• Journal of Institute of Control, Robotics and Systems
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• v.6 no.6
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• pp.478-485
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• 2000

A discrete event systems (DES) is a physical system that is discrete in time and state space, asynchronous (event rather than clock-driven), and in some sense generative(or nondeterministic). This paper presents the design of fifteen modular supervisors to control an experimental CIM testbed. These supervisors are nonblocking, controllable and nonconflicting. After verification of the supervisors by simulation, the supervisors for AGV system have been implemented to demonstrate their efficacy.

• Molecules and Cells
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• v.46 no.1
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• pp.65-67
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• 2023

SMILES (simplified molecular-input line-entry system) information of small molecules parsed by one-hot array is passed to a convolutional neural network called black box. Outputs data representing a gene signature is then matched to the genetic signature of a disease to predict the appropriate small molecule. Efficacy of the predicted small molecules is examined by in vivo animal models. GSEA, gene set enrichment analysis.

• Journal of Korea Entertainment Industry Association
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• v.14 no.8
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• pp.11-23
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• 2020

Many former studies for the entrepreneurial intention dealt with the opportunity-driven motivation, but the actual entrepreneurial motivation is the necessity-driven motivation such as maintaining a living. It is necessary to study the necessity-driven factors for entrepreneurship such as employment barriers and job dissatisfaction. This study focused on the fact that the majority of cultural artists are freelancers or self-employed entrepreneurs. For those who majored in culture and arts, this study was conducted to investigate how an individual's internal and external environment affects the entrepreneurial intention considering the theory of planned behavior. I explored the factors that led individuals to choose entrepreneurial intention between employment and entrepreneurship, and studied the relationship between these factors and the entrepreneurial intention. As the result of the study, the job dissatisfaction and the employment barriers were the pressure factors for entrepreneurship. Job satisfaction had a negative effect on the entrepreneurial outcome expectation and the entrepreneurial intention. The perceived employment barrier had a positive effect on the entrepreneurial outcome expectation and the entrepreneurial intention. An individual's risk-taking orientation is one of the entrepreneurship and had the positive effect on the entrepreneurial self-efficacy. The entrepreneurial outcome expectation and the entrepreneurial self-efficacy had a positive effect on the entrepreneurial intention.

• Asia-Pacific Journal of Business Venturing and Entrepreneurship
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• v.12 no.3
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• pp.135-146
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• 2017

Entrepreneurship based on valuable opportunities has a positive effect on long-term economic growth. This study examines the entrepreneurship education offered to small business entrepreneurs from the perspective of opportunity-driven entrepreneurship in order to suggest improvements and future direction for small business entrepreneurship education. Also, we tried to investigate entrepreneurial behaviors related to opportunity development more effectively by considering entrepreneurial self-efficacy and regulatory focus that play a crucial role in opportunity development process as mediating variables. Conducted was an online survey of small business owners nationwide who have completed entrepreneurship education provided by the government, and 345 online survey data were used for empirical analysis. The results show that entrepreneurship education for small business entrepreneurs positively influences entrepreneurial self-efficacy. Entrepreneurial self-efficacy is positively related to both opportunity recognition and evaluation as well as the promotion and prevention focus. Entrepreneurship education, which includes theoretically and practically oriented courses, has a positive impact on both the promotion and prevention focus. The promotion focus of small business entrepreneurs was found to have a positive effect on opportunity recognition, but not on opportunity evaluation. Also, the preventive focus of small business entrepreneurs does not have a significant effect on both opportunity recognition and evaluation. The current entrepreneurship education for small business entrepreneurs does not have a significant impact on their opportunity recognition and evaluation. These results suggest that the current entrepreneurship education for small business entrepreneurs needs improvements to promote opportunity-driven entrepreneurship.

• Fisheries and Aquatic Sciences
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• v.12 no.2
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• pp.98-103
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• 2009

The potential utility of the rockbream (Oplegnathus fasciatus) $\beta$-actin 5'-upstream sequence as a regulatory element for DNA vaccination was evaluated based on in vitro and in vivo heterologous expression assays. In the in vitro transfection experiment, the efficacy of the rockbream $\beta$-actin promoter to drive the expression of a downstream lacZ gene was significantly higher (more than fourfold) than that of the human cytomegalovirus (hCMV) promoter in two fish cell lines (grunt Haemulon plumierii fin and bluegill Lepomis macrochirus fry cell lines). In contrast, the functional activity of the rockbream $\beta$-actin promoter was hardly detectable in a mammalian mouse embryonic fibroblast cell line. Rockbream skeletal muscles injected in vivo with a GFP reporter construct driven by the $\beta$-actin promoter displayed the significantly higher expression of a GFP protein (more than threefold) than did those injected with hCMV promoter driven construct. Data from this study suggest that the homologous rockbream $\beta$-actin promoter could be used as a potential regulator for DNA vaccination in this species.

• Molecules and Cells
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• v.44 no.12
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• pp.911-919
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• 2021

The virus-induced genome editing (VIGE) system aims to induce targeted mutations in seeds without requiring any tissue culture. Here, we show that tobacco rattle virus (TRV) harboring guide RNA (gRNA) edits germ cells in a wild tobacco, Nicotiana attenuata, that expresses Streptococcus pyogenes Cas9 (SpCas9). We first generated N. attenuata transgenic plants expressing SpCas9 under the control of 35S promoter and infected rosette leaves with TRV carrying gRNA. Gene-edited seeds were not found in the progeny of the infected N. attenuata. Next, the N. attenuata ribosomal protein S5 A (RPS5A) promoter fused to SpCas9 was employed to induce the heritable gene editing with TRV. The RPS5A promoter-driven SpCas9 successfully produced monoallelic mutations at three target genes in N. attenuata seeds with TRV-delivered guide RNA. These monoallelic mutations were found in 2%-6% seeds among M₁ progenies. This editing method provides an alternative way to increase the heritable editing efficacy of VIGE.

• Asia-Pacific Journal of Business Venturing and Entrepreneurship
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• v.10 no.3
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• pp.1-13
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• 2015

Strong ties such as family members, relatives and close friends have been widely acknowledged as a vital factor when a potential entrepreneur attempts to initiate entrepreneurial activity. Recent theoretical arguments focus that family social capital, a form of social capital, that is embedded in family relationships can contribute to venture creation as well as to the development of competitive advantage for established firms. Meantime, there have been arguments that the most dominant single entrepreneurial ethnic group in the world is the Chinese people, while the People's Republic of China is widely recognized as fast growing economic power that is driven by entrepreneurial ventures in a large scale. This study tests the effect of perceived relational supports typically being provided by family members, close relatives and friends on forming self-efficacy and entrepreneurial motivation of university students by using samples collected from 4 Korean Universities(Wonkwang, Baekseok, Soongsil and Dankook university) and Guangzhou University in China. The mediating of self-efficacy was also tested to gain better understanding of the role of the variable. The results of the study suggest that 1) both self-efficacy and entrepreneurial motivation are influenced positively by the perceived relational supports, 2) self-efficacy of university students affects their entrepreneurial motivation positively, 3) self-efficacy is appeared to be mediated partially for China in between perceived relational supports and entrepreneurial motivation, but the same variable is exhibited a full mediation in the same path of the research model for Korea, which was a distinction between the students of two countries in this study. Discussion and practical implication on the results are provided.

• Journal of the Korean Mathematical Society
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• v.54 no.1
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• pp.193-213
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• 2017

We investigate an efficient approximation of solution to stochastic Burgers equation driven by an additive space-time noise. We discuss existence and uniqueness of a solution through the Orstein-Uhlenbeck (OU) process. To approximate the OU process, we introduce the Karhunen-$Lo{\grave{e}}ve$ expansion, and sparse grid stochastic collocation method. About spatial discretization of Burgers equation, two separate finite element approximations are presented: the conventional Galerkin method and Galerkin-conservation method. Numerical experiments are provided to demonstrate the efficacy of schemes mentioned above.

• Biotechnology and Bioprocess Engineering:BBE
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• v.5 no.5
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• pp.313-319
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• 2000

A crucial and causative role in the pathogenesis of atherosclerosis is believed to be the oxidative modification of low density lipoprotein (LDL). The oxidation of LDL involves released free radical driven lipid peroxidation. Several lines of evidence support the role of oxidized LDL in atherogenesis. Epidemiologic studies have demonstrated an association between an increased intake of dietary antioxidant vitamins, such as vitamin E and vitamin C and reduced morbidity and mortality from coronary artery diseases. It is thus hypothesized that dietary antioxidants may help prevent the development and progression of atherosclerosis. The oxidation of LDL has been shown to be reduced by antioxidants, and, in animal models, improved antioxidants may offer possibilities for the prevention of atherosclerosis. The results of several on going long randomized intervention trials will provide valuahle information on the efficacy and safety of improved antioxidants in the prevention of atherosclerosis. This review a evaluates current literature involving antioxidants and vascular disease, with a particular focus on the potential mechanisms.

• Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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• 2017.05a
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• pp.555-558
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• 2017

In this paper, we designed a power supply AC LED driving device which can display uniform power consumption and light efficiency even when AC power of different size is applied. By setting input voltages and deviations of different sizes, it is confirmed that the electric light characteristics are the same at two input voltages. In addition, according to peak voltage of AC power, improper lighting caused in specific LED section is improved, and LED lighting of all sections is implemented in all commercial AC input voltage.