• 제목/요약/키워드: distribution coefficient($K_D$)

검색결과 231건 처리시간 0.026초

치기공과 교육과정의 개선 방안 - 재학생을 중심으로 - (Departments of Dental Technology An improvement plan of Curriculum - Focus on students who being in college -)

  • 배봉진;이화식;박명호
    • 대한치과기공학회지
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    • 제29권2호
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    • pp.49-64
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    • 2007
  • This research collected the curriculum for Dental Technology from a total of 20 schools -3-year colleges and 4-year colleges- all in Korea. And we analyzed the average credits of subjects from students. As a result of this analysis, we get the conclusion below: 1. In a distribution which students answered about each subjects; Seminar, Dental morphology I II, Dental morphology practice I II, and Dental devices & instruments don't have many credits and mostly have a converged tendency in high points, according to the arithmetic mean of the major basis subjects. 2. In an analysis of the correlation which is based on the distinction of sex: Complete denture prosthodontics I II III, Dental orthodontics I II, Dental orthodontics practice I II, and Dental orthodontics & practice III have a meaningful difference. ($\rho$< 0.05 ) 3. In an analysis of the correlation which is based on an age The major basis subjects -Introduction to dental technology, Dental esthetic, and Dental casting procedure-, and the major application subjects -Crown and bridge prosthodontics practice, Complete denture prosthodontics, Dental orthodontics, Dental orthodontics practice, and Operative dentistry laboratory technology- have meaningful difference. ($\rho$< 0.05 ) 4. In a correlation coefficient between subjects; The correlation coefficient of the major application subjects is higher than the major basis subjects. According to the student - t, we found that the level of significance is $\rho$< 0.001, which is meaningful. We feel the lack of a limitation which we didn't survey all students who are major in Department of Dental Technology. And we also feel that we'd better to consider not only students who being in college but also graduated students.

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Microemulsion-based hydrogels for enhancing epidermal/dermal deposition of topically administered 20(S)-protopanaxadiol: in vitro and in vivo evaluation studies

  • Kim, Ki-Taek;Kim, Min-Hwan;Park, Ju-Hwan;Lee, Jae-Young;Cho, Hyun-Jong;Yoon, In-Soo;Kim, Dae-Duk
    • Journal of Ginseng Research
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    • 제42권4호
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    • pp.512-523
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    • 2018
  • Background: 20(S)-Protopanaxadiol (20S-PPD) is a fully deglycosylated ginsenoside metabolite and has potent dermal antiaging activity. However, because of its low aqueous solubility and large molecular size, a suitable formulation strategy is required to improve its solubility and skin permeability, thereby enhancing its skin deposition. Thus, we optimized microemulsion (ME)-based hydrogel (MEH) formulations for the topical delivery of 20S-PPD. Methods: MEs and MEHs were formulated and evaluated for their particle size distribution, morphology, drug loading capacity, and stability. Then, the deposition profiles of the selected 20S-PPD-loaded MEH formulation were studied using a hairless mouse skin model and Strat-M membrane as an artificial skin model. Results: A Carbopol-based MEH system of 20S-PPD was successfully prepared with a mean droplet size of 110 nm and narrow size distribution. The formulation was stable for 56 d, and its viscosity was high enough for its topical application. It significantly enhanced the in vitro and in vivo skin deposition of 20S-PPD with no influence on its systemic absorption in hairless mice. Notably, it was found that the Strat-M membrane provided skin deposition data well correlated to those obtained from the in vitro and in vivo mouse skin studies on 20S-PPD (correlation coefficient $r^2=0.929-0.947$). Conclusion: The MEH formulation developed in this study could serve as an effective topical delivery system for poorly soluble ginsenosides and their deglycosylated metabolites, including 20S-PPD.

수산음향기법의 주파수에 따른 남해안의 어류의 군집 및 공간분포 특징 (Properties of aggregation and spatial distribution of fish in the South Sea of Korea using hydroacoustic data)

  • 황강석;박정호;이정훈;차형기;박준성;강명희
    • 수산해양기술연구
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    • 제52권4호
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    • pp.325-338
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    • 2016
  • Properties of aggregation and spatial distribution of fish were examined based on three lines in the South Sea of Korea using three frequencies (18, 38, and 120 kHz) of a scientific echosounder. The vertical distribution of fish was displayed using acoustic biomass namely nautical area scattering coefficient (NASC). As a result, at 120 kHz high NASC showed from water surface to 20 meters in deep while at 18 and 38 kHz very high NASC presented in 70 ~ 90 meters in depth, especially at line 3. Among three lines, the line 2 had lowest NASC. The horizontal distribution of fish using three frequencies together exhibited high NASC between the eastern South Sea and center of South Sea. In especial, NASC ($801{\sim}1,920m^2/n{\cdot}mile^2$) was observed along coastal waters from Busan to Tongyeong, Geoje, and Namhae. In regard with the property of aggregation of fish schools, the volume back-scattering strength ($S_V$) of three lines presented close each other, however, the range of $S_V$ in the line 2 was shortest (-53.5 ~ -43.4 dB). The average distributional depth was deep in the order of L3 ($32.8{\pm}9.0m$), L1 ($45.2{\pm}9.5m$), L2 ($49.7{\pm}5.6m$). The average altitude was high in the order of L3 ($13.4{\pm}10.3m$), L1 ($17.0{\pm}12.6m$), L2 ($56.7{\pm}5.6m$). The average length, thickness, and area were large in the order of L1, L3, and L2. This means that small sized fish schools were distributed near water surface in the line 2 while relatively large and similar sized fish aggregations between line 1 and line 3 appeared however, fish schools at line 3 had lower distributional depth and smaller compared to those at line 1. Acoustic data were visualized for demonstrating the entire circumstances of survey area. Additionally, there was no correlation between acoustic and trawl results.

아질산성질소 축정용 FIA의 제작 및 용용에 관한 연구 (광주광역시 광주천 시료를 대상으로) (A Study on the Constitution and the Application of FIA System for Measurement of Nitrite (The Field Water Samples at Kwangju))

  • 이재성;박완철;이수원;김용준
    • 한국물환경학회지
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    • 제18권3호
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    • pp.283-290
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    • 2002
  • In this study, home-made detection system by means of noble FIA is introduced on the measurement of toxic nitrite in the water samples collected from the area of Kwangju. As the standard calibration between 30 to 1000 ppb, the linearity has been shown more than 0.9999 as the correlation coefficient($R^2$) with the detection limit 1.5 ppb(S/N>2). The distribution of sample concentration was monitored as N.D. - 123 ppb which is wide span of concentrations in field water samples. The low level of nitrite is hardly detectable with other expensive sophisticated instruments including ion chromatography. Whereas the result of high concentration brings forth the necessity monitoring constantly our precious water resources. Successfully, the FIA system has played a very important role detecting wide span of nitrite in water sample. This technique can be adopted for controlling our environment in the near future.

Numerical simulation of aerodynamic characteristics of a BWB UCAV configuration with transition models

  • Jo, Young-Hee;Chang, Kyoungsik;Sheen, Dong-Jin;Park, Soo Hyung
    • International Journal of Aeronautical and Space Sciences
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    • 제16권1호
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    • pp.8-18
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    • 2015
  • A numerical simulation for a nonslender BWB UCAV configuration with a rounded leading edge and span of 1.0 m was performed to analyze its aerodynamic characteristics. Numerical results were compared with experimental data obtained at a free stream velocity of 50 m/s and at angles of attack from -4 to $26^{\circ}$. The Reynolds number, based on the mean chord length, is $1.25{\times}106$. 3D multi-block hexahedral grids are used to guarantee good grid quality and to efficiently resolve the boundary layer. Menter's shear stress transport model and two transition models (${\gamma}-Re_{\theta}$ model and ${\gamma}$ model) were used to assess the effect of the laminar/turbulent transition on the flow characteristics. Aerodynamic coefficients, such as drag, lift, and the pitching moment, were compared with experimental data. Drag and lift coefficients of the UCAV were predicted well while the pitching moment coefficient was underpredicted at high angles of attack and influenced strongly by the selected turbulent models. After assessing the pressure distribution, skin friction lines and velocity field around UCAV configuration, it was found that the transition effect should be considered in the prediction of aerodynamic characteristics of vortical flow fields.

Alachlor 와 Paraquat 의 토양흡착(土壤吸着)에 관여(關與)하는 토양인자(土壤因子)에 대한 연구(硏究) (Studies on the Several Soil Factors Affecting on Alachlor and Paraquat Adsorption by Soils)

  • 임수길;봉원애
    • 한국환경농학회지
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    • 제11권2호
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    • pp.101-108
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    • 1992
  • 토양에 따른 제초제의 흡착을 구명하기 위하여 alachlor와 paraquat를 사용하여 공시토양 22에 대한 약제별 흡착정도 및 토양특성과 흡착정도의 상관을 조사한 결과는 다음과 같다. 1. 진탕시간에 따른 토양과 약제의 평형이 이루어지는 시간은 paraquat가 약 30분, alachlor는 약 4시간이었다. 2. 분배법칙에 의한 alachlor의 흡착계수는 5ppm 농도에서 0.81-33.83이었으며, 50ppm에서는 0.09-15.52의 범위를 나타내었다. 3. 토양특성중 alachlor의 흡착력은 O.M.함량, paraquat의 흡착력은 점토함량과 고도의 정의 상관을 보였다. 4. 우리나라 토양중 춘포통은 유기물과 점토함량이 낮음에도 특이한 특성 때문에 paraquat와 alachlor 모두 높은 흡착량을 나타내었다. 5. Freundlich의 흡착상수(K)는 분배법칙의 계수(Kd)보다 대체적으로 높으며, 평형농도가 증가함에 따라 K와 Kd값의 차이는 증가하는 경향이었다.

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사용자 평형을 이루는 통행분포와 통행배정을 위한 유전알고리즘 (A Genetic Algorithm for Trip Distribution and Traffic Assignment from Traffic Counts in a Stochastic User Equilibrium)

  • Sung, Ki-Seok
    • 한국경영과학회:학술대회논문집
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    • 한국경영과학회 2006년도 추계학술대회
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    • pp.599-617
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    • 2006
  • 혼잡한 교통네트워크에서 조사된 통행량으로부터 확률적 사용자 평형을 이루는 통행분포와 통행배정을 동시에 구하기 위한 네트워크 모델과 유전알고리즘을 제안하였다. 확률적 사용자 평형을 이루는 모델은 선형제약을 가진 비선형 목적함수를 최소화하는 문제로 정식화하였다. 네트워크 모델에서는 해의 탐색공간을 줄이고 조사된 통행량을 만족시키기 위해서 흐름보존제약을 활용하였다. 목적함수는 흐름보존, 통행발생량, 통행유입량, 조사통행량 등의 제약을 만족하는 링크통행량과, 경로통행배정을 통하여 구한, 확률적 사용자 평형을 이루는 경로통행량을 만족하는 링크통행량의 차이를 최소화하는 것으로 정식화하였다. 제안된 유전알고리즘에서 유전자는 통행분포, 링크통행량, 여행비용계수 등을 나타내는 벡터로 정의하였다. 각 유전자는 목적함수의 값으로 구한 적합도에 따라 평가되며, 병행단체교차와 돌연변이에 의하여 진화한다.

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Photoelectron Imaging Spectroscopy for (2+1) Resonance-Enhanced Multiphoton Ionization of Atomic Bromine

  • Kim, Yong-Shin;Jung, Young-Jae;Kang, Wee-Kyung;Jung, Kyung-Hoon
    • Bulletin of the Korean Chemical Society
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    • 제23권2호
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    • pp.189-194
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    • 2002
  • Two-photon resonant third photon ionization of atomic bromine $(4p^5\;^2P_{3/2}\;and\;^2P_{1/2})$ has been studied using a photoelectron imaging spectroscopy in the wavelength region 250 - 278 nm. The technique has yielded simultaneously both relative branching ratios to the three levels of $Br^+(^3P_2,\;^3P_{0.1}\;and^1D_2)$ with $4p^4$ configuration and the angular distributions of outgoing photoelectrons. The product branching ratios reveal a strong propensity to populate particular levels in many cases. Several pathways have been documented for selective formation of $Br^+(^3P_2)$ and $Br^+(^3P_{0.1})$ ions. In general, the final ion level distributions are dominated by the preservation of the ion core configuration of a resonant excited state. Some deviations from this simple picture are discussed in terms of the configuration interaction of resonant states and the autoionization in the continuum. The photoelectron angular distributions are qualitatively similar for all transitions, with a positive $A_2$ anisotropy coefficient of 1.0-2.0 and negligible $A_4$ in most cases, which suggests that the angular distribution is mainly determined by the single-photon ionization process of a resonant excited state induced from the third photon absorption.

프로젝트 인도율 그룹 분할 방법을 이용한 소프트웨어 개발노력 추정 (Software Development Effort Estimation Using Partition of Project Delivery Rate Group)

  • 이상운;노명옥;이부권
    • 정보처리학회논문지D
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    • 제9D권2호
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    • pp.259-266
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    • 2002
  • 소프트웨어 개발시 중요하게 제기되는 문제점으로 소프트웨어 생명주기의 초기단계에서 개발에 투입될 노력과 비용을 추정하는 능력이다. 측정된 소프트웨어 규모인 기능점수 (FP, Function Point)로부터 프로젝트 개발에 소요되는 노력과 비용을 추정하는 회귀모델들이 제안되었다. 그러나 이들 제안된 모델들은 사용한 표본의 크기가 작고, 과거에 개발된 프로젝트를 대상으로 하고 있다. 1990년대에 개발된 789개 소프트웨어 개발 프로젝트들에 투입된 개발노력에 이들 모델을 적용한 결과 결정계수 $R^2$가 0.53 이하로 데이터의 변동을 설명하였다. 본 논문은 프로젝트 인도율(PDR)을 이용하여 동질성을 갖는 그룹으로 분류하여 개발노력을 추정하는 모델을 제안하였다. 제안된 모델은 랜덤한 잔차 분포를 갖고 있고, 대부분의 PDR 범위에서 0.99이상의 결정계수로 데이터의 변동을 설명하였다.

공간곡선보요소에서의 감차최소화 이론 (Reduced Minimization Theory in Skew Beam Element)

  • 문원주;김용우;민옥기;이강원
    • 대한기계학회논문집A
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    • 제20권12호
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    • pp.3792-3803
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    • 1996
  • Since the skew beam element has two curvatures which are a curvature and a torsion, spatial behavior of curved beam which cannot be included in one plane can be anlayzed by emploting the skew beam element. The $C^{0}$-continuous skew beam element shows the stiffness locking phenomenon when full integration is employed. The locking phenomenpn is characterized by two typical phenomena ; one is the much smaller displacement thant the exact one and theother is the undelation phenomenon is stress distribution. In this paper, we examine how unmatched coefficient in the constrained energy brings about the locking by Reduced Minimization theory. We perform the numerical ones. These comparisons show that uniformly full integration(UFI), which employs full integration for the constrained energy, entails the locking phenomenon. But the use of uniformly reduced integration(URI) of selectively reduced integration(SRI), which employs reduced integration for constrained energy, does not produce the significant errors of displacements of the undulation phenomenon in stress distribution since they do not entails the locking, Additionally, the error due to the approximated parameters for describing the geometry of skew beam is examined.d.