the transcranial doppler. So we studied whether the CVR measured by this method could show a significant difference between the normal and the cerebral infarction subjects and whether the CVR may decrease with age in normal subjects. Methods : Using transcranial doppler, we measured the mean velocity(Vm), the pulsatility index(P.I.) at the resting state, the end of breath-holding and the end of hyperventilation in 36 normal and 10 cerebral infarction subjects, so we calculated the percentile change of mean velocity(%${\Delta}$Vm) and P.I.(%${\Delta}$P.I.) after the vasostimulation. We estimated the change of Vm, P.I., %${\Delta}$Vm and %${\Delta}$P.I. by the age group and compared those parameters between the age-matched normal control and cerebral infarction subjects. Results : The Vm in MCA significantly decreased with age(p<0.05), but there was no significant difference in Vm and P.I. between normal and cerebral infarction subjects. The %${\Delta}$Vm and %${\Delta}$P.I. in response to hyperventilation significantly decreased with age in MCA and there was significant difference in $%{\Delta}Vm$ of MCA after breath-holding between the normal and cerebral infarction subjects. Conclusion : The breath-holding and hyperventilation tests could be non-invasive and useful methods in estimation of the cerebrovascular reactivity and could be applied in the basal and follow-up evaluation of the cerebrovascular reserve of the ischemic stroke patients.
Controlled Low Strength Material (CLSM) has high fluidity and self-compaction characteristics. CLSM is mainly used for backfilling the excavated road. Early-age properties of CLSM should be characterized for fast restoration of the road. In this study, shear wave monitoring and Vicat needle test are performed to investigate the early-age properties of CLSM depending on the setting time. CLSM consists of CSA cement, fly ash, silt and sand, accelerator, and water. Five fly ashes with different chemical properties are used for CLSM samples. The penetration of CLSM along setting time is obtained through the Vicat needle test. A pair of bender elements are placed in a mold for shear wave measurement, and the change in shear waves with the setting time is monitored. The experimental results show that, regardless of the type of fly ash, the penetration depth decreases and the shear wave velocity increases with the setting time. Depending on the type of fly ash, initial and final times and shear wave velocity change. After testing, the correlation between penetration and shear wave velocity is obtained with high coefficient of determination. The shear wave measurement technique using the bender element can be used to identify early-age properties.
Objective: This study aimed to evaluate the zygomaticotemporal suture (ZTS) maturation, analyze the age distribution patterns of ZTS maturation stages, and investigate the relationship between ZTS and cervical vertebral maturation (CVM). Methods: A total of 261 patients who underwent cone-beam computed tomography (112 males, mean age, 13.1 ± 3.3 years; 149 females, mean age, 13.7 ± 3.1 years) were examined to evaluate the ZTS stages. The ZTS stages were defined based on a modified method from previous studies on zygomaticomaxillary sutures. Differences between groups and correlations between indicators were analyzed using the Spearman correlation test, intraclass coefficient of correlation (ICC), one-way analysis of variance and rank sum test. Statistical significance was set at p < 0.05. The diagnostic value of CVM stages in identifying ZTS maturation stages was evaluated using positive likelihood ratios (LRs). Results: A positive relationship was found between the ZTS and CVM stage (r = 0.747, ICC = 0.621, p < 0.01) and between the ZTS stage and chronological age (r = 0.727, ICC = 0.330, p < 0.01). Positive LRs > 10 were found for several cervical stages (CSs), including CS1 and CS2 for the diagnosis of stage B, CS1 to CS3 for the diagnosis of stages B and C, and CS6 for the diagnosis of stages D and E. Conclusions: The ZTS maturation stage may be more relevant to the CVM stage than to the chronological age. The CVM stages can be good indicators for clinical decisions regarding maxillary protraction, except for CS4 and CS5.
Kim, Min-Jae;Kang, Soo-Kyung;Chun, Yang-Hyun;Hong, Jung-Pyo;Auh, Q-Schick
Journal of Oral Medicine and Pain
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제39권2호
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pp.63-68
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2014
Purpose: This study was designed to evaluate the sex and age differences in the Korean oral malodor patients. Methods: Subjects were the patients with oral malodor (male, 2,239; female, 3,496) visited the Department of Oral Medicine, Kyung Hee University Dental Hospital from January 2007 to December 2012 were recruited to this study and measured the volatile sulfur compounds (VSCs) in the oral cavity with Halimeter. Results: There were slightly more female than male (female : male=3 : 2), and the mean values of Halimeter result were 65.79 ppb (female) and 79.94 ppb (male), which was more higher in male. Total patients showed normal age distribution in both gender, and the peak was the age of 26-35 in female, the age of 36-45 in male. The percentages of pseudo-halitosis were 74.7% in female and 69.3% in male, which was more higher in female. Conclusions: Therefore, it was revealed that women are more likely to have oral malodor than men, and there was a difference in the largest age group between men and women. Also women had more pseudo-halitosis patient than men.
Objective : The purpose of this study was to investigate the correlation between hand dexterity and visual-motor skills of preschoolers. We searched for the correlation between two test results, which were the 9-Hole Peg Test performance time and the visual motor integration test(VMI) performance score. Then, we also compared the 9-Hole Peg Test performance times with the VMI performance scores according to sex and age. Method : The participants were fifty normal children ranging in age from four to six years living in Busan. We used two test methods which have high reliability and validity. One was the 9-Hole Peg Test to evaluate hand dexterity, and the other was the VMI to the evaluate visual-motor skills of these young children. Results : First, over the entire range of the participating children, there was a high correlation between the performance times from the 9-Hole Peg Test and the VMI performance scores(r=-.682). Second, there was not a statistically significant difference between the performance times from the 9-Hole Peg Test and the VMI scores according to sex. Third, there were significant differences between the hand dexterity and visual-motor skills according to the children's age(p<.001). Conclusion : This study proved that there is high correlation between hand dexterity and visual-motor skills of the preschooler. Occupational therapists in preschool service should consider that visual-motor skills need to be compatible with hand dexterity in both evaluation and therapy. In addition, hand dexterity and visual-motor skills improved according to advances in age, so we must give graded tasks to proper age groups through concrete analysis of activity. By doing this, children can get the better therapeutic effects.
Introduction: Breast cancer is the most common malignancy of women in Kashmir. This study was conducted with the objective of assessing hormone receptor positivity and its correlation with age at diagnosis, tumor size, histological grade and lymph node metastasis. Materials and Methods: 132 newly diagnosed cases of invasive breast cancer diagnosed at the Department of Pathology, SKIMS, Srinagar, J&K, were included after excluding biopsies, in-situ lesions and recurrence cases. Results: Mean age of the patients was 48.2 years, 59.1% being ${\leq}50$ years of age. Mean duration of symptoms was 6.32 months. Most lesions (65.1%) were 2-5 cm and 16.7% were ${\geq}5.0$ cm in greatest dimension. The predominant (80.3%) morphology was IDC-NOS. The majority of the cases presented as grade II (52.1%) lesions and lymph node involvement was present in 65.2%. ER and PR were positive in 66.3% and 63.4% cases, respectively, increasing with rising age. High grade lesions and larger size tumors were more likely to be ER and PR negative. No correlation was found between ER/PR status and lymph node metastasis. Conclusions: ER and PR expression in breast cancers in the current study was found to be higher than studies done in India/Asia but lower than studies conducted in the West, even on Indian/Asian immigrants. Markedly lower receptor expression in Indian/Asian studies is likely due to preanalytic variables, thresholds for positivity, and interpretation criteria. American Society of Clinical Oncology/College of American Pathologists Guideline Recommendations for Immunohistochemical Testing of Estrogen and Progesterone Receptors in Breast Cancer are strongly advocated for standardization of receptor evaluation and for clinical management of breast cancer patients to provide best therapeutic options.
Bye-Ri Han;Mi-Yeon Kim;Sun-Ho Kim;Jeong-Hee Kim;Ran-Ah Kim
Journal of Korean Dental Science
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제16권2호
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pp.192-203
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2023
Purpose: This study is to investigate the distribution of natural tooth shades in the Korean elderly population to quantify the correlation and changes of tooth color with age and gender. In addition, the possible effects of habits on tooth color were assessed. Materials and Methods: The tooth color of one of the maxillary central incisors of 200 Korean individuals aged 50 to 89 years, males and female, was measured using the portable intraoral spectrophotometer (VITA Easyshade V). CIELab and CIELCh color coordinates were recorded. We conducted the survey about the tobacco smoking, chronic disease, medication, eating habits, oral health behaviors and satisfaction with tooth color. Experimental data were statistically analyzed by using the t-test (P<0.05), two-way analysis of variance and Pearson's correlation test. Result: The most frequent color in the Korean elderly population was 3M3 & A3.5 shade. L* and h* values decreased, whereas C*, a* and b* values increased progressively with age. There was a significant interaction between age and color coordinates for b* values (r=0.245, P<0.05). Males generally have significantly higher C*, a*, b* values and lower L*, h* value compared to females. Individuals who consumed alcohol had a higher L* value (P<0.05). Conclusion: Within the limitation of this study, the central incisors were getting darker, more reddish, and yellowish with age. Information on the chromatic range of natural teeth by age and gender could help to select colors for esthetic dental restorations.
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