• 제목/요약/키워드: division type

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"동의보감(東醫寶鑑)"을 이용한 태음인(太陰人) 갈근해기탕(葛根解肌湯)의 적응증(適應證) 확장 연구(硏究) (Extended indications of Taeeum-type Galgeunhaegi-tang using "Dongeuibogam")

  • 박창환;이병욱;백진웅
    • 한국한의학연구원논문집
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    • 제18권2호
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    • pp.91-100
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    • 2012
  • Indications of Galgeunhaegi-tang(葛根解肌湯) for Taeeum-type on "Donguisusebowon" are small. Therefore, indications of Galgeunhaegi-tang for Taeeum-type need to be extended for broader clinical use. There would be some methods to do that, and we could review "Dongeuibogam" that Four-Constitution Medicine formulas are based on. We reviewed Galgeunhaegi-tang, which is the origin of Galgeunhaegi-tang, and their modified formula(加減方) on "Dongeuibogam". As a result, we supposed 10 indications of non-classical formula(後世方) Galgeunhaegi-tang as possible indications of Galgeunhaegi-tang for Taeeum-type.

Qualification of liquid crystal mixtures by bulk-state transient current analysis

  • Peng, Kang-Yung;Yin, Hsueh-Min;Lin, Yang-Chu;Wang, Yang-Long;Kung, Li-Wei;Chan, Meng-Xi;Cheng, Hsin-An;Liau, Wei-Lung;Lien, Alan
    • 한국정보디스플레이학회:학술대회논문집
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    • 한국정보디스플레이학회 2008년도 International Meeting on Information Display
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    • pp.855-858
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    • 2008
  • Transient current (TC) on bulk-state liquid crystal mixtures was measured. We found that TC is very sensitive to impurities and the features of TC curves depend on the type of contamination, from which the quality of materials can be definitely evaluated and the type of impurities can also be revealed.

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Sperm Fertility of Transgenic Boar Harboring hEPO Gene is Decreased

  • Park Chun-Gyu;Kim Sung-Woo;Lee Poong-Yeon;Han Joo-Hee;Lee Hyun-Gi;Byun Sung-June;Yang Boh-Suk;Lee Chang-Hyung;Lee Hoon-Taek;Chang Won-Kyong;Park Jin-Ki
    • Reproductive and Developmental Biology
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    • 제30권1호
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    • pp.27-34
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    • 2006
  • This study was conducted to compare the reproduction ability of the wild type boar and recombinant human erythropoietin (hEPO) transgenic boar semen. Ejaculated boar semen was analyzed by flow cytometry, Elisa and IVF methods. In experiment 1, flow cytometric analysis showed that the live sperm ratio of transgenic boar sperm significantly lower (P<0.05) than that of wild type boar after incubation at 20, 22, 24 and 26 hr. In experiment 2, the presence and levels of various cytokines (IL-6, IL-10 and $TNF-{\alpha}$) to related animal reproduction in the seminal and blood plasma were examined using specific enzyme immunoassay. There was no significant difference between both groups. In experiment 3, the fertilizing capacity and developmental ability of both boar sperm were compared. The transgenic boar sperm had a significantly low capacity of penetration, sperm-zona binding, embryo development, and blastocyst formation compared to wild type sperm (P<0.05). These results suggest that transgenic boar sperm harboring hEPO gene has low sperm viability than wild type boar, and it is a reason to decrease of fertility and litter size.

The Spectrum of GJB2 Mutations in Korean Patients with Genetic Hearing Loss: a Functional Study and Study of Cell Growth Control by Dominant Type of GJB2 Mutants

  • Jin, Hyun-Seok;Kim, Jong-Bae;Go, Sang-Hee;Lee, Mi-Young;Jung, Sung-Chul;Park, Hyun-Young;Park, Hong-Joon;Koo, Soo-Kyung
    • 대한의생명과학회지
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    • 제12권4호
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    • pp.311-318
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    • 2006
  • The GJB2 mutation is mostly recessive in non-syndromic hearing loss, but specific mutations display a dominant type and syndromic hearing impairment. Both U54K and R75Q mutations present a dominant type in pedigrees with associated skin disorders. The purpose of this study was to investigate whether two GJB2 mutations can exhibit a dominant-negative effect on the growth abrogation and the gap junctional intercellular communication capacity exerted by wild-type connexin 26. A specific mutant region of GJB2 showed a loss of gap junction activity and a dominant negative effect on wild-type GJB2. The two mutants exerted a dominant-negative effect on the GJIC capacity and have independently effected GJB2 regulated growth of Hela cells; however, they have no dominant-negative growth effect on wild-type GJB2. It is proposed that the different mechanisms of the dominant-negative effect on wild-type GJB2 involve cell growth and GJIC function. This study describes mutations found in Korean deaf patients and that are typical of other east Asian regions.

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간내 담도가 확장된 담관낭의 수술 후 간내 담도의 변화 (Postoperative Change of Intrahepatic Bile Duct Dilatation in Choledochal Cyst)

  • 정수민;김혜은;이철구;서정민;이석구
    • Advances in pediatric surgery
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    • 제15권1호
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    • pp.11-17
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    • 2009
  • Choledochal cyst is a congenital dilatation of the bile duct. Intrahepatic bile duct dilatation of type IVa by Todani's classification at the time of diagnosis resolved spontaneously after cyst excision and hepaticojejunostomy in many cases. It should be distinguished from the true cystic dilatation of the intrahepatic ducts, which tends to persist, albeit after some regression. We therefore studied postoperative intrahepatic duct dilatation changes in choledochal cyst. A total of seventy-six choledochal cysts were managed at the Division of Pediatric Surgery, Department of Surgery, Samsung Medical Center from May 1995 to December 2005. The ratio of males to females was 1:2.8. Preoperative radiologic diagnosis by Todani's classification was Type I (n=52, 68.4 %), II (n=1, 1.3 %), IVa (n=23, 30.3 %). Among fifty-five patients with intrahepatic bile duct dilatation we were able to follow up forty-eight by ultrasonography. Twenty-two patients were type IVa, and twenty-six patients were type I and showed intrahepatic duct dilatation. Mean follow-up duration was 35.3 months (9~105 months). Complete regression of dilated intrahepatic duct was observed in fifteen patients of type IVa and twenty-four patients of type I. Incomplete regression of dilated intrahepatic duct was observed in six patients in type IVa and two patients in type I. Only one patient in type IVa showed no change in ductal dilatation during a follow-up period of 15 months. We conclude that true type IVa is much less frequent than what was diagnosed preoperatively by imaging study. Therefore in type IVa patients who are diagnosed preoperatively the decision to perform liver resection should be carefully considered. Postoperative long term follow up of choledochal cyst with intrahepatic bile duct dilation is needed.

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$SiO_2$막의 습식식각 방법별 균일도 비교 (Comparison of Etching Rate Uniformity of $SiO_2$ Film Using Various Wet Etching Method)

  • 안영기;김현종;성보람찬;구교욱;조중근
    • 반도체디스플레이기술학회지
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    • 제5권2호
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    • pp.41-46
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    • 2006
  • Wet etching process in recent semiconductor manufacturing is devided into batch and single wafer type. Batch type wet etching process provides more throughput with poor etching uniformity compared to single wafer type process. Single wafer process achieves better etching uniformity by boom-swing injected chemical on rotating wafer. In this study, etching characteristics of $SiO_2$ layer at room and elevated temperature is evaluated and compared. The difference in etching rate and uniformity of each condition is identified, and the temperature profile of injected chemical is theoretically calculated and compared to that of experimental result. Better etching uniformity is observed with single wafer tool with boom-swing injection compared to single wafer process without boom-swing or batch type tool.

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THE QUEUE LENGTH DISTRIBUTION OF PHASE TYPE

  • Lim, Jong-Seul;Ahn, Seong-Joon
    • Journal of applied mathematics & informatics
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    • 제24권1_2호
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    • pp.505-511
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    • 2007
  • In this paper, we examine the Markov chain $\{X_k,\;N_k;\;k=0,\;1,...$. We show that the marginal steady state distribution of Xk is discrete phase type. The implication of this result is that the queue length distribution of phase type for large number of examples where this Markov chain is applicable and shows a queueing application by matrix geometric methods.

Overexpression of Cotton Glutathione S-Transferase (GST) cDNA and Increase of low Temperature and Salt Tolerance in Plants

  • Kang, Won-Hee;Jong Hwa kim;Lim, Jung-Dae;Yu, Chang-Yeon
    • Journal of Plant Biotechnology
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    • 제4권3호
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    • pp.117-122
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    • 2002
  • Cotton Glutathione S-Transferase(GST: EC 2.5.1.18) was cloned and Gh-5 cDNA was overexpressed in tobacco (Nicotiana tabacum) plants. The transformation of cotton GST in tobacco plant was confirmed by northern blot analysis. Type I and Type II transcript patterns were identified in Gh-5 transgenic tobacco plants. Type I transcripts was only discussed in this paper. Glutathione and 1-chloro-2,4-dinitrobenzene (CDNB) were used as the substrates, and the activity of GST in the type I transgenic plants was about 2.5-fold higher than the non-expressers and wild type tobacco plants. The expression of cotton GST in tobacco plants proved that Gh-5 could be translated into functional protein. Type I transgenic plants produced functional GST in the cells. Type I showed higher GST specific activity than Type II in the transgenic plants. Control and transgenic seedlings were grown in the growth chamber and under the light at 15$^{\circ}C$, and the effects of cotton GST in the seedlings was evaluated. The growth rate of Gh-5 overexpressors was better than the control and non-transgenic tobacco plants. Salinity tolerance was also analyzed on the seeds of transgenic plants. Seeds of Gh-5 overexpressors and the wild type tobacco seedlings were germinated and grown at 0, 50, 100, 150, and 200 mM NaCl solution. Gh-5 transgenic seedlings showed higher growth rate over control seedlings at both 50 and 100 mM NaCl solution. But at 0, 150, and 200 mM NaCl concentration, the difference in growth rate was not detected.