• Molecules and Cells
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• 제40권11호
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• pp.864-870
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• 2017

The uncoupling protein 4 (ucp-4) gene is involved in age-dependent neurodegeneration in C. elegans. Therefore, we aimed to investigate the mechanism underlying the association between mitochondrial uncoupling and neurodegeneration by examining the effects of uncoupling agents and ucp-4 overexpression in C. elegans. Treatment with either DNP or CCCP improved neuronal defects in wild type during aging. Uncoupling agents also restored neuronal phenotypes of ucp-4 mutants to those exhibited by wild type, while ucp-4 overexpression attenuated the severity of age-dependent neurodegeneration. Neuronal improvements were further associated with reductions in mitochondrial membrane potentials. However, these age-dependent neuroprotective effects were limited in mitophagy-deficient mutant, pink-1, background. These results suggest that membrane uncoupling can attenuate age-dependent neurodegeneration by stimulating mitophagy.

• 동아시아식생활학회지
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• 제18권3호
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• pp.322-330
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• 2008

This study was performed to the possibility of developing anti-aging convenient food that is to Koreans' taste. Editor: this abstract appears to describe a study of public opinion and not related to the development of anti-aging convenient foods. In total, The 150 adults, living in Seoul (Korea), participated in this study in the capacity of subjects. Editor: You really have to mention the age-range of the subjects, as senility is an old age disease. In particular, you talk about the intention of subjects (discussed below) to buy anti-aging food products. This would be directly related to their age, as I assume that older people would be more concerned about senility that relatively younger subjects. They were randomly assigned to 25 groups. In result initial descriptive analysis revealed that, 82 percent of subjects awoke to were aware of senility, and the while 26.7 percent were seriously thought of it concerned. Furthermore, The 58.7 percent said that believed food has the possibility has a role in of controlling senility, and the while 64.0 percent said stated that senility may be controlled by eating constitutional foods. Further comparative analysis of In the case of the group of which members subjects have been who were trying to control senility revealed that their, the reliance on food general and constitutional food was significantly higher than those who have not tried to do so did nothing. The From the 61.3 percent have been of subject who were trying to control senility, from among them, the 74.0 percent and the 22.7 percent were relied on physical taking exercises and anti-aging foods, respectively. Likewise, it was ascertained When asked whether subjects intend to purchase anti-aging convenient food if it was is developed. The 67.3 percent and the 72.7 percent indicated their intentionded to purchase the normal product and constitutional products, respectively. Resultantly, anti-aging convenient food was in demand to some extent. Given that anti-aging products are in high demand, In such a case, senile severity (p<0.05), anti-aging possibility in constitutional foods (p<0.001) and anti-aging action (p<0.001) are regarded as variables in the purchase of the normal products. In the case of relation to constitutional products, anti-aging possibility in constitutional food (p<0.001) and anti-aging action (p<0.001) were regarded as variables.

• 한국가정과교육학회지
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• 제23권4호
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• pp.105-124
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• 2011

본 연구는 고령화사회에 대비하기 위하여 인문계와 가사 실업 전문계 고등학생을 대상으로 기술 가정, 가정과학, 인간발달 수업 시간에 자신의 노후를 성공적으로 준비하기 위한 실천적 문제 중심 수업과 강의식 수업을 적용하고, 그 효과를 알아보는데 목적이 있다. 이를 위해 인문계 고등학교와 가사 실업 전문계 고등학교의 정규 교과목 수업 시간에 실험집단은 실천적 문제 중심으로 총 5차시의 수업을 실시하고, 비교집단에는 강의식으로 총 5차시의 수업을 실시하였다. 그리고 실험집단과 비교집단의 사전-사후검사를 분석하여 교수법의 차이, 학교계열의 차이를 알아보았으며, 교수법과 학교계열에 따라 노인에 대한 이해 변인과 노후생활 준비 변인에 차이가 있는지를 알아보았다. 이러한 연구 목적을 달성하기 위해 인문계 고등학교 4개교, 가사 실업 전문계 고등학교 2개교를 임의표집 하여 총 41학급, 1,263명을 대상으로 하였으며, 2009년 10월부터~2010년 11월까지 총 9명의 교사가 실험집단과 비교집단에 각각 수업을 실시하였다. 자료분석과 통계처리는 SPSS 12.0프로그램을 이용하여 평균과 표준편차, t-검증, 공분산분석을 실시하였다. 인문계와 가사 실업 전문계 고등학생을 대상으로 노후 준비를 위한 가정과 수업을 적용한 결과, 가사 실업 전문계 보다는 인문계에서, 강의식 수업보다는 실천적 문제 중심 수업이 고등학생들의 노인에 대한 이미지, 노인에 대한 지식, 자녀로부터의 부양의식, 노후생활준비도, 노인복지서비스 필요도를 향상시키는데 더 효과가 있는 것으로 나타났다. 이에 따라 실천적 문제 중심 노후 준비 교육의 후속연구로서, 고등학생의 노후준비교육을 일반화 할 수 있도록 보다 많은 학교에서 기술 가정, 가정과학, 인간발달의 정규 교과목 수업에 적용하고 그 효과를 검증하는 연구가 실시되기를 바라며, 고령화 사회에 대한 교육적 대응으로 노후생활 준비교육은 새로운 교육과정에서도 지속적으로 반영되어야 할 것을 제언하였다.

• 한국콘텐츠학회논문지
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• 제16권9호
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• pp.460-472
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• 2016

본 연구는 베이비붐 세대의 인구 통계학적 특성에 따른 성공적 노화 인식과 노후 준비 정도를 살펴보고, 더 나아가 성공적 노화 인식이 노후 준비에 미치는 영향력을 파악하는데 그 목적을 두고 있다. 전국에서 814명의 베이비붐 세대를 대상으로 2015년 5월 1일부터 9월 15일까지 설문지 조사가 실시되었으며, SPSS WIN18.0을 이용하여 자료를 분석한 결과는 다음과 같다. 첫째, 베이비붐 세대의 성공적 노화 인식은 학력, 주관적 경제수준, 주관적 건강상태, 배우자 유무에 따라 유의한 차이가 나타났다. 둘째, 베이비붐 세대의 노후 준비 정도는 학력, 직업, 주관적 경제수준, 주관적 건강상태에 따라서 유의한 차이가 나타났다. 셋째, 성공적 노화 인식이 높을수록 노후를 위한 준비에 보다 적극적인 것으로 나타났다. 따라서 베이비붐 세대들의 성공적 노화와 노후 준비에 관한 정책과 서비스는 인구 통계학적 특성을 고려한 개별화된 방안이 마련되어야 하며, 동시에 성공적 노화에 관한 이론적 교육 및 노후 준비에 관한 실천적 프로그램이 함께 병행되어질 필요가 있다.

• 한국보건교육건강증진학회:학술대회논문집
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• 한국보건교육건강증진학회 1999년도 3rd International Symposium
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• pp.117-128
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• 1999

오늘날 일본의 건강상황을 건강지표 등으로 평가하면 상당히 개선되어, 평균수명은 남성이 77.19세, 여성이 83.32세로 장수국가가 되었다. 65세 이상이 인구의 15.7%(1997)를 차지하는 고령화 사회에서 앞으로는 단지 질병이나 장애를 방지하고 장수하는 것만이 아니라, 더욱 충실한 인생을 보낼 수 있는 quality of life를 염두에 두지 않으면 안 된다. 따라서, 여기서는 생활의 질을 높이기 위해서 일본에서 행하여지고 있는 지역의 건강증진 사업을 중심으로 검토하려고 한다.

• 청정기술
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• 제29권1호
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• pp.39-45
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• 2023

To investigate the effects of Mg addition at different aging times and temperatures, Cu/MgO/Al₂O₃ catalysts were synthesized for the low-temperature water gas shift (LT-WGS) reaction. The co-precipitation method was employed to prepare the catalysts with a fixed Cu amount of 30 mol% and varied amounts of Mg/Al. Synthesized catalysts were characterized using XRD, BET, and H₂-TPR analysis. Among the prepared catalysts, the highest CO conversion was achieved by the Cu/MgO/Al₂O₃ catalyst (30/40/30 mol%) with a 60 ℃ aging temperature and a 24 h aging time under a CO₂-rich feed gas. Due to it having the lowest reduction temperature and a good dispersion of CuO, the catalyst exhibited around 65% CO conversion with a gas hourly space velocity (GHSV) of 14,089 h-1 at 300 ℃. However, it has been noted that aging temperatures greater or less than 60 ℃ and aging times longer than 24 h had an adverse impact, resulting in a lower surface area and a higher reduction temperature bulk-CuO phase, leading to lower catalytic activity. The main findings of this study confirmed that one of the main factors determining catalytic activity is the ease of reducibility in the absence of bulk-like CuO species. Finally, the long-term test revealed that the catalytic activity and stability remained constant under a high concentration of CO₂ in the feed gas for 19 h with an average CO conversion of 61.83%.

• 대한간호학회지
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• 제17권1호
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• pp.64-78
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• 1987

This study is attempt to submit a basic material to help the efficient nursing management which supports and to understand the alienation which they percieve social-psychologically and physical aging bringing about the phf·sical powerlessness, to understand the old people in hospitals and in community and should build up their health. The data collection of the study which has been done on Sept. 7 to Sept. 20, 1986 is objected to 300 people of 65 years old of age or more of male and female who are staying at home. Analysis of the Data was done by use of percentage, t-test, ANOVA and Pearson Correlation Coefficients. The results of study are summerized as follows: 1. According to each age group of old people(p= .0008), family living together concreteness (p=.0000), the level of education (p=.0020), how much they are participating in leisure activity (p=.0001), whether they have mate or not (p=.0000), whether they have religion or not (p=.0000), the level of alienation showed difference statistically. Also, according to sex (p=.4315), whether they have income or not (p=.1197), the level of alienation did not show any difference statistically. 2. According to each age group of old people (p=.0000), family living together concreteness (p=.0060), the level of education (p=.0000), sex (p=.0000), whether they have mate or not (p=.0000), whether they have religion or not (p=.0067), whether they have income or not (p=.0000), the level of physical aging showed difference statistically. Also, according to how much they are participating in leisure activity, the level of physical aging did not show any difference statistically (p=4879). 3. The level of alienation and physical aging in old people had positive correlation (r=.5436, p<.001). From the above result, the level of social, psychological alienation and physical aging showed high for the old who had no mate, no religion, low in their educational level, living separately' with the family and for those who do not participate much in the leisure activities, The old people who feel the social, psychological alienation can expedite the physical aging and physical aging can be result from social psychological loneliness and alienation. Therefore, for the successful aging of the old people in the community with these weak points, we should provide them with physical and emotional, psycho-logical support and care in the basis of understanding in socialization process and the character of the physical functional change.

• 한국콘텐츠학회논문지
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• 제13권10호
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• pp.365-374
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• 2013

본 연구는 노후에 대한 인식이 국가 민간의료기관 근로자간에 따라 차이가 있는지, 또한 노후인식이 노후준비에 어떠한 영향을 미치는지를 분석하고자 하였다. 연구대상은 부산의 보건소와 병 의원의 근로자 783명을 대상으로 진행하였다. 자료 분석은 SPSS 21.0 프로그램을 이용하여 빈도분석, t-test, 위계적 회귀분석을 실시하였다. 본 연구의 결과는 다음과 같이 나타났다. 첫째, 국가 민간의료기관의 근로자간에 노후에 대한 인식, 정부정책에 대한 만족도, 노후준비에 대해서 부분적으로 차이가 있었으며, 국가 근로자가 민간 근로자 보다 더 잘 인지하고, 만족하며, 비교적 준비하고 있었다. 또한 노후에 대한 인식과 정부정책 만족도는 모두 보통 수준 이상으로 나타났지만, 노후 준비는 미흡한 것으로 나타났다. 둘째, 노후 준비에 영향을 미치는 요인을 알아본 결과 국가의료기관과 민간의료기관 근로자에서 각각 다르게 나타났다. 또한 노후 준비에 미치는 영향은 부분적으로 차이를 보였다. 결론적으로 국가 민간의료기관 근로자간 노후준비에 미치는 영향에는 차이가 있었다. 본 연구는 노후준비에 대한 교육 및 정책수립을 위한 기초자료로 제공하려한다.

• 비파괴검사학회지
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• 제29권6호
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• pp.591-602
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• 2009

The Compton backscatter technique has been applied to lap-joint in aircraft structure in order to determine mass loss due to exfoliative corrosion of the aluminum alloy sheet skin. The mass loss of each layer has been estimated from Compton backscatter A-scan including the aluminum sheet, the corrosion layer, and the sealant. A Compton backscattering imaging system has been also developed to obtain a cross-sectional profile of corroded lap-splices of aging aircraft using a specially designed slit-type camera. The camera is to focus on a small scattering volume inside the material from which the backscattered photons are collected by a collimated scintillator detector for interpretation of material characteristics. The cross section of the layered structure is scanned by moving the scattering volume through the thickness direction of the specimen. The theoretical model of the Compton scattering based on Boltzmann transport theory is presented for quantitative characterization of exfoliative corrosion through deconvolution procedure using a nonlinear least-square error minimization method. It produces practical information such as location and width of planar corrosion in layered structures of aircraft, which generally cannot be detected by conventional NDE techniques such as the ultrasonic method.

• 대한예방한의학회지
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• 제27권2호
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• pp.1-22
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• 2023

Objectives : The aim of this study was to introduce the development process of Korean medicine health aging program for the older that is suitable for applied at public health center. Methods : For the development of the draft of health promotion program, we conducted a literature review of previous studies through searching international and domestic databases. The opinions of several experts were also colleted. Results : The details of 8-week of Korean medicine healthy aging program are as follows: 8-week of taking herbal medicines (Yukmijihwang-tang or Palmijihwang-tang, or Jaeumganghwa-tang) based on counseling with Korean medicine doctor, qigong, acupuncture on head, abdominal hotpack, taking nuts, and health education Conclusions : This healthy aging program can help to develop the healthy lifestyle habits and increase the general health status of community seniors.