• Journal of the Korean Society of Marine Environment & Safety
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• v.23 no.7
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• pp.933-940
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• 2017

Draught and trim conditions are highly related to the loading condition of a vessel and are important factors in predicting ship manoeuverability. This paper estimates hydrodynamic coefficients from sea trial measurements with three different trim and draught conditions. A mathematical optimization method for system identification was applied to estimate the forces and moment acting on the hull. Also, fast time simulation software based on the Rheinmetall Defense model was applied to the whole estimation process, and a 4,500 Twenty-foot Equivalent Unit (TEU) class container carrier was chosen to collect sets of measurement data. Simulation results using both optimized coefficients and newly-calculated coefficients for validation agreed well with benchmark data. The results show mathematical optimization using sea measurement data enables hydrodynamic coefficients to be estimated more simply.

• Journal of Korean Academy of Nursing
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• v.51 no.4
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• pp.478-488
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• 2021

Purpose: This study aimed to develop and examine the effects of a prenatal program on environmental health behavior using cartoon comics among Korean pregnant women. Methods: This study used a non-equivalent control group pre-test/post-test design. The program used cartoon comics to explore environmental health behaviors during pregnancy. The program consisted of the following four components: environmental toxicants during pregnancy, avoiding particulate matter during pregnancy, environmental toxicants during baby care, and making a healthy environment for children. In total, 35 pregnant women participated in the study: 18 in the experimental group and 17 in the control group. Data collection and program adaptation were conducted between November 3, 2020 and January 19, 2021. The effect of the prenatal education program was evaluated by t-test and repeated measures ANOVA. Results: Learning experience (t = - 2.35, p = .025), feasibility (t = - 2.46, p = .019), satisfaction (t = - 2.23, p = .032) were higher in the experimental group than in the control group in the first post-test. Feasibility (t = - 2.40, p = .022) was higher in the experimental group than in the control group in the second post-test. Repeated-measures ANOVA showed significant interactions between time and group in environmental susceptibility (F = 9.31, p < .001), self-efficacy (F = 3.60, p = .033), and community behavior (F = 5.41, p = .007). Conclusion: This study demonstrates the need for a prenatal education program to promote environmental health perceptions and behavior during pregnancy. We suggest a prenatal class adopting the creative cartoon comics to promote the maternal environmental health behaviors.

• The Korea Journal of Herbology
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• v.32 no.4
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• pp.33-38
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• 2017

Objectives : Termitomyces albuminosus (Berk.) Heim is one of the famous wild edible mushrooms in the southern part of China. It is known that Termitomyces albuminosus, like Aconitum koreanum used in Korean traditional medicine, contains a kind of cerebroside, termitomycesphin, causing a pharmacologic effect on the neuron system. The pharmacologic effect of Termitomyces albuminosus can be used to possibly replace Aconitum koreanum. However, It needs to be certified as safe before it can be used. Here, a single-oral toxicity test and safety classification was conducted to obtain acute information of the toxicity of dried-Termitomyces albuminosus powder and to secure its safety in clinical applications. Methods : In order to calculate approximate lethal dose(ALD), test substance was orally administered to male and female SD-rat at dose levels of 5,000 and 0 (vehicle control) mg/kg (body weight). Based on the result of this toxicity, also the estimation of safety classification was calculated using the HED-based (human equivalent dose) MOS (margin of safety). Results : There were no mortalities, test substances treatment-related clinical signs, no changes in the body or organ weights, and no gross or histopathological findings at 14 days after treatment with test substance. Thus, the approximate lethal dose of dried-Termitomyces albuminosus powder was considered over 5,000 mg/kg in both female and male mice. Conclusions : Based on the limit dose, 5000 mg/kg, it was estimated that dried-Termitomyces albuminosus powder is classified as "Specified class B" indicating that clinical dose is not limited to patients as safe as food.

• The Korea Journal of Herbology
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• v.33 no.4
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• pp.53-58
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• 2018

Objectives : Kaempferia parviflora Rhizome is black ginger indigenous to Laos and Thailand. It has been used as a folk medicine to improve blood flow and promote vitality and longevity with good health and well being. For these reasons, Kaempferia parviflora Rhizome has been focused on developing it as a food or food supplement. In addition, Kaempferia parviflora Rhizome could be under consideration of new prescription based on its characteristic compounds, polymethoxyflavonoids. However, it needs to be certified as safe before it can be used. Here, a single-oral toxicity test and safety classification was carried out to identity acute information of the toxicity of Kaempferia parviflora Rhizome powder and to make sure of its safety in clinical applications. Methods : Test substance was orally administered to male and female SD-rat at dose levels of 5000 mg/kg to estimate approximate lethal dose(ALD). Based on the acute information of the toxicity, the safety classification was estimated using the HED(human equivalent dose)-based MOS(margin of safety). Results : At 14 days after treatment with test substance. there were no of test substance related with mortalities and clinical signs. In addition, no changes in the body or organ weights and no gross or histopathological findings were observed. Thus, the ALD of Kaempferia parviflora Rhizome powder was considered over 5,000 mg/kg in both female and male mice. Conclusions : Based on the single oral toxicity test using the highest and limit dose, 5,000 mg/kg and the decision guideline for safety classification based on HED-based MOS, it was estimated that Kaempferia parviflora Rhizome powder is classified as "Specified class B" indicating that clinical dose is not limited to patients as safe as food.

• Transactions of the Korean hydrogen and new energy society
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• v.33 no.3
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• pp.247-254
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• 2022

Slush hydrogen containing liquid and solid hydrogen is expected to achieve zero boil-off by suppressing boil-off gas because heat of fusion for solid absorbe the heat ingress from atmosphere. In this paper, quantitative analysis on storage cost considering specific energy consumption between 1,000 m³ class liquid hydrogen storage system with re-liquefaction and slush hydrogen storage system during equivalent zero boil off period. Even though approximately 50% of total storage capacity should be converted into solid phase during the initial cargo bunkering, total energy consumption to convert into slush hydrogen is relatively 25% less than re-liquefaction energy for boil off hydrogen during zero boil off period. That's because energy consumption of slush phase change take up only 1.8% of liquefaction energy. moreover, annual revenue requirement including CAPEX, OPEX and electric cost for slush hydrogen storage could be more reduced approximately 32.5% than those of liquid hydrogen storage and specific energy storage cost ($/kg-H₂) could also be lowered by about 41.7% compared with liquid hydrogen storage.

• Journal of the Korea Concrete Institute
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• v.24 no.6
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• pp.633-641
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• 2012

In this study, the effects of the inelastic shear behavior of beam-column joint on the response of RC OMRF are evaluated in the inelastic time history analysis. For an example, a 5-story structure for site class SB and seismic design category C was designed in accordance with KBC2009. Bending moment-curvature relationship for beam and column was evaluated using fiber model and bending moment-rotation relationship for beam-column joint was calculated using simple and unified joint shear behavior model and moment equilibrium relationship. The hysteretic behavior was simulated using three-parameter model suggested in IDARC program. The inelastic time history analysis with PGA for return period of 2400 years showed that the model with inelastic beam-column joint yielded smaller maximum base shear force but nearly equivalent maximum roof displacement and maximum story drift as those obtained from analysis using rigid joint. The maximum story drift satisfied the criteria of KBC2009. Therefore, the inelastic shear behavior of beam-column joint could be neglected in the structural design.

• Journal of Forest and Environmental Science
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• v.36 no.2
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• pp.91-112
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• 2020

In Ethiopia, dry land vegetation including the fairly intact lowland and western escarpment woodlands occupy the largest vegetation resource of the country. These forests play a central role in environmental regulation and socio-economic assets, yet they received less scientific attention than the moist forests. This study evaluated the woody plant species composition, population structure and carbon sequestration potential of the A. senegal woodland across three distance gradients from the settlements. A total of 45 sample quadrants were laid along a systematically established nine parallel transect lines to collect vegetation and soil data across distance gradients from settlement. Mature tree dry biomass with DBH>2.5 cm was estimated using allometric equations. A total of 41 woody plant species that belong to 20 families were recorded and A. senegal was the dominant species with 56.4 IVI value. Woody plant species diversity, density and richness were significantly higher in the distant plots compared to the nearest plots to settlement (p<0.05). The cumulative DBH class distribution of all individuals had showed an interrupted inverted J-shape population pattern. There were 19 species without seedlings, 15 species without saplings and 14 species without both seedlings and saplings. A significant above ground carbon (5.3 to 12.7 ton ha^-1), root carbon (1.6 to 3.6 ton ha^-1), soil organic carbon (35.6 to 44.5 ton ha^-1), total carbon stock (42.5 to 60.7 ton ha^-1) and total carbon dioxide equivalent (157.7 to 222.8 ton ha^-1) was observed consistently with an increasing of distance from settlement (p<0.05). Distance from settlement had significant and positive correlation with species diversity and carbon stock at 0.64^⁎⁎ and 0.78^⁎⁎. Disturbance intensity may directly influence the variation of species composition, richness and density along the A. senegal woodland. The sustainability of the A. senegal woodland needs urgent protection, conservation and restoration.

• Radiation Oncology Journal
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• v.33 no.4
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• pp.276-283
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• 2015

Purpose: We evaluated the efficacy and toxicity of repeated high dose 3-dimensional conformal radiation therapy (3D-CRT) for patients with unresectable hepatocellular carcinoma. Materials and Methods: Between 1998 and 2011, 45 patients received hepatic re-irradiation with high dose 3D-CRT in Samsung Medical Center. After excluding two ineligible patients, 43 patients were retrospectively reviewed. RT was delivered with palliative or salvage intent, and equivalent dose of 2 Gy fractions for ${\alpha}/{\beta}=10Gy$ ranged from $31.25Gy_{10}$ to $93.75Gy_{10}$ (median, $44Gy_{10}$). Tumor response and toxicity were evaluated based on the modified Response Evaluation Criteria in Solid Tumors criteria and the Common Terminology Criteria for Adverse Events (CTCAE) ver. 4.0. Results: The median follow-up duration was 11.2 months (range, 4.1 to 58.3 months). An objective tumor response rate was 62.8%. The tumor response rates were 81.0% and 45.5% in patients receiving ${\geq}45Gy_{10}$ and $<45Gy_{10}$, respectively (p = 0.016). The median overall survival (OS) of all patients was 11.2 months. The OS was significantly affected by the Child-Pugh class as 14.2 months vs. 6.1 months (Child-Pugh A vs. B, p < 0.001), and modified Union for International Cancer Control (UICC) T stage as 15.6 months vs. 8.3 months (T1-3 vs. T4, p = 0.004), respectively. Grade III toxicities were developed in two patients, both of whom received ${\geq}50Gy_{10}$. Conclusion: Hepatic re-irradiation may be an effective and tolerable treatment for patients who are not eligible for further local treatment modalities, especially in patients with Child-Pugh A and T1-3.

• Women's Health Nursing
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• v.13 no.4
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• pp.245-253
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• 2007

Purpose: The purpose of this study was to measure the effects of a breastfeeding management program for promotion of breastfeeding. Method: The study design was a non-equivalent control group pre-post test. The study subjects were pregnant women receiving a breastfeeding education class in one hospital in Ilsan. The total number of study subjects was 153 pregnant women, namely 75 mothers in the experimental group and 78 in the control group. Data was collected between June and November, 2006. A breastfeeding management program was provided to the experimental group while admitted for delivery, and in weeks 2, 4, 8, 12, 16, 20, and 24 of the postpartum period. The rates of breastfeeding were measured in weeks 2, 4, 8, 12, 16, 20, and 24 of the postpartum period. Result: There were significant differences in the scores of rate of breastfeeding between the two groups(all cases), which were 93.1 in the experimental group and 85.8 in the control group at week 4; 88.1 vs 71.8 at week 8; 83.4 vs 56.7 at week 12; 71.4 vs 53.9 at week 16; and 65.7 vs 48.4 at week 20 respectively. However, there were not significant differences in the scores of rate of breast-feeding between the two groups, which were 97.7 in the experimental group and 96.0 in the control group in the early postpartum period at week 2, and 59.6 vs 45.3 at week 24. Add to this, the study analyzed only people who had jobs. As a result, the scores of rate of breastfeeding were 94.8 in the experimental group which were significantly higher than 88.5 in the control group at week 4; 93.2 vs 73.3 at week 8; 89.6 vs 57.2 at week 12; and 75.0 vs 46.0 at week 20 respectively. However, there were not significant differences at week 2, week 16 and week 24. Conclusion: The results of this study suggest that a breastfeeding management program during the last trimester of the perinatal period and postpartum period may increase the duration of breastfeeding in postpartum clients who intend to breastfeed. This study supports the literature which found that prenatal education and postpartum support are important to the outcome of breastfeeding.

• Radiation Oncology Journal
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• v.36 no.1
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• pp.25-34
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• 2018

Purpose: This study aimed to evaluate the initial outcomes of proton beam therapy (PBT) for hepatocellular carcinoma (HCC) in terms of tumor response and safety. Materials and Methods: HCC patients who were not indicated for standard curative local modalities and who were treated with PBT at Samsung Medical Center from January 2016 to February 2017 were enrolled. Toxicity was scored using the Common Terminology Criteria for Adverse Events (CTCAE) version 4.0. Tumor response was evaluated using modified Response Evaluation Criteria in Solid Tumors (mRECIST). Results: A total of 101 HCC patients treated with PBT were included. Patients were treated with an equivalent dose of $62-92GyE_{10}$. Liver function status was not significantly affected after PBT. Greater than 80% of patients had Child-Pugh class A and albumin-bilirubin (ALBI) grade 1 up to 3-months after PBT. Of 78 patients followed for three months after PBT, infield complete and partial responses were achieved in 54 (69.2%) and 14 (17.9%) patients, respectively. Conclusion: PBT treatment of HCC patients showed a favorable infield complete response rate of 69.2% with acceptable acute toxicity. An additional follow-up study of these patients will be conducted.