• 한국임상수의학회지
• /
• 제14권1호
• /
• pp.11-18
• /
• 1997

This study was performed to make fundamental data of ultrasonographic diagnosis for liver and duodenum disease in native Korean cattle. Ultrasonographic appearance of liver, caudal vena cava, portal vein, gall bladdr and duodenum according to the growth were determined from 6 to 13 months by monthly examinations in 9 native Korean cattle. The caudal vena cava was determined at 11th intercostal space by use of ultrasonography. The portal vein and gallbladder were determined at 10th intercostal space by use oof ultrasonography. The liver were determined at 12, 11 and 10 th intercostal space by use of ultrasonography. The liver, caudal vena cava, portal cein, gallbladder and duodenum were examinde in standing position. Ultrasonograms were obtainde with 3.5 or 5.0-MHz convex and 5.0-MHz sector transducer. The diameter of vena cava at the 6, 7, 8, 9, 10, 11, 12 and 13 months old age were 18.4, 20.6, 22.4, 25.1, 26.9, 27.3, 28.5 and 29.4 mm, respectively. The diameter of portal vein at the 6, 7, 8, 9, 10, 11, 12 and 13 months old age were 19.5, 20.6, 22.3, 24.5, 26.9, 28.1, 30.7 and 31.5 mm, respectively. The diameter of gall bladder at the 6, 7, 8, 9, 10, 11, 12 and 13 months old age were 63.2, 72.2, 75.1, 78.6, 80.5, 82.3, 84.4 and 91.1 mm, respectively. Cranial part of duodenum was identified near gall bladder by moving of hyperechoic ingesta. Descending duodenum paralleled with vertebrae is seen in the right upper flank and was adjacent to the abdominal wall, and was enveloped in the hyperechoic greater omentum, differentiating it from the jejunum and ileum. The diameter of cranial duodenum at the 6, 7, 8, 9, 10, 11, 12 and 13 months old age were 23.3, 27.9, 29.9, 32.2, 34.4, 34.5, 35.1 and 36.5 mm, respectively. The diameter of descending duodenum revealed smaller diameter than that of cranial duodenum. Calculi in gallbladder were observed by ultrasonography.

• 대한약리학회지
• /
• 제9권2호
• /
• pp.47-53
• /
• 1973

Chinae Rhizoma is dried crude roots and rhizomes obtained from Smilax china Linne which belongs to Smilax Genus of Liliaceae Familia, and it has been in wife use as a folk remedy for a long time. But very little systemic studies on its pharmacological actions have been made until now. Furthermore, the effective components except saponin of Chinae Rhizoma have been not known yet. It came to the attention of the authors that Chinae Rhizoma are used as antidiarrhetics in Chinese herb medicine, therefore they attempted to observe the effects of Chinae Rhizoma Alcoholic Extracts (Chinae Rhizoma Ethanol Extract=CREE, Chinae Rhizoma Methanol Extract=CRME) from Smilax china Linne on motility of the isolated rabbit duodenum in this experiment. The results of the study were as follow: 1. The movement of the isolated rabbit duodenum was slowed down and its tonus was relaxed in proportion to the concentration of Chinae Rhizoma Alcoholic Extracts (CREE & CRME). 2. With a concentration of CREE $10^{-4}g/ml$, the contractile effects of acetylcholine $10^{-6}g/ml$, pilocarpine $10^{-5}g/ml$ and physostigmine $10^{-5}g/ml$ were remarkably blocked in the movement of isolated rabbit duodenum. 3. The concentration of the isolated rabbit duodenum induced by barium chloride $10^{-4}g/ml$ was significantly inhibited by CREE $10^{-4}g/ml$. 4. With the administrations of histamine $10^{-5}g/ml$, serotonin $10^{-6}g/ml$ and prostaglandin $A_2\;10^{-6}g/ml$ respectively, contractions were observed in the rabbit duodenum. But, treatment of CREE $10^{-4}g/ml$ inhibited markedly the tonus and motility of the duodenum pretreated with the above drugs. 5. The effects of CREE and CRME were very much alike in this experiment. From the above results, it is concluded that the mechanism of action of Chinae Rhizoma on motility of isolated rabbit duodenum was partially due to cholinergic blocking effect.

• 약학회지
• /
• 제29권3호
• /
• pp.111-116
• /
• 1985

Effect of sodium-5-methoxysalicyclate (5MSA-Na) on the absorption of cefmetazol (CMZ) was studied in rectum and duodenum of rats via in situ loop method. Effect of 5MSA-Na on the absorption of CMZ showed markedly different results in rectum and duodenu. Penetration of 5MSA-Na was greater in rectum than in duodenum and water-transfer was markedly increased in duodenum.

• 대한수의학회지
• /
• 제37권2호
• /
• pp.445-450
• /
• 1997

The purpose of this study is to determine the changes of ultrasonographic appearance of stomach, pylorus and duodenum in relation to food intake and administration of contrast medium in dogs. Ultrasonograms were obtained with 5.0MHz sector transducer. After placing the dogs in dorsal recumbency, scanning was performed at the 8th intercostal space. The mean inner diameter of stomach immediately after food intake, 2, 4 and 6 hours was 47.9, 51.5, 46.8 and 40.6mm, respectively. The diameter of pylorus immediately after food intake, 2, 4 and 6 hours was 7.4, 9.7, 8.9 and 6.0mm, respectively(p<0.01). The diameter of duodenum immediately after food intake 2, 4 and 6 hours was 12.5, 7.9, 11.9 and 11.8mm, respectively(p<0.01). Before administration of contrast medium, the mean inner diameter of stomach, pylorus and duodenum was 38.6, 7.2 and 9.5mm, respectively. After administration of contrast medium, the diameters of stomach, pylorus and duodenum was 42.8, 7.7 and 9.9mm, respectively. It may be concluded that the ultrasonographic values determined in this study can be used as references for the diagnosis of gastrointestinal disease in dogs.

• Journal of Digestive Cancer Research
• /
• 제11권1호
• /
• pp.49-54
• /
• 2023

Colorectal cancers often invade adjacent organs; however, direct duodenal invasion is rare. Adenocarcinoma is the most common type of colorectal cancer, but an undifferentiated carcinoma type is unusual. Herein, we present a case of undifferentiated carcinoma of the colon that directly invaded the duodenum and metastasized to distant lymph nodes. An 85-year-old female patient was admitted with a 7-cm-sized colonic mass invading the duodenum, detected by computed tomography. Positron emission tomography revealed fluorodeoxyglucose uptake in the colon, duodenum, and aortocaval lymph nodes. A large encircling mass in the ascending colon and an ulcerated mass in the duodenum were revealed by colonoscopy and esophagogastroduodenoscopy, respectively. Pathologic examinations of the colon and the duodenum revealed nonglandular, diffusely infiltrating atypical round cells, confirming undifferentiated carcinoma of the colon. The histologic type of this tumor was distinguished using immunohistochemical (IHC) markers. Finally, microscopic characteristics and IHC markers aided in identifying the histologic type of colorectal cancer.

• Journal of Microbiology and Biotechnology
• /
• 제30권2호
• /
• pp.287-295
• /
• 2020

The differences between luminal microbiota (LM) and mucosal microbiota (MAM) were little known, especially in duodenum. In this study, LM and MAM in colon and duodenum of mice were investigated through 16S rRNA high-throughput sequencing. The lowest bacterial diversity and evenness were observed in duodenal LM (D_LM), followed by duodenal MAM (D_MAM). Meanwhile, the bacterial diversity and evenness were obviously increased in D_MAM than these in D_LM, while no significant difference was observed between colonic MAM (C_MAM) and colonic LM (C_LM). PCoA analysis also showed that bacterial communities of LM and MAM in duodenum were completely separated, while these in colon overlapped partly. The ratio of Firmicutes to Bacteroidetes (F/B) in D_MAM was significantly higher than that in D_LM. Lactobacillus was largely enriched and was the characteristic bacteria in D_LM. The characteristic bacteria in D_MAM were Turicibacter, Parasutterella, Marvinbryantia and Bifidobacterium, while in C_LM they were Ruminiclostridium_6, Ruminiclostridium_9, Ruminococcaceae_UCG_007 and Lachnospiraceae_UCG_010, and in C_MAM they were Lachnospiraceae_NK4A136, Mucispirillum, Alistipes, Ruminiclostridium and Odoribacter. The networks showed that more interactions existed in colonic microbiota (24 nodes and 74 edges) than in duodenal microbiota (17 nodes and 29 edges). The 16S rDNA function prediction results indicated that bigger differences of function exist between LM and MAM in duodenum than these in colon. In conclusion, microbiota from intestinal luminal content and mucosa were different both in colon and in duodenum, and bacteria in colon interacted with each other much more closely than those in duodenum.

• The Korean Journal of Physiology
• /
• 제4권2호
• /
• pp.45-51
• /
• 1970

In an attempt to better understand the effect of whole body irradiation on the spontaneous motility and oxygen consumption rate of the isolated mouse duodenum, a whole body X-irradiation of 1,000r. was given to albino mouse, and 1) the total length of contraction of isolated duodenum was recorded on kymograph every five minutes for 60 minutes, 2) glucose and 5-hydroxytryptamine(5-HT) were added to the reaction medium of Kreb's-Ringer-bicarbonate buffer(KRB) and response of the isolated duodenum to the drugs was observed, and 3) the oxygen consumption rate $(QO_2)$ of the isolated duodenum as well as the effect of glucose and 5-HT on $QO_2$ were measured by Warburg's standard manometric method and the comparison was made with the control(i.e. normal) group. The results thus obtained are summarized as follows. 1. The spontaneous motility of the isolated duodenum in the irradiated groups showed a significantly elevated pattern for the first 15 minutes comparing with the control. The motility, however, decreased after 15 minutes and remained so in the irradiated groups to the level of the nonirradiated control, but 24 hours post-irradiation group showed a tendency of an increased motility while one hour post-irradiation group showed no difference comparing with the control. 2. Addition of glucose produced generally elevated motility of the isolated duodenum in both irradiated and non-irradiated groups comparing with the control throughout the experiment, but no difference was observed in contractile amplitude between the irradiated and non·irradiated groups. 3. When 5-HT was added to the irradiated group, the contractile amplitude of isolated duodenum was similar to that of the control, and 5-HT alone caused a slight increase of the motility comparing with the control. 4. The oxygen consumption rate $(QO_2)$ of the isolated duodenum was found to be ,slightly increased in one hour post·irradiated group, but similar in 24 hour post·irradiated group comparing with the control. Glucose produced a significant increase of $QO_2$ in all the groups, but 5-HT produced a tendency of decrease of $QO_2$ in all the groups.

• Asian-Australasian Journal of Animal Sciences
• /
• 제25권10호
• /
• pp.1457-1465
• /
• 2012

Intestinal phosphate (Pi) absorption across the apical membrane of small intestinal epithelial cells is mainly mediated by the type IIb Na-coupled phosphate co-transporter (NaPi-IIb), but its expression and regulation in the chicken remain unclear. In the present study, we investigated the mRNA and protein levels of NaPi-IIb in three regions of chicken small intestine, and related their expression levels to the rate of net phosphate absorption. Our results showed that maximal phosphate absorption occurs in the jejunum, however the highest expression levels of NaPi-IIb mRNA and protein occurs in the duodenum. In response to a low-Pi diet (TP 0.2%), there is an adaptive response restricted to the duodenum, with increased brush border membrane (BBM) Na-Pi transport activity and NaPi-IIb protein and mRNA abundance. However, when switched from a low-(TP 0.2%) to a normal diet (TP 0.6%) for 4 h, there is an increase in BBM NaPi-IIb protein abundance in the jejunum, but no changes in BBM NaPi-IIb mRNA. Therefore, our study indicates that Na-Pi transport activity and NaPi-IIb protein expression are differentially regulated in the duodenum vs the jejunum in the chicken.

• Advances in pediatric surgery
• /
• 제2권1호
• /
• pp.72-76
• /
• 1996

Annular pancreas is a rare congenital anomaly with the descending duodenum encircled by a ring of pancreatic tissue, which may cause partial or complete obstruction of the duodenum. In newborn, the symptoms can be those of duodenal stasis resulting from partial intestinal obstruction secondary to some degree of duodenal stenosis. A male newborn weighing 2.0 Kg was born by C-section delivery at 37 weeks' gestation to a 27-year-old mother who had a hydramnios. He was in relatively good condition at birth except regurgitation of saliva and intermittent apnea. A plain film of the abdomen showed the double-bubble of gas filled stomach and proximal duodenum, and upper gastrointestinal series showed a dilated proximal duodenum, with a complete obstruction of the descending duodenum. Intraoperative finding revealed encirclement of the duodenal second portion by pancreatic tissue. Duodenojejunostomy was performed. After the operation, he had developed two serious complications, neonatal septicemia by Enterobacter cloacae on postoperative day 12 and systemic candidiasis on postoperative day 19, and been managed with ventilatory support, antibiotics, and antifungal agents with recovery.

• 대한수의학회지
• /
• 제26권1호
• /
• pp.19-30
• /
• 1986

Endocrine cells were observed in the gastrointestinal tract of the squirrels by light microscopy using Grimelius and Masson-Hamperl silver impregnation, and in the stomach and duodenum by electron microscopy. Light microscopically, argyrophil cell decreased gradually in number in the pyloric region and ileum, stomach, duodenum and jejunum and rectum in the order listed. Argentaffin cells were moderately distributed in the stomach, pyloric region and duodenum, while absent in the jejunum, ileum and rectum. Five kinds of cell types, EC, ECL, D, $D_1$ and G cells were identified in the stomach and three kinds of cell types, S, $EC_1$ and $EC_2$ were also identified in the duodenum by electron microscopy. A cilium noted in the cytoplasm of $D_1$-type cell. The species differences in the distribution, size and structure of the secretory granules were discussed.