• Journal of Korea Society of Industrial Information Systems
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• v.6 no.3
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• pp.95-106
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• 2001

Rapidly changing today's market requires new and innovative marketing approaches. Relationship marketing is one of the innovative marketing approaches. The key elements of the relationship marketing concept are the attraction, maintenance and enhancement of customer relationships for competitive advantage. Customer information provides the foundation for relationship marketing activities within an organization. Relationship marketing is not possible without the development and use of a database marketing system. Often the greatest obstacle in achieving advantage from relationship marketing is the development of a database marketing system. Thus, it is imperative marketers identify the characteristics necessary for successful database marketing if they hope to practice relationship marketing. A lot of researchers conclude that organizational barriers are the true, key critical issues in obtaining competitive advantage from database marketing. While Fletcher, et al. found strong evidence f the importance of organizational variables on database marketing, this area of research is largely unexplored. The objective of this research is to provide additional empirical evidence of the relationship between organizational variables and database marketing sophistication.

• Journal of the Korea Concrete Institute
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• v.17 no.5 s.89
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• pp.775-784
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• 2005

In this research, major design factors have been evaluated for the establishment of the rational seismic design code of circular RC(reinforced concrete) bridge pier Previous experimental researches have drawn a conclusion that transverse confinement reinforcements have been excessively used for RC bridge piers in Korea. Thus, the objective of this study is to propose a rational design equation for transverse reinforcements of RC bridge piers in Korea which would be classified as a low or moderate seismic region. Newly proposed equation further considers the effect of the axial force ratio and the longitudinal steel ratio. Minimum transverse confinement steel ratio is also proposed to avoid probable buckling of the longitudinal reinforcing steels subjected to relatively low axial force. It is thought that these new codes seem to alleviate the rebar congestion in the plastic hinge region of RC bridge piers which contribute to the enhancement of constructibility and economization for RC bridge construction.

• Korean Institute of Interior Design Journal
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• v.27 no.1
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• pp.58-67
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• 2018

This study aims to analyze the cases of storage space outside housing unit and propose the activation plan. The issue of storage in residential complex has continued to be reported. This is more salient due to the recent preference trend for small houses, the constant increase of living goods and the limitation of the available space inside housing unit. Although more apartment houses are trying to have individual storage in the exterior space to address these issues, there is still a paucity of the related studies and more studies are required. In this study, we conducted on-site investigation and user interview of each case to propose active usage of the storage space outside housing unit. Result of this study shows that the most crucial factor to improve is 'accessibility' in order to activate the storage space. Storage room should be located close to each household or the individual parking space. The second factor is the size and the structure of the storage room. The sufficient space for keeping and taking large objects out are required. The front of the storage room should have a clogged structure to insure privacy. The third is the provision of suitable support programs such as the system that occupants can check remotely what items are in their storage rooms, garage sale, laundry service, auto cleaning system and rental program. Those programs are required for efficient management and activation of space. Another requirement is to improve environmental factors which include maintenance of optimal temperature and humidity, automatic ventilation system, control of individual lights, and security enhancement. Based on the results of the survey, we provide basic data which can be used for practical space planning to activate exterior storage space of the housing unit. Further surveys are required to develop this study by obtaining more data for generalization.

• Journal of the Korean School Mathematics Society
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• v.1 no.1
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• pp.139-149
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• 1998

The purpose of this study is to check out whether the method that students make problems and anouence them to both students and teacher in the next class influence on the students' intersts, attitudes, logical thinking ability and lerning achievement in mathematics. The following is the experimental design and procedure. First, the author divided students into two groups. One is the experimental group and the other is the control group. These two groups' students consist of the advanced level, the intermediate level and the elementary level according to the students' learning proficiency Second, the author used the different teaching method between the experimental group and the control group. The author gave the experimental group's students the learning assignment problems according to their three levels and made students present the problems to the instructor and classmates in the next class. On the other hand, the author gave the control group's students learning assignment problems according to their three levels, and made them only submit their assingment to the instructor. The results of this study are as follows : 1)The method of solving and presenting the self-made problems on the basis of the informations to solve the given preceding model learning problems according to students' levels made students' learning attitudes more positive even though the method couldn't enhance the students' interests in mathematics. 2)The method of solving and presenting the self-made problems was effective to improve the logical thinking ability for especially the intermediate level's students among the three levels. In addition, the intermediate level's students showed great positive changes in their improvements of the learning achievment. It is assumed that this result is caused by two major factors(reasons). One is students' confidence that they can solve the fundamental problems without difficulty. And the other is students' desire to solve the problems of the intermediate level or more advanced level.

• Transactions of the Korean Society of Mechanical Engineers B
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• v.37 no.10
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• pp.887-894
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• 2013

Effective thermal conductivity of nanofluids has been predicted by using generalized self-consistent model and modified Eshelby model, which have been used for analysis of material properties of composites. A nanolayer between base fluid and nanoparticle, one of key factors for abrupt enhancement of thermal conductivity of nanofluids, is included in the analysis. The effective thermal conductivities of the nanofluid predicted by the present study show good agreement with those by models in the literature for the nanolayer with a constant or linear thermal conductivity. The predicted results by the present approach have been confirmed to be consistent with experiments for representative nanofluids such as base fluids of water or ethyleneglycol and nanoparticles of $Al_2O_3$ or CuO to be validated.

• Biomolecules & Therapeutics
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• v.15 no.2
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• pp.83-88
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• 2007

The roots of Liriope platyphylla (Liliaceae) are widely used in traditional Chinese medicine. In the present study, we investigated the effects of ethanol (70%) extract of the roots of Liriope platyphylla (ELP70) on learning and memory using behavioral and immunohistochemical methods in mice. Control animals were treated with vehicle (10% Tween 80). With sub-chronic treatments of ELP70 (p.o.) for 14 days, the latency time was significantly increased compared with that of the vehicle-treated control group (50, 100 and 200 mg/kg; P<0.05). Moreover, immunopositive cells for brain derived neurotrophic factor (BDNF) were significantly increased in the hippocapmpal dentate gyrus and CA1 regions after ELP70 treatments for 14 days (50, 100 and 200 mg/kg; P < 0.05). In addition, those cells for nerve growth factor (NGF) were also increased in the hippocapmpal dentate gyrus region (50, 100 and 200 mg/kg; P<0.05). These results suggest that the sub-chronic administration of ELP70 improves learning and memory, and that their beneficial effects are mediated, in part, by the enhancement of BDNF or NGF expression.

• 한국신재생에너지학회:학술대회논문집
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• 2007.06a
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• pp.515-518
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• 2007

Gas hydrates are ice-like crystalline compounds that form under low temperature and elevated pressure conditions. Recently, gas hydrates present a novel means for natural gas storage and transportation with potential applications in a wide variety of areas. An important property of hydrates that makes them attractive for use in gas storage and transportation is their very high gas-to-sol id ratio. In addition to the high gas content, gas hydrates are remarkably stable. The main barrier to development of gas hydrate technology is the lack of an effective mass production method of gas hydrate in solid form. In this study, some performance comparison among several cases classified by different volume sizes of solution were carried to identify the characteristics due to the volume increment. And it is found that one of the main reasons disturbing hydrate formation is related to the lack of cooling heat transfer due to the volume increase of the solution. So, three kinds of heat transfer plates which have different shapes and cross sectional areas were made and tested for the performance comparison following to the shape and area of each plate. Finally it is clarified that the heat transfer is one of the major factors effecting hydrate formation performance and the installation of heat transfer plate can enhance the formation performance especially not in terms of the quantity but the speed.

• International Journal of Industrial Entomology and Biomaterials
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• v.37 no.1
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• pp.21-28
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• 2018

CRISPR/Cas9 gene editing system is an efficient method to mutation in a sequence specific manner. Here we report the direct transfection of the Cas9 nuclease and gene specific guide RNA can be used in BM-N cell line derived from Bombyx mori ovarian tissue to enfeeble function of endogenous gene in vitro. We have used gene editing system to negative regulation components of major signaling cascade, the Toll pathway, which controls B. mori resistance to microbe infections, such as fungi and gram positive bacteria. We demonstrate that the $I{\kappa}B-like$ protein Cactus may controls the activation of transcription factors such as Rel A and Rel B. The direct transfection of Cas9 nuclease and Cactus-specific guide-RNA complex may be used in BM-N cells to disrupt the function of endogenous genes in vitro. A mutation frequency of 30-40% was observed in the transfected cells, and various mutations caused the target region. Moreover, RT-PCR analysis revealed that Cactus gene was down regulated after these mutations. More importantly, mutation of BmCactus stimulated expression of lysozyme, moricin, and lebocin genes. These results suggest that the CRISPR/Cas9 systems are expected to efficiently induce site-specific mutations and it was possible to produce antimicrobial peptide through the gene editing.

• Korean Journal of Community Nutrition
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• v.18 no.4
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• pp.354-364
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• 2013

This study was conducted to determine whether dietary factors could be related with serum adiponectin concentrations in 243, year-three female university students living in Seoul. The mean of body mass index (BMI) and adiponectin levels of all subjects were $20.17kg/m^2$ and $11.07{\mu}g/ml$, respectively. When the subjects were divided into 3 groups based on BMI (underweight: < 18.5, normal: $18.5{\leq}&lt;23$, overweight and obesity: ${\geq}23$), serum adiponectin levels in underweight group was significantly higher than that in 'normal' or 'overweight and 'obesity' groups. Also when the subjects were divided into two groups by mean adequacy ratio (MAR), serum adiponectin concentration of the high MAR group (MAR > 75) was slightly higher than that the low MAR group ($MAR{\leq}75$). Serum adiponectin levels showed a negative correlation with body weight (p < 0.01) or BMI (p < 0.001) and a positive correlation with intakes of of animal or total protein (please clarify) or vegetable protein.Among the dietary behaviors, serum adiponectin levels of females who answered 'yes' to the question about 'eating breakfast' was significantly higher than that of those who answered 'sometimes' or 'No' (p < 0.05) and serum adiponectin levels were higher among those who reported higher fruit intakes. Overall, our results suggested that healthy lifestyle including acceptable BMI, eating breakfast and higher fruit consumption might play an important role in the prevention of obesity and enhancement of blood adiponectin levels.

• The Journal of the Korea Contents Association
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• v.13 no.12
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• pp.1017-1025
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• 2013

As various types of regional festivals are contributing to the growth of local economy, promoting the culture, and enhancing the region's images, representative festivals are getting more important for local governments. This study analyzed the correlation between satisfaction on festivals' attractiveness and images of the region, based on an actual field study taken with respondants who visited 2012 Anseong World's Folkloriada Festivals. Among various facets that affect festivals' attractiveness, 4 factors such as services aside from transportation and promotional guides, programs, convenient facilities, and food significantly affected tourists' satisfaction level. Tourists' satisfaction level was found to have significant impact on the enhancement of local images. Based on these findings, this paper suggests implications and limitation of the research as well as future directions for the study.