• Journal of the Society of Cosmetic Scientists of Korea
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• v.48 no.1
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• pp.11-24
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• 2022

It has been reported that the ethanolic extract of the root of Piper methysticum (P. methysticum) inhibits melanogenesis in melanocyte stimulating hormone (MSH)-activated B16 melanoma cells. Flavokawain B (FKB) and Flavokawain C (FKC) isolated from this extract have been found to inhibit melanin production based on anti-melanogenesis activity. This study was designed to find out the inhibition and its process of FKB and FKC on melanin synthesis in melan-a melanocytes. FKB and FKC inhibited melanogenesis at 10 μM, 5 μM respectively in melan-a melanocytes. However, they did not inhibit extracellular tyrosinase activity from melan-a melanocytes. FKB reduced the protein level of tyrosinase (Tyr), tyrosinase-related protein 1 (TRP-1), tyrosinase-related protein 2 (TRP-2), microphthalmia-associated transcription factor (MITF) and the mRNA level of Tyr and TRP-1. FKC reduced the protein level of TRP-2 and MITF and the mRNA level of TRP-1 and Tyr. The reduced expression of Tyr and TRP-1 might be resulted from the decreased MITF which regulates major melanogenic proteins. However, since the mRNA expression of MITF did not change by FKB and FKC treatment, the effects of FKB and FKC on extracellular signal regulating kinase (ERK)/AKT phosphorylation, known to regulate the degradation of MITF, were confirmed. FKB and FKC significantly increased the phosphorylation of ERK1/2, not in AKT. These results suggest that FKB and FKC may be helpful as a potential depigmenting agent for various hyper-pigmentary disorders.

• The Journal of Society for e-Business Studies
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• v.27 no.1
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• pp.43-62
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• 2022

This paper is a study to analyze when ISV(independent software company) has more active participation in the platform ecosystem. According to previous studies, companies are active in technological innovation when they can appropriate the outcome of innovation and when they have complementary assets (marketing, manufacturing capabilities, etc.) that can convert the innovation into value. The effect of these two conditions to join platform ecosystem is investigated. The duplication between the ISV's product portfolio and platform service is also included as an independent variable. The two sample groups are composed of independent SW companies that signed a partner agreement with platform companies and non-participating companies in the platform. As a result of empirical study, it is found that the patent rights do not affect participation in the platform. The ISVs might have believed that the benefits from cooperation with platform companies are greater than the risks of exposure to innovative technologies and unique Biz models. On the other hand, downstream's capability and the duplication of product portfolio affect participation in the platform. If ISVs have the downstream capability to transform cooperation into value creation, ISVs are actively participating in the platform. In addition, cooperation is active when the product portfolio is complementary to platform service rather than competition. This study is the empirical study of open innovation between Korean independent software companies and digital platform companies. There are similar prior studies abroad, but there are no similar studies in Korea. It is meaningful in that the determinants of platform ecosystem participation were investigated through empirical analysis by composing a sample group of companies participating in the platform ecosystem and companies not participating in the platform ecosystem.

• Journal of the Korean Society of Marine Environment & Safety
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• v.28 no.6
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• pp.1013-1022
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• 2022

Recently, with the worldwide development of the fourth industry, the development of technologies for smart and eco-friendly ships is accelerating. With the emergence of autonomous vessels with complete unmanned or minimum personnel on board and eco-friendly fuel (methane, ammonia, electricity, etc.), the role of existing seafarers on board is expected to change significantly. To improve the competitiveness of seafarers in the future, predicting future seafarer occupation groups, improving the educational curriculum, and creating an educational system are necessary. In this study, eight occupational groups that seafarers may have in the future were derived through a review of earlier studies and brainstorming of maritime university students, incumbent seafarers and expert groups. A survey was conducted on the eight occupational groups using the Likert scale, and based on the results, a leading occupational group related to future seafarer was derived. The most likely occupational groups with high scores were remote control centre operators and cargo remote manager. In addition, essential educational elements to be educated first for these occupational groups were derived and presented.

• Journal of the Korea Society of Computer and Information
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• v.27 no.9
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• pp.1-12
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• 2022

Traditional methods of measuring corneal ulcers were difficult to present objective basis for diagnosis because of the subjective judgment of the medical staff through photographs taken with special equipment. In this paper, we propose a method to detect the ulcer area on a pixel basis in corneal ulcer images using a semantic segmentation model. In order to solve this problem, we performed the experiment to detect the ulcer area based on the DeepLab model which has the highest performance in semantic segmentation model. For the experiment, the training and test data were selected and the backbone network of DeepLab model which set as Xception and ResNet, respectively were evaluated and compared the performances. We used Dice similarity coefficient and IoU value as an indicator to evaluate the performances. Experimental results show that when 'crop & resized' images are added to the dataset, it segment the ulcer area with an average accuracy about 93% of Dice similarity coefficient on the DeepLab model with ResNet101 as the backbone network. This study shows that the semantic segmentation model used for object detection also has an ability to make significant results when classifying objects with irregular shapes such as corneal ulcers. Ultimately, we will perform the extension of datasets and experiment with adaptive learning methods through future studies so that they can be implemented in real medical diagnosis environment.

• Journal of the Korea institute for structural maintenance and inspection
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• v.26 no.6
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• pp.64-72
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• 2022

In this study, in order to confirm the seismic performance of reinforced concrete frames retrofitted with Wall Friction Damper(WFD), the test was conducted by setting two-story Reinforced concrete frames (reference specimen, OMF-N and specimen retrofitted with internal H-shaped steel frame and WFD, OMF-ALL(H)) as main variables. The WFD Seismic Retrofit Method is a mixture of strength improvement and energy dissipation methods. To prevent the pre-destruction of existing structure by friction force before sufficient energy dissipation of WFD, the internal H-shaped steel frame and chemical anchor that penetrates the side of the beam were used to install WFD. According to the test results, the OMF-N specimen showed an brittle failure pattern caused by the shear force of the R/C column after the maximum strength was expressed. The OMF-ALL(H) specimen showed that the reduction of pinching effect and the failure of the RC column occurred. Also, the maximum strength, cumulative energy dissipation and ductility of OMF-ALL(H) increased 3.01 times, 7.2 times and 1.72 times for OMF-N. As a results, test results revealed that the WFD Seismic Retrofit Method installed on Reinforced concrete structure improves the seismic performance and the strengthening effect is valid.

• Journal of the Korea institute for structural maintenance and inspection
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• v.26 no.6
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• pp.247-255
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• 2022

In this paper, a bending test was conducted on beams with two lap splice details when the effective depth of tensile high strength headed bars overlapped is the same and different. Through bending test, the lap splice performance of the high-strength headed bars was evaluated, and the applicability of the KDS-2021 design formula was evaluated. In the LS specimens with lap splice details where the high strength bars had the same effective depth, all specimens with 1.3 times or more of the development length of the KDS-2021 equation and 1 times or more of the ACI318-19 had the flexural failure mode after the ductile behavior to ensure sufficient lap splice performance. For specimens with details of lap joints between headed bars with different effective depth, when lap splice length is calculated by the KDS-2021 formula, the flexural stress may be transmitted so that the flexural strength at the cross section with the large effective depth and the cross section with the small effective depth becomes similar.

• Journal of the Korea institute for structural maintenance and inspection
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• v.26 no.6
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• pp.73-81
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• 2022

Recently, as the service life of structures increased, the load-carrying capacity of deteriorated reinforced concrete, where corrosion of reinforcing bars occurs due to various causes, is frequently decreased. In order to address this problem, many studies on the bond characteristic of FRP (Fiber Reinforced Polymer) bars with corrosion resistance, light weight and high tensile strength have been conducted, however there are not many studies on the bond characteristic of grid-typed CFRP embedded in concrete. Therefore, in order to evaluate the bond characteristics of grid-typed CFRP and its usability as a substitute for steel rebar, a pull-out test is performed using the longitudinal bond length and transverse grid length of the grid-typed CFRP as variables. Through the pull-out test, the bond load-slip curve of the grid-typed CFRP is derived, and the bond behavior is analyzed. The total bond load equation is proposed as the sum of the bond force of the longitudinal bond length and the shear force of the grid in the transverse direction. Also, expressing the area of the bond load-slip curve as total work, the change in dissipated energy with respect to the slip is analyzed to examine the effect of the tranverse grid on the bond force.

• Journal of the Korea institute for structural maintenance and inspection
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• v.26 no.6
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• pp.93-101
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• 2022

RC Slab bridges in Korea account for more than 70% of the total bridges for more than 20 years of service. As the number of aging structures increases, the importance of safety diagnosis and maintenance of structures increases. For highway bridges, cracks are a main cause of deck deterioration, which is very closely related to the decrease in bridge durability and service life. In addition, the damage rate of expansion joints and bearings accounts for approximately 73% higher than that of major members. Therefore, this study defined damage scenarios combined with devices damages and deck deterioration. The stress distribution and maximum stress on the deck were then evaluated using design vehicle load and daily temperature gradient for single and combined damage scenarios. Furthermore, this study performed damage-spread analysis and predicted condition ratings according to a deck deterioration model generated from the inspection and diagnosis history data of cracks. The heterogeneous damages combined with the member damages of expansion joints and bearings increased the rate of crack area and damage spread, which accelerated the time to reach the condition rating of C. Therefore, damage to bridge members requires proper and prompt repair and replacement, and otherwise it can cause the damage to bridge deck and the spread of the damage.

• Journal of the Korea institute for structural maintenance and inspection
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• v.26 no.6
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• pp.167-174
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• 2022

The objective of this study is to evaluate the dynamic properties of DUS (damping-up system) composed of the materials with excellent damping capacity, and to compare with those of the conventional hangar bolt. The main parameters are the type and hardness (𝜂_H), of rubber and the prestress force (value converted from the compression strain (𝜂_R) in the stress-strain relationship of rubber). The dynamic properties were examined from the natural frequency (𝜔_n), maximum response acceleration (A_m), amplification coefficient (𝛼_p), maximum relative displacement (𝚫_m), and damping ratio (𝜉_D). The test results showed that the A_m, 𝛼_p, and 𝚫_m values of DUS were 46.3%, 46.6% and 62.9% lower, respectively, and the 𝜉_D value was 3.89 times higher, when compared to those of the conventional hangar bolt. In particular, the 𝛼_p value was 1.3 for DUS, and 2.45 for the conventional hanger bolt, which were similar to those of rigid and flexible components specified in KDS 41 17 00, respectively. Consequently, in the optimal details of DUS, the 𝜂_H values of 50 and 45 were required for the NR (natural rubber) and EPDM (ethylene propylene diene monomer), and the 𝜂_R value of 5% was also recommended.

• Journal of the Korea institute for structural maintenance and inspection
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• v.26 no.6
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• pp.23-32
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• 2022

Although PSCB girder bridges account for 4% of the bridges in use on highways, they do not account for much, but 98% of PSCB girder bridges are 1^st type and 2^nd type of bridge. Also, the total length of the PSCB girder bridge is 16% (192km) of the total length of the highway bridge. Thus, the PSCB girder bridge can be one of the bridge types where maintenance is important. In order to analyze the damage types of PSCB girder bridges, a detailed analysis was conducted by selecting 62 places (477 spans) precision safety diagnosis reports considering ratio of the construction method and snow removal environment exposure class. Analysis of report and a field investigation was conducted, and as a result, most of the causes of deterioration damage were caused by rainwater (salt water) flowing into the bridge pavement soaking in between the top flange and the interface. After concrete slab deteriorate occurred then bridge pavement cracking and breaking increased and exfoliation of concrete occurred by corrosion and expansion of the reinforcing bars occurred. In addition, the cause of cracks in the longitudinal direction on the bottom of the top flange is considered to be cracks caused by restrained drying shrinkage. In conclusion, for reasonable maintenance considering the characteristics of PSCB girder bridges, it should be suggested in the design aspect that restrained drying shrinkage crack on top flange. Also, it is believed that differentiated maintenance method should be proposed according to snow removal environment exposure class.