• Proceedings of the Korean Society of Tribologists and Lubrication Engineers Conference
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• 1996.04b
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• pp.126-132
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• 1996

A laboratory scale hot strip rolling wear simulator(HRWS) was developed for the purpose of investigating the tribological phenomena occurred in production hot strip rolling mills. The HRWS' main parts are the electric heater, the mechanical descaler, tandem type 2-4Hi rolling mill stands, the cooling chamber, the tension controller and coiler. By simulating the tribelogical phenomena in rolling process at laboratory, wear patterns, cracks, cat-ear wear, black film, effect of hot rolling oil lubrication, etc. were reproduced, and discussed on the performace of simulator.

• Proceedings of the Korean Biophysical Society Conference
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• 1997.07a
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• pp.21-21
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• 1997

Transport of drug entrapped in a liposome-hydrogel formulation was significantly retarded in an in vitro topical application. Liposomes containing hydrocortisone acetate, a hydrophobic antiinflammatory agent, were prepared by the precipitation method, and the liposomal suspension was mixed with hydrogel into a semisolid gel-type ointment.(omitted)

• Journal of the Korean Society of Clothing and Textiles
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• v.19 no.6
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• pp.1027-1039
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• 1995

Clothing fitness is strongly required in the apparel industry, and draping is an effective tool to increase fitness to the wearers. A more sophisticated and systematic information of the somatotype, accordingly, is necessary for better cress form design. This study was performed to provide fundamental data on middle aged women's upper torso for dress form designers and pattern makers by classifying the somatotype based on each individual's lateral view, and analyzing the characteristics of their somatotype. Data were analyzed by factor analysis, cluster analysis, analysis of variance. Factor analysis was used to 23 items from photometric measurment and cluster analysis was applied for classification of upper torso forms. Through cluster analysis using 5 factor scores, 3 somatotypes were categorized from th lateral view 1) Type I was straight somatotype in which the plumb line passes throught the lobe of the ear, the shoulder joing and the mid abdominal region laterally. This type of woman was slender and shorter than average. 2) Type II was bending somatotype in which the upper portion of upper torso is bent forward. This type of woman was taller and fatter than average. 3) Type III was swayback somatotype in which the upper portion of protruding point on the back is bent forward but the lower portion of protruding point had characteristic of turning over somatotype. This type of woman had storter length on the front and longer lenght on the back, slender type and flat chest.

• The Journal of Pediatrics of Korean Medicine
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• v.28 no.3
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• pp.59-73
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• 2014

Allergic contact dermatitis (ACD) is a type IV delayed hypersensitivity reaction that results from exposures and subsequent sensitization to an environmental chemical. Crataegus Pinnatifida (CP) is commonly used to improve spleen function, remove retention of food, and promote blood circulation. This study is designed to investigate the effects of CP on ACD induced by 2,4-dinitrochlorobenzene (DNCB) in mice. In this experiment, the effects of CP on changes in body weights, ear and dorsum skin thicknesses, ear weights, clinical aspects on the dorsum skin, histopathological changes, spleen weights, cytokines were investigated. In addition, the effects on the proliferation rates of splenocytes were also investigated in vivo and vitro study. In results, CP spread (CPS) group and CP spread and administered (CPS+Adm) group showed decrease in spleen weights. In CPS+Adm group, dorsum skin thicknesses were decreased significantly compared to control group. CP treatment diminished erythema, desquamation and keratosis which were induced by repeated painting of DNCB. In histopathological observation, spongiosis and edema were diminished in CPS and CPS+Adm group. CP led to decrease in the proliferation rates of splenocytes in vivo and vitro. In conclusion, these data suggest that CP can decrease symptoms of ACD, so CP is useful to treat patient with ACD.

• Biomedical Science Letters
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• v.20 no.4
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• pp.201-208
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• 2014

This study was conducted to investigate hypoacusis due to workplace noise among dental technicians. Pure tone audiometry, impedance audiometry and heart rate variability were measured for 60 dental technicians and office workers in D city from July to November 2013, and a survey on the effects of noise was conducted. SPSS 19.0 was used for statistical analysis. In the result for threshold of pure tone audiometry, the average hearing threshold of left ears in the air conduction (AC) test showed a statistically significant decrease (P=0.019) among dental technicians, who are frequently exposed to workplace noise. The hearing threshold in the AC test for each frequency was significantly different between the two groups at 125 Hz (P=0.012) in right ears and at 1 kHz (P=0.022), 2 kHz (P=0.040), and 8 kHz (P=0.018) in left ears. Dental technicians who had worked for 16 years or longer had a significantly higher incidence of hypoacusis in the right ear (P=0.030) and in the left ear (P=0.010). In impedance audiometry showed a tympanometry result of type A in both the dental technician group and the office worker group.

• Archives of Pharmacal Research
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• v.29 no.6
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• pp.503-507
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• 2006

Flavonoids are known as natural anti-inflammatory agents. In this investigation, an anti-inflammatory potential of new topical preparation (SK Ato $Formula^{\circledR}$) containing flavonoid mixtures from Scutellaria baicalensis Georgi roots and Ginkgo biloba L. leaves with an extract of Gentiana scabra Bunge roots was evaluated in an animal model of chronic skin inflammation. Multiple 12-O-tetradecanoylphorbol-13-acetate treatments for 7 consecutive days on ICR mouse ear provoked a chronic type of skin inflammation: dermal edema, epidermal hyperplasia and infiltration of inflammatory cells. When topically applied in this model, this row formulation $(5-20\;{\mu}L/ear/treatment)$ reduced these responses. Furthermore, it inhibited prostaglandin $E_2$ generation (17.1-33.3%) and suppressed the expression of proinflammatory genes, cyclooxygenase-2 and $interleulin-1{\beta}$ in the skin lesion. Although the potency of inhibition was lower than that of prednisolone, all these results suggest that Ato $Formula^{\circledR}$ may be beneficial for treating chronic skin inflammatory disorders such as atopic dermatitis.

• Proceedings of the KOSOMBE Conference
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• v.1996 no.05
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• pp.243-247
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• 1996

Electro-magnetic type implantable middle ear hearing aid has been empirically developed. But for further improvement of the system performance more quantitative approach is necessary. In this paper, we analyzed vibrating transducer which is most important to design the system, appropriate for given hearing level, and implemented it. Using this transducer, implantable hearing aid system are developed. To verify the design process, we experimented with driving metal strip by the developed system. From the experiment, frequency response of implemented device showed good characteristic at audio frequency and we confirmed that each part of the developed system operated well.

• Parasites, Hosts and Diseases
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• v.51 no.1
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• pp.69-74
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• 2013

Leishmania tropica is one of the causative agents of leishmaniasis in humans. Routes of infection have been reported to be an important variable for some species of Leishmania parasites. The role of this variable is not clear for L. tropica infection. The aim of this study was to explore the effects of route of L. tropica infection on the disease outcome and immunologic parameters in BALB/c mice. Two routes were used; subcutaneous in the footpad and intradermal in the ear. Mice were challenged by Leishmani major, after establishment of the L. tropica infection, to evaluate the level of protective immunity. Immune responses were assayed at week 1 and week 4 after challenge. The subcutaneous route in the footpad in comparison to the intradermal route in the ear induced significantly more protective immunity against L. major challenge, including higher delayed-type hypersensitivity responses, more rapid lesion resolution, lower parasite loads, and lower levels of IL-10. Our data showed that the route of infection in BALB/c model of L. tropica infection is an important variable and should be considered in developing an appropriate experimental model for L. tropica infections.

• Journal of Korean Physical Therapy Science
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• v.16 no.2
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• pp.11-17
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• 2009

Background: The purpose of this study was to investigate the effects of the body alignment on the type and weight of the bag. Methods: The Subjects(n=62) measured posture alignment and make out the questionnaire. The questionnaire item was type of the bag, weight of the bag, side which carries the bag, and time to carry the bag. The posture alignment measured by global posture system(GPS). GPS Measurement was ASIA, acromion process, medial malleolus on Frontal plane, ear, shoulder joint, knee joint, lateral malleolus on sagittal plane, and trunk rotation on transverse plane. Results: The backpack and shoulder bag was no significant. The width of the strap bag was not significant. The side which carries on shoulder bag was statistical significance(p<.05). The time to carry the bag was statistical significance on change of posture(p<.05). A bag weight was no significant. Conclusion: This research provides the direction and carry the bag in time for the posture. This study showed that type and weight of bag does affect body alignment. This indicates that there is an interaction that plays a crucial roles in the type and weight of bag and the body alignment.

• Proceedings of the Korean Society of Embryo Transfer Conference
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• 2002.11a
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• pp.75-75
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• 2002

The present study was conducted for the production of transgenic cloned cows by somatic cell nuclear transfer (SCNT) that secrete human prourokinase into milk. To establish an efficient production system for bovine transgenic SCNT embryos, the offset was examined of various conditions of donor cells including cell type, size, and passage number on the developmental competence of transgenic SCNT embryos. An expression plasmid far human prourokinase (pbeta-ProU) was constructed by inserting a bovine beta-casein promoter, a green fluorescent protein (GFP) marker gene, and a human prourokinase target gene into a pcDNA3 plasmid. Three types of bovine somatic cells including two adult cells (cumulus cells and ear fibroblasts) and fetal fibroblasts were prepared and transfected using a lipid-meidated method. In Experiment 1, developmental competence and rates of GFP expression in bovine transgenic SCNT embryos reconstructed with cumulus cells were significantly higher than those from fetal and ear fibroblasts. In Experiment 2, the effect of cellular senescence in early (2 to 4) and late (8 to 12) passages was investigated. No significant differences in the development of transgenic SCNT embryos were observed. In Experient 3, different sizes of GFP-expressing transfected cumulus cells [large (>30 ${\mu}{\textrm}{m}$) or small cell (<30 ${\mu}{\textrm}{m}$)] were used for SCNT. A significant improvement in embryo development and GFP expression was observed when small cumulus cells were used for SCNT. Taken together, these results demonstrate that (1) adult somatic cells could serve as donor cells in transgenic SCNT embryo production and cumulus cells with small size at early passage were the optimal cell type, and (2) transgenic SCNT embryos derived from adult somatic cells have embryonic development potential.