• Journal of Korea Society of Digital Industry and Information Management
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• v.6 no.2
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• pp.29-38
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• 2010

It often occur to nature disaster that like earthquake, typhoon, etc. around KOREA. A Haiti and Chile also metropolitan area of KOREA occur earthquake. in result, People think of nature disaster. Structures of present age are easily affected by nature disaster. So we are important that warn of dangerous situation as soon as possible. On this study, I introduce Integrated monitoring system that administrator check a event as early. I develop Monitoring System using SMS(Short Message Service). Administrator always monitor structure on real-time using mobile web-page. As Administrator using mobile device like PDA, Administrator always monitor structure. As using this system, Damage of nature disaster is minimized and is prevented post damage.

• Atmosphere
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• v.11 no.2
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• pp.6-12
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• 2001

The East Asian monsoon is generally accompanied with the quasi-stationary front along the northern and northwestern periphery of the subtropical anticyclone in the boundary zone of the polar cold air mass and the tropical warm air mass. The rainy season in Korea has been called as Changma since the middle of 1500s. In meteorology, the rainy season with the quasi-stationary front, the Changma front, during the early summer has been defined as the Changma since 1905. The difference of meaning on Changma between meteorologists and the general public sometime does give a confusion. For example, the heavy rainfall event after the retreat of Changma is recognized as Changma by the general public, but not by most of meteorologists. The decision of the onset and retreat dates of Changma among the meteorologists is also ambiguous because of different viewpoints on the definition of Changma. In this study we survey the etymology and definition of Changma.

• Archives of Craniofacial Surgery
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• v.15 no.3
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• pp.121-124
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• 2014

The use of the implantable Doppler device eases the burden of free flap monitoring, and allows caregivers to notify healthcare personnel of a potential vascular event. A 24-year-old female patient underwent anterolateral thigh adipofascial flap surgery to provide a buried flap on the left temporal area for a depressed and infected skull wound. The author was able to salvage the flap from two venous occlusions, which was made possible by early notifications from the caregiver who reported changes in the Doppler signal.

• Bulletin of the Korean Chemical Society
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• v.30 no.7
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• pp.1567-1572
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• 2009

Conformational change of ubiquitin variant with valine to alanine mutation at sequence position 26 was studied by varying solvent pH. Fluorescence emission spectra indicated that this variant ubiquitin has some residual structures in acidic and basic solution as compared to denaturant-induced unfolded state. Far-UV circular dichroic spectra indicated that the base-denatured state had more secondary structure than the acid-denatured state. Near-UV circular dichroic spectra indicated that the aromatic side-chains were in the relatively more rigid environment in the base-denatured state than those in the acid-denatured state. Although it appears that the more tertiary structure present in the base-denatured state, refolding reactions measured by stopped-flow fluorescence device suggest that both the acid- and base-denatured states occur before the major folding transition state. The acid- and base-denatured states are considered to reflect the early event of protein folding process.

• Journal of Korean Society of Industrial and Systems Engineering
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• v.31 no.4
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• pp.49-58
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• 2008

This paper proposes a methodology to measure the risk level in real-time for Business Activity Monitoring (BAM). A decision-tree methodology was employed to analyze the effect of process attributes on the result of the process execution. In the course of process execution, the level of risk is monitored in real-time, and an early warning can be issued depending on the change of the risk level. An algorithm for estimating the risk of ongoing processes in real-time was formulated. Comparison experiments were conducted to demonstrate the effectiveness of our method. The proposed method detects the risks of business processes more precisely and even earlier than existing approaches.

• Molecules and Cells
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• v.27 no.2
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• pp.211-215
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• 2009

Toll-like receptors (TLRs) play a critical role in sensing microbial components and inducing innate immune and inflammatory responses by recognizing invading microbial pathogens. Lipopolysaccharide-induced dimerization of TLR4 is required for the activation of downstream signaling pathways including nuclear factor-kappa B ($NF-{\kappa}B$). Therefore, TLR4 dimerization may be an early regulatory event in activating ligand-induced signaling pathways and induction of subsequent immune responses. Here, we report biochemical evidence that 6-shogaol, the most bioactive component of ginger, inhibits lipopolysaccharide-induced dimerization of TLR4 resulting in the inhibition of $NF-{\kappa}B$ activation and the expression of cyclooxygenase-2. Furthermore, we demonstrate that 6-shogaol can directly inhibit TLR-mediated signaling pathways at the receptor level. These results suggest that 6-shogaol can modulate TLR-mediated inflammatory responses, which may influence the risk of chronic inflammatory diseases.

• Journal of Yeungnam Medical Science
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• v.38 no.4
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• pp.366-370
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• 2021

Immune checkpoint inhibitors (ICIs) have become the main drugs for programmed cell death receptor-1 or ligand-1 expressing non-small cell lung cancer (NSCLC) combined with conventional chemotherapy. ICIs are generally more tolerable than cytotoxic chemotherapies in terms of toxicity, and ICI-related adverse events are mild and manageable. However, these drugs may lead to unexpected severe adverse events such as immune-related hematologic toxicities, which could be life-threatening. Here, a rare case of a pembrolizumab-related adverse event in a patient with NSCLC who showed early-onset hemolytic anemia and recovered by high-dose steroid and a series of plasma exchanges is reported.

• Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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• 2019.05a
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• pp.296-297
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• 2019

An effective crisis management system capable of responding early in the event of a major disaster or cyber crisis is needed not only within the organization but also with the partner organizations and the outside. In this paper, we review the domestic and international countermeasures against major disasters and cyber crises, and discuss the emerging crisis responses and future prospects along with the development of ICT technology.

• The Bulletin of The Korean Astronomical Society
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• v.44 no.1
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• pp.62.3-62.3
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• 2019

After first identification of electromagnetic counterpart of gravitational wave source (GW170817), era of multi-messenger astronomy has begun. For specifying coordinate, magnitude, and host galaxy information, optical follow-up observation of GW source becomes important. With following engineering run and O3 run of LIGO and VIRGO starting in March 2019, we present searching strategy for optical counterpart of GW source using KMTNet. 24 hours monitoring system and large field of view (4 square-degree) of KMTNet are advantage to discover a transient like GW event. By performing tiling observation of high probability area in GW localization map, we expect to observe early light-curve of GW optical counterpart. After identification, follow-up observation with various KMTNet bands and other telescopes like Gemini and UKIRT will also be performed. We will study collision mechanism, progenitor, and characteristics of host galaxy using observation data of GW source.

• Proceedings of the PSK Conference
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• 2003.10b
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• pp.71.1-71.1
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• 2003

We show that Cdc6, an essential initiation factor for DNA replication, undergoes caspase-3-mediated cleavage in the early stages of apoptosis in HeLa cells and SK-HEP-1 cells induced by etoposide, paclitaxel, ginsenoside Rh2, or TRAIL. The cleavage occurs at the SEVD$\^$442//G motif and generates an N-terminal truncated Cdc6 fragment (p49-tCdc6) that lacks the carboxy-terminal nuclear export sequence (NES). Cdc6 is known to be phosphorylated by cyclin A-Cyclin A-dependent kinase 2 (Cdk2), an event that promotes its exit from the nucleus and probably blocks it from initiating inappropriate DNA replication. (omitted)