• The Korean Journal of Pain
• /
• v.1 no.1
• /
• pp.80-86
• /
• 1988

Caudal buprenorphine was investigated as a postoperative analgesic in a randominzed double blind study of 45 patients after abdominal surgery. At the end of surgery, patients were given 0.2 mg of caudal buprenorphine in 20 ml saline(n=30, experimental group) or no injection(n=15, control group). Pain relief was evaluated by the subsequent need for systemic analgesics(pethidine). Arterial blood gas and micturition disturbance were evaluated. In the buprenophine group, use of systemic analgesics was significantly reduced for the first 24 hours postoperatively. Arterial blond gas study values 2 hollers after buprenorphine administration were within normal range. 8 patients of the buprenorphine group developed urinary retention requiring temporary Nelaton catheterization of the bladder. Caudal buprenorphine for postoperative pain control was a good alternate method of postoperative pain management.

• Proceedings of the Korean Society for Emotion and Sensibility Conference
• /
• 2009.05a
• /
• pp.217-218
• /
• 2009

총 19 명 (male=9, female=10)을 대상으로 자기 보고식 질문지를 일주일 간격으로 2 회 수행한 후 double blind 방식과 실험 목적/프로토콜을 피검자에게 알려주지 않은 상태로 EEG 검사를 수행하여 행동활성화체계/행동억제체계(BAS/BIS)를 분석하였다. 안정기를 거친 후 갑자기 불유쾌한 청각적 자극(1Hz, 110dB, 15초간)을 2 회 실시하여 BAS/BIS 수치의 변화를 분석하였다. 분노활성화 음성자극에 대한 BAS/BIS 성향 대상자들의 반응을 분석하여 그 변화추이를 살펴보고자 함이 본 연구의 목적이다.

• Food Science and Biotechnology
• /
• v.18 no.2
• /
• pp.432-435
• /
• 2009

The preventive effect of chewing gum containing maltitol, xylitol, gum base, and sugar on remineralization were investigated. The clinical study consisted of 8 weeks' randomized, double blind, controlled, cross-over clinical trials including 24 healthy adults had chew gum. After each test week, remineralization effect was evaluated by measuring microhardness and scanning electron microscopy (SEM). Microhardness of experimental chewing gum containing maltitol or xylitol was significantly higher than that of sugar gum (p<0.005). Images of SEM showed the remineralization effect of gum containing gum base, maltitol, or xylitol compared with sugar gum. Maltitol and xylitol gums were more effective in remineralization than sugar gum. It was concluded that maltitol and xylitol can be used as sugar substitute to prevent dental caries.

• Journal of Periodontal and Implant Science
• /
• v.24 no.1
• /
• pp.196-204
• /
• 1994

The purpose of this clinical trial was to study the effectiveness of 5% potassium nitrate dentifrice as a daily home treatment of dentinal hypersensitivity. Thirty subjects with dentinal hypersensitivity were included in a 4-week, double-blind, parallel, comparative study. Stimuli used included mechanical, cold water and compressed air blasts. A subjective assessment of the degree of hypersensitivity for each stimulus was recorded. The results indicated that 5% potassium nitrate dentifrice, in comparision with a conventional fluoride dentifrice, reduced dentinal hypersensitivity to a significant degree. The therapeutic response to potassium nitrate was apparent within 2 weeks and increased continuously for the length of the study period. We conclude that 5% potassium nitrate dentifrice is an effective agent for the daily home treatment of dentinal hypersensitivity.

• Sleep Medicine and Psychophysiology
• /
• v.4 no.2
• /
• pp.181-190
• /
• 1997

Zolpidem is a relatively new, short-acting, rapid onset, and nonbenzodiazepine hypnotics. Zolpidem selectively binds to the central benzodiazepine 1 (BZI) receptor subtype. The present study was designed to compare the hypnotic effects of zolpidem (10 mg), triazolam (0.25 mg), and placebo in 22 schizophrenic inpatients. Zolpidem, triazolam, and placebo were administered orally in a randomized, double-blind design. Compared with placebo, zolpidem and triazolam significantly decreased sleep latency (p<0.05), increased total sleep time (p<0.05), and increased improvement of satisfaction of sleep (p<0.05). Zolpidem decreased the number of awakenings significantly in comparison with placebo (p<0.05), but triazolam did not. In addition, both drugs were well tolerated and did not produce severe side effects. These results suggest that zolpidem is effective for transient insomnia of schizophrenic inpatients and zolpidem is superior to triazolam in hypnotic effect.

• Proceedings of the Ginseng society Conference
• /
• 1988.08a
• /
• pp.108-114
• /
• 1988

One of the major effects of Panax ginseng the best known traditional medicine in the Far East. is the enhancement of host resistance against infections. which could depend on an influence from the immune system. The studies presented have been carried out with extracts from Korean ginseng roots which were examined for immunological activity in vitro and in vivo. The results obtained in a double-blind clinical study with humans confirmed results obtained in vitro with human granulocytes and in vivo with mice. The ginseng extracts showed a significant stimulatory action on the immune response.

• Journal of Chest Surgery
• /
• v.18 no.4
• /
• pp.740-745
• /
• 1985

A retrospective double blind study comparing 7 day with 2 day regimen of antibiotic prophylaxis was conducted among 200 patients undergoing open heart surgery. No case of endocarditis and wound infection occurred. Pneumonia developed in 5 cases of the 7 day and 1 case of the 2 day group. Urinary tract infection without clinical significance developed in 1 case of the 7 day and 3 cases of the 2 day group. Bacteremia developed in 2 cases of the 7 day and 1 case of the 2 day group. We concluded as follows: l. Administration of antibiotics for 2 days appears to be without substantial risk of infection comparing long term 7 day regimen. 2. 7 days of antibiotics may actually increase the risk of serious infection such as nosocomial pneumonia, and predispose to the development of infections with fungi or antibiotic resistant bacteria. 3. 2 days of prophylaxis is more beneficial than long term 7 day regimen for example economically.

• 대한예방의학회:학술대회논문집
• /
• 2000.10a
• /
• pp.126-127
• /
• 2000

• Journal of Dental Anesthesia and Pain Medicine
• /
• v.23 no.1
• /
• pp.54-54
• /
• 2023

• Journal of Dental Anesthesia and Pain Medicine
• /
• v.23 no.1
• /
• pp.57-57
• /
• 2023