• Title/Summary/Keyword: evaluation of age

Search Result 3,331, Processing Time 0.03 seconds

Rhamnose-rich and fucose-rich oligo- and polysaccharides (RROP-s and FROPs), agonists and antagonists of cell-membrane receptors as new active principles against skin aging.

  • Robert, L.;Robert, A.M.;Gesztes, J.L.;Luppi, E.
    • Proceedings of the SCSK Conference
    • /
    • 2003.09a
    • /
    • pp.352-373
    • /
    • 2003
  • Rhamnose-rich (RROP-s) and fucose-rich (FROP-s) oligo-and polysaccharides were prepared and extensively characterised by physical and chemical procedures [1,2] and compared to L-fucose. Their biological properties were then studied on human skin fibroblast cell cultures, human skin explant cultures and on hairless rat skin, using a variety of cell-biological, biochemical and computerised morphometrical procedures. Among the most important properties we could establish, the following are of particular interest for the tretment and prevention of age-dependent modifications of human skin (loss of skin-tissue, cells and matrix, wrinkle formation and others) : stimulation of cell proliferation (by $^3$[H]-thymidine incorporation and the MTT test), scavenging of reactive oxygen species (ROS) using several different procedures, and protease (MMP-2 and MMP-9) down-regulation. A topical preparation, using RROP-s and FROP-s, and/or L-fucose, was shown to increase cell proliferation, dermal matrix synthesis, efficient scavenging of ROS-s and to increase also the thickness of dermal tissue when applied for 4 weeks on hairless rat skin, accompanied by the densification of collagen bundles as well as by an increase of elastin synthesis. Using fluorescent labeled FROPs, it could be shown that these oligosaccharides react with cell-membrane receptors and especially with the elastin-laminin-receptor and the fucose-mannose receptor, but they penetrate also in the cell nucleus, suggesting the possibility of a direct action on the regulation of gene expression. When applied to the human skin of a team of voluntary women encompassing all age-groups, the efficiency of FROP-containing preparation could be confirmed using indentometry and computerised evaluation of skin micro-relief, as well as evaluation of periorbital wrinkles. It appears therefore that these preparations correspond to all the requirements of active anti-aging principles.

  • PDF

A Study on Subjective Nise Evaluation of Rdesidential Area on Aircraft Noise near Airport - Case Study on Taegu Airport - (공항 인근주민들의 항공기소음에 대한 피해의식 구조에 관한 연구 - 대구공항을 사례지역으로 -)

  • 김재석
    • Journal of KSNVE
    • /
    • v.10 no.1
    • /
    • pp.41-48
    • /
    • 2000
  • Evaluation model for damage consciousness was established through the survey of 2,210 residents' consciousness on aircraft noise near Taegu Airport. There were none who replied that the level of the aircraft noise was as los as it was quiet. 77(3.5%) people replied the noise was normal, and 2,133(95.5%) people said it was noisy. As to the period of time when the aircraft noise occurred, 51%, 97%, 86%, 0.6% of the residents pointed out the morning time, the day time, the evening time, and the night time, respectively. Because of aircraft noise, 73%, 88%, 70%, 77%, 78%, and 33% of the residents felt it disturbing indoor conversation, telephoning, watching TV or listening to the ratio, reading or meditating, working, sleeping, and studying, respectively. It was examined that the bad effects of aircraft noise on the health were severe : 43% of the resident said they experienced embarrassment. 52% astonishment, 66% absence of mind, 61% heart-beating. 77% headaches, 78% earache, and 93% displeasure. For the survey of the residents' damage consciousness about aircraft noise, the level of aircraft noise was set as an objective variable, and gender, age, occupation. Education, the type of house, the structure of windows, the consciousness of settlement in the district, and the period of residence were set as explanatory variables. And the quantification theory I was applied to the analysis. The most influencing factor of the damage consciousness on aircraft noise was the education, the second occupation, the third age, the forth the consciousness of settlement, the fifth the period of residence, the sixth gender, the seventh the type of house, and the least influencing factor among them was the structure of windows. These findings will be a useful guideline when the government seeks to set up policies which will help solve the resident's noise problems near Taegu Airport.

  • PDF

Assessment of bifid and trifid mandibular canals using cone-beam computed tomography

  • Rashsuren, Oyuntugs;Choi, Jin-Woo;Han, Won-Jeong;Kim, Eun-Kyung
    • Imaging Science in Dentistry
    • /
    • v.44 no.3
    • /
    • pp.229-236
    • /
    • 2014
  • Purpose: To investigate the prevalence of bifid and trifid mandibular canals using cone-beam computed tomography (CBCT) images, and to measure their length, diameter, and angle. Materials and Methods: CBCT images of 500 patients, involving 755 hemi-mandibles, were used for this study. The presence and type of bifid mandibular canal was evaluated according to a modified classification of Naitoh et al. Prevalence rates were determined according to age group, gender, and type. Further, their diameter, length, and angles were measured using PACSPLUS Viewer and ImageJ 1.46r. Statistical analysis with chi-squared and analysis of variance (ANOVA) tests was performed. Results: Bifid and trifid mandibular canals were found in 22.6% of the 500 patients and 16.2% of the 755 sides. There was no significant difference between genders and among age groups. The retromolar canal type accounted for 71.3% of the identified canals; the dental canal type, 18.8%; the forward canal type, 4.1%; and the trifid canal type, 5.8%. Interestingly, seven cases of the trifid canal type, which has been rarely reported, were observed. The mean diameter of the bifid and trifid mandibular canals was 2.2 mm and that of the main mandibular canal was 4.3 mm. Their mean length was 16.9 mm; the mean superior angle was $149.2^{\circ}$, and the mean inferior angle was $37.7^{\circ}$. Conclusion: Bifid and trifid mandibular canals in the Korean population were observed at a relatively high rate through a CBCT evaluation, and the most common type was the retromolar canal. CBCT is suggested for a detailed evaluation of bifid and trifid mandibular canals before mandibular surgery.

Comparative Analysis of National Policies for Open Data Government Ecosystem (공공데이터 생태계 조성을 위한 주요 국가별 정책에 관한 비교 분석)

  • Song, Seokhyun;Lee, Jai Yong
    • Journal of Korean Society of Industrial and Systems Engineering
    • /
    • v.41 no.1
    • /
    • pp.128-139
    • /
    • 2018
  • As The Fourth Industrial Revolution and Intelligent Information Age came into full-scale, the policy of open government data has become a hot topic for each country. The United States, the United Kingdom, and other countries are shifting policy direction to "creating value" of open government data. Also, in the age of the digital economy where the data market is soaring, open government data is gradually being recognized as a new raw material for new business and start-ups. In addition, Korea ranked first in the OECD open government data evaluation twice in a row, and was highly evaluated in the international evaluation. However, domestic firms are still lacking in qualitative openness of government data, data is dispersed among institutions, lack of public-private data linkage, and development of app-oriented development. This study attempts to analyze major national policies for the creation of a data ecosystem that considers data lifecycle, from production to storage, distribution and utilization of data. First, the target countries were the leading public data countries among the OGP member countries, the USA, the UK, Australia and Canada. The results of this study are as follows. As a result of analyzing the results and comparing Korea's policies, it was concluded that most of Korea is superior in open government data policy. However, improvement of data quality, development of open data portal as an open platform, support for finding various users including apps and web development companies, and cultivation of open government data utilizing personnel are analyzed as policy issues. In addition, the direction of policy for the balanced ecosystem of Korea is presented together.

Open reduction of mandibular fracture without maxillomandibular fixation: retrospective study (악간고정 없는 하악골 골절의 관혈적 정복술: 후향적 연구)

  • Lee, Chung-Hyun;Kim, Chul-Hwan
    • Journal of the Korean Association of Oral and Maxillofacial Surgeons
    • /
    • v.37 no.4
    • /
    • pp.255-263
    • /
    • 2011
  • Introduction: Maxillomandibular fixation (MMF) is essential before surgery under general anesthesia in maxillofacial trauma patients. MMF is used basically to reconstruct the occlusion and occlusal stability to recover the facial shape and oral functions. The arch bar and wire is a traditional method for MMF, but it can not only bring pressure to the periodontal ligaments and teeth but also cause a penetrating injury to the surgeons. Materials and Methods: In this study, 198 patients with an open reduction using a manual reduction without MMF from September 2005 to May 2010 in Dankook University Dental Hospital were subjected to a follow-up evaluation during the postoperative 4 months periods. This study evaluated the incidence of complications according to the condition of the patient (gender, age), the state of bony union of the fracture sites and a numeric rating scale evaluation for postoperative pain scoring. Results: 1. The complications were classified into major and minor according to the seriousness, and the major complication rate was as low as 2.02%. Only 2 cases of re-operations (1.01%) were encountered. In the classification according to the fracture line, plate fracture was observed in both cases of mandibular symphysis fracture, and angle fractures and loosening of two screws were noted in the case of mandibular angle fracture. 2. The complication rate was similar regardless of gender and age. 3. The degree of bony union was satisfactory, and the complication rate was reduced as the bony union improved. 4. More patients complained of pain as the operation time was increased. Conclusion: The use of MMF is not always necessary if a skilled assistant is provided to help manually reduce the fracture site. Compared to other studies of mandibular fracture surgery using MMF, the complication rate was similar using only manual reduction and the patients' discomfort was reduced without MMF.

The Needs of a Parent Education Program for the Prevention of Home Injury (가정내 안전사고 예방을 위한 부모교육 프로그램 요구)

  • Kim, Hye-Gum
    • Journal of the Korean Home Economics Association
    • /
    • v.44 no.1 s.215
    • /
    • pp.87-99
    • /
    • 2006
  • This study investigated the degree to which young children's mothers needed a parent education program on home safety, the preferred goals, contents, methods, and evaluation of a parent education program on home safety, and whether or not the needs for a parent education program on home safety varied according to mothers' age, education background, and job. This study also analyzed the experience of their participation in any parent education program on home safety and its effect according to mothers' age, education background, and job. The data were collected from 569 mothers of young children and analyzed by $X^2$ and F tests. A questionnaire was developed based on the research of Peterson and Mori (1985) and Jung et al. (1992). The conclusions of this study were as follows: 1. The majority (92.8%) of mothers recognized the need for a parent education program on home safety and 97.5% indicated an intention of participating in a parent education program on home safety. 2. Mothers rated the most important goal of a parent education program on home safety as protecting young children from injuries. Mothers in their 30's responded to the need for understanding of young children's development characteristics and safety guidance as the highest while mothers in their 20's responded methods of first aid the highest. 3. The preferred methods of a parent education program on home safety were activities or learning by experience and the preferred instructors were safety professionals majoring in child development and family studies or early childhood education. The preferred practice methods of a parent education program on home safety were 5 sessions, with 25-29 participants, at young children's institute, on weekday afternoons, for one and a half hours per session, and with evaluation through questionnaire. 4. Nearly half (44%) of mothers had participated in a parent education program on home safety during the previous 3 years and 77.6% of them responded that a parent education program on home safety was effective on their safety lives. Mothers in their 30's had more experiences of a parent education program for home safety more than mothers in their 20's.

Sacral Ratio In Normal Children And Patients With Anorectal Malformations (소아 및 항문직장기형 환자의 천골비)

  • Oh, Jung-Tak;Kim, Hee-Jin;Son, Suk-Woo;Han, Ai-Ri;Han, Seok-Joo;Choi, Seung-Hoon;Hwang, Eui-Ho
    • Advances in pediatric surgery
    • /
    • v.6 no.1
    • /
    • pp.32-39
    • /
    • 2000
  • Evaluation of the sacrum in anorectal malformations (ARMs) is important because there is an association between sacral abnormalities and poor functional outcome after corrective surgery for ARM. Sacral defects are not easily detected because of immaturity of sacrum in children and defects are often overlooked by pediatric surgeons. The authors utilized the sacral ratio in normal children (N=61) and patients with ARMs (N=26). In normal children, the mean true sacral ratio and mean sacrococcygeal ratio were $0.60{\pm}0.08$ and $0.72{\pm}0.13$ respectively. The sacral ratio was not correlated with age and did not changed with age in the same patient. However, true sacral ratio and sacrococcygeal ratio were significantly lower in patients with high type ARMs than those of normal children (p<0.001). There was no difference between patients with low type ARMs and normal children. These results suggest that abnormal sacrums are more frequently encountered in patients with high type ARMs than in normal children, and that true sacral ratio and sacrococcygeal ratio can be used in the evaluation of the abnormal sacrum.

  • PDF

A suggestion of Aortic wall Stiffness Evaluation Technique Independent on Changeable Blood Pressure : Aortic Distensibility Index (변화하는 혈압의 영향을 받지 않는 동맥 벽의 강화도 측정 방법 제안 : 대동맥 확장지수)

  • Seo, Jee-Hye;Choi, Dong-Ho;Wu, Zhuqing;Rienmueller, Rainer;Lee, Jong-Min
    • Journal of Biomedical Engineering Research
    • /
    • v.29 no.2
    • /
    • pp.151-158
    • /
    • 2008
  • To evaluate aortic wall stiffness without influence of different background blood pressure, a new technique was developed and verified. At eight swine descending aortae, volume-pressure measurement was performed using custom-made system. Based on averaged pressure-volume curve, aortic distensibility index was formulated to evaluate aortic wall stiffness regardless of variable blood pressure and aortic size. The variability of aortic distensibility index by pressure change was compared with other parameters for wall stiffness evaluation. Subsequently, the aortic distensibility index was calculated at 100 contrast-enhanced EBCT data sets of normal volunteers in regular health screening program. The measured aortic distensibility index was compared with age, coronary calcium score, and aortic calcium score. Between 50 and 360 mmHg of blood pressure, the coefficient of variance of aortic distensibility index was 22.00% as comparing with 88.99% of classical compliance. Based on age, aortic distensibility index showed correlation coefficient of 0.55, whereas classical compliance showed 0.26. The correlation coefficient with modified aortic calcification was 0.43. Linear regression study revealed statistical significance of correlation coefficients. The aortic distensibility index, the method to evaluate aortic wall stiffness free from variable blood pressure and aortic size, was developed and verified with significant practical feasibility.

Revaluation of Reflux Finding Score(RFS) in Laryngopharyngeal Reflux(LPR) (인후두역류증의 진단에 있어서 후두내시경검사 소견 점수화의 유용성에 대한 재검증)

  • Kwon, Kee-Hwan;Ban, Jae-Ho;Lee, Kyung-Chul
    • Journal of the Korean Society of Laryngology, Phoniatrics and Logopedics
    • /
    • v.15 no.2
    • /
    • pp.81-86
    • /
    • 2004
  • Background and Objectives : In general, ambulatory 24-hour pH monitoring is considered the current gold standard for larynogopharyngeal reflux(LPR). There is no validated instrument whose purpose is to document the physical finding and severity of laryngopharyngeal reflux. The purposes of this study are to revaluate the validity and reliability of the reflux finding score(RFS) and to quantify laryngoscopic findings using reflux finding score. Material and Methods : Thirty-three LPR patients confirmed by dual-probe pH monitoring and thirty patients of control were selected. The RFS was documented for each patient with telescopic laryngoscopy before treatment. For test-retest intraobserver reliability assessment, a blinded laryngologists determined the RFS on two separate occasions. To evaluate interobserver reliability assessment, the RFS was determined by t재 different blinded laryngologists. Results : The mean age of the cohort with pH-documented LPR was 45.8 years and the mean RFS was 11.4. The mean age of cotrol subjects was 52 years and the mean RFS was 5.4. The mean RFS for laryngologist no. 1 was 10.8 at the initial screening and 10.9 at the repeat evaluation. The mean FRS for laryngologist no.2 was 11.1 at the intial test and 10.9 at the repeat evaluation. The correlation coefficient for interobserver variability was 0.93 and intraobserver variability was 0.94. Conclusion : The RFS demonstrates excellent inter-and introaobserver reproducibility and is helpful for quantifying laryngeal finding in LPR. We can be 95% certain that an individual with a RFS greater than 7 has LPR.

  • PDF

Soy food intake behavior by socio-demographic characteristics of Korean housewives

  • Lee, Min-June;Park, Ok-Jin
    • Nutrition Research and Practice
    • /
    • v.2 no.4
    • /
    • pp.275-282
    • /
    • 2008
  • In this study, the soy food intake behaviors including perception and intake frequency of soybean foods by sociodemographic variables were analyzed in housewives. The perception of housewives for soy foods showed that soybean paste, soybean curd, and Dambuk were high in the descending order for nutritional quality and health promotion effect, and soybean paste received the highest score in taste and flavor. Soybean sprouts received the highest evaluation score in the economic aspect. In the aspect of safe food, soybean paste received the highest evaluation score, as mush as a traditional food. The analysis of perception by sociodemographic variables showed that soybean curd, Dambuk, and soybean sprouts had higher perceptions as education level increased, and soy milk had higher perceptions in subjects with younger age and with employment. In the intake frequency, more than 50% of the subjects had soybean curd, soybean sprouts, and soybean paste more than once a week. The analysis for correlation between the intake frequency of soy foods and the degree of perception showed that taste and flavor had high correlation with the intake frequency of soy foods except soybean sprouts. The intake frequency of soybean paste, Dambuk, and soy milk had positive correlations to familiarity and that of soy milk had positive correlations to nutrition and health perception, and those of soybeam paste, soybean sprouts, and soy milk had positive correlations to safe food perception. From the above results, housewives in Korea had very high perceptions to nutritional quality and health promotion effect of soy foods and the degree of perception and accompanied intake frequency had significant differences by age, education level, and economic level among sociodemographic variables.