• The Korean Journal of Applied Statistics
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• v.29 no.4
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• pp.595-611
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• 2016

We use nonlinear regression models (such as the Hill Model) when we analyze data in toxicology and/or pharmacology. In nonlinear regression models an estimator of parameters and estimation of measurement about uncertainty of the estimator are influenced by the variance structure of the error. Thus, estimation methods should be different depending on whether the data are homoscedastic or heteroscedastic. However, we do not know the variance structure of the error until we actually analyze the data. Therefore, developing estimation methods robust to the variance structure of the error is an important problem. In this paper we propose a method to estimate parameters in nonlinear regression models based on a preliminary test. We define an estimator which uses either the ordinary least square estimation method or the iterative weighted least square estimation method according to the results of a simple preliminary test for the equality of the error variance. The performance of the proposed estimator is compared to those of existing estimators by simulation studies. We also compare estimation methods using real data obtained from the National Toxicology program of the United States.

• Korean Journal of Digital Imaging in Medicine
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• v.12 no.1
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• pp.59-64
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• 2010

We examined the accuracy and efficiency of phantom by applying the designed phantom in order to check daily quality assurance easily by objective criteria and to confirm daily quality assurance of linear accelerator, simulator, and CT-simulator. The results of 10 weeks of linear accelerator output dose using American Association of Physicists in Medicine(AAPM) daily quality assurance guide were measured within ${\pm}1%$ of error. Mechanical check of laser alignment, optical distance indicator(ODI), CT scanner laser and alignment of gantry lasers with the center of imaging plane were measured within ${\pm}1mm$. Daily average working time for daily quality assurance of radiation therapy equipments was 38 minutes. The designed phantom was easy to install and daily quality assurance was possible with only one installation. The aspects reproducibility and efficiency as well as accuracy of quality assurance were excellent.

• Journal of Biomedical Engineering Research
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• v.24 no.1
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• pp.45-53
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• 2003

Based on the 4-compartmental pharmacokinetic model developed in PART1, target-controlled infusion(TCI) pump system was designed and evaluated. The TCI system consists of digital board including microcontroller and digital signal process(DSP), analog board, motor-driven actuator, user friendly interface, power management and controller. It provides two modes according to the drugs: plasma target concentration and effect target concentration. Anaesthetist controls the depth of anaesthesia for patients by adjusting the required concentration to maintain both plasma and effect site in drug concentration. The data estimated in DSP include infusion rate, initial load dose, and rotation number of motor encoder. During TCI operation, plasma concentration. effect site concentration, awaken concentration, context-sensitive decrement time and system error information are displayed in real time. Li-ion battery guarantees above 2 hours without power line failure. For high reliability of the system, two microprocessors were used to perform independent functions for both pharmacokinetic algorithm and motor control strategy.

• Journal of the Korea Safety Management & Science
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• v.18 no.1
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• pp.141-145
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• 2016

This study was to improve to utilization of non dosimetry measurements for X-ray radiography. Experiments was passed off varying the X-ray tube voltage and the thickness of the aluminum filter by actual dose. Calculated results was set to the first beam quality factors, calculated first correction coefficient by the Microsoft Excel program was set as the second beam quality factors. To make the non dosimetry measurements simply, the Excel program apply to the new beam quality factors, the error was compared to the previous studies, and the results verify the calculated value of smaller errors.

• Proceedings of the KIEE Conference
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• 2008.07a
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• pp.1779-1780
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• 2008

This paper presents a switching system of speed controller between PI (Proportional_Integrator) and P_LPF (Proportional_Low pass filter) to improve overshoot and slow settling time in DC motor. When the integrator is saturated in the PI controller, the error signal is integrated continuously. For preventing the state, the Anti-windup scheme is proposed. But the Anti-windup scheme dose not show stable characteristics in the whole speed command section after tuned a gain. By using P_LPF switching system these problems are improved and there is no need to tune of user hereafter, when the integrator is saturated. The proposed method is verified by the simulation results using MATLAB SIMULINK.

• Proceedings of the Korean Society of Precision Engineering Conference
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• 1995.04b
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• pp.262-266
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• 1995

This paper presents a new adaptive-neuro control scheme to control the velocity and position of SCARA robot with parameter uncertainties. The adaptive control of linear system found wiedly in many areas of control application. While techniques for the adaptive control of linear systems have been well-established in the literature, there are a few corresponding techniques for nonlinear systems. In this paper an attempt is made to present a newcontrol scheme for theadaptive control of ponlinear robot based on a feedforward neural network. The proposed approach incorporates a neuro controller used within a reinforcement learning framework, which reduces the problem to one of learning a stochastic approximation of an unknown average error surface Emphasis is focused on the fact that the adaptive-neuro controoler dose not need any input/output information about the controlled system. The simulation result illustrates the effectiveness of the proposed adaptive-neuro control scheme.

• The Journal of Korean Society for Radiation Therapy
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• v.3 no.1
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• pp.27-36
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• 1989

In order to calculate the dose on each interest point in five types of irregularly shaped fields used commonly in radiotherapy, the tissue-air ratios (TAR) in these fields for Go-60 gamma radiation were calculated using the newly devised SAR-chart. The TARs calculated from newly method of using the SAR-chart, computer method and approximation method at the interest point were compared to the TARs obtained from measurement. The result are as follows; In case of the interest points on central axis the calculated TARs in irregularly shaped fields by the above mentioned methods were well agreed within the error of $1\%$, whereas for the interest points on off-axis the calculated TARs were resulted in the maximum errors of $2.4\%,\;2.3\%$ and $8.8\%$ respectively. From these results, the accuracy of calculation method of using the SAR-chart was comfirmed.

• The Journal of Korean Institute of Communications and Information Sciences
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• v.27 no.8A
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• pp.753-762
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• 2002

Blind equalization of transmission channel is important in communication areas and signal processing applications because it does not need training sequences, nor dose it require a priori channel information. In this paper, an adaptive blind MMSE channel equalization technique based on second-order statistics in investigated. We present an adaptive blind MMSE channel equalization using multichannel linear prediction error method for estimating cross-correlation vector. They can be implemented as RLS or LMS algorithms to recursively update the cross-correlation vector. Once cross-correlation vector is available, it can be used for MMSE channel equalization. Unlike many known subspace methods, our proposed algorithms do not require channel order estimation. Therefore, our algorithms are robust to channel order mismatch. Performance of our algorithms and comparisons with existing algorithms are shown for real measured digital microwave channel.

• Journal of Korean Society of Water and Wastewater
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• v.20 no.6
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• pp.789-797
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• 2006

This study was conducted to establish the refined model for prediction of flocculation/sedimentation efficiency in factual drinking water treatment plants using model tree technique. In order to carry out machine leaning for determining each linear model, five parameters; time, coagulant dose, raw water turbidity, SCD and conductivity, which were measured and collected from the field (K_DWTP), were selected and used. The existing analytical models developed by previous researchers were used only to examine closely the mechanism of flocculation rather than to apply it for practical purpose. The refined model established using model tree technique in this study could predict the factual sedimentation efficiency accurately (below 9% of average absolute error). Also, in aspect of engineering convenience, without any additional manipulation of parameters, it can be applied to practical works.

• International Journal of Advanced Culture Technology
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• v.10 no.4
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• pp.23-244
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• 2022

The Pulpose of this systematic review is aimed to establish the procedure of the injection with saftey and efficiency in the pre-hospital cardiac arrest patient performing the cardiopulmonary resuscitation (CPR), compared with traditional medication administration using Ampoule and medication administration with Prefilled Syringe. Databases were searched for CPR, heart arrest, resuscitation, Pre-filled Syringe, and Ampoule by the electronic data research including Pubmed, EMBASE and Cochran Library of Konyang University Library: 4 articles were selected by three co-authors using EndNote X20 and Covidence (Covidence.org) and were systematically reviewed. The Result of this study, the medication administration using Pre-fillled Syringe improves the safety of patients and Emergency medical workers by reducing the error in administration dose and administering the drug in safe than the medication adminisrtaion using Ampoule, also, contributes to the increment of survival rate of cardiac arrest and severe patients by decreasing the administration time that prevents the delay of medication administration.