• Journal of Welding and Joining
• /
• v.24 no.1
• /
• pp.43-49
• /
• 2006

This paper describes the friction surface modification which has been successfully developed with the friction stir welding recently There are several problems including just position control and backlash in conventional friction surface modification system. Therefore it has been developed the friction surface modification system which has been controlled precisely both position and force by driving hydraulic cylinder in this paper. The mechtrode rotation speed(N) and feeding speed(Vz), travel speed(Vx,y) are of critical importance for the width and thickness of the coating in friction surfacing process. But there is no theoretical method of determining interrelations between process parameters affect the coating width and thickness. As a result of DOE(design of experiment) with developed system, the coating thickness and width seemed to decrease according to increase the mechtrode rotation speed(N) and traveling speed(Vx,y), to decrease feeding speed(Vz) apparently. However as the result of regression analysis the main effect was only the mechtrode rotation speed in the coating thickness.

• Korean Journal of Metals and Materials
• /
• v.46 no.5
• /
• pp.304-309
• /
• 2008

Magnesium alloys containing $Mg_2Si$ particles, as a promising cheap heat-resistant magnesium alloy for automobile power train parts applications, are attracting more attention of both material scientists and design engineers. Modification of the Chinese script shape $Mg_2Si$ particle is a key for using this alloy in sand or permanent mould casting. In the present work, the modification effect of Sr and Sb on the corrosion properties of the Mg-5Al-2Si alloy was investigated. Sr or Sb addition promoted the formation of fine polygonal shape $Mg_2Si$ particles by providing the nucleation sites. Sr was more effective element than Sb for shape modification of Chinese script shape $Mg_2Si$. Such improved microstructure of the modified alloy resulted in large improvement in corrosion resistance as compared to unmodified Mg-5Al-2Si alloy.

• BMB Reports
• /
• v.28 no.2
• /
• pp.124-128
• /
• 1995

Biodegradative threonine dehydratase purified from Serratia marcescens ATCC 25419 was inactivated by the arginine specific modification reagent, phenylglyoxal (PGO) and the lysine modification reagent, pyridoxal 5'-phosphate (PLP). The inactivation by PGO was protected by L-threonine and L-serine. The second order rate constant for the inactivation of the enzyme by PGO was calculated to be 136 $M^{-1}min^{-1}$. The reaction order with respect to PGO was 0.83. The inactivation of the enzyme by PGO was reversed upon addition of excess hydroxylamine. The inactivation of the enzyme by PLP was protected by L-threonine, L-serine, and a-aminobutyrate. The second order rate constant for the inactivation of the enzyme by PLP was 157 $M^{-1}min^{-1}$ and the order of reaction with respect to PLP was 1.0. The inactivation of the enzyme by PLP was reversed upon addition of excess acetic anhydride. Other chemical modification reagents such as N-ethylmaleimide, 5,5'-dithiobis (2-nitrobenzoate), iodoacetamide, sodium azide, phenylmethyl sulfonylfluoride and diethylpyrocarbonate had no effect on the enzyme activity. These results suggest that essential arginine and lysine residues may be located at or near the active site.

• Membrane and Water Treatment
• /
• v.4 no.2
• /
• pp.109-126
• /
• 2013

Surface modification by low-pressure ammonia ($NH_3$) plasma on commercial thin-film composite (TFC) membranes was investigated in this study. Surface hydrophilicity, total surface free energy, ion exchange capacity (IEC) and zeta (${\zeta}$)-potentials were determined for the TFC membranes. Qualitative and quantitative analyses of the membrane surface chemistry were conducted by attenuated total reflectance Fourier transform infrared (ATR FT-IR) spectroscopy. Results showed that the $NH_3$ plasma treatment increased the surface hydrophilicity, in particular at a plasma treatment time longer than 5 min at 50 W of plasma power. Total surface free energy was influenced by the basic polar components introduced by the $NH_3$ plasma, and isoelectric point (IEP) was shifted to higher pH region after the modification. A ten (10) min $NH_3$ plasma treatment at 90 W was found to be adequate for the TFC membrane modification, resulting in a membrane with better characteristics than the TFC membranes without the modification for water treatment. The thin-film chemistry (i.e., fully-aromatic and semi-aromatic nature in the interfacial polymerization) influenced the initial stage of plasma modification.

• Journal of the Earthquake Engineering Society of Korea
• /
• v.23 no.4
• /
• pp.201-209
• /
• 2019

Response modification factors of school facilities for non-seismic RC moment frames with partial masonry infills in 'Manual for Seismic Performance Evaluation and Retrofit of School Facilities' published in 2018 were investigated in the preceding study. However, since previous studies are based on 2D frame analysis and limited analysis conditions, additional verification needs to be performed to further apply various conditions including orthogonal effect of seismic load. Therefore, this study is to select appropriate response modification factors of school facilities for non-seismic RC moment frames with partial masonry infills by 3D frame analysis. The results are as follows. An appropriate response modification factor for non-seismic RC moment frames with partial masonry infills is proposed as 2.5 for all cases if the period is longer than 0.6 seconds. Also if the period is less than 0.4 seconds and the ratio of shear-controlled columns is less than 30%, 2.5 is chosen too. However, if the period is less than 0.4 seconds and the ratio of shear-controlled columns is higher than 30%, the response modification factor shall be reduced to 2.0. If the period is between 0.4 and 0.6 seconds, then linearly interpolates the response correction factor.

• Transactions of the Korean Society of Mechanical Engineers B
• /
• v.24 no.2
• /
• pp.224-232
• /
• 2000

Four turbulent $k-{\varepsilon}$ models (i.e., standard model, modified models with streamline curvature modification and/or preferential dissipation modification) are applied in order to analyze the turbulent flow of wall-attaching offset jet. For numerical convergence, this paper develops a method of slowly increasing the convective effect induced by skew-velocity in skew-upwind scheme (hereafter called Partial Skewupwind Scheme). Even though the method was simple, it was efficient in view of convergent speed, computer memory storage, programming, etc. The numerical results of all models show good prediction in first order calculations (i.e., reattachment length, mean velocity, pressure), while they show some deviations in ·second order (i.e., kinetic energy and its dissipation rate). Like the previous results obtained by upwind scheme, the streamline curvature modification results in better prediction, while the preferential dissipation modification does not.

• Proceedings of the Korea Concrete Institute Conference
• /
• 2001.05a
• /
• pp.859-864
• /
• 2001

For earthquake resistance design, a response modification factor is used to reduce the design strength and it reflects ductility, reserve strength, redundancy and damping effect. But this factor has not theoretical basis. In this study, two response modification factors are compared and analyzed for shear wall apartment building.; the one is introduced by ATC-19 Procedures, the other is suggested FEMA-273 and ATC-40 through nonlinear static analysis. For the results, ATC-19 procedure gives a reasonable estimation to R factor. But $R_{u}$ by using FEAM-273 and ATC-40 methods is estimated so small in case of a minor or moderate earthquake region. Due to this fact, response modification factor is smaller than suggested load criterion 3.0. So, it needs to decrease wall volume and reduce the global strength and system stiffness for proper ductile behavior matching to domestic load criterion.

• Proceedings of the Korean Society of Precision Engineering Conference
• /
• 2002.05a
• /
• pp.1059-1062
• /
• 2002

In this paper, after we make high speed gear requested high precision, we got data on the sound level is Max 60,000rpm for tooth modification. We make a decision about tooth modification after predicting exactly amount of tooth interference by FEM. The purpose of this research is that modified gear is to drive under stable sound level. To accomplish its, Beam elements are used to simulate the same condition as a real gear drive by FEM. From result of simulation and experiment, if it has holes to decrease whole weight of high speed gear, it is not good effect because it has much more deformation than not.

• BMB Reports
• /
• v.43 no.10
• /
• pp.649-655
• /
• 2010

Alzheimer's disease (AD) is the most common age-dependent neurodegenerative disorder and shows progressive memory loss and cognitive decline. Intraneuronal filaments composed of aggregated hyperphosphorylated tau protein, called neurofibrillary tangles, along with extracellular accumulations of amyloid $\beta$ protein (A$\beta$), called senile plaques, are known to be the neuropathological hallmarks of AD. In light of recent studies, epigenetic modification has emerged as one of the pathogenic mechanisms of AD. Epigenetic changes encompass an array of molecular modifications to both DNA and chromatin, including transcription factors and cofactors. In this review, we summarize how DNA methylation and changes to DNA chromatin packaging by post-translational histone modification are involved in AD. In addition, we describe the role of SIRTs, histone deacetylases, and the effect of SIRT-modulating drugs on AD. Lastly, we discuss how amyloid precursor protein (APP) intracellular domain (AICD) regulates neuronal transcription. Our understanding of the epigenomes and transcriptomes of AD may warrant future identification of novel biological markers and beneficial therapeutic targets for AD.

• ETRI Journal
• /
• v.39 no.1
• /
• pp.76-86
• /
• 2017

In this study, we propose an automatic contrast enhancement method based on transfer function modification (TFM) by histogram equalization. Previous histogram-based global contrast enhancement techniques employ histogram modification, whereas we propose a direct TFM technique that considers the mean brightness of an image during contrast enhancement. The mean point shifting method using a transfer function is proposed to preserve the mean brightness of an image. In addition, the linearization of transfer function technique, which has a histogram flattening effect, is designed to reduce visual artifacts. An attenuation factor is automatically determined using the maximum value of the probability density function in an image to control its rate of contrast. A new quantitative measurement method called sparsity of a histogram is proposed to obtain a better objective comparison relative to previous global contrast enhancement methods. According to our experimental results, we demonstrated the performance of our proposed method based on generalized measures and the newly proposed measurement.