• Title/Summary/Keyword: distribution science

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An in vitro study of mesenchymal stem cell proliferation on titanium discs coated with rhTGF-β2/PLGA by electrospray (Electrospray법으로 rhTGF-β2/PLGA 복합체를 코팅한 티타늄에서의 간엽줄기세포 증식에 관한 연구)

  • Kim, Joohyung;Kim, Seong-Kyun;Heo, Seong-Joo;Koak, Jai-Young;Lee, Woo-Sung;Lee, Joo-Hee;Park, Ji-Man
    • The Journal of Korean Academy of Prosthodontics
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    • v.54 no.2
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    • pp.120-125
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    • 2016
  • Purpose: The purpose of this study is to identify the effect of mesenchymal stem cell proliferation on recombinant human transforming growth factor-beta (rhTGF-${\beta}2$) / poly (D,L-lactide-co-glycolide) (PLGA) treated titanium discs by electrospray. Materials and methods: Anodized titanium surface coated with PLGA was used for a control group to compare anodized titanium surface coated with 125 ng/ml and 500 ng/ml rhTGF-${\beta}2$ as test groups. Atomic force microscope (AFM) test was utilized to determine the difference in coating surface roughness, and field-emission scanning electron microscopy (FE-SEM) was taken to visualize even distribution of coating particles on titanium discs. The mesenchymal stem cell proliferation was tested by using MTT (3-(4,5-dimethylthiazol-2-yl)-2,5 diphenyl-tetrazolium bromide) assay on 1st, 4th, 7th days. Results: According to AFM results, there was no statistically significant difference in titanium discs treated with PLGA and with rhTGF-${\beta}2$/PLGA (P>.05). MTT assay test results showed that there was statistically significant difference in mesenchymal stem cell proliferation on test groups compared to control groups at 7th day, and cell viability on discs coated with rhTGF-${\beta}2$ was significantly higher than control groups (P<.05). Conclusion: Titanium surface coated with rhTGF-${\beta}2$/PLGA shows statistically significant higher cell proliferation and the titanium surface coated with the higher concentration of rhTGF-${\beta}2$ presents faster cell growth activity.

A COMPARATIVE STUDY ON THE THEMATIC DISTRIBUTION OF THE ARTICLES PUBLISHED IN THE JOURNAL OF THE AMERICAN ACADEMY OF PEDIATRIC DENTISTRY AND THE JAPANESE SOCIETY OF PEDIATRIC DENTISTRY (90년대 이후 미국과 일본 소아치과학회지 게재논문의 분야별 분포에 관한 비교 연구)

  • Yeom, Junng-Hyun;Kim, Shin;Jeong, Tae-Sung
    • Journal of the korean academy of Pediatric Dentistry
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    • v.29 no.4
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    • pp.539-554
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    • 2002
  • To identify the trend of pediatric dentistry in USA and Japan, closely related to Korean pediatric dentistry. The Japanese Journal of Pediatric Dentistry(JJPD) and The Journal of the American Academy of Pediatric Dentistry(PD) were reviewed. We collected the bibliographical data of the articles published in the two journals from 1991 to 2000. We analyzed thematic distributions and chronological changes, and then compare those of two groups. The following results were obtained: 1. The 869 articles were published in JJPD and 672 in PD. This was about 30% more in JJPD. 2. In both JJPD and PD, the case reports were a quarter of scientific articles in quantity. 3. The studies on the systemic diseases had the highest proportion in both JJPD and PD. The studies on the dental caries and restorative materials also had high proportion in both journals. 4. The studies on the sedation and biochemical survey had high proportion in PD when had low proportion in JJPD. To the contrary, The studies on the behavior science in JJPD were about double of those in PD. 5. There was no statistically significant difference in quantity between JJPD and PD in the studies on the dental caries, prevention of dental caries, community dental survey, conservative treatment, restorative materials, pulp treatment, diagnosis and treatment of malocclusion, oral pathology and minor surgery, local anesthesia and nerve tissue, traumatic injuries. 6. There was statistically significant increase in the studies on the dental equipment in JJPD and in those on restorative materials in PD. 7. There was statistically significant decrease in the studies on the prevention of dental caries and local anesthesia and nerve tissue in JJPD, and those on conservative treatment in PD.

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Analysis on the Spatial Characteristics Caused by the Cropland Increase Using Multitemporal Landsat Images in Lower Reach of Duman River, Northeast Korea (다시기 위성영상을 이용한 두만강 하류지역의 농경지 개간의 공간적 특성분석)

  • Lee, Min-Boo;Han, Uk;Kim, Nam-Shin;Han, Ju-Youn;Shin, Keun-Ha;Kang, Chul-Sung
    • Journal of the Korean Geographical Society
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    • v.38 no.4
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    • pp.630-639
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    • 2003
  • This study aims to analysis the distribution and change of cropland and forest, the Onseong, Saebyeol, and Eundeok counties on the lower reach of Duman(Tumen) river, northeast Korea, using 1992 year Landsat TM data, 2000 year Landsat ETM data, and digital terrain elevation data(DTED). Land cover and land use of the study areas are classified into cropland, forest, village, and water body, using the supervised classification method including 1:50,000 DTED analysis, image band composition, and principal component analysis(PCA). Results of quantitative analysis present that each growth rate of cropland of Onseong and Eundeok are 22.8% and 14.7% corresponding to decreasing rates of forest, 8% and 13.6% during 8 years from 1992 to 2000. In Onseong, Saebyeol, and Eundeok, each values of mean elevations and slope gradients increased to 192m, 95m, and 91m from 157m, 85m, and 78m, and to 6.6$^{\circ}$, 3.0$^{\circ}$, and 4.4$^{\circ}$ from 5.2$^{\circ}$, 2.5$^{\circ}$, and 3.0$^{\circ}$. Especially, in case of newly developed cropland, the values of mean elevation and mean gradient have 225m, 122m, and 127m, and 9.4$^{\circ}$, 5.1$^{\circ}$, and 8.0$^{\circ}$, in above three regions. These new croplands were developing along to deeper valleys and toward lower hill and mountain slope up to knickpoint zone of gradient change. Deforested lands for cropland have formed irregular pattern of patch-type, and become sources for the sheet erosion, rilling and gulleying in mountain slope and sedimentation in local river channel. Though there were no field checking, analysis using landsat images and GIS mapping can help understand actual environmental problems relating to cropland development of mountain slope in North Korea.

Quantitative Conductivity Estimation Error due to Statistical Noise in Complex $B_1{^+}$ Map (정량적 도전율측정의 오차와 $B_1{^+}$ map의 노이즈에 관한 분석)

  • Shin, Jaewook;Lee, Joonsung;Kim, Min-Oh;Choi, Narae;Seo, Jin Keun;Kim, Dong-Hyun
    • Investigative Magnetic Resonance Imaging
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    • v.18 no.4
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    • pp.303-313
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    • 2014
  • Purpose : In-vivo conductivity reconstruction using transmit field ($B_1{^+}$) information of MRI was proposed. We assessed the accuracy of conductivity reconstruction in the presence of statistical noise in complex $B_1{^+}$ map and provided a parametric model of the conductivity-to-noise ratio value. Materials and Methods: The $B_1{^+}$ distribution was simulated for a cylindrical phantom model. By adding complex Gaussian noise to the simulated $B_1{^+}$ map, quantitative conductivity estimation error was evaluated. The quantitative evaluation process was repeated over several different parameters such as Larmor frequency, object radius and SNR of $B_1{^+}$ map. A parametric model for the conductivity-to-noise ratio was developed according to these various parameters. Results: According to the simulation results, conductivity estimation is more sensitive to statistical noise in $B_1{^+}$ phase than to noise in $B_1{^+}$ magnitude. The conductivity estimate of the object of interest does not depend on the external object surrounding it. The conductivity-to-noise ratio is proportional to the signal-to-noise ratio of the $B_1{^+}$ map, Larmor frequency, the conductivity value itself and the number of averaged pixels. To estimate accurate conductivity value of the targeted tissue, SNR of $B_1{^+}$ map and adequate filtering size have to be taken into account for conductivity reconstruction process. In addition, the simulation result was verified at 3T conventional MRI scanner. Conclusion: Through all these relationships, quantitative conductivity estimation error due to statistical noise in $B_1{^+}$ map is modeled. By using this model, further issues regarding filtering and reconstruction algorithms can be investigated for MREPT.

Bioecological Studies in the Upwelling Area of Cheju Island. ( I ) - Upwelling Phenomenon and Chemical Properties of Seawater in the Southwestern Coastal Area of Cheju Island (제주도 주변 용승역의 생물생태학적 기초연구 ( I )- 제주도 남서부 연안해역의 해수화학적 특성과 용승현상)

  • KANG Tae-Youn;CHOI Young-Chan;Go You-Bong
    • Korean Journal of Fisheries and Aquatic Sciences
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    • v.29 no.5
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    • pp.603-613
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    • 1996
  • Hydrographic conditions (temperature, salinity, dissolved oxygen), nutrients, chlorophyll-a and suspended solid have been studied in the southwestern coastal area of Cheju Island from April 1993 to March 1994. Vertical profile of temperature, salinity and chemical properties (nutrients, chlorophyll-a) distribution in th southwestern sea of Cheju Island showed a upwelling feature. Although it was not clear in winter season, it seems to continued through out the year. In the surface water at the upwelling areas, the ranges of dissolved oxygen, nitrate, phosphate and silicate was $3.30\~8.43\;ml/l,\;0\~7.12{\mu}g/l,\;0.03\~1.75{\mu}g-at/l\;and\;2.75\~22.32\;{\mu}g-at/l$l, respectively. Nutrients was higher in the shore water than in the offshore water, because sufficient supply of nutrients from the bottom water by coastal upwelling. In November, especially high concentration silicate was observed at all the stations and depth in the study area. At all station of bottom water (down to the depth of 60 meter), concentration value of dissolved of gen was as high as 8 ml/l. Mean values of N/P was 8.0, lower than Redifield ratio of 16. The mean values of Si/P was observed to 46.3 in southwest of Cheju Island. Concentration of chlorophyll-a was in the range of $0.04\~2.36\;{\mu}g/l$. Concentration of chlorophyll-a in surface orator at all station was especially higher in spring than in other seasons. Mean concentration value of suspended solids was 3.14 mg/l $(0.75\~8.47\;mg/l)$. Ratio of the volatile suspended solids to the suspended solids was higher in the inshore water $(53\%)$ than in the offshore water $(46\%)$, and higher in the surface water than in the bottom water.

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GIS Spatial Analysis of Vulnerability of Protected Cultivation Area to Meteorological Disaster : A Case Study of Jeollanambuk Province, South Korea (GIS를 이용한 시설재배의 기상재해 취약지역 해석 - 전라남북도의 사례를 중심으로 -)

  • Kim, Dong Hyeon;Kang, Dong Hyeon;Lee, Si Young;Son, Jin Kwan;Park, Min Jung;Yoon, Yong-Cheol;Yun, Sung-Wook
    • Journal of Bio-Environment Control
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    • v.26 no.2
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    • pp.87-99
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    • 2017
  • Recently the increase in an abnormal climate events and meteorological disasters which causes a great damage to greenhouse facilities. To minimize and evaluate the expected damages it is necessary to prepare countermeasures and a management system in advance. For this purpose, a quantitative analysis of weather and abnormal climate are needed to investigate protected cultivation areas which are vulnerable to natural disasters. This study focused on protected cultivation areas in Jeolla province, South Korea. Surrogate variables were calculated to analyze the vulnerable areas to meteorological disasters, and spatial distribution analysis was also performed by using GIS to present vulnerable areas on map. The map thus created and was compared with actual data of damages by meteorological disasters which occurred in target areas. The result of the comparison is as follows: About 50% of the target areas showed an agreement between the map created in this study and the actual data, these areas includes Gwangju metropolitan city, Naju city, Yeongam County, Jangseong County, Hampyeong County, and Haenam County. On the other hand, other areas, including Gunsan city, Mokpo city, and Muan County, suffered low damage in spite of high levels of vulnerability to meteorological disasters. This result was considered to be affected by such variables as different structural designs and management systems of greenhouses by region. This study carried out an analysis of meteorological data to find out more detailed vulnerability to protected cultivation area and to create a map of vulnerable protected cultivation areas. In addition, the map was compared with the record of natural disasters to identify actual vulnerable areas. In conclusion, this study can be utilized as basic data for preventing and reducing damages by meteorological disasters in terms of design and management of greenhouses.

Diffusion-weighted MR Imaging of Hypoxic-Ischemic Encephalopathy (저산소성-허혈성 뇌증의 확산강조영상 소견)

  • Choi, Hye-Young;Choi, Dae-Seob;Ryoo, Jae-Wook;Cho, Jae-Min;Ko, Eun-Sook;Shin, Tae-Beom;Na, Jae-Beom;Choi, Nak-Cheon
    • Investigative Magnetic Resonance Imaging
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    • v.12 no.1
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    • pp.49-54
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    • 2008
  • Purpose : The purpose of this study was to determine the characteristics of hypoxic-ischemic encephalopathy (HIE) on diffusion-weighted imaging (DWI) and the role of DWI for the diagnosis of HIE. Materials and Methods : Six patients with HIE underwent MRI including DWI. MR examinations were performed within 4 - 32 days (mean, 11.8 days) after hypoxic brain insult. We assessed the distribution of the lesions and compared the DWI and T2, FLAIR images for the subjective conspicuity of the lesions. Results : In all patients, symmetrical hyperintense lesions were demonstrated in the bilateral basal ganglia on T2, FLAIR, and DWI. On ADC map image, the lesions were hypointense in four of six patients and isointense in other two patients. Lesion conspicuity on DWI was higher than on T2 and FLAIR images in four of six patients and similar in other two patients. For the involvement of the cortex and subcortical white matter, in five of six patients, bilateral symmetric hyperintense lesions were seen on T2, FLAIR, and DWI. Lesion conspicuity on DWI was higher than on T2 and FLAIR images in three of them and similar in other two patients. On ADC map image, the lesions showed hypointensity in three of five patients and isointensity in other two patients. For the involvement of the deep cerebral white matter, T2, FLAIR, and DWI showed bilateral symmetric hyperintense lesions in four of six patients. Among them, Lesion conspicuity on DWI was higher than on T2 and FLAIR images in only one patient. Conclusion : HIE is characterized by symmetrical hyperintense lesions in the bilateral basal ganglia, cerebral cortex, and white matter on DWI and the lesions are more conspicuously demonstrated on DWI than on T2 and FLAIR images.

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Species Diversity Analysis of the Mushroom in Mt. Chiak (치악산 발생 버섯의 종 다양성 비교 분석)

  • Lee, Byung Kook;Eom, Ki Cheol;Seok, Soon Ja
    • The Korean Journal of Mycology
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    • v.41 no.2
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    • pp.57-66
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    • 2013
  • The mushrooms collected at seven areas of Mt. Chiak in 2002 and 2003 were classified to analyse the distribution and species diversity. Frequency (number of mushroom : N), number of species (S), relative species density (RSD), similarity index (C), richness index (R1), variety index (V1), evenness index (E2), and dominance index(D1) were investigated. Total N and S was 143 and 84, respectively. The RSD was 0.179 ~ 0.226 of the 7 areas. The yearly C of the total area (0.213) was 8.2%. more higher than the average C of 7 areas (0.131). The order in the coefficient of variation (CV) of the indicator for 7 areas was N (10.5%) > D1 (9.2%) > V1 (8.9%) > S (8.5%) > R1 (7.4%) > E2 (2.2%). The average R1 of the 7 areas was 5.36 with the range from 4.85 to 6.01, and 16.72 for the total area. The average V1 of the 7 areas was 16.24 with the range from 14.44 to 18.66, and 68.82 for the total area. The average E2 of the 7 areas was 0.95 with the range from 0.926 to 0.982, and 0.819 for the total area. The average D1 of the 7 areas was 0.071 with the range from 0.055 to 0.073, and 0.081 for the total area. The correlation between N and 5 kinds of diversity indicator (S, R1, V1, E2, D) was not statistically significant, but the correlation between R1, E2 and D1 was statistically significant each other.

Estimate of Heat Flux in the East China Sea (동지나해의 열속추정에 관한 연구)

  • KIM Young-Seup
    • Korean Journal of Fisheries and Aquatic Sciences
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    • v.29 no.1
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    • pp.84-91
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    • 1996
  • Heat flux of the East China Sea was estimated with the bulk method, the East China mount based on the marine meteorological data and cloud amount data observed by a satellite. Solar radiation is maximum in May and minimum in December. Its amount decreases gradually southward during the winter half year (from October to March), and increases northward during the summer half year (from April to September) due to the influence of Changma (Baiu) front. The spatial difference of long-wave radiation is relatively small, but its temporal difference is quite large, i.e., the value in February is about two times greater than that in July. The spatial patterns of sensible and latent heat fluxes reflect well the effect of current distribution in this region. The heat loss from the ocean surface is more than $830Wm^{-2}$ in winter, which is five times greater than the net radiation amount during the same period, The annual net heat flux is negative, which means heat loss from the sea surface, in the whole region over the East China Sea. The region with the largest loss of more than $400Wm^{-2}$ in January is observed over the southwestern Kyushu. The annual mean value of solar radiation, long-wave radiation, sensible and latent heat fluxes are estimated $187Wm^{-2},\;-52Wm^{-2},\;-30Wm^{-2}\;and\;-137Wm^{-2}$, respectively, consequently the East China Sea losses the energy of $32Wm^{-2}(2.48\times10^{13}W)$. Through the heat exchange between the air and the sea, the heat energy of $0.4\times10^{13}W$ is supplied from the air to the sea in A region (the Yellow Sea), $2.1\times10^{13}W$ in B region (the East China Sea) and $1.7\times10^{13}W$ in C region (the Kuroshio part), respectively.

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The Influence of Environmental Characteristics on the Fatness of Pacific Oyster, Crassostrea gigas, in Hansan-Koje Bay (한산${\cdot}$거제만의 환경특성이 양식 굴의 비만에 미치는 영향)

  • CHOI Woo-Jeung;CHUN Yong-Yull;PARK Jeung-Hum;PARK Yeong-Chull
    • Korean Journal of Fisheries and Aquatic Sciences
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    • v.30 no.5
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    • pp.794-803
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    • 1997
  • Long line suspended culture of oysters has been started commercially in Hansan-Koje Bay since 1969. However, its Annual production has been decreased and culturing periods extended in recent years. So, we investigated environmental parameters and food organisms to identity the causes of poor fatness of oysters in Hansan-Koje Bay from February to November, 1994. As the result, the Water quality of Hansan-Koje Bay was found to be good for culture. For example, the mean concentration of COD was $1.35mg/\ell$, phosphate phosphorus was $0.30{\mu}g-at/\ell$ and dissolved inorganic nitrogen was $4.68{\mu}g-at/\ell$. However, the Hwado island and the inner part of the Hansan-Koje Bay were found to be eutrophicated due to various contaminants transported by land-based activities. But in the central pan of the Hansan-Koje Bay where the oyster farms Have been developed densely, the level of nutrient concentration was very low. During the study period, the dominant species of phytoplankton was Chaetoceros spp. with the percentage of $72.6\%\~87.8\%$ and the mean values of Chlorophyll-a concentration and phytoplankton standing crops were $2.05mg/m^3\;and\;188ind./m\ell$, respectively. The distribution of these parameters also showed similar trends those of nutrients. Especially, chlorophyll-a contents was very low with the concentration of below $0.5mg/m^3$ at central part of the Bay, Juklimpo. The fatness of oysters and the eutrophic index in this area were $18.1\%$ and 0.54, respectively. These values were lower than those of other culturing farms in the southern coastal areas in Korea. Therefore, we estimated that the insufficient food supply due to the low level of nutritional status was the major factors affecting the poor fatness of the Pacific oysters in Hansan-Koje Bay.

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