• Title/Summary/Keyword: eIF4E

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Study on the Sex Chromosome Dependent Segregation of the Third Chromosome in Drosophila melanogaster (초파리의 성 옆색체의 구성이 제 3옆색체의 분리에 미치는 영향에 대하여)

  • Kang, M.J.;Kang, S.J.;Chung, Y.J.
    • The Korean Journal of Zoology
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    • v.13 no.1
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    • pp.15-20
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    • 1970
  • The present study was undertaken in an attempt to see if the segregation frequency of a third chromosome was changed by changing the sex chromosome which were free of SD in the second chromosome. The eight genotype males having different sex chromosome constitution each were constructed by appropriate matings and the two standard laboratory stocks of Drosophila melanogaster, e and se were used as the third chromosome recessive markers for the present experiment. The results of the present investigation are given below: 1. The k values which are the proportion of the se third chromosomes recovered among progeny flies from the mating of se/e males to e females were highly signiicantly different among the four genotypes and between the two sexes,and the interaction of genotype and sex was significantly different. Thus the setregation frequency of the se third chromosome in the male, when made heterozygous with the e third chromosome, was dependent upon the sex chromosome constitution. 2. Both of the k(Woman) and the k(man) remains roughly constant among genotypes. 3. The sex ratio o the se progeny class was highly significantly heterogeneous among the four genotypes but it was homogeneous for the e progeny class. 4. The values of the k(man) and the sex ratio of the se progeny class, on the average, were higher than that of the k(Woman) and of the e progeny class, respectively. 5. Those phenomena suggest that some sort of prezygotic selection could be operating such that the combination of the e third chromosome and the Y chromosome tends to be eliminated before fertilization. This tendency argues for a re-examination of the viability estimations of Drosophila melanogaster.

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Can distinction between the renal cortex and outer medulla on ultrasonography predict estimated glomerular filtration rate in canine chronic kidney diseases?

  • Lee, Siheon;Hong, Sungkyun;Kim, Seungji;Oh, Dayoung;Choen, Sangkyung;Choi, Mincheol;Yoon, Junghee
    • Journal of Veterinary Science
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    • v.21 no.4
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    • pp.58.1-58.11
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    • 2020
  • Background: Quantitative evaluation of renal cortical echogenicity (RCE) has been tried and developed in human and veterinary medicine. Objectives: The objective of this study was to propose a method for evaluating RCE quantitatively and intuitively, and to determine associations between ultrasonographic renal structural distinction and estimated glomerular filtration rate (eGFR) in canine chronic kidney disease (CKD). Methods: Data were collected on 63 dogs, including 27 with normal kidney function and 36 CKD patients. Symmetric dimethylarginine and creatinine concentrations were measured for calculating eGFR. RCE was evaluated as 3 grades on ultrasonography images according to the distinction between the renal cortex and outer medulla. The RCE grade of each kidney was measured. Results: There was a significant difference in eGFR between the group normal and CKD (p < 0.001). As mean of RCE grades (the mean values of each right and left kidney's RCE grade) increases, the proportion of group CKD among the patients in each grade increases (p < 0.001). Also, severity of RCE (classified as "high" if any right or left kidney evaluated as RCE grade 3, "low" otherwise) and eGFR is good indicator for predicting group CKD (p < 0.001). Conclusions: The degree of distinction between the renal cortex and the outer medulla is closely related to renal function including eGFR and the RCE grade defined in this study can be used as a method of objectively evaluating RCE.

Painterly rendering using density of edges (에지 밀도 정보를 이용한 회화적 렌더링)

  • Lee, Ho-Chang;Park, Young-Sup;Seo, Sang-Hyun;Yoon, Kyung-Hyn
    • Journal of the Korea Computer Graphics Society
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    • v.12 no.4
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    • pp.7-15
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    • 2006
  • The ultimate objective of painterly rendering is to express an inputted image as if it is hand drawn. The factors to express this painterly effect are thickness of the brush, direction, texture and the establishment of criteria judging if the produced brush will be drawn on to the canvas. In this paper, the algorithm using density of the edges in determining the criteria whether the brush will be drawn onto the canvas is proposed. Density of edges refers to the quantity of edge in the specific area. And uses the method of finding the location of the brush to be drawn as a unit of dynamic grid as well as expressing consistent directional through direction interpolation. Also, the texture is expressed using various textured brushes. Considering density of edges,We can express detailed area and abstract area. And it result in more human effect of oil painting.

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Establishment of Human-Mouse Chimeric Animal by Injecting Human Embryonic Stem Cells into Mouse Blastocoele Cavity

  • 윤지연;이영재;김은영;이훈택;정길생;박세필;임진호
    • Proceedings of the KSAR Conference
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    • 2003.06a
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    • pp.77-77
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    • 2003
  • Chimeric animals are referred to as an organism composed of tissues derived from more than one species. In order to examine if a pluripotency of embryonic stem cells can cross the limitation of a species, we tried to establish human-mouse chimeric animals. Human embryonic stem cells were genetically modified to express eGFP using eukaryonic expression vector pcDNA 3.1 (In Vitrogene) for an easy identification. After selection with neomycin, approximately 15 cells were implanted into mouse blastocoele cavity. Ten chimeric blastocysts were transferred to one of the uterine horn of 2.5 days pesudopregnent ICR female. Out of 272 blastocysts transferred to pseudopregnant recipients 20 live newborn were obtained after 20 days. When newborn were obtained, pups were quickly removed immersed into 4% PFA. By histological examination using fluorescent microscope, green fluorescence was observed from the liver, heart, and spleen in newborn mice. Three weeks after born, presence of eGFP sequence within mouse genome (tail and kidney) was reconfirmed by PCR. eGFP sequence was amplified from the progenies of the animal suggesting a genetic transmission of the transgene. These chimeric mice having human cells at the beginning of development, are expected to recognize human cells as “self”, therefore, human cells or tissues will be able to escape the immunological surveillance of the host if grafted into the animal. These animals will serve as a good model system for studying the graft rejection in tissue transplantation and the potential of the cells to work well in many human disease.

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The Design of repeater U-shaped Antenna for ship base station Applications (선박기지국 응용을 위한 중계기용 U형 급전 안테나 설계)

  • Park, Chang-Hyun;Kim, Young-Nam;Kim, Kab-Ki
    • Proceedings of KOSOMES biannual meeting
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    • 2007.11a
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    • pp.211-214
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    • 2007
  • In this paper, we have designed microstrip antenna if 800[MHz] band It will be able to integrate TRS(Trunked Radio System), GSM(Global System for Mobile telecommunication) band including the CDMA(Code Division Multiple Access) band we designed repeater and a base station antenna which is possible at the ship and marine of safety. It is improves a narrow bandwidth problem of microstrip antenna. It had U-shaped feeding structure at a rectangular patch And ground or feeding structure used between dielectric constant(${\varepsilon}_T$ = 2.1), patch or feeding structure used between dielectric constant(${\varepsilon}_T$ =1). So it used a duplex resonance effect Designed frequency bandwith(V5WR 2:1) if the antenna showed good characteristic of $780[MHz]{\sim}1.83[GHz]$ to 2.61[GHz]. Also the E-plan and H-plan all profit 9.4[dBi] above, the 3[dB] beam width showed the characteristic over the E-plan and H-plan $60^{\circ}$ to be improved.

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CHARACTERIZATIONS OF GAMMA DISTRIBUTION

  • Lee, Min-Young;Lim, Eun-Hyuk
    • Journal of the Chungcheong Mathematical Society
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    • v.20 no.4
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    • pp.411-418
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    • 2007
  • Let $X_1$, ${\cdots}$, $X_n$ be nondegenerate and positive independent identically distributed(i.i.d.) random variables with common absolutely continuous distribution function F(x) and $E(X^2)$ < ${\infty}$. The random variables $X_1+{\cdots}+X_n$ and $\frac{X_1+{\cdots}+X_m}{X_1+{\cdots}+X_n}$are independent for 1 $1{\leq}$ m < n if and only if $X_1$, ${\cdots}$, $X_n$ have gamma distribution.

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REEB FLOW SYMMETRY ON ALMOST COSYMPLECTIC THREE-MANIFOLDS

  • Cho, Jong Taek
    • Bulletin of the Korean Mathematical Society
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    • v.53 no.4
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    • pp.1249-1257
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    • 2016
  • We prove that the Ricci operator S of an almost cosymplectic three-manifold M is invariant along the Reeb flow, that is, M satisfies ${\pounds}_{\xi}S=0$ if and only if M is either cosymplectic or locally isometric to the group E(1, 1) of rigid motions of Minkowski 2-space with a left invariant almost cosymplectic structure.

ON CHARACTERIZATIONS OF THE NORMAL DISTRIBUTION BY INDEPENDENCE PROPERTY

  • LEE, MIN-YOUNG
    • Journal of applied mathematics & informatics
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    • v.35 no.3_4
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    • pp.261-265
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    • 2017
  • Let X and Y be independent identically distributed nondegenerate random variables with common absolutely continuous probability distribution function F(x) and the corresponding probability density function f(x) and $E(X^2)$<${\infty}$. Put Z = max(X, Y) and W = min(X, Y). In this paper, it is proved that Z - W and Z + W or$(X-Y)^2$ and X + Y are independent if and only if X and Y have normal distribution.

A Study on the Emission Characteristics and Prediction of VOCs (Volatile Organic Compounds) using Small Chamber Method (소형챔버법을 이용한 휘발성유기화합물(VOCs) 방출특성 및 예측에 관한 연구)

  • Pang, Seung-Ki;Sohn, Jang-Yeul;Lee, Kwang-Ho
    • KIEAE Journal
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    • v.4 no.4
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    • pp.11-18
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    • 2004
  • In this study, the measurement system was developed for the measurement of pollutants from building materials, and specimens were made with concrete, gypsum board, mortar and wall paper. Characteristics of VOCs and TVOC concentration and Emission Factor as a function of time were assessed, and the conclusion was drawn as follows. (1) From predicting TVOC concentration decrease of specimen 7 with the wall paper attached to the concrete, the graph may become linear by converting the value of y-axis into the log function, and the prediction equation can be expressed as $y=34906{\ast}e^{-0.0093{\ast}time}$. Moreover, chi-square value was 0.83 which is relatively high value, indicating that TVOC concentration can be properly predicted if the same materials are used indoors. (2) From predicting VOCs Emission Factor decrease of specimen 7, the prediction equation can be expressed as $EF=15111{\ast}e^{-0.0093{\ast}time}$, and chi-square value was 0.83. (3) From predicting TVOC concentration decrease of specimen 7, prediction equation can be considered to be $y=254323{\ast}(1-e^{-0.1046{\ast}time})$, and chi-square was 0.994 which is significantly high value, indicating that indoor TVOC concentration can be properly predicted if the same materials are used indoors. Furthermore, the prediction of concentration decrease using cumulative value of hourly measured concentration is considered to be more accurate than that using just hourly measured value directly. (4) From predicting Emission Factor decrease with cumulative hourly data of Emission Factor, chi-square appeared to be higher than that by just using hourly data of Emission Factor directly. Therefore, the prediction of Emission Factor with cumulative hourly data can provide more reliable prediction equation than the case by using just hourly concentration directly.

Performance Analysis of a Sleep Mode Operation in the IEEE 802.16e Wireless MAN with M/G/1 Multiple Vacations Model (M/G/1 복수 휴가 모델을 이용한 IEEE 802.16e 무선 MAN 수면모드 작동에 대한 성능분석)

  • Jung, Sung-Hwan;Hong, Jung-Wan;Chang, Woo-Jin;Lie, Chang-Hoon
    • Journal of the Korean Operations Research and Management Science Society
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    • v.32 no.4
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    • pp.89-99
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    • 2007
  • In this paper, an analytic model of a sleep mode operation in the IEEE 802.16e is investigated. A mobile subscriber station(MSS) goes to sleep mode after negotiations with the base station(BS) and wakes up periodically for a short interval to check whether there is downlink traffic to it. If the arrival of traffic is notified, an MSS returns to wake mode. Otherwise, it again enters increased sleep interval which is double as the previous one. In order to consider the situation more practically, we propose the sleep mode starting threshold, during which MSS should await packets before it enters the sleep mode. By modifying the M/G/l with multiple vacations model, energy consumption ratio(ECR) and average packet response time are calculated. Our analytic model provides potential guidance in determining the optimal parameters values such as sleep mode starting threshold, minimal sleep and maximal sleep window.