• Title/Summary/Keyword: edma

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Preparation and Separation Properties of Polymer Gel for Chromatography (크로마토그래피용 고분자 겔의 제조 및 분리특성)

  • Kim, Kong-Soo;Kang, Seog-Ho;Park, Myung-Hwan;Lee, Sang-Ho
    • Applied Chemistry for Engineering
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    • v.5 no.6
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    • pp.1009-1015
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    • 1994
  • Monodisperse porous poly(styrene-co-divinylbenzene)(St-DVB) gel and poly(acrylonitrile-co-ethylene dimethacrylate)(AN-EDMA) gel have been prepared by seed polymerization using polystyrene seeds, which were prepared by dispersion polymerization. The St-DVB and AN-EDMA gels had a narrow size distribution and pores suitable for packing materials of HPLC. The columns packed with these gels were proved to have high efficiency for GPC or HPLC coluuns. Adsorption properties of $Cu^{2+}$, $Cd^{2+}$ and ${UO_2}^{2+}$ ions on AAN-EDMA gel prepared from amidoximation of AN-EDMA gel were also determined.

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Capture of Metal Ions by Cross-linked Sulfonic Acid Type Ion Exchange Membranes (가교제를 도입시킨 술폰산형 이온교환막의 금속이온 포집)

  • Kim, Min;Kim, Ye-Jin;Park, Sang-Jin
    • Membrane Journal
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    • v.19 no.4
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    • pp.333-340
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    • 2009
  • This paper is designed with the purpose of improving the efficiency of the sulfonic acid ion exchange membranes by radiation induced graft polymerization. It has been shown that the porous hollow fiber membranes could cause permeability blocking between pores and ion exchanged graft chains. Addition of crosslinker such as N-ethylene glycol dimethacrylate will permit to increase the permeation flux. In this research, the ethylene glycol dimethacrylate (EDMA) and diethylene glycol dimethacrylate (DDMA) with different length are used as crosslinkers. The ion exchanged cross-linked membrane (EDMA, DDMA) containing sulfonic acid group by radiation induced grafted polymerization are sn died for adsorb metal ions (Pb). It has been shown that adsorbed metal ions ($Pb^{2+}$) for the EDMA and DDMA membranes with the density of sulfonic acid groups, 1.40 mmol/g and 2.14 mmol/g, respectively are 13.82 mg/g, 17.37 mg/g, accordingly.

Graft copolymerization of GMA and EDMA on PVDF to hydrophilic surface modification by electron beam irradiation

  • Lim, Seung Joo;Shin, In Hwan
    • Nuclear Engineering and Technology
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    • v.52 no.2
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    • pp.373-380
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    • 2020
  • This study was carried out to convert the hydrophobic characteristics of PVDF to hydrophilic. Poly(-vinylidene fluorine) (PVDF) was grafted by electron beam irradiation and sulfonated. The grafting degree of modified PVDF increased with the monomer concentration, but not the conversion degree. From the results of FTIR and XPS, it was shown that the amount of converted sulfur increased with the grafting degree. The radiation-induced graft polymerization led to decrease fluorine from 35.7% to 21.3%. Meanwhile, the oxygen and sulfur content increased up to 8.1% and 3.2%. The pore size of modified membranes was shrunken and the roughness sharply decreased after irradiation. The ion exchange capacity and contact angle were investigated to show the characteristics of PVDF. The enhanced ion exchange capacity and lower contact angle of modified PVDF showed that the hydrophilicity played a role in determining membrane fouling. Electron beam irradiation successfully modified the hydrophobic characteristics of PVDF to hydrophilic.

A Clinic Study on Soyangin Lower Limb Edema Caused by Deep Vein Thrombosis (심부정맥혈전증으로 인한 소양인(少陽人) 하지부종(下肢浮腫) 치험 1례)

  • Kim, Hyun-Ho;Hong, Sor-I;Lim, Eun-Chul;Kim, Tae-Hwan
    • Journal of Sasang Constitutional Medicine
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    • v.18 no.3
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    • pp.202-209
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    • 2006
  • 1. Objectives The purpose of this study is to evaluate the effects of Sasang Constitutional medical diagnosis and treatment on Soyangin Edema caused by Deep Vein Thrombosis. 2. Methods The Subject is a 75 years old woman who has a left lower limb edema caused by Deep Vein Thrombosis, we had diagnosed her as Soyangin and prescribed Sasang Constitutional Medicine. We evaluated with length of patient's calf, thigh, ankle circumference and pitting edema, skin flare after medication. 3. Results Lower limb edma of a Soyangin patient responded well to the treatment with Dojeokganggi-tang(導赤降氣湯). 4. Conclusions This case study shows an efficient result by using Dojeokganggi-tang in treatment of Soyangin edema patient.

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Chromatographic Characterization of Pentoxifylline and a Mixture of Caffeine-theophylline Imprinted Polymer (Pentoxifylline과 Caffeine-theophylline Imprinted Polymers의 크로마토그래피 특성)

  • 홍승표;왕덕선;구윤모;노경호
    • KSBB Journal
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    • v.18 no.1
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    • pp.65-69
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    • 2003
  • Two molecular imprinted polymers (MIPs) were prepared by using pentoxifylline and a mixture of caffeine-theophylline (2:1, mole ratio) as the templates, MAA as the monomer, and EDMA as the crosslinker The obtained polymer particles (particle size 25-35 $\mu\textrm{m}$) were packed into a HPLC column (150$\times$3.9mm). The selectivity and chromatographic characterization of the imprinted polymers were studied using pentoxifylline, caffeine, theophylline, theobromine as samples and acetonitrile as the mobile phase, Both imprinted polymers showed increased affinity for structural analogues. By using a mixture of caffeine-theophylline templates MIPs, good separations of caffeine, theobromine and theophylline were obtained, and pentoxifylline and caffeine were partly separated.

Polymer Catalysts by Molecular Imprinting: A Labile Covalent Bonding Approach

  • Kim, Jong Man;An, Gwang Deok;Alexander G. Strikovsky;Guenter Wulff
    • Bulletin of the Korean Chemical Society
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    • v.22 no.7
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    • pp.689-692
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    • 2001
  • An imprinting technique with labile covalent interactions has been developed in the design of new polymer catalysts. The template monomer 2 was prepared and copolymerized with DVB or EDMA to provide the polymer with a cavity having the shape of th e transition state of the reaction as well as binding sites for the substrate and catalytic functionalities. The rate of hydrolysis of diphenyl carbonate (1) in the presence of the imprinted polymer IP-DVB-THF was found to be 120 times faster than the background uncatalyzed reaction. A Km of 32 mM and a kcat of 1.8 ${\times}$ 10-3min-1 were observed from Michaelis-Menten kinetics with the imprinted polymer IP-DVB-THF.

Topical Anti-inflammatory Activity of Dianemycin Isolated from Streptomyces sp. MT 2705-4

  • Lee, Song-Jin;Kim, Hyun-Pyo;Park, Byung-Keun;Ahn, Soon-Cheol;Lee, Hyun-Sun;Ahn, Jong-Seog
    • Archives of Pharmacal Research
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    • v.20 no.4
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    • pp.372-374
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    • 1997
  • In order to develop new anti-inflammatory agents having different action mechanisms compared with nonsteroidal and steroidal anti-inflammatory drugs, the culture broths of various actinomycetes isolated from soil were screened using an in vivo mouse ear edma assay and one strain (Streptomyces sp. MT 2705-4: KCTC 8651 P) was selected. Activity-guided purification led to the isolation of a polyether compound, dianemycin. Topically, dianemycin showed a potent anti-inflammatory activity in mouse ear edema induced by croton-oil or arachidonic acid.$ED_{50}$value of dianemycin was found to be 0.8 mg,/ear compared to 0.4 mg/ear of prednisolone in croton-oil ear edema. However, dianemycin did not show the inhibitory activity in UV-erythema and delayed hypersensitivity reaction. These results indicate that dianemycin is a potential topical anti-inflammatory agent.

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DSP Optimization for Rain Detection and Removal Algorithm (비 검출 및 제거 알고리즘의 DSP 최적화)

  • Choi, Dong Yoon;Seo, Seung Ji;Song, Byung Cheol
    • Journal of the Institute of Electronics and Information Engineers
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    • v.52 no.9
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    • pp.96-105
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    • 2015
  • This paper proposes a DSP optimization solution of rain detection and removal algorithm. We propose rain detection and removal algorithms considering camera motion, and also presents optimization results in algorithm level and DSP level. At algorithm level, this paper utilizes a block level binary pattern analysis, and reduces the operation time by using the fast motion estimation algorithm. Also, the algorithm is optimized at DSP level through inter memory optimization, EDMA, and software pipelining for real-time operation. Experiment results show that the proposed algorithm is superior to the other algorithms in terms of visual quality as well as processing speed.

Antioxidative Activity and Therapeutic Effect of the Hydrogel Preparations of Scutellariae Radix and Zingiberis Rhizoma on Dermatitis (황금 및 생강 복합 수용성겔 제제의 항산화 활성 및 피부염 치료효과)

  • Yang, Jae-Heon;Kim, Dae-Keun;Yun, Mi-Young;Ahn, Jae-Kyu
    • Journal of Pharmaceutical Investigation
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    • v.36 no.4
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    • pp.253-262
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    • 2006
  • This study was performed to investigate the effects of treatment for dermatitis using the herbal gel preparations. Scutellariae Radix(SR) and Zingiberis Rhizoma(ZR) were used for the purpose of herbal preparations. Baicalin, baicalein are the ingredients of SR, having biological effects like anti-inflammatory, anti-oxidative, anti-bacterial and antiallergic action. 6-Gingerol is one of the ingredients of ZR having biologicai effects like anti-inflammatory and analgesic action. The three types of hydrogels(SRE, SRH, SZH) were formulated with Carbopol 940, Labrasol, Triethanolamine etc. Baicalin was hydrolysed to baicalein by $\beta$-glucuronidase for the purpose to increase rate of skin permeation. Content of ingredients by HPLC determination, rate of skin permeation using Franz type diffusion cell, anti-oxidative activity for the free radical, hydroxyl radical, superoxide, anti-inflammatory by using carrageenan injection, efficacy on the dermatitis induced by 2,4-dinitro-chlorobenzene(DNCB) were experimented. Baicalein showed higher permeability than baicalin, so it is considered that baicalein was more suitable form than baicalin for transdermal absorption by its lipophilic property. In the anti-oxidative experiments, SZH gel was the most effective scavenging activity than the other gels in all experiments. In anti-inflammatory test, SRM and SZH gel more decreased edma rapidly than SRE gel. In case of using SZH gel, treatment period for the dermatitis was more declined than that of other gel groups. These results suggests that the SZH hydrogel could be suitable preparations for the treatment of dermatitis.

Case about cardiogenic general edema of Soeumin apoplexy patient (소음인(少陰人) 전신부종(全身浮腫)에 대한 증례(證例))

  • Shin, Mi-ran;Kim, Sun-hyung;Kim, Dal-rae
    • Journal of Sasang Constitutional Medicine
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    • v.12 no.1
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    • pp.265-270
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    • 2000
  • Occasionally, apoplexy is caused by functional or physiologic cardiopulmonary abnormality. In addition, theses may become the factor of aggravating apoplexy and involve complication. If patient has cardiopulmonary disease, progressing of apoplexy is commonly used to be accelerate and prognosis is deteriorative. There by the patient who has cardiopulmonary disease, should be particularly treated for cardiopulmonary disease. We got good result, during treat Soeumin cerebral vascular infarction patient who has pulmonary edema leaded from congestive heart failure, with Sasang Constitutional treatment. Therefore I reported them here. She was 68 years old, female patient. She visited our hospital for apoplexy with right side hemiparesis, dysphagia, dysphasia. After her admission into our hospital, we knew that she has congestive heart failure. The diagnosis is established. She presented with severe general edema and pulmonary edema. Although Soeumin edema usually classified as Taiyin Disease, we classified this as Shaoyin Disease, through diet, discharge, sleep, tongue and symptoms. We has prescribed Gungguichongsoyijung-tang(芎歸蔥蘇理中湯) in accordance with the principle of invigorating the Spleen and lower Yin(建碑而降陰). And her symptoms has improved.

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