• 대한치과교정학회지
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• 제23권4호
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• pp.485-492
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• 1993

Multiloop Edgewise Archwire(MEAW) is effective in relief the Curve of Spee in mandibular arch but up Sl down orthodontic elastics must be used with it. The purpose of this study was to analyse the effect of orthodontic elastics, like as up & down elastics, Class II elastics, and Class III elastics, and the effect of L loop in Multioop Edgewise Archwire. 1. Intrusive force of MEAW in anterior teeth was reduced and uprighting force in premolars was increased by up & down elastics. 2. Uprighting force was significintly increased with Class III elastics in multiple L loop arch wire. 3. The force of Class II elastics made molars tip mesially and Curve of Spee deep.

• Bulletin of the Korean Chemical Society
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• 제30권12호
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• pp.2890-2894
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• 2009

The larch-fruit-like acetylferrocene micro-nanomaterials and beltlike acetylferrocene micro-nanomaterials have been cross-correspondingly prepared in bidirection by the top-down and bottom-up approach, respectively, and characterized by scanning electron microscope, transmission electron microscope and X-ray diffractometer. UV-Vis absorption spectra show that the redshift was found in the acetylferrocene micro-nanomaterials compared to that in solution. The formation mechanism of the acetylferrocene micro-nanomaterials is also proposed. This work provides a new strategy for the material synthesis and preparation and may realize the reuse of organometallic materials.

• 제어로봇시스템학회:학술대회논문집
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• 제어로봇시스템학회 2001년도 ICCAS
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• pp.69.6-69
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• 2001

The SSPA makes the power level of EIRP up to 16W, and compensates for temperature to the SSPA´s maximum stability. The up and the down converters are dually conversed like as individual synthesizers for selecting of independent transmit-receive transponder. The function of the up-converter is to convert the 70MHz IF signal modulated in the indoor unit modem into a 14.0 ∼ 14.5 GHz Ku-band up-link signal to be sent to the antenna. The down-converter converts the 12.25 ∼ 12.75 GHz Ku-band down-link signal or a trouble malfunction of SSPA may be a fatal factor to operation of the whole satellite communication network. Therefore, this study developed the remote monitoring and control program to monitor the SSPA´s status before the problem occurs for stable operation of the system. This software ...

• IMMUNE NETWORK
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• 제11권4호
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• pp.223-226
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• 2011

Although exercise-induced growth factors such as Insulin-like growth factor-I (IGF-I) are known to affect various aspects of physiology in skeletal muscle cells, the molecular mechanism by which IGF-I modulates anti-inflammatory effects in these cells is presently unknown. Here, we showed that IGF-I stimulation suppresses the expression of toll-like receptor 4 (TLR4), a key innate immune receptor. A pharmacological inhibitor study further showed that PI3K/Akt signaling pathway is required for IGF-I-mediated negative regulation of TLR4 expression. Furthermore, IGF-I treatment reduced the expression of various NF-${\kappa}B$-target genes such as TNF-${\alpha}$ and IL-6. Taken together, these findings indicate that the anti-inflammatory effect of exercise may be due, at least in part, to IGF-I-induced suppression of TLR4 and subsequent downregulation of the TLR4-dependent inflammatory signaling pathway.

• 조명전기설비학회논문지
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• 제25권12호
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• pp.11-20
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• 2011

PSALI is referred to the supplementary lighting for the interior lighting under the daily lighting situation, and pursuant to the pertinent regulations in energy savings design standard and others in recent architecture works, the importance thereof has been increasing gradually coupled with the energy performance index (EPI), energy savings plan and the like as well as expansion of submittal and implementation policies. However, this type of PSALI studies indeed have a number of limitations since it has surrounding environmental conditions in direction, season, region, climate, time, opening rate, window area ratio, actual index, reflection rate of finishing materials and others in the architecture work as well as frequent changes in interior lighting environment for variables in daily light volume flowing into the interior, and others. Therefore, this study has analyzed existing advance research cases to produce the actual-sized model and scaled-down model, and installed the artificial lighting of LED light source possible to reproduce with same capability on both models. As a result of comparison and analysis of the artificial lighting with the key light, it has certain level of error rate from the scaled down lighting device in certain rate and actual model butit was noticeably significant within specific scope.

• Journal of Microbiology and Biotechnology
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• 제28권11호
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• pp.1908-1915
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• 2018

Upon viral infection, the host cell recognizes the invasion through a number of pattern recognition receptors. Melanoma differentiation associated gene 5 (MDA5) and retinoic acid-inducible gene-I (RIG-I) recognize RNA molecules derived from invading viruses, activating down-stream signaling cascades, culminating in the induction of the type I interferon. On the other hand, viruses have evolved to evade type I interferon-mediated inhibition. Hepatitis E virus has been shown to encode a few antagonists of type I interferon and it is not surprising that viruses encode multiple mechanisms of viral evasion. In the present study, we demonstrated that HEV PCP strongly down-regulates MDA5-mediated activation of interferon ${\beta}$ induction in a dose-dependent manner. Interestingly, MDA5 protein expression was almost completely abolished. In addition, polyinosinic polycytidylic acid (poly(I:C))- and Sendai virus-mediated activation of type I interferon responses were similarly abrogated in the presence of HEV PCP. Furthermore, HEV PCP down-regulates several molecules that play critical roles in the induction of type I IFN expression. Taken together, these data collectively suggest that HEV-encoded PCP is a strong antagonist of type I interferon.

• 대한치과교정학회지
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• 제10권1호
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• pp.37-43
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• 1980

This study was undertaken to assess the effects of demethylchlortetracycline on bone growth of mandibular symphyseal region in rats. Demethylchlortetracycline at 30mg/kg body weight, respectively, were daily administered by mouth to the sewen female rats from 10th day of pregnancy to 13th day. Thirty six new-born rats from these experimental animals were used for histological examination at 1, 5, 10, 15, 20, 25 and 30 days. All these new-born rats were killed by an overdose of ether. Mandibular bodies were removed and fixed in $10\%$ neutral formalin,. Carney and aceton. Specimens were embedded, sectioned and stained with H-E, Van Gieson, PAS and prepared for alkaline phosphatase. The results were as follows; 1. Until erupting of incisors, hyaline cartilage was located in relatively large symphyseal space, but bone trabeculae of ossifying area at incisal side were arranged irregularly in experimental group. 2. During this period, PAS reaction was moderately positive, but alkaline phosphatase reaction was slightly positive. 3. By erupting or incisors, symphyseal space appeared narrower like control group, but alkaline phosphatase reaction tended to slow down. 4. By erupting of molars, symphyseal space appeared muck narrower, and cartilane plate was reduced and aealed off like control group. Alkaline phosphatase reaction tended to slow down severely.

• 복식
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• 제58권7호
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• pp.151-163
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• 2008

This study was undertaken to design Ginyeo's character and costume in the early-middle Goryeo Dynasty which had a few relics, and to make practical cultural contents. The famous Goryeo Ginyeos who had real names are costume characters. Goryeo women dressed in delicate white ramie jarket in "Goryeo-dokyung", and the shape of Jacket can be two kinds: long-wide jacket enough to tie a belt, and long caftan cover the knee. Goryeo women enjoyed wide yellow skirt, but Ginyeo in "Dongguk-isanggutjip" put on pink, flower, pomegranate, red skirt for high class ladies. In the case of Mong-su(a head cloth with black gauze train), it is thought that Ginyeo fold up train like lower class or just hang down like ordinary women, because of their status. As underwear, a ramie jacket and wide underpants were set up. It is needed that many Golden bells and jade trinkets must be attached to Goryeo Ginyeo's waist to stress their characteristics. Ginyeo's hair style can be designed so that a bunch of right hair was dropped down and the rest hair was rolled on reft shoulder. To design a Ginyeo's costume chatacter of the early-middle Goryeo, the richness of wide skirt, delicacy of white ramie, a great deal of trinkets must be emphasized correctly as a characteristic of Goryeo women's costume in that period.

• 한국환경독성학회:학술대회논문집
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• 한국환경독성학회 2003년도 추계국제학술대회
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• pp.176-176
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• 2003

Methylmercury is known to have devastating effects on the mammalian nervous system. When human neuroblastoma SH-SY5Y cells were treated with methylmercury at sublethal concentrations (6.25 uM), up-regulated genes (39) ＆ down-regulated genes (19) were identified by human 8k cDNA microarray. These genes are related with microtubule process, signal transduction pathway and cell death (apoptosis), Apoptosis-associated genes, HSP70, CDK inhibitor 1, FOS-like antigen were up-regulated and microtubule related genes like villin and dynein down-regultaed. To confirm the presence of apoptosis in cultured SH-SY5Y cells treated 6.25 and 1 uM methylmercury, we applied Annexin V-FITC assay followed by flow cytometric measurements after 6 and 24h. Studies on transcriptional and molecular effect by methylmercury may provide an insight into the neurotoxic effects of methylmercury in human neuronal cells and a possibility to develop more efficient and exact monitoring system of heavy metals as ubiquitous environmental pollutants.

• Bulletin of the Korean Chemical Society
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• 제25권12호
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• pp.1863-1868
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• 2004

Kringle 5 (K5), located outside of angiostain (K1-4) in human plasminogen, displays more potent antiangiogenic activity on endothelial cell proliferation than angiostatin itself. Using a yeast two-hybrid system in vivo, we have recently identified Rgl2 (guanine nucleotide dissociation stimulator (RalGDS)-like factor 2) as a binding protein of human K5. In order to confirm in vitro protein interaction between K5 and Rgl2, we developed bacterial recombinant expression systems for them. K5 and Rgl2 proteins were expressed in high yields and purified into pure forms with His tags and GST fusion, respectively. GST-pull down experiments clearly demonstrated that K5 interacts specifically with Rgl2 in vitro. These results indicate that Rgl2 functions as a receptor protein for K5 in vitro as well as in vivo, leading to anti-angiogenesis through regulating Ras signaling pathways.