• Title/Summary/Keyword: ep

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The Effect of Epoxy Resin on the Properties of Encapsulated Fire Extinguishing Agent (캡슐화된 소화약제의 물성에 대한 고분자 매트릭스의 효과)

  • Alexandra, Sertsova;Sergei, Krasilnikov;Lee, Sang-Sup;Kim, Jong-Sang.
    • Fire Science and Engineering
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    • v.33 no.5
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    • pp.19-27
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    • 2019
  • Fire extinguishing composite materials based on low-viscosity epoxy resin (EP) and containing 50 wt% of encapsulated fire extinguishing agent (EFA) have been studied. The positive effect of the EP on the kinetics and temperature of the EFA decapsulation was established. The EP increases the decapsulation temperature of the EFA from 130 ℃ to 155 ℃ and changes the kinetics of the decapsulation. The epoxy matrix increases the thermal stability of the EFA more than 3.9 times compared to that of the pure EFA. The protective effect of the EP on the storage stability of the EFA was validated. The mass loss of EP-containing EFA at 60 ℃ and 80% humidity over 96 h is 0.4%. The mass loss of pure EFA under the same conditions is 15%. A similar effect was observed under ultraviolet radiation: the EP-containing EFA loses 0.8% at pure EFA mass of 6%. The testing of alternative polymer matrixes has been considered.

Immune Responses to Plant-Derived Recombinant Colorectal Cancer Glycoprotein EpCAM-FcK Fusion Protein in Mice

  • Lim, Chae-Yeon;Kim, Deuk-Su;Kang, Yangjoo;Lee, Ye-Rin;Kim, Kibum;Kim, Do Sun;Kim, Moon-Soo;Ko, Kisung
    • Biomolecules & Therapeutics
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    • v.30 no.6
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    • pp.546-552
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    • 2022
  • Epidermal cell adhesion molecule (EpCAM) is a tumor-associated antigen (TAA), which has been considered as a cancer vaccine candidate. The EpCAM protein fused to the fragment crystallizable region of immunoglobulin G (IgG) tagged with KDEL endoplasmic reticulum (ER) retention signal (EpCAM-FcK) has been successfully expressed in transgenic tobacco (Nicotiana tabacum cv. Xanthi) and purified from the plant leaf. In this study, we investigated the ability of the plant-derived EpCAM-FcK (EpCAM-FcKP) to elicit an immune response in vivo. The animal group injected with the EpCAM-FcKP showed a higher differentiated germinal center (GC) B cell population (~9%) compared with the animal group injected with the recombinant rhEpCAM-Fc chimera (EpCAM-FcM). The animal group injected with EpCAM-FcKP (~42%) had more differentiated T follicular helper cells (Tfh) than the animal group injected with EpCAM-FcM (~7%). This study demonstrated that the plant-derived EpCAM-FcK fusion antigenic protein induced a humoral immune response in mice.

Effect of Enteromorpha prolifera on Quality Characteristics and Antioxidants Activities of the Makgeolli (Korean Traditional Rice-Based Wine) (가시파래(Enteromorpha prolifera)가 첨가된 막걸리의 품질 특성 및 항산화 활성)

  • Kim, Ji Yoon;Jeon, Eun Bi;Choi, Man-Seok;Park, Shin Young
    • Korean Journal of Fisheries and Aquatic Sciences
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    • v.53 no.2
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    • pp.231-236
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    • 2020
  • The objective of the current study was to evaluate the quality characteristics (alcohol contents and antioxidant capacities) and sensory characteristics of the Korean traditional rice-based wine, Makgeolli supplemented with 5% and 10% Enteromorpha prolifera (Ep) during an 8-days cold storage at 4℃. The alcohol content in the unsupplemented Makgeolli (control) and Ep Makgeolli gradually increased from day 0 to day 8 (control, 2.05-8.03; 5% Ep, 2.15-9.03; 10% Ep, 3.15-10.07). The DPPH (1,1-diphenyl-2-picrylhydrazyl) radical scavenging activities was significantly higher in the 10% Ep Makgeolli (75.87%) than 5% Ep Makgeolli (57.34%) and control (21.91%). The ABTS [2,2'-azinobis(3-ethylbenzothiazoline-6-sulfonic acid)] radical scavenging activities were also significantly higher in the 10% Ep Makgeolli (90.85%) than 5% Ep Makgeolli (75.94%) and control (47.21%). Makgeolli supplemented with 10% Ep had the highest color, smell, taste, and overall acceptance scores. The current study suggest that Makgeolli supplemented with 10% Ep could be potentially developed because of its high antioxidant properties and good consumer acceptance.

A Study on the Optimization of Deburring Process for the Micro Channel using EP-MAP Hybrid Process (전해-자기 복합 가공을 이용한 마이크로 채널 디버링공정 최적화)

  • Lee, Sung-Ho;Kwak, Jae-Seob
    • Journal of the Korean Society of Manufacturing Technology Engineers
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    • v.22 no.2
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    • pp.298-303
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    • 2013
  • Magnetic abrasive polishing is one of the most promising finishing methods applicable to complex surfaces. Nevertheless this process has a low efficiency when applied to very hardened materials. For this reason, EP-MAP hybrid process was developed. EP-MAP process is expected to machine complex and hardened materials. In this research, deburring process using EP-MAP hybrid process was proposed. EP-MAP deburring process is applied to micro channel, thereby it can obtain both deburring process and polishing process. EP-MAP deburring process on the micro channel was performed. Through design of experiment method, error of height in this process according to process parameter is analyzed. When the level 1 parameter A(magnetic flux density) and level 2 parameter B(electric potential), C(working gap) and level 3 parameter D(feed rate) are applied in the deburring process using EP-MAP hybrid process, it provides optimum result of EP-MAP hybrid deburring process.

Growth Performance and Digestive Characteristics of Starry Flounder Platichthys stellatus on the Moist and Extruded Pellets (습사료와 부상사료에 대한 강도다리(Platichthys stellatus)의 성장과 소화 특성)

  • Kim, Pyong Kih
    • Korean Journal of Fisheries and Aquatic Sciences
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    • v.45 no.6
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    • pp.679-685
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    • 2012
  • A study was carried out to observe the effects of feed types on the growth, feed preference, and enteric feed transition rate of juvenile starry flounder, Platichthys stellatus for 45 days. Fifty fish (avg. 135 g) were stocked each in replication, and fed a commercial extruded pellet diet (EP, 45% protein) and a moist pellet diet (MP, 65% raw mackerel+35% feed powder in wet basis), respectively. The MP presented the higher performance than that of the EP on the feed efficiency ($68.3{\pm}0.9%$ for EP and $92.3{\pm}4.3%$ for MP) and the specific growth rate ($1.07{\pm}0.07$ for the EP and $1.20{\pm}0.05%$ for the MP). In contrast, the EP showed the higher feed preference in terms of the daily feed intake ($1.57{\pm}0.08%$ for the EP and $1.30{\pm}0.01$ for the MP) and the ad libitum feeding rate after a fast of 72 hours (1.73% for the EP and 1.35% for the MP). The feed transition rate through intestinal canals decreased exponentially in both the EP and the MP, showing the faster transition rate with the EP. In the result, starry flounder appeared to have the better feed preference to the EP, but have the higher feed efficiency and growth performance to the MP.

Improved Thermal Conductivities of Epoxy Resins Containing Surface Functionalized BN Nanosheets

  • Weng, Ling;Wang, HeBing;Zhang, Xiaorui;Liu, Lizhu;Zhang, Hexin
    • Nano
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    • v.13 no.11
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    • pp.1850133.1-1850133.9
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    • 2018
  • The hexagonal boron nitride nanosheets (BN) were firstly treated by silane coupling agents 3-aminopropyltriethoxysilane (KH550) and 3-glycidoxypropyl-trimethoxysilane (KH560) to introduce some amino and epoxy (EP) groups on the BN surface. These modified BN nanosheets were incorporated into an EP matrix to prepare BN@KH560/EP composites with excellent thermal conductivity and electrical insulation properties. Results showed that the thermal conductivity of BN@KH560/EP composite with 20 vol% BN dosage was found to be 0.442 W/($m{\cdot}K$), which was 81% higher than that of pure EP resin. Both BN/EP composites treated by KH550 and KH560 showed rather good electrical insulation properties, although the dielectric constant of BN@KH550/EP composites were slightly higher than BN@KH560/EP composites. Moreover, BN@KH560/EP composites also showed better thermal and mechanical properties than that of BN@KH550/EP composites.

Effect of Extruded and Moist Pellets at Different Feeding Rate on Growth and Body Composition of Juvenile Flounder, Paralichthys olivaceus (부상 건조사료(EP) 습사료(MP)의 만복 및 제한 공급이 넙치 치어의 성장 및 체조성에 미치는 영향)

  • Seo Joo-Young;Lee Jong Ha;Kim Gun-Up;Lee Sang-Min
    • Journal of Aquaculture
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    • v.18 no.1
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    • pp.26-30
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    • 2005
  • A 10-week feeding trial was conducted to determine the optimum feeding rate of two extruded pellets (EP1 and EP2) and raw fish-based moist pellet (MP) for juvenile flounder. Two replicate groups of the fish (average weight of 27 g) were fed EP and MP three times daily at different feeding rate (satiation and $85\%$ satiation). Weight gain of fish was not affected by diet, but affected by feeding rate. Weight gain with satiation feeding group showed :t tendency to higher compared to that of fish with $85\%$ satiation feeding at the same diet. Feed efficiency of fish was affected by diet, but not feeding rate. Feed efficiency of fish fed the EP1 and EP2 was higher than that of fish fed the MP at the same feeding rate. Daily feed intake was affected by diet and feeding rate. Daily feed intake of fish fed with satiation was higher than that of fish with $85\%$ satiation at same diet, and this variable of fish fed the MP was higher than that of fish fed the EP 1 and EP2. Protein efficiency ratio of fish fed the MP was significantly lower than that of fish fed the EP1 and EP2 regardless of feeding rate. Lipid content of whole body was affected by diet, and that of fish fed the EP2 and MP at satiation feeding was the highest. It can be concluded that satiation feeding will be good and EP is better than MP for growth of juvenile flounder grown from 27 g to 51 g.

Long-term Evaluation of Muscle Quality of the Olive Flounder, Paralichthys olivaceus, Fed with Extruded Pellet (배합사료로 장기간 사육된 넙치의 육질평가)

  • Kim, Kang-Woong;Kang, Yong-Jin;Kim, Kyoung-Duck;Choi, Se-Min;Lee, Jong-Yun;MoonLee, Hae-Young;Bai, Sung-Chul C.
    • Journal of Aquaculture
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    • v.20 no.1
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    • pp.51-55
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    • 2007
  • This study was conducted to evaluate the muscle quality of the olive flounder fed on extruded pellet (EP) diets compared with a raw fish moist pellet (MP) diet for olive flounder, Paralichthys olivaceus in a commercial scale for a year. The sensory and physical qualities and palatable compounds were compared for evaluation of muscle quality in fish. Four diets were formulated for this experiment: two experimental EP diets (EP 1 and 2), one commercial EP diet (CEP) and MP diet. Crude lipid of fish fed EP1 and EP2 was significantly higher (P<0.05) than that of fish fed CEP, but not significantly different from that of fish fed MP (P>0.05). In the palatable compounds, the free amino acids composition were much alike in that of all the diets. Proline, glycine and alanine from fish fed diet EPs were the most abundant compound among amino acid compositions. There was little difference in the free amino acid compositions of all flounder from localities and the growing conditions between wild and cultured fishes. Taurine of fish fed EP1 was dominantly high over that of fish fed EP2, CEP and MP. In all nucleotides and their related compounds, ATP and IMP from fish fed EP diets were higher (P<0.05) than those of fish fed MP. In the sensory score, overall-acceptability of fish fed EP2 were significantly higher (P<0.05) than that of fish fed EP1, CEP and MP. Hardness of physical properties from fish fed EP2 was significantly higher (P<0.05) than those of fish fed CEP (P<0.01). These results strongly suggest that diets EP could be developed to replace MP diet for the grow-out stage of olive flounder without adverse effect on growth performance.

Effects of Ethyl Pyruvate on Allodynia, TNF-${\alpha}$ Expression, and Apoptosis in the Dorsal Root Ganglion after Spinal Nerve Ligation Injury

  • Choi, Dae-Kee;Leem, Jeong-Gill;Shin, Jin-Woo;Suh, Jeong-Hun
    • The Korean Journal of Pain
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    • v.25 no.4
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    • pp.213-220
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    • 2012
  • Background: It has been demonstrated that the expression of tumor necrosis factor-${\alpha}$ (TNF-${\alpha}$) and apoptotic cell death in the dorsal root ganglion (DRG) following spinal nerve constriction injury play a role in the initiation and continuation of hyperalgesia and allodynia. The present study was designed to investigate the effects of ethyl pyruvate (EP) on mechanical and cold allodynia, TNF-${\alpha}$ expression, and apoptosis in DRG after spinal nerve ligation injury. Methods: Rats were divided into 3 groups: control, pre-EP, and post-EP. EP (50 mg/kg) was intraperitoneally injected 30 minutes before (pre-EP) or after (post-EP) surgery. Behavioral tests to determine mechanical and cold allodynia were conducted before surgery and 4 and 7 days after surgery. Seven days after surgery, TNF-${\alpha}$ protein levels in DRG were evaluated by enzyme-linked immunosorbent assay, and DRG apoptosis was determined by immunohistochemical detection of activated caspase-3. Results: Treatment with EP significantly reduced mechanical and cold allodynia following spinal nerve ligation injury. TNF-${\alpha}$ protein levels in the pre-EP ($4.7{\pm}1.2$ pg/200 ${\mu}g$; P < 0.001) and post-EP ($6.4{\pm}1.8$ pg/200 ${\mu}g$; P < 0.001) groups were 2-3 times lower than the control group ($14.4{\pm}1.2$ pg/200 ${\mu}g$). The percentages of neurons and satellite cells that co-localized with caspase-3 were also significantly lower in the pre-EP and post-EP groups than the control group. Conclusions: These results demonstrate that EP has a strong anti-allodynic effect that acts through the inhibition of TNF-${\alpha}$ expression and apoptosis in DRG after spinal nerve ligation injury.

Antioxidant Activities of Eggplant (Solanum melongena) Powder with Different Drying Methods and Addition Levels to Pork Sausages

  • Sembring, Hanna Seprina br;Chin, Koo Bok
    • Food Science of Animal Resources
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    • v.41 no.4
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    • pp.715-730
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    • 2021
  • The objective of this study was to evaluate antioxidant activities of eggplant (EP) powder with different drying methods and addition levels to pork sausages to improve product quality. Antioxidant activities of EP with different drying methods, particle sizes, and solvents of extraction were determined. Freeze dried (FD) EP extracted with 100% ethanol had higher 2,2-diphenyl-1picrylhydrazyl radical-scavenging activities (DPPH-RSA) and total phenolic content (TPC) values than other drying methods. FD500 had the highest iron chelating ability (ICA) value. Oven-dried (OD) EP at 60℃ had the highest reducing power. Dried EP was added to sausages of six groups: control without EP, reference added with ascorbic acid, O1 and O2 added with 0.25% and 0.5% OD EP, respectively, and F1 and F2 added with 0.25% and 0.5% FD EP, respectively. Pork sausages added with O2 had the lowest TBARS and TPC values. These values increased during storage. Purge loss (%), lightness (L*), and redness (a*) values of F2 were lower than those of other groups, whereas sausages containing F2 had the highest yellowness (b*). pH values of sausages added with EP were increased regardless of the level of EP added. Hardness values of F2 were higher. However, there were no significant differences in other textural characteristics. Sausages added with EP had higher moisture and protein contents (%), but lower fat contents (%). These results indicate that EP powder could be used to retard lipid oxidation and inhibit microbial counts during storage time.