• 국제학술발표논문집
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• The 9th International Conference on Construction Engineering and Project Management
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• pp.1242-1242
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• 2022

Annually, several construction workers fall ill, are injured, or die due to heat-related exposure. The prevalence of work-related heat illness may rise and become an issue for workers operating in temperate climates, given the increase in frequency and intensity of heatwaves in the US. An increase in temperature negatively impacts physical exertion levels and mental state, thereby increasing the potential of accidents on the job site. To reduce the impact of heat stress on workers, it is critical to develop and implement measures for monitoring physical exertion levels and mental state in hot conditions. For this, limited studies have evaluated the utility of wearable biosensors in measuring physical exertion and mental workload in hot conditions. In addition, most studies focus solely on male participants, with little to no reference to female workers who may be exposed to greater heat stress risk. Therefore, this study aims to develop a process for objective and continuous assessment of worker physical exertion and mental workload using wearable biosensors. Physiological data were collected from eight (four male and four female) participants performing a simulated drilling task at 92oF and about 50% humidity level. After removing signal artifacts from the data using multiple filtering processes, the data was compared to a perceived muscle exertion scale and mental workload scale. Results indicate that biosensors' features can effectively detect the change in worker physical and mental state in hot conditions. Therefore, wearable biosensors provide a feasible and effective opportunity to continuously assess worker physical exertion and mental workload.

• 한국미생물생명공학회:학술대회논문집
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• 한국미생물생명공학회 2002년도 학술발표대회
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• pp.66-66
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• 2002

• Journal of Microbiology and Biotechnology
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• 제29권10호
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• pp.1522-1542
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• 2019

To adapt to environmental changes and to maintain cellular homeostasis, microorganisms adjust the intracellular concentrations of biochemical compounds, including metal ions; these are essential for the catalytic function of many enzymes in cells, but excessive amounts of essential metals and heavy metals cause cellular damage. Metal-responsive transcriptional regulators play pivotal roles in metal uptake, pumping out, sequestration, and oxidation or reduction to a less toxic status via regulating the expression of the detoxification-related genes. The sensory and regulatory functions of the metalloregulators have made them as attractive biological parts for synthetic biology, and the exceptional sensitivity and selectivity of metalloregulators toward metal ions have been used in heavy metal biosensors to cope with prevalent heavy metal contamination. Due to their importance, substantial efforts have been made to characterize heavy metal-responsive transcriptional regulators and to develop heavy metal-sensing biosensors. In this review, we summarize the biochemical data for the two major metalloregulator families, SmtB/ArsR and MerR, to describe their metal-binding sites, specific chelating chemistry, and conformational changes. Based on our understanding of the regulatory mechanisms, previously developed metal biosensors are examined to point out their limitations, such as high background noise and a lack of well-characterized biological parts. We discuss several strategies to improve the functionality of the metal biosensors, such as reducing the background noise and amplifying the output signal. From the perspective of making heavy metal biosensors, we suggest that the characterization of novel metalloregulators and the fabrication of exquisitely designed genetic circuits will be required.

• 한국산학기술학회논문지
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• 제5권1호
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• pp.87-92
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• 2004

This review focuses on the developed and the being developed environmental sensors in particular biological sensors. As well as discussing the classification and some main principles, presenting current trend of the environmental sensors is given. Two main categories are immunosensors and catalytic sensors. In addition to those. DNA or RNA sensors or protein based sensors are discussed. Some crucial examples of the applications of such sensors are given to show how the sensor technology it used for environmental and biological monitoring, biomarkers of exposure.

• 한국농업기계학회:학술대회논문집
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• 한국농업기계학회 2000년도 THE THIRD INTERNATIONAL CONFERENCE ON AGRICULTURAL MACHINERY ENGINEERING. V.I
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• pp.76-100
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• 2000

바이오 센서의 본질과 기능에 관한 일반적인 논의가 간단히 제시되었다. 바이오 센서개발에 대한 주 동기는 건강관리 산업이었지만, 최근의 연구 노력은 농업 및 생물 생산시스템에서의 문제로 확산되고 있다. 우리 실험실에서 연구된 것들을 설명하기 위하여 세 가지의 바이오 센서 예와 그들의 적용에 대해 소개한다. 첫째는 젖소의 번식관리 향상을 위해 프로게스테론 호르몬을 착유할 때 측정하는 면역센서이다. 둘째는 우유에 있는 요소(尿素, urea)의 측정을 위한 효소 센서로서, 투여되는 단백질의 우유 단백질로의 전환효율을 구하기 위한 도구이며 이로 인해 젖소의 사양관리를 향상시킬 수 있다. 셋째는 신선하며 최소 가공된 야채와 과일을 씻은 물에 있는 극소량의 병원성 박테리아를 검출하기 위한 PCR(중합효소연쇄반응)을 이용한 DNA 센서이다. 농업과 농업생물공학, 식품가공 그리고 환경 모니터링에 있어서의 바이오 센서의 적용 가능성은 이제 겨우 이해되고 있다.

• 한국환경농학회지
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• 제17권4호
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• pp.371-378
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• 1998

Pesticide has played important role in Korean and Austrailian agriculture. In addition, pesticides are the most reliable tools pests in agriculture. Recently, it is highly recommended that the use of pesticide should be concerned with both atricultural and environmental aspect, also legislation on environmental contamination has been fortified to the world. Particularly, the attention on agrochemicals has been focused on the soil abuse and the water contamination at present time. In spite of this kind of concern, a few research about pesticides using in Australia and Korean have been conducted to their behaviors under australian and korean environment to avoid environmental contamination by pesticides. Thus, the research organizations need facilities to analyze the characteristics of each pesticide and the environmental fate of pesticides. The conventional analytical method to detect pesticides and their metabolites can not be overcome to reduce time, expenditure, and complexity of analysis even though the methods are accurate and precise. For example, High performance liquid chromatography(HPLC), and gas chromatography (GC) used until now are less choice detectors and often lower sensitive. In contrast to the conventional analytical methods, biosensors are so fast in analysis and has high productivity and analyze multi=sample simultaneously. Therefore, it is biosensing analytical method that we could consider as an alternative method intead of the conventional methods.

• KSBB Journal
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• 제18권2호
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• pp.79-89
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• 2003

This article contains an overview of acoustic wave devices, the theory and application of piezoelectric quartz crystal microbalances(PZ QCM), clinical analysis, gas phase detection, DNA biosensors, drug analysis, food microbial analysis and environmental analysis.

• Rapid Communication in Photoscience
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• 제2권1호
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• pp.9-17
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• 2013

Visible light-sensitive $TiO_2$ and ZnO nanostructure materials have attracted great attention as the promising material for solar energy conversion systems such as photocatalysts for water splitting and environmental purification as well as nano-biosensors. Success of their applications relies on how to control their surface state behaviors related to the exciton dynamics and optoelectronic properties. In this paper, we briefly review some recent works on single nanoparticle photoluminescence (PL) technique and its application to observation of their surface state behaviors which are raveled by the conventional ensemble-averaged spectroscopic techniques. This review provides an opportunity to understand the temporal and spatial heterogeneities within an individual nanostructure, allowing for the potential use of single-nanoparticle approaches in studies of their photoenergy conversion and nano-scale optical biosensing.

• 한국환경보건학회지
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• 제38권2호
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• pp.83-94
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• 2012

The research on microbial fuel cells (MFCs) needs various knowledge of different fields such as electrochemistry, microbiology, environmental engineering, and material engineering. Although electrochemically active bacteria are very diverse, the performance of MFCs is affected primarily by the structure of the reactor system. Thus, the development in the system architecture is critical to lower internal resistance and increase power generation for commercialization. This paper summarizes the principles of MFCs and demonstrates the infinite potential of MFCs in various applications including wastewater treatment, biosensors, biohydrogen production, remote power sources, implantable medical devices, etc.

• 한국컴퓨터정보학회논문지
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• 제21권10호
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• pp.91-98
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• 2016

Outbreaks of highly contagious livestock diseases can cause direct and indirect economic impacts such as lower productivity of cattle farms, fall in tourism in damaged areas and countries, and decline in exports. They also incur tremendous social costs associated with disease elimination and restoration work. Thus, it is essential to prevent livestock diseases through monitoring and prediction efforts. Currently, however, it is still difficult to provide accurate predictive information regarding occurrences of livestock diseases, because existing cattle health monitoring or forecasting systems are only limited to monitor environmental conditions of livestock barns and check activities of cattle by using a pedometer or thermal image. In this paper, we present a biosensor-based cattle health monitoring system capable of collecting bio-signals of farm animals in an effective way. For the presented monitoring system, we design an integrated monitoring device consisting of a sensing module to measure bio-signals of cattle such as the heartbeat, the breath rate and the momentum, as well as a Zigbee module designed to transmit the biometric data based on Wireless Sensor Network (WSN). We verify the validity of the monitoring system by the comparison of the correlations of designed device with a commercial ECG equipment through analyzing the R-peak of measured signals.