• Title/Summary/Keyword: early event

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A Study on the Development of the Water-Bulwark System for Early Suppression in the Event of Fire in Highway Tunnel (고속도로 터널 내 화재발생 시 초기 진압용 화재진압시스템(Water-Bulwark System) 개발 연구)

  • Chung-Hyun, Baek
    • Journal of the Korea Safety Management & Science
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    • v.24 no.4
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    • pp.95-100
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    • 2022
  • In general, fire accidents in tunnels are sufficiently preventable, but the damage is very large. Therefore, the number of highway traffic accidents is high in spring when spring fatigue occurs and the traffic volume for maple travel increases. In particular, when analyzing the cause of death of people killed in fire accidents in tunnels, it is analyzed that most of them are suffocated by smoke. Therefore, in this study, it can be said that it is meaningful to make a social contribution to reduce the number of traffic accident deaths by establishing an efficient fire suppression system for fire accidents in tunnels.

Adrenal insufficiency development during chemotherapy plus anti-programmed death receptor-1 monoclonal antibody (tislelizumab) therapy in patients with advanced gastric cancer: two case reports

  • Baek, Jin Ho
    • Journal of Yeungnam Medical Science
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    • v.39 no.1
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    • pp.62-66
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    • 2022
  • Immune checkpoint inhibitor (ICI)-associated adrenal insufficiency is rare but may become a serious adverse event in patients treated with ICIs. The present case report documents two cases of adrenal insufficiency developed during chemotherapy plus tislelizumab (百泽安, Baize'an; BeiGene Ltd.) therapy in patients with advanced gastric cancer. Adrenal insufficiency developed after 6 and 13 cycles of treatment and was well controlled with hydrocortisone. The patients also developed hypothyroidism, which was managed with levothyroxine. Two patients showed a partial response, and one patient out of two achieved a near-complete response, sustaining over 11 months. Increased awareness of ICI-related adrenal insufficiency is crucial for early detection and prompt management of patients treated with ICIs.

Study on Runoff Characteristics of Non-point Source in Rural Area of Seomjin Watershed (섬진강 유역 농촌지역의 비점오염원 배출특성에 관한 연구)

  • Park Sung-Chun;Oh Chang-Ryol;Jin Young-Hoon;Kim Dong-Soo
    • Journal of Environmental Science International
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    • v.14 no.11
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    • pp.1057-1062
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    • 2005
  • The present study investigated runoff characteristics of non-point pollutants and discharge load amount according to the land utilization in Yeinam river basin. The land utilization of target basin was divided into paddy field, dry field, forest, residential area and composition area. The study on the runoff characteristics of non-point pollutants by rainfall-runoff process showed that COD, SS and T-P had the first-flushing effect with relatively high concentration in early-stage of the rainfall-runoff process, but the T-P revealed similar runoff characteristics. Event Mean Concentration(EMC) of BOD and COD according to the land utilization revealed the range of $3.11\~15.50mg/L$ and $3.37\~33.42mg/L$, and the highest concentration of EMC corresponding to BOD and COD was detected in the paddy field. The EMC of SS showed $1.7\~305.02mg/L$ and it's highest concentration was found in the dry field. The EMC of T-N and T-P represented the highest concentration in the paddy field and dry field with range of $0.91\~8.76mg/L$ and $0.02\~0.44mg/L$.

Drought Triggers and Monitoring System (가뭄 경보기준과 모니터링 시스템)

  • Lee, Dong-Ryul;Lee, Dea-Hee;Kang, Shin-Uk
    • Journal of Korea Water Resources Association
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    • v.36 no.3 s.134
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    • pp.375-384
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    • 2003
  • Severe drought tends to occur in almost event five years in Korea. Drought responses have been well operated in close collaboration with the central, local government and the water management authorities on the institutional framework. However, the responses are usually post-activities to a drought event. The responses often face difficulties in operating and managing process due to an absence of a drought monitoring system and drought triggers. The objective of this study is to set up drought triggers through a time-spatial interpretation of drought index and the government responses during historical drought events. Drought triggers are divided into four categories: advisory, watch, warning and emergency stage. The range and drought-impacted area of an each stage in triggers have been addressed using drought index. Furthermore, a web-based drought monitoring system is illustrated.

Pituitary Apoplexy : Surgical Experience with 16 Patients

  • Lee, Jae-Hyun;Kim, Jae-Hyoo;Moon, Kyung-Sub;Joo, Sung-Pil;Lee, Jung-Kil;Kim, Soo-Han
    • Journal of Korean Neurosurgical Society
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    • v.42 no.2
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    • pp.83-88
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    • 2007
  • Objective : Pituitary apoplexy, resulting from an acute infarction or hemorrhage mainly in pituitary adenomas, is a rare yet major clinical event with neurological, ophthalmological and hormonal emergent consequences. The authors review our surgical experience with a series of 16 cases of pituitary apoplexy. Methods : The cases of pituitary apoplexy, operated via trans-sphenoidal approach in our hospital between 1998-2005, were retrospectively analyzed in terms of their clinicoradiological features, pathological findings and surgical outcomes. Results : The mean age of patients (9 male and 7 female) was 47.1 years. The average time of presentation after onset of symptom was 8.9 days. Pituitary apoplexy occurred as an initial manifestation of pituitary adenoma in all patients. Headache was the most common presenting symptom (94%). Visual disturbance was found in 56% of patients. Thirty-one percent of the patients had hypopituitarism. On magnetic resonance imaging, this entire catastrophic event accompanied with macroadenoma in a mean size of 22.5 mm. Only four patients needed postoperative hormone replacement therapy. Three of them showed preoperative hypopituitary function, and one patient in normal pituitary function. There was no specific complication in any of these patients. Conclusion : Early trans-sphenoidal decompression with high-dose corticosteroid replacement showed good outcomes of pituitary apoplexy.

Molecular evolution of cpDNA trnL-F region in Korean Thalictrum L. (Ranunculaceae) and its phylogenetic relationships: Impacts of indel events (한국산 꿩의다리속(미나리아재비과)의 cpDNA trnL-F 지역의 분자진화와 유연관계: Indel events의 영향)

  • Park, Seongjun;Kim, Hyuk-Jin;Park, SeonJoo
    • Korean Journal of Plant Taxonomy
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    • v.42 no.1
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    • pp.13-23
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    • 2012
  • The trnL-F region islocated in the large single-copy region of the chloroplast genome. It consists of the trnL gene, the trnL intron, and the trnL-F IGS. Molecular evolution and phylogenetic relationships in Korean Thalictrum L. were investigated using data from the cpDNA trnL-F region. Bayesian and parsimony analyses of the data set with the gap characteristics recovered well-resolved trees that are topologically similar, with clades supported by some indels evolution. Indel events of cpDNA trnL-F in Korean Thalictrum were interpreted as phylogenetically informative characteristics. Sect. Physocarpum (excluding T. osmorhizoides) was an early-diverging group with in the genus and the remaining section formed strongly supported clades. Korean Thalictrum has various evolutionary patterns, such as the spatial distribution of the nucleotide diversity and transversion-type base substitutions in the trnL-F region.

E-Business and Simulation

  • Park, Sung-Joo
    • Proceedings of the Korea Society for Simulation Conference
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    • 2001.10a
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    • pp.9-10
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    • 2001
  • Simulation has been evolved with the advance of computer and technique of modeling application systems. Early simulations were numerical analysis of engineering models known as continuous simulation, analysis of random events using various random number generators thus named as Monte Carlo simulation, iud analysis o(\\\\`queues which are prevalent in many real world systems including manufacturing, transportation, telecommunication. Discrete-event simulation has been used far modeling and analyzing the systems with waiting lines and inefficient delays. These simulations, either discrete-event, continuous, or hybrid, have played a key role in industrial age by helping to design and implement the efficient real world systems. In the information age which has been brought up by the advent of Internet, e-business has emerged. E-business, any business using Internet, can be characterized by the network of extended enterprises---extended supply and demand chains. The extension of value chains spans far reaching scope in business functions and space globally. It also extends to the individual customer, customer preferences and behaviors, to find the best service and product fit for each individual---mass customization. Simulation should also play a key role in analyzing and evaluating the various phenomena of e-business where the phenomena can be characterized by dynamics, uncertainty, and complexity. In this tutorial, applications of simulation to e-business phenomena will be explained and illustrated. Examples are the dynamics of new economy, analysis of e-business processes, virtual manufacturing system, digital divide phenomena, etc. Partly influenced by e-business, a new trend of simulation has emerged called agent-based simulation, Agent-based simulation is a technique of simulation using software agent that have autonomy and proactivity which are useful in analyzing and integrating numerous individual customer's behavior. One particular form of agent-based simulation is swarm. This tutorial concludes with the illustration of swarm or swarm Intelligence applied to various e-business applications, and future directions and implications of this new trend of simulation.

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Developing Automatic Lens Module Assembly System Using 3D Simulation (3D 시뮬레이션을 활용한 렌즈모듈 자동화조립시스템 개발)

  • Moon, Dug-Hee;Lee, Jun-Seok;Baek, Seung-Geun;Zhang, Bing-Lin;Kim, Yeong-Gyoo
    • Journal of the Korea Society for Simulation
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    • v.16 no.2
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    • pp.65-74
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    • 2007
  • Virtual manufacturing (VM) is a powerful technology for developing a new product, new equipment and new manufacturing system, and three-dimensional (3D) simulation is a core technology in VM. 3D simulation involves both mechanical simulation and discrete event simulation. This paper introduces a case study of implementing 3D simulation for developing an automatic assembly line in a Korean optical factory. This factory produces a lens module that is the part of a phone-camera. 3D simulation technology is applied from the early stage of development. In the conceptual design and the initial design phases for individual equipment, 3D mechanical simulation using $CATIA^{(R)}$ and $IGRIP^{(R)}$ is conducted. 3D discrete event simulation with $QUEST^{(R)}$ is applied to the detailed design of the equipment and of the whole system. The focus of the simulation is to verify the technical and economical feasibility of the new automatic system. As a result, the takt time is reduced to the quarter of the manual system, and the number of workers in a line is reduced tremendously.

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Source term estimation using least squares method in a radiological emergency (원자력 비상시 최소자승법을 이용한 선원항의 추정)

  • Jeong, Hyo-Joon;Kim, Eun-Han;Suh, Kyung-Suk;Hwang, Won-Tae;Han, Moon-Hee
    • Journal of Radiation Protection and Research
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    • v.29 no.3
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    • pp.157-163
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    • 2004
  • Atmospheric dispersion modelling has been widely used to predict the fate and transport of radioactive or toxic materials released from nuclear facilities which is an unlikely accidental event. To improve the forecasting performance of the dispersion model, it is required that source rate and dispersion characteristics must be defined appropriately. Generally, source term of the radioactive materials is much uncertain at the early phase of an accidental event. In this study, we computed the source rate with the experimental field data monitored at the Yeoung-Kwang nuclear site and obtained the optimal source rate to minimize the errors between the measured concentrations and the computed ones by the Gaussian plume model. Computed source term showed a good result within 24% of the artificially released source rate.

KMT-2016-BLG-0212: FIRST KMTNET-ONLY DISCOVERY OF A SUBSTELLAR COMPANION

  • Hwang, K.H.;Kim, H.W.;Kim, D.J.;Gould, A.;Albrow, M.D.;Chung, S.J.;Han, C.;Jung, Y.K.;Ryu, Y.H.;Shin, I.G.;Shvartzvald, Y.;Yee, J.C.;Zang, W.;Zhu, W.;Cha, S.M.;Kim, S.L.;Lee, C.U.;Lee, D.J.;Lee, Y.;Park, B.G.;Pogge, R.W.
    • Journal of The Korean Astronomical Society
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    • v.51 no.6
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    • pp.197-206
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    • 2018
  • We present the analysis of KMT-2016-BLG-0212, a low flux-variation ($I_{flux-var}{\sim}20mag$) microlensing event, which is in a high-cadence (${\Gamma}=4hr^{-1}$) field of the three-telescope Korea Microlensing Telescope Network (KMTNet) survey. The event shows a short anomaly that is incompletely covered due to the brief visibility intervals that characterize the early microlensing season when the anomaly occurred. We show that the data are consistent with two classes of solutions, characterized respectively by low-mass brown-dwarf (q = 0.037) and sub-Neptune (q < $10^{-4}$) companions. Future high-resolution imaging should easily distinguish between these solutions.