• 한국심리학회지:학교
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• 제17권2호
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• pp.199-222
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• 2020

이 연구는 사회부과적 완벽주의가 불확실성에 대한 인내력 부족과 반추적, 반성적 반응양식을 매개로 우울에 미치는 영향을 검증하여 대학생에게 나타나는 우울을 효과적으로 해결할 수 있는 방안을 모색하고자 실시하였다. 이를 위해 중부권 소재의 대학에 재학중인 대학생 283명을 대상으로 우울(CES-D), 다차원적 완벽주의 척도(HMPS), 불확실성에 대한 인내력 부족 척도(IUS), 우울 기분에 대한 반응양식 척도(RDQ)를 사용하여 설문을 실시하였다. 연구 결과는 다음과 같다. 첫째, 사회부과적 완벽주의 불확실성에 대한 인내력 부족, 반추적 반응양식은 정적인 상관이 나타났지만 반성적 반응양식과는 상관이 나타나지 않았다. 둘째, 사회부과적 완벽주의가 우울에 영향을 미치는 과정에서 불확실성에 대한 인내력 부족을 1차 매개변인으로 설정하고 반추적 반응양식을 2차 매개 변인으로 설정하여 관계를 검증하였고, 모든 매개효과는 의미있는 수준이었다. 한편 2차 매개변인을 반성적 반응양식으로 설정하여 매개효과를 검증한 결과 매개효과는 유의하지 않았다. 이러한 결과로 볼 때 사회부과적 완벽주의로 나타나는 우울을 예방하기 위해서는 불확실성에 대한 인내력 부족과 반추적 반응양식에 초점을 두어 개입한다면 유용할 수 있을 것이다. 마지막으로 결과를 바탕으로 연구의 의의 및 한계점을 논의하였다.

• 한방안이비인후피부과학회지
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• 제21권2호
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• pp.28-38
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• 2008

In traditional oriental medicine, Gentianae Radix has been used clinically for clearing away 'heat', removing dampness and purging fire in the liver and gall bladder. However, there has been a lack of studies regarding the effects of Gentianae Radix on the immunological activities. The present study was conducted to evaluate the effect of Gentianae Radix on the regulatory effects of cytokines and nitric oxide(NO) for the immunological activities in Raw 264.7 cells. After the treatment of Gentianae Radix MeOH extract, cell viability was measured by MTT assay, and NO production was monitored by measuring the nitrite content in culture medium. The expression of COX-2 and iNOS was determined by immunoblot analysis, and the content of levels of cytokines in media was analyzed by ELISA kit. Results provided evidence that Gentianae Radix inhibited the production of nitrite and nitrate (NO), inducible nitric oxide synthase (iNOS), $interleukin-l{\beta}$ $(IL-l{\beta})$ and IL-6, and the activation of phospholylation of inhibitor ${\kappa}B{\alpha}$ ($p-I {\kappa}B{\alpha}$) in Raw 264.7 cells activated with lipopolysaccharide (LPS). These findings suggest that Gentianae Radix can make anti-inflammatory effect, which may playa role in adjunctive therapy.

• IMMUNE NETWORK
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• 제8권1호
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• pp.13-20
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• 2008

Background: Coptis chinensis rhizome has been used as a medicinal herb in traditional Oriental medicine. We investigated the effects of Coptis chinensis extract on inflammatory mediators and delayed type hypersensitivity in mice. Methods: The inhibitory effect of ethanolic extract of Coptis chinensis (CCE) on cell proliferation was evaluated using MTS assay. The lipopolysaccharide (LPS)-stimulated RAW264.7 macrophages and the Con A-activated mouse splenocytes were cultured with various concentrations of CCE. Total nitric oxide (NO) production was determined by Griess reaction. The amounts of secreted prostaglandine E2 ($PGE_2$), interleukin (IL)-2 and IFN-${\gamma}$ were measured by ELISA. To investigate the in vivo anti-inflammatory effect of CCE, oxazolone-induced delayed type hypersensitivity (DTH) model was used. Results: The CCE at $100{\mu}g/ml$ significantly blocked the LPS-induced production of pro-inflammatory mediators (NO and PGE) in RAW264.7 macrophages. Also, it significantly inhibited cell proliferation and cytokine (IL-2 and IFN-${\gamma}$) production in splenocytes. Furthermore, when splenocytes from CCE fed mice (200 mg/kg for 2 weeks) were activated with Con A, cell proliferation and cytokine production were significantly inhibited. In addition, CCE decreased in vivo inflammation in oxazolone-induced DTH model mice. Conclusion: We suggest that Coptis chinensis can be used as an anti-inflammatory drug by exerting an inhibitory effect in inflammatory mediator- and cell-mediated inflammation.

• 대한본초학회지
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• 제23권3호
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• pp.11-18
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• 2008

SunBangHwalMyungEum (SBH) has the effects of subduing swelling, resolving masses and alleviating pain in traditional oriental medicine. Recent studies showed that SunBangHwalMyungEum produced anti-cancer, anti-metastasis and immuno-modulatory effects. However there is lack of studies regarding the effects of SBH on the immunological activities. The present study was conducted to evaluate the effect of SBH on the regulatory mechanism of cytokines and nitric oxide (NO) in Raw 264.7 cells. Methods : After the treatment of SBH, cell viability was measured by MTT assay, NO production was monitored by measuring the nitrite content in culture medium. Inducible nitric oxide synthase (iNOS) was determined by immunoblot analysis, and levels of cytokine were analyzed by sandwich immunoassays. Results : Results provided evidence that SBH inhibited the production of NO, iNOS, $interleukin-1{\beta}$ ($(IL-1{\beta})$), IL-6, and the activation of phospholylation of inhibitor ${\kappa}B{\alpha}$ in Raw 264.7 cells activated with lipopolysaccharide. Conclusions : These findings suggest that SBH can produce anti-inflammatory effect, which may play a role in adjunctive therapy in Gram-negative bacterial infections.

• 한국융합학회논문지
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• 제7권4호
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• pp.163-172
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• 2016

본 연구는 부모-자녀 의사소통이 스트레스 정도, 자기통제력, 자기 효능감을 매개로 하여 스마트폰 중독에 미치는 영향에 관한 융합연구이다. J도와 K도 소재 대학생들을 대상으로 시행하였으며 232부의 설문지를 분석 자료로 사용하였다. 분석 결과 스마트폰 중독은 부모-자녀 의사소통, 자기통제력, 자기효능감과는 각각 (-)의 상관관계가 있었고, 스트레스 정도와는 (+)의 상관관계가 있었다. 또한, 부모-자녀 의사소통은 스트레스 정도, 자기통제력, 자기효능감을 매개로 하여 스마트폰 중독에 영향을 미치고 있는 것으로 나타났다. 따라서 대학생의 스마트폰 중독을 감소시키기 위해서는 부모-자녀 의사소통을 원활히 하기 위한 프로그램의 개발과 시행이 체계적으로 이루어져야 할 것이며, 스트레스 감소 및 자기통제력과 자기효능감 수준을 높이기 위한 방안이 필요하다.

• 한국사회복지학회:학술대회논문집
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• 한국사회복지학회 2005년도 춘계학술대회자료집
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• pp.677-702
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• 2005

The purpose of this study is to examine the Korean social workers' level of social work values, advocacy attitude and advocacy intervention, and to verify the relations among social work education, social work advocacy and social work values by examining whether social work education influences social work advocacy and social work values, and whether social work values affect social work advocacy. Further, this study wishes to confirm not only the direct effect that social work education has on social work advocacy, but also how social work education indirectly influences social work advocacy through social work values on the social level as a mediator. The research of this study was conducted on 461 social work practitioners who have obtained either social worker licenses or mental health social worker licenses and are currently working in the field. As survey tools, this study utilized social work advocacy attitude, social work advocacy intervention, outcomes of social work education, social work values, self-esteem and locus of control. Collected data were analyzed by using SPSS/PC+ 11.5 for one-way ANOVA and t-test, Pearson's correlation, reliability analysis, exploratory factor analysis and multiple regression. To sum up the results of the study in terms of the research hypothesis, the research hypothesis was established according to the analysis method of the testing mediation of Baron & Kenny (1986) in order to examine whether social work values on the social level intervene between social work education and social work advocacy. The results of the hypothesis test confirm that social work values on the social level serve as a mediator variable.

• 한국조리학회지
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• 제22권6호
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• pp.33-51
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• 2016

The hotel industry needs to make the competitive advantage difficult to be imitated in order to remain sustainable in competitive business circumstances. Front-line employees' service-oriented citizenship behaviors(OCBs) can be such a strength from the perspective of organizational system. With an aim of investigating the antecedents of the hotel front-line employees' service-oriented OCBs, this study proposed a theoretical framework linking authentic leadership to service-oriented OCBs with goal commitment as a mediator. A total of 260 cases without missing values have been used for the final analysis and structural equation modeling (SEM) is employed using the SPSS and AMOS 7. It was first found that self-awareness and relational transparency of authentic leadership made a significant impact on their goal commitment while balanced processing and moral perspective failed to influence them. Second. goal commitment influenced all sub-factors of service-oriented OCBs. Third, moral perspective and relational transparency of authentic leadership significantly influenced service-oriented OCBs while self-awareness and relational transparency failed to make it. Finally, goal commitment significantly makes an intervening effect for the relationship between self-awareness & service-oriented OCBs and relational transparency & service-oriented OCBs but failed to intervene the other relationships. The results provide theoretical and practical implications regarding directions of leadership styles and HR management in the hotel industry and suggestions for the further extended studies.

• 가정과삶의질연구
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• 제29권3호
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• pp.59-69
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• 2011

The purpose of this study was to investigate the structural relationships among adolescents' internet addiction, self-esteem, self-control, and aggression. The participants were 300 students in their first year of middle school. The questionnaire consisted of measures of internet addiction, self-esteem, self-control, and aggression. The major findings were as follows: 1) self-control had a direct effect on aggression; 2) internet addiction had a direct effect on self-esteem and self-control; 3) self-esteem had a direct effect on self-control; 4) internet addiction had an indirect effect on aggression and self-control; and self-esteem had an indirect effect on aggression. This study implied that self-related variables could mediate the relationship between the possibility of internet addiction and adolescents' aggression. This study also suggested that research on various mediator variables could reduce adolescents' psychosocial problems.

• The Journal of Asian Finance, Economics and Business
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• 제7권11호
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• pp.967-976
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• 2020

This study aims to improve knowledge of consumers' decision-making by testing a conceptual model that considers the hotel's service quality and service value toward customers' behavioral intentions using a mediator, which is the role of consumers' satisfaction. The object of this research is five-star hotels, which has become a significant segment of the general hotel industry and is undergoing rapid expansion. This research is a quantitative research using questionnaire as the sampling method answered by people who have stayed at five-star hotels before. The total of 150 valid respondents were used in this study. The collected data was processed by a statistical tool software, Partial Least Square (PLS). The major findings of this research showed that the relations between service quality and service value of five-star hotels do not have significant positive impact on consumers' behavioral intention, nonetheless the mediation analysis shows that customers' satisfaction partially mediates service quality and service value with consumers' behavioral intentions to stay. It means that in this case, consumers' satisfaction has an important role to mediate service value quality and service value. As a result, the study shows that four out of six hypotheses are supported. A couple of recommendations are suggested for further research.

• 한국학교보건학회지
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• 제31권1호
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• pp.29-38
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• 2018

Purpose: The purpose of this study is to investigate the mediator effect of major satisfaction in relation to depression and job-seeking stress of university students according to the majors. Methods: This descriptive study was conducted in three universities randomly chosen from 47 universities in Seoul, Korea. Participants were 241 undergraduate students who were eligible and agreed to participate in the study. Data were collected from October 27 to November 10, 2014. The data were analyzed with descriptive statistics, $x^2$ test, Fisher's exact test, t-test, Kruskal-Wallis test, Pearson correlation coefficients, simple and multiple regression techniques with the PASW/WIN 20.0 program. Results: There were significant negative, negative, and positive correlations between job-seeking stress and major satisfaction, major satisfaction and depression, and job-seeking stress and depression regardless of major field, respectively. Moreover, in the major group in natural science and engineering, the link between job-seeking stress and depression was partially mediated by major satisfaction. Conclusion: The findings of this study contribute to providing basic data for the development of job-seeking stress and depression intervention programs and future study for university students.