• Title/Summary/Keyword: dual-sampling

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Determination of Appropriate Sampling Frequency and Time of Multiple Blood Sampling Dual Exponential Method with $^{99m}Tc$-DTPA for Calculating GFR (사구체여과율 계산을 위한 $^{99m}Tc$-DTPA를 이용한 다중 채혈 이중지수법의 적정 채혈 횟수 및 시간의 선정)

  • Kim, Chung-Ho;O, Joo-Hyun;Chung, Yong-An;Yoo, Ie-Ryung;Sohn, Hyung-Sun;Kim, Sung-Hoon;Chung, Soo-Kyo;Lee, Hyoung-Koo
    • Nuclear Medicine and Molecular Imaging
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    • v.40 no.1
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    • pp.33-39
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    • 2006
  • Purpose: To determine appropriate sampling frequency and time of multiple blood sampling dual exponential method with $^{99m}Tc$-DTPA for calculating glomerular filtration rate (GFR). Materials & Methods: Thirty four patients were included in this study. Three mCi of $^{99m}Tc$-DTPA was intravenously injected and blood sampling at 9 different times, 5ml each, were done. Using the radioactivity of serum, measured by gamma counter, the GFR was calculated using dual exponential method and corrected with the body surface area. Using spontaneously chosen 2 data points of serum radioactivity, 15 collections of 2-sample GFR were calculated. And 10 collections of 3-sample GFR and 12 collections of 4-sample GFR were also calculated. Using the 9-sample GFR as a reference value, degree of agreement was analyzed with Kendall's $\tau$ correlation coefficients, mean difference and standard deviation. Results: Although some of the 2-sample GFR showed high correlation coefficient, over or underestimation had evolved as the renal function change. The 10-120-240 min 3-sample GFR showed a high correlation coefficient (${\tau}=0.93$), minimal difference ($Mean{\pm}SD=-1.784{\pm}3.972$), and no over or underestimation as the renal function changed. The 4-sample GFR showed no better accuracy than the 3-sample GFR. Conclusions: In the wide spectrum of renal function, the 10-120-240 min 3-sample GFC could be the best choice for estimating the patients' renal function.

A Receiver for Dual-Channel CIS Interfaces (이중 채널 CIS 인터페이스를 위한 수신기 설계)

  • Shin, Hoon;Kim, Sang-Hoon;Kwon, Kee-Won;Chun, Jung-Hoon
    • Journal of the Institute of Electronics and Information Engineers
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    • v.51 no.10
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    • pp.87-95
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    • 2014
  • This paper describes a dual channel receiver design for CIS interfaces. Each channel includes CTLE(Continuous Time Linear Equalizer), sampler, deserializer and clocking circuit. The clocking circuit is composed of PLL, PI and CDR. Fast lock acquisition time, short latency and better jitter tolerance are achieved by adding OSPD(Over Sampling Phase Detector) and FSM(Finite State Machine) to PI-based CDR. The CTLE removes ISI caused by channel with -6 dB attenuation and the lock acquisition time of the CDR is below 1 baud period in frequency offset under 8000ppm. The voltage margin is 368 mV and the timing margin is 0.93 UI in eye diagram using 65 nm CMOS technology.

Evaluation of Validity Glomerular Filtration Rate Measured by Gates Method according Region of Interest (관심 영역 설정에 따른 Gates법 토리여과율의 유효성 평가)

  • Su-Young Park;Sung-Min Ahn
    • Journal of radiological science and technology
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    • v.46 no.5
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    • pp.417-425
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    • 2023
  • The glomerular filtration rate (GFR) has been the subject of much research as a key indicator for diagnosing, treating, and monitoring kidney function. The gamma camera method (Gates method) is simple and allows simultaneous acquisition of GFR and renal scintigraphy for each kidney, however its accuracy is inferior. This study aimed to investigate changes in GFR depending on how region of interest (ROI) are set up, which is one of many factors influencing accuracy. GFR was calculated by setting the ROI for each phase of the image acquisition time (Gates-1: 0~1 minutes, Gates-2: 1~3 minutes, Gates-3: 3~27 minutes), and statistical significance was verified based on probability value 0.05 through ANOVA analysis. While there was no statistically significant difference among results from Gates-1, 2, 3 (p=0.481>0.05), overall results from the Gates method tended to overestimate compared to those from the multiple blood sampling-dual exponential (MBSDE) method. When comparing averages between phases, results from Gates-2 were most similar to those from the MBSDE method. Moreover, paired t-test p-values between MBSDE method and phases were as follows Gates-1: 0.021 (p<0.05), Gates-2: 0.280 (p>0.05), and Gates-3: 0.164 (p>0.05) indicating that only Gates-1 had statistically significant differences compared with MBSDE method. Thus, setting ROI around 2~3 minutes is calculated can aid in accurately determining GFR when Gates Method.

Effect of the sampling time of high-frequency ZOH and a physical damper on stable haptic interaction (고주파 영차홀드의 샘플링 주기와 물리적 댐퍼가 안정적인 햅틱 상호작용에 미치는 영향)

  • Lee, Kyungno
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.20 no.2
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    • pp.649-654
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    • 2019
  • Stable haptic interaction with virtual environments is essential not only for the safety of the user but also for improving the immersion of the user. If the coefficient of a virtual spring is increased, the system becomes unstable. Therefore, the coefficient of the virtual spring is limited. The haptic system with the high-frequency zero-order-hold (HF-ZOH) is proposed to enhance the stability margin of a virtual spring. In this paper, the relationship among the sampling period of HF-ZOH, the coefficient of the physical damper, and the maximum stable margin of the virtual spring is analyzed. The lager the coefficient of the physical damper is, the shorter the sampling period of the HF-ZOH is, the larger the stable region of the virtual spring becomes. If the ratio N is larger than 40, the stable region of the proposed method is about three times to eight times that of the previous method, according to the coefficient of the physical damper. Hence the method enables to improve the user's realism in virtual environments.

A Design and Fabrication of Low Phase Noise Frequency Synthesizer Using Dual Loop PLL (이중루프 PLL을 이용한 IMT-2000용 저 위상잡음 주파수 합성기의 설계 및 제작)

  • Kim, Kwang-Seon;Choi, Hyun-Chul
    • The Journal of Korean Institute of Communications and Information Sciences
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    • v.27 no.2C
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    • pp.191-200
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    • 2002
  • A frequency synthesizer that can be used in IMT-2000 was designed and fabricated using dual loop PLL(Phase Locked Loop) in this paper. For improving phase noise characteristic two loops, reference loop and main loop, were divided. Phase noise was improved by transformed clamp type voltage controled oscillator and optimizing loop bandwidth in reference loop. And voltage controlled oscillator open loop gain in main loop. Fabricated the frequency synthesizer had 1.81GHz center frequency, 160MHz tuning range, 13.5dBm output power and -119.73dBc/Hz low phase noise characteristic.

Uncertainty Minimization in Quantitative Electron Spin Resonance Measurement: Considerations on Sampling Geometry and Signal Processing

  • Park, Sangeon;Shim, Jeong Hyun;Kim, Kiwoong;Jeong, Keunhong;Song, Nam Woong
    • Journal of the Korean Magnetic Resonance Society
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    • v.24 no.2
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    • pp.53-58
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    • 2020
  • Free radicals including reactive oxygen species (ROS) are important chemicals in the research area of biology, pharmaceutical, medical, and environmental science as well as human health risk assessment as they are highly involved in diverse metabolism and toxicity mechanisms through chemical reactions with various components of living bodies. Electron spin resonance (ESR) spectroscopy is a powerful tool for detecting and quantifying those radicals in biological environments. In this work we observed the ESR signal of 2,2,6,6-Tetra-methyl piperidine 1-oxyl (TEMPO) in aqueous solution at various concentrations to estimate the uncertainty factors arising from the experimental conditions and signal treatment methods. As the sample position highly influences the signal intensity, dual ESR tube geometry (consists of a detachable sample tube and a position fixed external tube) was adopted. This type of measurement geometry allowed to get the relative uncertainty of signal intensity lower than 1% when triple measurements are averaged. Linear dependence of signal intensity on the TEMPO concentration, which is required for the quantification of unknown sample, could be obtained over a concentration range of ~103 by optimizing the signal treatment method depending on the concentration range.

Decimation Chain Modeling for Dual-Band Radio Receiver and Its Operation for Continuous Packet Connectivity

  • Park, Chester Sungchung;Park, Sungkyung
    • Journal of information and communication convergence engineering
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    • v.13 no.4
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    • pp.235-240
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    • 2015
  • A decimation chain for multi-standard reconfigurable radios is presented for 900-MHz and 1,900-MHz dual-band cellular standards with a data interpolator based on the Lagrange method for adjusting the variable data rate to a fixed data rate appropriate for each standard. The two proposed configurations are analyzed and compared to provide insight into aliasing and the signal bandwidth by means of a newly introduced measure called interpolation error. The average interpolation error is reduced as the ratio of the sampling frequency to the signal BW is increased. The decimation chain and the multi-rate analog-to-digital converter are simulated to compute the interpolation error and the output signal-to-noise ratio. Further, a method to operate the above-mentioned chain under a compressed mode of operation is proposed in order to guarantee continuous packet connectivity for inter-radio-access technologies. The presented decimation chain can be applied to LTE, WCDMA, GSM multi-mode multi-band digital front-end which will ultimately lead to the software-defined radio.

The Three Directional Separable Processing Method for Double-Density Wavelet Transformation Improvement (이중 밀도 웨이브렛 변환의 성능 향상을 위한 3방향 분리 처리 기법)

  • Shin, Jong Hong
    • Journal of Korea Society of Digital Industry and Information Management
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    • v.8 no.2
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    • pp.131-143
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    • 2012
  • This paper introduces the double-density discrete wavelet transform using 3 direction separable processing method, which is a discrete wavelet transform that combines the double-density discrete wavelet transform and quincunx sampling method, each of which has its own characteristics and advantages. The double-density discrete wavelet transform is nearly shift-invariant. But there is room for improvement because not all of the wavelets are directional. That is, although the double-density DWT utilizes more wavelets, some lack a dominant spatial orientation, which prevents them from being able to isolate those directions. The dual-tree discrete wavelet transform has a more computationally efficient approach to shift invariance. Also, the dual-tree discrete wavelet transform gives much better directional selectivity when filtering multidimensional signals. But this transformation has more cost complexity Because it needs eight digital filters. Therefor, we need to hybrid transform which has the more directional selection and the lower cost complexity. A solution to this problem is a the double-density discrete wavelet transform using 3 direction separable processing method. The proposed wavelet transformation services good performance in image and video processing fields.

Study on the Characteristics of Fashion Leaders in College Clubs' Fashion Networks

  • Yun, So Jung;Jung, Hye In;Choo, Ho Jung;Jeong, So Won
    • International Journal of Costume and Fashion
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    • v.14 no.1
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    • pp.1-15
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    • 2014
  • Fashion leadership is divided into visual influence, linguistic influence, and dual leadership. We refer to people exercising such influential power as fashion innovators, fashion opinion leaders, and fashion double leaders, respectively. Scholars and marketers have raised continuous questions on this issue: who are these fashion leaders and what characteristics do they have? In this study, social network analysis is applied to grasp the existence of three types of fashion leaders in college clubs, examine their positions in fashion process networks and investigate their individual and social characteristics. For this study, three college clubs were recruited through convenience sampling and surveyed online. Peer nomination questions for structuring fashion process networks and self-evaluation questions for measuring personal characteristics are included. Two fashion networks, an opinion leadership network and an innovativeness network, embrace four to six leaders and illustrate similar structure patterns in the three groups, which indicates that dual leaders enjoyed the lion's share in college clubs. The number of fashion innovators tends to be fewer compared to that of fashion opinion leaders, and we infer that peer relationship appears to intervene with fashion opinion leadership. Other personal characteristics supporting results from previous studies are also confirmed in this study.

The Effect of Personalized Product Recommendation Service of Online Fashion Shopping Mall on Service Use Behaviors through Cognitive Attitude and Emotional Attachment (온라인 패션쇼핑몰의 개인 상품 추천서비스가 인지적 태도와 감정적 애착을 통해 서비스 사용행동에 미치는 영향)

  • Choi, Mi Young
    • Fashion & Textile Research Journal
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    • v.23 no.5
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    • pp.586-597
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    • 2021
  • Personalized product recommendation service is receiving attention as a new marketing strategy while supporting consumer information search and purchasing decisions. This study attempted to verify the effect of self-reference on service use behavior through the dual path of cognitive attitude and emotional attachment. Using convenience sampling, an online survey was conducted with 324 women who were in their 20s and 30s. After collecting and compiling the survey data, the reliability and validity of variables constituting the conceptual research model were verified through confirmatory factor analysis using AMOS 22.0. Next, the significance of sequentially mediated pathways was verified using Process 3.5 Model 80. The results showed that self-referencing not only significantly affects service use intention by simply mediating cognitive attitudes but also sequentially mediates cognitive attitudes and additional information search. Furthermore, self-referencing was significant as an indirect path to service use intention by mediating additional information search. However, in the path mediated by emotional attachment, self-referencing was considered as a simple mediated path leading to service usage intention. These results indicate a dual path in the psychological mechanism, through cognitive and emotional evaluation, that prompts consumer behavioral responses to the personalized product information provided in the shopping process.