• 한국자연치유학회지
• /
• 제11권2호
• /
• pp.136-142
• /
• 2022

배경: 본 연구는 1970년 때부터 현재까지 우리나라의 기생충 감염률의 변화와 관리에 대한 고찰은 자연치유적 관점에서도 필요하다고 본다. 목적: 연구 목적은 감염률이 어떠한 방법에 따라서 감소율의 변화가 현재까지 진행되었는지를 고찰해보는 것이었다. 방법: 문헌 조사를 하였다. 결과: 우리나라는 1970년대까지는 기생충 감염률이 가장 높은 국가 중 하나였다. 감염률을 관리하기 위하여 1966년에는 기생충병 예방법을 제정하였고, 1969년부터 전국적인 기생충 관리 국가사업을 전체 학생을 대상으로 1년에 2회 전체 기생충 충란 양성자에 대한 치료를 1995년까지 수행하였다. 정부는 한국기생충박멸협회에 위탁하여 구충 박멸사업을 2년 간격으로 1971년~2012년까지 8차례를 전국 기생충감염 실태조사를 하였다. 그 결과로 1971년에는 전체 기생충 충란 양성률이 84.3%이었으나 2012년에는 2.6%로 감소하였다. 회충, 폐흡충, 조충 및 장내 원충류는 전국적으로 매우 감소하였다. 결론: 우리나라에서의 성공적인 기생충 관리는 국가적 경제성장력의 증진과 동시에 기생충박멸에 대한 사회적 합의와 개선된 전문적인 기생충 예방지침과 유효한 구충제 공급 등이 체계적으로 관리하여 성공적인 효과를 이루었다고 판단한다. 그리고 자연치유적 관점에서도 중요하다고 생각한다.

• 한국환경보건학회지
• /
• 제3권1호
• /
• pp.22-26
• /
• 1976

Korea Parasite Eradication Association alleged in its seasonal spring report in 1975 that 36.8 percent of primary, middle and high school students in Seoul area are infected with parasites. Such a high rate of infection is a result of having used raw excrement for manure. Soil is, therefore, to a large extent infected with parasite eggs. In order to present helpful reference materials for preventing parasite infection in the area where human feces have been used for manure, soil in Seoul area and the suburban districts is sampled at random and then the rate of infection in various areas and the variation of infection rate in the same area are studied. The results are as follows 1) The parasite infection rates the according to districts are, Sootaik-ri 39.9%, Chamsil-dong14.2%, Songpa-dong 13.2%, Sageun-dong 12.8% Chayang-dong 11.4%, Sungsoo-dong 8.5%. The above figures show that the rate becomes higher as the area is farther from the urban and residential districts and nearer to the rural area. 2) The rates of detected parasites according to their kinds are as follows Ascaridae 55.9%, Ancylostomatidae 19.9%, Trichocephalus 13.5%, Trichostrongylus 5.7%, Tenia 3.9%, Enterobius 1.1% 3) The monthly variation of infection rate in the same districts, in the case of Sageun-dong, is, August 25.7%, July 18.9%, June 16.2%, September 15.3% April 12.6%, May 11.3%. The above shows that the infection rate of soil is comparatively higher in the summer season.

• Asian Pacific Journal of Cancer Prevention
• /
• 제16권18호
• /
• pp.8281-8285
• /
• 2016

Background: Helicobacter pylori is a cause of chronic gastritis, peptic ulcer disease, and gastric malignancy, infection being a serious health problem in Thailand. Recently, clarithromycin resistant H. pylori strains represent the main cause of treatment failure. Therefore this study aimed to determine the prevalence and pattern of H. pylori resistance to clarithromycin in Suranaree University of Technology Hospital, Suranree University of Technology, Nakhon Ratchasima, Northeastern Thailand, Nakhon Ratchasima province, northeast of Thailand. Materials and Methods: This hospital-based cross-sectional study was carried out between June 2014 and February 2015 with 300 infected patients interviewed and from whom gastric mucosa specimens were collected and proven positive by histology. The gastric mucosa specimens were tested for H. pylori and clarithromycin resistance by 23S ribosomal RNA point mutations analysis using real-time polymerase chain reactions. Correlation of eradication rates with patterns of mutation were analyzed by chi-square test. Results: Of 300 infected patients, the majority were aged between 47-61 years (31.6%), female (52.3%), with monthly income between 10,000-15,000 Baht (57%), and had a history of alcohol drinking (59.3%). Patient symptoms were abdominal pain (48.6%), followed by iron deficiency anemia (35.3%). Papaya salad consumption (40.3%) was a possible risk factor for H. pylori infection. The prevalence of H. pylori strains resistant to clarithromycin was 76.2%. Among clarithromycin-resistant strains tested, all were due to the A2144G point mutation in the 23S rRNA gene. Among mutations group, wild type genotype, mutant strain mixed wild type and mutant genotype were 23.8%, 35.7% and 40.5% respectively. With the clarithromycin-based triple therapy regimen, the efficacy decreased by 70% for H. pylori eradication (P<0.01). Conclusions: Recent results indicate a high rate of H. pylori resistance to clarithromycin. Mixed of wild type and mutant genotype is the most common mutant genotype in Nakhon Ratchasima province, therefore the use of clarithromycin-based triple therapy an not advisable as an empiric first-line regimen for H. pylori eradication in northeast region of Thailand.

• Pediatric Infection and Vaccine
• /
• 제5권2호
• /
• pp.215-220
• /
• 1998

목 적 : A군 연쇄구균 무증상 감염자는 증상은 없지만 A군 연쇄구균이 분리되고 ASO(antistreptolysin O)치가 높은 사람으로서 이들은 류마티스열이나 사구체신염 등 후유증을 일으킬 수 있다. 저자들은 무증상 감염자를 대상으로 경구용 페니실린을 복용하게 하여 이들에서 페니실린 치료 효과를 조사하였다. 방 법 : 상기도 감염 증상이 없는 건강한 초등 학생들을 대상으로 인두배양과 ASO치를 정량적으로 측정하였다. A군 연쇄구균이 분리되고 ASO 치가 400IU/mL 이상인 아동 36명을 대상으로 하여 그 중 22명의 학생은 경구용 페니실린 제제(penicillin V, 500mg. 하루 2회)를 10일간 복용하게 하였고, 14명은 대조군으로 삼고 항생제를 복용하지 않았다. 한달 후 두 그둡 아동에서 동시에 인두배양을 시행하여 A군 연쇄구균 제거율을 비교하고 ASO치를 측정하여 농도 변화를 관찰하였다. 결 과 : 항생제를 복용한 그룹과 복용하지 않은 그음의 A군 연쇄구균 제거율은 각각 91%(20/22)와 50%(7/14)로서 항생제를 사용한 그룹에서 유의하게 높았다(P<0.05). 항생제를 사용한 그룹과 사용하지 않은 그룹에서 ASO치가 100IU/mL 이상 상승한 경우는 각각 22%(4/18)와 30%(3/10)이었고 200IU/mL이상 감소한 경우는 각각 44.4%(8/18)와 40%(4/10)로서 유의한 차이가 없었다. 결 론 : 무증상 감염자를 대상으로 페니실린을 투여했을 때 인두에서 균이 효과적으로 제거되어 페니실린 치료의 타당성을 확인하였다. 그러나 ASO치 감소는 두 그룹간에 유의한 차이가 없었는데, 이는 ASO의 반감기가 걸고 경구용 페니실린의 경우 순응도가 낮기 때문으로 사료된다. 항생제 치료에도 불구하고 ASO치가 상승한 것을 치료 실패로 판정할 때 22%의 치료 실패율을 보였다.

• 한국작물학회지
• /
• 제59권4호
• /
• pp.498-504
• /
• 2014

Potato virus Y (PVY) and potato leafroll virus (PLRV) are among the most damaging potato viruses and prevalent in most potato growing areas. In this study, cryopreservation was used to eradicate PVY and PLRV using two cryogenic methods. Potato shoot tips proliferated in vitro were cryopreserved through droplet-vitrification and encapsulation-vitrification using plant vitrification solution 2 (PVS2; 30% glycerol + 15% dimethyl sulfoxide + 15.0% ethylene glycol + 13.7% sucrose) and modified PVS2. Both cryogenic procedures produced similar rates of survival and regrowth, which were lower than those from shoot tip culture alone. The health status of plantlets regenerated from shoot tip culture alone and cryopreservation was checked by reverse transcription-polymerase chain reaction. The frequency of virus-free plants regenerated directly from highly proliferating shoot tips reached 42.3% and 48.6% for PVY and PLRV, respectively. In comparison, the frequency of PVY and PLRV eradication after cryopreservation was 91.3~99.7% following shoot-tip culture. The highest cryopreserved shoot tip regeneration rate was observed when shoot tips were 1.0~1.5 mm in length, but virus eradication rates were very similar (96.4~99.7%), regardless of shoot tip size. This efficient cryotherapy protocol developed to eliminate viruses can also be used to prepare potato material for safe long-term preservation and the production of virus-free plants.

• 한국동물위생학회지
• /
• 제26권2호
• /
• pp.135-144
• /
• 2003

Fowl typhoid is a septicemic disease of turkeys and chickens. The antigen is Salmonella(S) gallinarum, which cross-reacts with S pullorum because of common antigen. The organism is maintained in the ovary of carrier birds and transmitted vertically in the york. It is also transmitted horizontally through feces and broken eggs. The symptoms are weakness, drowsiness, wing drooping, hyperexcitability, paresis and diarrhea. In the many cases, the birds are found dead in the morning before any symptoms have been noticed. this experiment was carried out to investigate the characteristics of S gallanarum and scrutinized about the control systems. 1. Fowl typhoid was came about in the winter than the other seasons. The average of mortality was 46.3%. And it was came about not only adult poultry but also chicks. 2. S gallinarum was isolated from liver and spleen in infected chickens. Total isolated strains were 60. 3. The organisms were all extinct at 60$^{\circ}C$, 30mins. 4. A survival rate was higher in underground water than a secondary distilled water. It was detected in underground water until 30 days. 5. When being exposed to the solar light, it became extinct almost within 24 hours. 6. It was survived in a refrigerator until 12 months. 7. It was extinct among 5 mins in 0.1% phenol and 2% formalin. 8. When the cultured organism fluid was inoculated in SD-rat abdominal cavity, rat died within 24 hours. 9. Pullorum-typhoid related program must disciplines in order to destroy the fowl typhoid, and breeding system must be converted to cage system.

• Pediatric Gastroenterology, Hepatology & Nutrition
• /
• 제1권1호
• /
• pp.30-36
• /
• 1998

목 적: H. pylori가 만성유문부 위염의 원인으로 밝혀지면서 십이지장궤양 환자의 90%이상에서 그 위점막에 H. pylori의 존재가 확인되어 H. pylori의 박멸이 십이지장궤양 치료 및 재발에 미치는 영향에 대해 많은 연구가 이루어져 왔고 여러 보고에서 H. pylori의 박멸로 십이지장궤양의 재발율이 현저히 감소한다고 하였다. 소아에서는 성인에 비해 궤양의 빈도가 낮고 내시경적 검사의 제약으로 인하여 이에 대한 관심이 상대적으로 적었으며 소아 십이지장궤양에 대한 연구는 현재까지 거의 없는 실정이다. 이에 저자들은 내시경으로 진단한 소아 십이지장궤양에서 고식적 궤양치료와 H. pylori 병행치료후의 궤양의 재발에 대해 비교 분석해 보고자 하였다. 방 법: 1987년 7월부터 1995년 8월까지 서울대학병원 어린이 병원에 내원하여 내시경검사상 십이지장궤양으로 진단받은 105명(남:여=78:27)을 대상으로, 고식적 치료(ranitidine+antacid)를 행한 군과, H. pylori 진단을 받은 경우 고식적 치료와 함께 amoxicillin(50 mg/kg) 2주, denol(8 mg/kg) 4주의 균박멸 치료를 병행한 군으로 나누어 궤양재발율에 대하여 비교 조사하여 보았다. H. pylori 양성은 내시경생검을 통한 CLO test, Giemsa 염색과 혈청 IgG 항체검사중 둘 이상이 양성이거나 생검조직의 균배양이 양성인 것으로 하였다. 결 과: 1) 91년 5월이후 진단받은 38명(남:여=30:8) 중 원발성 십이지장궤양은 30명(78.9%)이었으며 모두 H. pylori 검사가 시행되어 이중 27명이 양성으로 H. pylori의 감염율은 90.0%였다. 2) H. pylori 양성인 27명 환아에 대해 고식적 치료와 H. pylori 치료를 병행하였는데 추적내시경검사상 23명에서 궤양치유와 함께 균의 박멸이 확인되어 H. pylori 치료성공율은 85.2%였다. 3) 6주의 치료후 추적검사상 박멸에 실패한 3명은 강화요법으로 균의 소실이 확인되었고 이중 1명(33.3%)이 치료종료 2.4년후 재발하였다. 4) 십이지장궤양 환아의 치료후 추적관찰 1년이내 궤양의 재발율은 고식적 치료만을 시행한 경우 65.3%였고 H. pylori 치료를 병행한 경우는 4.3%였다. 결 론: 십이지장궤양 환아들의 대부분이 H. pylori의 감염이 있으며 H. pylori 양성인 소아 십이지장궤양에서 H. pylori 박멸 요법은 궤양 재발의 방지를 위하여 반드시 필요하다.

• Asian Pacific Journal of Cancer Prevention
• /
• 제16권2호
• /
• pp.811-814
• /
• 2015

Background: North East India has a high prevalence of tobacco consumption, but only few individuals seek help for tobacco cessation. Impact of community based tobacco cessation intervention in this part needs more research. Materials and Methods: Retrospective analysis was done on the dataset from a community-based tobacco cessation intervention pilot project conducted in Guwahati metro during 2009-10. Subjects, both male and female tobacco users, age > 15 years, permanent residents of these blocks giving consent were included in the study. Results: The sample was 800 tobacco users, of whom 25% visited any health care provider during last 12 months and 3% received tobacco cessation advice. An 18% quit rate was observed at six weeks follow up, more than the National average, with a 47% quit rate at eight months, while 52% of subjects reduced use. Conclusions: Higher tobacco quit rate and reduced tobacco use, no loss to follow up and negligible relapse was observed with this community based intervention design. Such designs should be given more emphasis for implementation in specified communities with very high tobacco consumption rates, cultural acceptance of tobacco and less motivation towards quitting.

• Clinical and Experimental Reproductive Medicine
• /
• 제26권3호
• /
• pp.339-344
• /
• 1999

Objective: To evaluate incidence of microbial growth from the tip of the embryo transfer catheter after embryo transfer in relation to clinical pregnancy rate following in-vitro fertilization and embryo transfer. Method: This study was performed prospectively at the time of transcervical embryo transfer following conventional in-vitro fertilization and intracytoplasmic sperm injection procedures. Sixty three patients were enrolled in this study. Microbiological cultures were performed on endocervical swabs and embryo transfer catheter tips. Results: Positive microbial growths were observed from endocervical swabs in 45 (71.4%) women and from catheter tips in 30 (47.6%) women. There was no statistically significant difference seen in the mean number of oocytes fertilized or number and grade of embryos transferred between the group of patients without growth and the group of patients with positive microbial growth from catheter tips. The clinical pregnancy rate were 30.3% in the group of patients without growth and 13.3% in the group with positive microbial growth from catheter tips. This difference in clinical pregnancy rates was statistically significant. Conclusion: Our finding is that microbial contamination at embryo transfer may influence implantation rates. The major questions arising from our finding are whether eradication of endocervical micro-organisms is possible and whether their eradication will improve implantation rates.

• 대한두경부종양학회지
• /
• 제7권1호
• /
• pp.17-23
• /
• 1991

The purpose of conservation surgery is complete eradication of the lesion with maximal maintenance of the proper function of the larynx. But the re are various methods of conservation surgery for the laryngeal cancer because of the unique embriological and anatomical characteristics of the larynx, which is the narrowest portion of the upper airway. The authors experienced 24 cases of conservation surgery for laryngeal cancer(7 in supraglottie cancer, 13 in glottic cancer, 4 in transglottic cancer) during recent 5 years and performed retrospective analysis of the cases. The result shows 91.6% of overall 3 years survival rate(87.5% of disease free 3 year survival rate). The authors concluded that conservation surgery for the laryngeal cancer preserve the function of larynx as possible and high cure rates were achieved by postoperative radiation therapy for the incomplete resection margin.