Bulletin of the Korean Chemical Society

Korean Chemical Society (대한화학회)
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Synthesis and Biological Evaluation of Isophthalamide Derivatives as T-type Calcium Channel Blockers

  • Oh, You-Na (Life Sciences Division, Korea Institute of Science and Technology) ;
  • Kim, Yoon-Jee (Life Sciences Division, Korea Institute of Science and Technology) ;
  • Seo, Seon-Hee (Life Sciences Division, Korea Institute of Science and Technology) ;
  • Lee, Jae-Kyun (Life Sciences Division, Korea Institute of Science and Technology) ;
  • Rhim, Hye-Whon (Life Sciences Division, Korea Institute of Science and Technology) ;
  • Pae, Ae-Nim (Life Sciences Division, Korea Institute of Science and Technology) ;
  • Jeong, Kyu-Sung (Department of Chemistry, College of Science, Yonsei University) ;
  • Choo, Hyun-Ah (Life Sciences Division, Korea Institute of Science and Technology) ;
  • Cho, Yong Seo (Life Sciences Division, Korea Institute of Science and Technology)
  • Published : 2008.10.20
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References

  1. Doering, D.; Zamponi, G.; Connolly, T. M.; Barrow, J. C.; Triggle, D. J.; Snutch, T. P. In Voltage-Gated Ion Channels as Drug Targets; Triggle, D. J., Gopalakrishnan, M., Rampe, D., Zheng, W., Eds.; Wiley-VCH: Weinhiem, 2006; Vol. 29, pp 65-149
  2. Park, S. J.; Park, S. J.; Lee, M. J.; Rhim, H.; Kim, Y.; Lee, J.- H.; Chung, B. Y.; Lee, J. Y. Bioorg. Med. Chem. 2006, 14, 3502 https://doi.org/10.1016/j.bmc.2006.01.005
  3. Furukawa, T.; Yamada, O.; Matsumoto, H.; Yamashita, T. WO2005051402, 2005
  4. Rhim, H.; Lee, Y. S.; Park, S. J.; Chung, B. Y.; Lee, J. Y. Bioorg. Med. Chem. Lett. 2005, 13, 283
  5. McCalmont, W. F.; Heady, T. N.; Patterson, J. R.; Lindenmuth, M. A.; Haverstick, D. M.; Gray, L. S.; MacDonald, T. L. Bioorg. Med. Chem. Lett. 2004, 14, 3691 https://doi.org/10.1016/j.bmcl.2004.05.011
  6. Jung, H. K.; Doddareddy, M. R.; Cha, J. H.; Rhim, H.; Cho, Y. S.; Koh, H. Y.; Jung, B. Y.; Pae, A. N. Bioorg. Med. Chem. 2004, 12, 3965 https://doi.org/10.1016/j.bmc.2004.06.011
  7. Kumar, P. P.; Stotz, S. C.; Paramashivappa, R.; Beedle, A. M.; Zamponi, G. W.; Rao, A. S. Mol. Pharmacol. 2002, 61, 649 https://doi.org/10.1124/mol.61.3.649
  8. Flatters, S. J. L. Drugs of Future 2005, 30, 573 https://doi.org/10.1358/dof.2005.030.06.915728
  9. Na, H. S.; Choi, S.; Kim, J.; Park, J.; Shin, H.-S. Mol. Cells 2008, 25, 242
  10. Bourinet, E.; Alloui, A.; Monteil, A.; Barrère, C.; Couette, B.; Poirot, O.; Pages, A.; McRory, J.; Snutch, T. P.; Eschalier, A.; Nargeot, J. EMBO J. 2005, 24, 315 https://doi.org/10.1038/sj.emboj.7600515
  11. Kim, H. S.; Kim, Y.; Doddareddy, M. R.; Seo, S. H.; Rhim, H.; Tae, J.; Pae, A. N.; Choo, H.; Cho, Y. S. Bioorg. Med. Chem. Lett. 2007, 17, 476 https://doi.org/10.1016/j.bmcl.2006.10.042
  12. Kim, T.; Choi, J.; Kim, S.; Kwon, O.; Nah, S. Y.; Han, Y. S.; Rhim, H. Biochem. Biophys. Res. Commun. 2004, 324, 401 https://doi.org/10.1016/j.bbrc.2004.09.069
  13. Kim, Y.; Seo, S.; Kim, D.; Rhim, H. The 11th Annual Conference & Exhibition, Geneva, Switzerland, Sep 1115 2005; Society for Biomolecular Screening: Danbury, CT, 2005; P07016
  14. Jo, M. N.; Seo, H. J.; Kim, Y.; Seo, S. H.; Rhim, H.; Cho, Y. S.; Cha, J. H.; Koh, H. Y.; Choo, H.; Pae, A. N. Bioorg. Med. Chem. 2007, 15, 365 https://doi.org/10.1016/j.bmc.2006.09.051
  15. Rhim, H.; Lee, Y. S.; Park, S. J.; Chung, B. Y.; Lee, J. Y. Bioorg. Med. Chem. Lett. 2005, 15, 283 https://doi.org/10.1016/j.bmcl.2004.10.078

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