Amid global geopolitical crises that are heightening tensions worldwide, the importance of national security is being reevaluated. Consequently, South Korea is gaining attention in the global defense market due to its superior technology, competitive pricing, and rapid delivery capabilities. The increasing international demand for defense materials offers opportunities for the development of the domestic defense industry and has the potential to lead to long-term defense strategies and an expansion of exports. In particular, the development of future advanced weapons systems and the expansion of defense exports are likely to be possible through a deep understanding of the international political and economic situation and proactive defense diplomacy. This study analyzes the impact of current global geopolitical crises on Korea's defense industry and presents effective strategies based on these findings, including innovative improvements to defense acquisition systems and the discovery of overseas defense cooperation partners to strengthen defense exports. This strategic approach aims to balance domestic consumption with exports, enhance military strength, and improve the country's standing in the international community. Therefore, efforts are needed to ensure the sustainable growth of the defense industry, enabling South Korea to achieve economies of scale and play a pivotal role in the global defense industry.
Chae-Eun YANG;Se Been KIM;Yurim JEONG;Jung-Yeon LIM
Korean Journal of Clinical Laboratory Science
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v.55
no.4
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pp.298-305
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2023
Burkitt's lymphoma is a distinct subtype of non-Hodgkin's lymphoma originating from B-cells that is notorious for its aggressive growth and association with immune system impairments, potentially resulting in rapid and fatal outcomes if not addressed promptly. Optimizing the use of Food and Drug Administration-approved medications, such as combining known safe drugs, can lead to time and cost savings. This method holds promise in accelerating the progress of novel treatments, ultimately facilitating swifter access for patients. This study explores the potential of a dual-targeted therapeutic strategy, combining the bruton tyrosine kinase-targeting drug Ibrutinib and the epidermal growth factor receptor/human epidermal growth factor receptor-2-targeting drug Lapatinib. Ramos and Daudi cell lines, well-established models of Burkitt's lymphoma, were used to examine the impact of this combination therapy. The combination of Ibrutinib and Lapatinib inhibited cell proliferation more than using each drug individually. A combination treatment induced apoptosis and caused cell cycle arrest at the S and G2/M phases. This approach is multifaceted in its benefits. It enhances the efficiency of the drug development timeline and maximizes the utility of currently available resources, ensuring a more streamlined and resource-effective research process.
Climate change has been intensifying drought frequency and severity. Such prolonged droughts reduce reservoir levels, thereby exacerbating drought impacts. While previous studies have focused on optimizing reservoir operations using historical data to mitigate these impacts, their scope is limited to analyzing past events, highlighting the need for predictive methods for future droughts. This research introduces a novel approach for predicting minimum inflow at the Seomjingang dam which has experienced significant droughts. This study utilized the Stochastic Analysis Modeling and Simulation (SAMS) 2007 to generate inflow sequences for the same period of observed inflow. Then we simulate reservoir operations to assess firm yield and predict minimum inflow through synthetic inflow analysis. Minimum inflow is defined as the inflow where firm yield is less than 95% of the synthetic inflow in many sequences during periods matching observed inflow. The results for each case indicated the firm yield for the minimum inflow is on average 9.44 m3/s, approximately 1.07 m3/s lower than the observed inflow's firm yield of 10.51 m3/s. The minimum inflow estimation can inform reservoir operation standards, facilitate multi-reservoir system reviews, and assess supplementary capabilities. Estimating minimum inflow emerges as an effective strategy for enhancing water supply reliability and mitigating shortages.
Offshore wind power generation has significant advantages, including enhanced energy security and job creation. However, despite these benefits, South Korea has not fully utilized its potential in this sector. In contrast, offshore wind power industry development in Europe has been driven by government leadership. Drawing from this experience, South Korea also needs to relax regulations, strengthen necessary infrastructure, and enhance financial support systems to activate the offshore wind power industry. For this, sustained government leadership is absolutely essential. Without addressing the capacity issues in the power grid, we cannot expect offshore wind power generation to succeed. To address grid issues, we propose the enactment of a special law called the "Special Act on Grid Expansion." Considering KEPCO's financial situation, private investment should be encouraged for grid construction. The role of developers is crucial for the successful development and operation of offshore wind power. They manage risks throughout various stages, from site acquisition to construction and operation, which have a significant impact on the success or failure of projects. Since domestic developers currently lack experience in offshore wind power, a cooperative strategy that leverages the experience and technology of advanced countries is necessary. Energy issues should be recognized as important tasks beyond mere political ideologies, as they are crucial for the survival of the nation and its development. It is essential to form a public consensus and implement ways for residents to coexist with offshore wind power, along with the conservation of marine ecosystems and effective communication with stakeholders. Expansion of the offshore wind power industry requires support in various areas, including financial and tax incentives, technology research investment, and workforce development. In particular, achieving carbon neutrality by 2050 necessitates the activation of offshore wind power alongside efforts by major corporations to transition to renewable energy. South Korea, surrounded by the sea, holds significant offshore wind power potential, and it is our responsibility to harness it as a sustainable energy source for future generations. To activate the offshore wind power market, we need to provide financial and tax support, develop infrastructure and research, and foster a skilled workforce. As major corporations transition to renewable energy to achieve carbon neutrality by 2050, offshore wind power must play a significant role. It is our responsibility to fully utilize South Korea's potential and make offshore wind power a new driver of growth.
The susceptibility of Aphis gossypii populations collected from three fields (WJ, CC, and GS) was evaluated to three insecticides (afidopyropen, chlorfenapyr and cyantraniliprole) and three binary mixtures. Three field populations showed resistance ratios of over 100 to all insecticides. The Combination Index (CI), %M(synergism), Co-Toxicity Coefficient (CTC), Wadley Ratio (WR), Synergism Ratio (SR) and Abbott Ratio (AR) were used to evaluate combined effect of the insecticides. Afidopyropen + chlorfenapyr (CI ≤ 0.16; %M(synergism) ≥ 94; CTC ≥ 764.5; WR ≥ 6.4; SR ≥ 6.9 and AR ≥ 1.1) showed a synergism in all filed populations. WJ and CC populations showed a synergism in all binary mixtures of insecticides, but GS population showed an antagonism for chlorfenapyr + cyantraniliprole (CI, 1.63; %M(synergism), 30; CTC, 64.0; WR, 0.6 and AR, 0.54) and afidopyropen + cyantraniliprole (CI, 6.7; %M(synergism), 1; CTC, 19.8; WR, 0.2 and AR ≤ 0.55). All mixtures (afidopyropen + chlorfenapyr, chlorfenapyr + cyantraniliprole and afidopyropen + cyantraniliprole) showed a control value of over 99% after 21 days of treatment in the field. This study highlights that binary mixtures of three insecticides serve as an effective control strategy for A. gossypii.
Korean Journal of Construction Engineering and Management
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v.25
no.2
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pp.3-10
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2024
The purpose of this study is to analyze the effects of smart construction equipment applied at the construction site of the first smart city in the Korea and derive an application strategy for the utilization of smart construction equipment. To achieve this, aythors examined the practical effects and issues of safety systems and construction systems utilizing machine guidance (MG) technology, which is a representative smart construction equipment used in civil engineering construction sites. Both the MG safety system and MG construction system were found to be sufficiently effective in improving construction productivity. However, there are challenges that need to be addressed, such as the approval process for work results using MG systems, system changes due to frequent replacement of on-site equipment, and usability improvements for elderly on-site workers. The study presented some solutions that have been implemented on-site to address these issues. The utilization effects and issues presented in the study were analyzed through direct feedback from workers and managers who have utilized the MG technology on-site for a considerable period of time. These results can be used as preliminary data for the similar construction projects, considering the limited availability of empirical analysis data for equipment automation.
Sewon Oh;Byeonghyeon Yun;Se Hee Kim;Sang-Yun Cho;Namhee Jung;Kyung Ran Do;Kang Hee Cho;Hyun Ran Kim
Korean Journal of Plant Resources
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v.37
no.3
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pp.263-269
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2024
Embryos of early-ripening peaches could not achieve physiological maturation or undergo abortion before harvest. Embryo rescue is an effective strategy to rescue embryos from early-ripening peaches. Thus, the current study was carried out to determine the appropriate developmental stage and optimal medium composition for embryo rescue in early-ripening peach. Development of open-pollinated 'Yumi' fruit was investigated from 20 to 90 days after full bloom (DAFB) to explore period occurring endocarp hardening. After endocarp hardening, embryo development was observed by light microscopes. Shoot and root meristems were observed at 65 DAFB and embryo size rapidly increased at 75 DAFB. Embryos collected at 75, 80, 85, and 90 DAFB were cultured on four media based on Driver and Kuniyuki (DKW) medium. Germination rate of embryos cultured on four media gradually increased from 75 to 90 DAFB and reached 100% at 90 DAFB. Notably, M3 medium (0.5 DKW supplemented with 6-benzylaminopurine (BAP) 1.0 ㎎/L) displayed the highest germination rate at 75 and 80 DAFB stages. Growth and development of shoot and root were pronounced in plantlet cultured at 90 DAFB stage. While delayed shoot growth was evident in plantlets cultured at 75, 80, and 85 DAFB stages, this retardation could be overcome through the application of growth regulators, particularly in M3 and M4 (0.5 DKW supplemented with BAP 1.0 ㎎/L and indole-3-butyric acid 0.5 ㎎/L) media. Remarkably, roots of plantlet grown in M4 medium exhibited limited elongation. In conclusion, germination rate of embryo and growth of embryo cultured plantlet can be enhanced by collecting seeds from early-ripening 'Yumi' at the 90 DAFB stage and conducting embryo culture using the M3 medium.
Hassan Ali Al-Ababneh;Ainur Osmonova;Ilona Dumanska;Petro Matkovskyi;Andriy Kalynovskyy
International Journal of Computer Science & Network Security
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v.24
no.7
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pp.128-142
/
2024
Creation and implementation of export-oriented strategy is an urgent issue of economic development of any country. In an export-oriented model of economic development, exports should be a means of promoting economic growth and a tool to strengthen existing and potential competitive advantages. Agricultural production is the key factor in exports and the source of foreign exchange earnings in many countries. However, the export potential of agricultural producers may be inefficiently fulfilled due to the heterogeneity of countries in terms of economic development, trade relations and border policy. The aim of the research is to study the nature, main trends and problematic aspects of fulfilling the export potential of agricultural production in the context of aggravating food crisis. The study involved general scientific methods (induction and deduction, description, analysis, synthesis, generalization) and special (statistical method, economic analysis, descriptive statistics and interstate comparisons, graphical method). The need to ensure food security by countries around the world urges the importance of the agricultural sector as a catalyst for economic development, sources of foreign exchange earnings, investment direction, etc. The study of agricultural specialization led to the conclusion that wheat and sugar are goods with the highest export potential. It is substantiated that the countries of South America, OECD, North America and Europe have the highest level of realization of export potential of agricultural production, and African countries are import-dependent. In addition, the low export orientation of Africa and Asia due to the peculiarities of their natural and climatic conditions is established based on the assessment of export-import operations in the regional context. The internal and external export potential of each of the regions is analysed. Economic and mathematical simulation of assessing the impact of the most important factors on the wheat exports volumes was applied, which allowed predicting wheat exports volume and making sound management decisions regarding the realization of the export potential of agricultural companies. The inverse correlation between the exports volume and wheat consumption per capita, and the direct correlation between the effective size and area of land used for wheat cultivation was established through the correlation and regression analysis.
Journal of Cerebrovascular and Endovascular Neurosurgery
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v.25
no.4
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pp.411-419
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2023
Objective: Optochiasmatic cavernoma is an extremely rare cerebral lesion. They account for approximately 1% of all cavernomas of the central nervous system. Reports on this pathology are limited. Abrupt visual deterioration is a common symptom of the disease. Treatment strategy and visual outcomes after different treatment approaches remain a subject for discussion. Methods: Patients operated in a period 2005-2021 were analyzed in this study. All patients preoperatively underwent computed tomography (CT) scan, CT-angiography, and magnetic resonance imaging (MRI). Visual function of the patients was assessed pre-op, post-op and at the follow-up. Duration of visual dysfunction was noted as well. Surgical details were also extracted from medical notes. All patients were followed up, and control MRI was performed one month after operation. We assessed surgical series of optochiasmatic cavernomas published for last 10 years. Further comparative analysis with our data was performed. Results: Five patients were included into this study. There were four men and one woman. Mean age comprised 33.8 years (range 20-48 years). Most patients were admitted to our hospital due to visual disturbances (80%). Visual function improved in four patients. Visual function was unchanged in one patient, lacking visual distur-bancies pre-op. Complication developed in one patient. Conclusions: Optochiasmatic cavernomas are encountered extremely rare. Despite the use of contemporary diagnostic options, differential diagnosis remains challenging. Full diagnostic work-up is mandatory. After the diagnosis is made, surgical treatment should be considered first. Total microsurgical or endoscopic transsphenoidal removal of the optochiasmatic cavernoma is a relatively safe and effective treatment method facilitating improvement of visual function.
Recently, domestic universities have become more competitive among universities due to the Fourth Industrial Revolution and the rapid decline of population. As a result, universities are making great efforts to improve university service quality to enhance university competitiveness as they change from supplier-centered thinking to consumer-centered thinking. Despite the increasing importance of university service quality, research on service quality is mainly focused on companies, and research on service quality in the university education environment is insufficient. Therefore, this study aims to examine the influence relationship between university service quality, trust, reputation, and behavior intention. The results of this study are as follows. First, among the service quality of university, tangibility, assurance, and empathy were found to have a positive (+) effect on the trust of the university, but reliability was found to have no significant effect on the trust of the university. Second, among the service quality of university, tangibility, reliability, and empathy were found to have a positive (+) effect on the reputation of the university, but assurance was found to have no significant effect on the reputation of the university. Third, it was found that the trust of the university had a positive (+) effect on the behavior intention. Fourth, it was found that the university's reputation had a positive (+) effect on the behavior intention. Through the above research results, this study aims to derive an effective management plan for university service quality and to present a plan for establishing a differentiated operating strategy for universities that can respond to students' learning needs and changes in the times in the rapidly changing university education environment.
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