• Title/Summary/Keyword: drop system

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WETTABILITY AND DRUG DELIVERY OF FUNCTIONALLY GRADED NANO-MICRO POROUS TITANIUM SURFACE

  • Yun, Kwi-Dug;Vang, Mong-Sook;Yang, Hong-So;Park, Sang-Won;Park, Ha-Ok;Lim, Hyun-Pil
    • The Journal of Korean Academy of Prosthodontics
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    • v.46 no.3
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    • pp.307-319
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    • 2008
  • STATEMENT OF PROBLEM: It is known that an anodic oxidation technique, one of the methods for the implant surface treatment, remarkably increased surface area, enhanced wettability and accelerated the initial bone healing. Purpose: This study was performed to evaluate the wettability of anodized titanium surface which has a nanotubular structure, to assess osseointegration after the placement of implant with nano-size tubes on tibia of rats and to analyze quantitatively transferable rhBMP-2 on each surface. MATERIAL AND METHOD: Four different kinds of surface-treated titanium discs (polished (machined surface) group, micro (blasting surface) group, nano (anodizedmachined surface) group, and nano-micro (anodized-blasting surface) group) were fabricated (n=10). Three different media were chosen to measure the surface contact angles; distilled water, plasma and rhBMP-2 solution. After a single drop (0.025 $m{\ell}$) of solution, the picture was taken with the image camera, and contact angle was measured by using image analysis system. For the test of osseointegration, 2 kinds of anodized surface (anodized-machined surface, anodized-blasting surface) implants having 2.0 mm in diameter and 5.0 mm in length inserted into the tibia of Wistar rats. After 3 weeks, tibia were harvested and the specimens were stained with hematoxylin and eosin for histological analysis. To test the possibility of drug delivery, after soaking sample groups in the concentration of 250 ng/$m{\ell}$l of rhBMP-2 for 48 hours, the excess solution of rhBMP-2 were removed. After that, they were lyophilized for 24 hours, and then the rhBMP-2 on the surface of titanium was resolved for 72 hours in PBS. All the extracted solution was analyzed by ELISA. One-way analysis of variance (ANOVA) was performed on the data. RESULTS: The wettability is improved by anodic oxidation. The best wettability was shown on the nano-micro group, and it was followed by nano group, micro group, and polished group. In the histological findings, all implants showed good healing and the new bone formation were observed along the implant surface. After 3 days, nano-micro group delivered the most amount of rhBMP-2, followed by nano group, micro group, and polished group. CONCLUSION: It indicated that anodic oxidation on blasting surface produce functionally graded nano-micro porous structure and enhance hydrophilicity of the surface and osseointegration. The findings suggest that the nano-micro porous structure could be a useful carrier of osteogenic molecules like rhBMP-2.

Actual Utilization and Thermal Environment of Greenhouses According to Several Cooling Methods during Summer Season (하절기 온실의 활용실태 및 몇 가지 고온극복 방법별 열환경 분석)

  • 남상운
    • Journal of Bio-Environment Control
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    • v.9 no.1
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    • pp.1-10
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    • 2000
  • This study was performed to find an efficient method to overcome extremely high temperature in greenhouses during summer season. The actual utilization of greenhouses during hot summer season showed that about 21.6% of the investigated greenhouse farms were in fallow state, and most of greenhouse farms were cultivated under the very inferior environment. Thermal environment of greenhouses according to the evaporative cooling method and several assistant cooling methods such as ventilation, shading screen, roof sprinkling were examined. As the each assistant cooling method was used, about 74.8%, 25.9%, and 58.2% of temperatures measured at intervals of ten minutes between ten and seventeen o'clock were above 35$^{\circ}C$. When shading screen and evaporative cooling system were operated, most greenhouse air temperatures were maintained below 35$^{\circ}C$, and showed a drop of 3.8~4.2$^{\circ}C$ as compared with naturally ventilated greenhouse.

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An Energy Balancing Low Power Routing Method for Sensor Network with Fixed Data Acquisition Nodes (고정식 정보획득 노드로 구성된 센서 네트워크에 적용 가능한 에너지 밸런싱 저전력 라우팅 기법)

  • Jeong Gye-Gab;Kim Hwang-Gi;Lee Nam-Il;Kim Jun-Nyun
    • Journal of the Institute of Electronics Engineers of Korea TC
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    • v.41 no.6 s.324
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    • pp.59-68
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    • 2004
  • Thanks to the development of microelectromechanical systems(MEMS), wireless communication technology and microsensor technology, it was Possible to manufacture a very small and low costdata acquisition node with sensing function, processing function, wireless communication function and battery. Thus sensor networks begin to be prevailed. The sensor network is a spontaneous system which sets up automatically routing paths and transmits asignificant data to the destination. Sensor nodes requires low-power operation because most of them use a battery as operating power. Sensor nodes transmit a sensing data to the destination. Moreover, they play a router. In fact, because the later consumes more energy than the former, the low-power routing is very important. Sensor networks don't have a routing standard unlike general wireless Ad-hoc networks. So This paper proposes a low-power routing method for anting to sensor networks. It is based on AODV and adapts a method to drop probably RREQ depending on remaining power. We examined it through simulations. From simulation results, we could confirm to reduce power consumption about $10-20\%$ and distribute equally power consumption among nodes.

The Development of HACCP-Based Standardized Recipe and the Quality Assessment of Cook/Chilled Soy Sauce Glazed Mackerel (쿡췰(Cook/Chill)시스템을 이용한 고등어조림의 HACCP 레시피 개발 및 생산과정의 품질평가)

  • Kwak, Tong-Kyung;Lee, Kyung-Eun;Park, Hye-Won;Ryu, Kyung;Hong, Wan-Soo;Choi, Eun-Jung;Jang, Hye-Ja;Kim, Sung-Hee
    • Korean journal of food and cookery science
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    • v.13 no.5
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    • pp.592-601
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    • 1997
  • The purposes of this study were to develop Hazard Analysis Critical Control Point-based standardized recipe applicable to cook/chilled soy sauceglazed mackerel and to evaluate the qualities related to the product flow of this item. After conducting experimental cooking, preliminary test, and analysis of recipes, critical control points were identified, control methods were determined, and HACCP-based recipe was standardized. At each critical control point, time-temperature profile was recorded and microbiological analysis (total aerobic plate counts, psychrotrophic plate count, coliform, and fecal coliform count), chemical analysis (pH, acid value and volatile based nitrogen (VBN)) and sensory evaluation of the item were done. Time-temperature data showed that the time the menu item had passed through temperature danger zone (5∼60$^{\circ}C$) during all phases was 60 min. At rapid cooling, but after cooling at room temperature, the temperature of this menu item did not drop below the ambient temperature. The results of microbiological test were negative throughout all phases following cooking and the results of chemical analysis did not change significantly in terms of storage periods except for VBN which increased on 7th day significantly(p<0.05). After steam/convection oven reheating and microwave oven reheating, the sensory score of the only appearance decreased significantly related to the storage time of overall quality profiles. But significant differences were not detected according to two reheating methods. In conclusion, this HACCP-based recipe was considered as an effective tool for assuring microbial as well as sensory quality of this cook/chilled item.

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Study on the Applicability of Reflection Method using Ultrasonic Sweep Source for the Inspection of Tunnel Lining Structure - Physical Modeling Approach - (터널 지보구조 진단을 위한 초음파 스윕 발생원의 반사법 응용 가능성 연구 - 모형실험을 중심으로 -)

  • 김중열;김유성;신용석;현혜자
    • Proceedings of the Korean Geotechical Society Conference
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    • 2001.03a
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    • pp.167-174
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    • 2001
  • Reflection method using ultrasonic source has been attempted to obtain the information about tunnel lining structures composed of lining, shotcrete, water barrier and voids at the back of lining. In this work, two different types of sources, i.e. single-pulse source and sweep source, can be used. Single-pulse source with short time duration has the frequency content whose amplitudes tend to be concentrated around the dominant frequency, whereas sweep source with long time duration denotes a flat distribution of relatively larger amplitude over a broad frequency band, although the peak to peak amplitude of single-pulse source wavelet is equivalent to that of sweep source one. In traditional seismic application, a single-pulse source(weight drop, dynamite) is typically used. However, to investigate the fine structure, as it is the case in the tunnel lining structure, the sweep wavelet can be also a desirable source waveform primarily due to the higher energy over a broad frequency band. For the investigation purposes of sweep source, a physical modeling is a useful tool, especially to study problems of wave propagation in the fine layered media. The main purpose of this work was using a physical modeling technique to explore the applicability of sweep source to the delineation of inner layer boundaries. To this end, a two-dimensional physical model analogous to the lining structure was built and a special ultrasonic sweep source was devised. The measurements were carried out in the sweep frequency range 10 ∼ 60 KHz, as peformed in the regular reflection survey(e.g. roll-along technique). The measured data were further rearranged with a proper software (cross-correlation). The resulting seismograms(raw data) showed quitely similar features to those from a single-pulse source, in which high frequency content of reflection events could be considerably emphasized, as expected. The data were further processed by using a regular data processing system "FOCUS" and the results(stack section) were well associated with the known model structure. In this context, it is worthy to note that in view of measuring condition the sweep source would be applied to benefit the penetration of high frequency energy into the media and to enhance the resolution of reflection events.

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The Development and Application of Standard Diagnostic Table for Astringent Persimmon Management (떫은감 경영 표준진단표의 개발 및 현지 적용)

  • Jeon, Jun-Heon;Lee, Seong-Youn;Lee, Jung-Min;Ji, Dong-Hyun;Oh, Chan-Jin
    • Journal of Korean Society of Forest Science
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    • v.104 no.3
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    • pp.488-494
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    • 2015
  • This study aims to develop and apply a standard management self-diagnostic table for forestry households to better manage their astringent persimmon production. The diagnostic table consisted of 3 categories (general status of a forestry household, management performance indicators, level of management) and 18 subcategories. The current management status across 241 households was surveyed among 10 chief astringent persimmon producing municipalities. Scores from the 18 subcategories were aggregated for a total score to evaluate and compare different levels of management. The respondents scored an overall average of 57.4, 62% of which were placed between 40 and 60. Upon close examination Chungcheongnam-do scored a very low score in the 'management system-tree height' subcategory with respect to the average score potentially because of the large population of aged trees in the region. The national average in the 'production skills-time of fruit load adjustment' subcategory was only 1.96 because unlike sweet persimmons astringent persimmons adjust their own load by inducing physiological fruit drop. The national average in the 'management/sales skills-material purchase' subcategory was 2.01; over 60% of the respondents indicated a preference for independent selection and purchase for most materials. The households preferring a group purchase tended to utilize the regional co-op.

Evaluation of Digital PCR as a Technique for Monitoring Acute Rejection in Kidney Transplantation

  • Lee, Hyeseon;Park, Young-Mi;We, Yu-Mee;Han, Duck Jong;Seo, Jung-Woo;Moon, Haena;Lee, Yu-Ho;Kim, Yang-Gyun;Moon, Ju-Young;Lee, Sang-Ho;Lee, Jong-Keuk
    • Genomics & Informatics
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    • v.15 no.1
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    • pp.2-10
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    • 2017
  • Early detection and proper management of kidney rejection are crucial for the long-term health of a transplant recipient. Recipients are normally monitored by serum creatinine measurement and sometimes with graft biopsies. Donor-derived cell-free deoxyribonucleic acid (cfDNA) in the recipient's plasma and/or urine may be a better indicator of acute rejection. We evaluated digital PCR (dPCR) as a system for monitoring graft status using single nucleotide polymorphism (SNP)-based detection of donor DNA in plasma or urine. We compared the detection abilities of the QX200, RainDrop, and QuantStudio 3D dPCR systems. The QX200 was the most accurate and sensitive. Plasma and/or urine samples were isolated from 34 kidney recipients at multiple time points after transplantation, and analyzed by dPCR using the QX200. We found that donor DNA was almost undetectable in plasma DNA samples, whereas a high percentage of donor DNA was measured in urine DNA samples, indicating that urine is a good source of cfDNA for patient monitoring. We found that at least 24% of the highly polymorphic SNPs used to identify individuals could also identify donor cfDNA in transplant patient samples. Our results further showed that autosomal, sex-specific, and mitochondrial SNPs were suitable markers for identifying donor cfDNA. Finally, we found that donor-derived cfDNA measurement by dPCR was not sufficient to predict a patient's clinical condition. Our results indicate that donor-derived cfDNA is not an accurate predictor of kidney status in kidney transplant patients.

Changes of Nursing Activities on Patients with DNR Orders (DNR 결정 환자에 대한 간호사의 간호활동 변화)

  • Lee, Ji Yun;Jang, Jae In
    • Journal of Hospice and Palliative Care
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    • v.20 no.1
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    • pp.46-57
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    • 2017
  • Purpose: The purpose of this study is to identify the changes to nursing activities of nurses on patients with DNR (Do-Not-Resuscitate) order and factors associated to the changes. Methods: Data were collected using a structured questionnaire for 173 nurses at general hospitals. Logistic regression analysis was performed on the data using SAS 9.4. Results: With 39 nursing activities, an average of 60.4 (34.9%) nurses reported an increase in the activities, 102.4 (59.2%) no change and 10.1 (5.9%) a drop. The activity increase was the greatest in the social area, and the physical area was where the activities decreased the most. The activity increase was associated knowledge competency (9 items), attitudes (2 items), practical competency (4 items) and work load (14 items were). Conclusion: To offer systematical care for DNR patients, it is necessary to expand nurses' knowledge through end-of-life education and adjust their workload and provide a support system at the department level.

System design of Overseas Journal Original Text Service for interlibrary loan (상호대차를 위한 해외저널 원문서비스 시스템 설계)

  • 이계준;김상국;이명선
    • Proceedings of the Korea Society for Industrial Systems Conference
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    • 2000.11a
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    • pp.493-503
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    • 2000
  • 인터넷은 "정보의 바다"라는 말처럼 날마다 방대한 양의 데이터가 쏟아져 나오고 있으며, 이런 방대한 데이터 속에서 정보를 찾기란 쉽지 않다. 그러나 인터넷 사용자들은 정확한 정보를 신속하게 언제 어디서나 획득할 수 있기를 희망한다. 현재 정보의 창고인 도서관은 더 이상의 Paper 정보가 아닌 Digital 정보로의 변화가 필요하며 각 분야에서 많은 연구가 이루어지고 있다. 연구개발정보센터(KORDIC)에서는 과학기술지역인프라 구축사업을 통해서 광주ㆍ전남권역을 시범 권역으로 선정하여 13개 대학의 도서관, 산업단지, 연구소(KORDIC)를 하나로 묶는 즉, 산ㆍ학ㆍ연이 하나가 되어 상호대차 원문 서비스를 할 수 있도록 기반을 구축하는데 목적이 두고있다. 본 시스템은 상호대차 원문 서비스를 위해 대학 간 분담수서를 통해서 분담된 도서를 원문서비스 하는 상호 협력 체제를 구축하는데 필요한 시스템이며 사용자들은 해외 저널 원문을 신청하게되고, 서비스 담당자는 신청된 해외저널원문을 Digital화해서 사용자에게 보내주는 체제를 구축하기 위해 열악한 대학에는 시스템과 통신 인프라를 지원하여 상호대차원문서비스가 가능하게 하는 것을 전제로 하고 있다. 분담수서를 통해 서비스하게 될 해외저널에 대해서는 각 대학에서 책임감을 가지고 서비스를 해야하므로 서비스의 질과 업무의 자립도를 높일 수 있으며 상호대차를 통해 산ㆍ학ㆍ연이 하나처럼 연계가 된다. 또한 해외 학술 저널 DB를 공동으로 구축하여 국내 지역별 대학소장 해외 학술 전문자료를 데이터베이스화, 전문정보망을 구축 회원기관 간 정보교류의 활성화, 대학 소장 해외 학술 전문자료의 정보 표준화 효과를 창출할 수 있으며, 분담수서를 통해 얻어지는 예산 절감으로 새로운 분야에 재투자한다면 정보의 질적, 양적 향상을 도모하게 될 것이다.것으로 나타났다.본 규격은 키, 총장, 어깨길이, 등길이, 머리길이, 머리둘레, 진동둘레, 목둘레, 가슴둘레, 허리둘레, 배둘레, 엉덩이둘레, 앞품, 뒤품, drop치를 포함하고 있고, 각 규격에서 호칭간 치수 간격도 함께 제시하고 있다. 본 연구 결과에서 보듯, 현행 8규격의 무진복의 각 호칭간 적정 허용범위를 고려해 합리적인 치수체계를 정립한다면 치수에 대한 적합도가 상당히 증가할 뿐 아니라 생산비용도 상당히 감축할 것으로 생각된다.나타났다. 4) 호감적 서비스능력 차원에서 세 독립변수간에 유의한 3원 상호작용이 존재하는 것으로 나타나( $F_{2,228}$=15.62, P<.001) 20대에 적합한 의복 착용시( $F_{2,228}$=3.98, P<.05)와 60대에 적합한 의복 착용시( $F_{2,228}$=16.55, P<.001) 점포유형과 격식차림간에는 유의한 상호작용이 존재하는 것으로 나타났다. 5) 호감을 구성하는 세 요인들이 구매의도에 미치는 영향을 조사한 결과 호감적 인상차원은 29%(P<.001), 호감적 서비스능력차원은 6%(P<.001)의 구매의도를 설명해 주는 것으로 나타났다. 본 연구결과 노년 소비자에게 호감을 주는 판매원의 외모는 구매의도에 영향을 주어 실버의류산업의 이익증대와 밀접한 연관을 갖는 서비스품질의 중요한 요인으로 밝혀졌다.중요한 요인으로 밝혀졌다.로운 단백질 EPSPS가 다른 여러 식물에 이미 존재하고 있는 단백질로서 우리가 이미 이러한 식품을 섭취할 때 이 단백질도 같이 섭취해오고 있었다는 점, 둘째. 이 단백질이 소화액 분해 실험에서 짧은 시간내에 분해가 되었다는 점, 셋째. 재조합 된 콩과 자연 콩이 성분 분석에서 차이를 나타내지 않았다는 점, 네 번째. 쥐를 통한 다양섭취

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Pre-concentration of Apple Juice with Different Reverse Osmosis Membranes (역삼투막을 이용한 사과쥬스의 예비농축)

  • Kim, Kil-Hwan;Park, Hyun-Jin;Kim, Dong-Man
    • Korean Journal of Food Science and Technology
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    • v.20 no.3
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    • pp.419-425
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    • 1988
  • The clarified apple juice was pre-concentrated by reverse osmosis system as a trial for reduction of heat treating time and quality drop in concentration of the juice. The permeate fluxes through CA 865 and CA 960 membranes were higher than those of HR 95 and HR 98 membranes even at the low operating pressure. In the concentration limit depended on the membranes used, HR membranes operated at 60 bar showed $29.0^{\circ}$Brix, and the time required to reach the limit was 86 min for HR 95 and 71 min for HR 98. In cases of CA membranes run at 30 bar, the juice concentration was linearly increased without the limit, and longer time to reach the same concentration was required in comparison with HR membranes. As the juice concentration was increased, the loss of soluble solids was increased, and the average contents of soluble solids in the permeate passed through HR 95, HR 98, CA 865 and CA 960 were 1.3, 0.5, 7.5 and $2.3^{\circ}$ Brix, respectively, in the juice concentration range of 20.0 -$25.0^{\circ}$ Brix. The lower amounts of sugars, total acid and flavor volatiles were involved in the permeate through HR membranes, especially HR 98 than in the permeate through CA membranes.

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