• 대한치주과학회:학술대회논문집
• /
• 1998.11a
• /
• pp.38-38
• /
• 1998

• 대한치주과학회:학술대회논문집
• /
• 1998.11a
• /
• pp.37-37
• /
• 1998

• Proceedings of the CALSEC Conference
• /
• 2002.01a
• /
• pp.201-208
• /
• 2002

사전에 정의된 일정한 규칙과 절차에 따라, 한사람에서 다른 사람에게 전달되는 과제 및 정보의 흐름을 자동화하는 시스템[WfMC] 정의된 업무와 관련된 사람, 정보 자원의 흐름을 통합적으로 관리, 지원해주는 업무처리 자동화 시스템(중략)

• Proceedings of the Korean Society of Food and Cookery Science Conference
• /
• 2004.10a
• /
• pp.103-103
• /
• 2004

• Kyungpook Mathematical Journal
• /
• v.33 no.1
• /
• pp.91-99
• /
• 1993

• Proceedings of the Korean Nutrition Society Conference
• /
• 2003.10a
• /
• pp.101-101
• /
• 2003

• Toxicological Research
• /
• v.16 no.2
• /
• pp.95-100
• /
• 2000

In previous study, both constitutive expression and 3-methylcholanthrene (3MC)-mediated elevation of CYP1A2 mRNA were demonstrated in human hepatoma HepG2 cells by reverse transcription-polymerase chain reaction (RT-PCR), suggesting that HepG2 cells would be appropriate for the study of human CYP1A2 regulation(Chung and Bresnick, 1994). Further studies were conducted to determine the basis of this induction phenomenon that is observed in HepG2 cells. Since CYP1A1 gene, another polycyclic hydrocarbon(PH)-inducible gene, is regulated by PHs through their interactions via receptors with cis-elements, the 5'-flanking region of human CYP 1A2 gene was analyzed to search such responsive elements. The promoter activity of various lengths of CYP1A2 gene sequence (-3203/+58bp) was measured in transiently-transfected HepG2 cells by fusion constructs containing the CAT, hGH or luciferase genes as a reporter. This region of the CYP1A2 gene, although containing a XRE, was only weakly responsive (less than 2 fold induction) to 10 nM of TCDD or 1 $\mu$M 3 MC treatment. This small enhancement of promoter activity is inconsistent with the previous observation, i.e., 12 to 14 fold-enhanced CYP1A2 mRNA from 1 $\mu$M 3 MC treated HepG2 cells, suggesting that additional mechanisms would exist for PH-mediated induction of CYP1A2 in these cells.

• Journal of the Korean Institute of Electrical and Electronic Material Engineers
• /
• v.18 no.3
• /
• pp.276-283
• /
• 2005

Magnetic tunneling transistor (MTT) device using the amorphous n-type Si semiconductor film for base and collector consisting of the [CoFe/NiFe](free layer) and Si(top layer) multilayers was used to study the spin-dependent hot electron magnetocurrent (MC) and tunneling magnetoresistance (TMR) at room temperature. A large MC of 40.2 % was observed at the emitter-base bias voltage ( $V_{EB}$ ) of 0.62 V. The increasing emitter hot current and transfer ratio ( $I_{C}$/ $I_{E}$) as $V_{EB}$ are mainly due to a rapid increase of the number of conduction band states in the Si collector. However, above the $V_{EB}$ of 0.62 V, the rapid decrease of MC was observed in amorphous Si-based MTT because of hot electron spin-dependent elastic scattering across CoFe/Si interfaces.

• Korean Journal of Air-Conditioning and Refrigeration Engineering
• /
• v.5 no.3
• /
• pp.198-206
• /
• 1993

Experimental results of two stage Gifford-McMahon cryorefrigerator are described. In-prototype experiments, drive mechanism is Scotch Yoke type driven by stepping motor, copper meshes and lead balls are used for regenerator's materials in the first stage and the second stage, respectively. To find optimal conditions of the cryopump, no load temperature and refrigeration capacity according to the variation of cycle frequency and operating pressure are measured, and the cool down and load characteristics at particular cycle frequencies are presented. In general, as the cycle frequency is lowered, no load temperature is dropped but refrigeration capacity is diminished. As the representative result, in a case that the cycle frequency is 70rpm and steady state pressure is 14 atm, no load temperature of second stage is lowered to 10.5K in 55 minuters, and in this situation the refrigeration capacity of the first stage is 42W at 80K, that of the second stage is 11 W at 20K.

• Journal of Oriental Neuropsychiatry
• /
• v.21 no.2
• /
• pp.29-44
• /
• 2010

Objectives : The purpose of this study was to investigate the effect of Gentianae Radix on neurogenesis and apoptosis in ethanol- induced newborn rats hippocampus dentate gyrus. Methods : In vivo, laboratory animals were divided into three groups; Normal group(N), Control group(C) and Treated group (TG)(n=7 for each group). N were treated saline daily for five days. C were treated 1.5 g/kg ethanol and saline daily for five days. TG were treated 1.5 g/kg ethanol and 300 mg/kg Gentianae Radix daily for five days. BrdU(5-bromo-2-deoxyuridine) assay was used to test neurogenesis in the dentate gyrus. And TUNEL(Terminal deoxynucleotidyl transferase dUTP nick end labeling) assay was used to test apoptosis in the dentate gyrus. Three groups were measured body weight, serum ethanol concentration, BrdU-positive cells and TUNEL-positive cells in the dentate gyrus. In vitro, MTT(3-(4,5-Dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide) assay was used to test viability in SK-N-MC cells. BrdU assay was used to test neurogenesis in SK-N-MC cells. DNA fragmentation and caspase-3 enzyme activity assay were used to test apoptosis in SK-N-MC cells. And treated ethanol and Gentianae Radix of all in vitro tests were made various concentration. Results : In vivo, Gentianae Radix modulated ethanol-induced neurogenesis and apoptosis in newborn rats hippocampus dentate gyrus. In vitro, TG 100 ${\mu}g/ml$ have significantly modulated ethanol-induced neurogenesis and apoptosis in SK-N-MC cells. And only TG 100 ${\mu}g/ml$ have significantly protected SK-N-MC cells from ethanol-induced cytotoxicity. Conclusions : Gentianae Radix may have the effect that modulated ethanol-induced neurogenesis and apoptosis in SK-N-MC cells.