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The Load Distribution Characteristics of Pile Group under Lateral Loading (수평력을 받는 무리말뚝의 하중분담특성)

  • Ahn, Byungchul;Oh, Sewook
    • Journal of the Korean GEO-environmental Society
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    • v.11 no.3
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    • pp.17-22
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    • 2010
  • This paper analyzed the characteristics of p-multiplier and the load distribution of H-pile group installed in weathered soil under horizontal loading. The results of this study conducted in pile arrangement ($2{\times}3$, $3{\times}3$), the pile center to center spacing (2D, 4D, 6D), and soil density (relative density: 40%, 80%) were drawn as follows. As to the average horizontal loading applied to each pile in pile groups, the fewer number of piles was, the larger average horizontal resistance became. As the result of analysis on p-y curves of single piles and pile groups according to the pile distance and the soil density, as the pile spacing was increased from 2D to 6D, the interaction coefficients of pile group showed 0.85~0.94 (piles in the front row), 0.57~0.79 (piles in the middle row), and 0.60~0.71 (piles in the rear row) in the loose ground and showed 0.76~0.82 (piles in the front row), 0.58~0.73 (piles in the middle row), and 0.53~0.70 (piles in the rear row) in the dense ground. As above, the wider pile distance was, the larger interaction coefficient value was shown among piles. In addition, piles in the front row showed bigger interaction coefficients than that of piles in the middle and back row.

The Structural Studies of Biomimetic Peptides P99 Derived from Apo B-100 by NMR

  • Kim, Gil-Hoon;Won, Ho-Shik
    • Journal of the Korean Magnetic Resonance Society
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    • v.24 no.4
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    • pp.136-142
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    • 2020
  • Apolipoprotein B-100 (apo B-100), the main protein component that makes up LDL (Low density lipoprotein), consists of 4,536 amino acids and serves to combine with the LDL receptor. The oxidized LDL peptides by malondialdehyde (MDA) or acetylation in vivo were act as immunoglobulin (Ig) antigens and peptide groups were classified into 7 peptide groups with subsequent 20 amino acids (P1-P302). The biomimetic peptide P99 (KGTYG LSCQR DPNTG RLNGE) out of B-group peptides carrying the highest value of IgM antigens were selected for structural studies that may provide antigen specificity. Circular Dichroism (CD) spectra were measured for peptide secondary structure in the range of 190-260 nm. Experimental results show that P99 has pseudo α-helice and random coil structure. Homonuclear (COSY, TOCSY, NOESY) 2D-NMR experiments were carried out for NMR signal assignments and structure determination for P99. On the basis of these completely assigned NMR spectra and proton distance information, distance geometry (DG) and molecular dynamic (MD) were carried out to determine the structures of P99. The proposed structure was selected by comparisons between experimental NOE spectra and back-calculated 2D NOE results from determined structure showing acceptable agreement. The total Root-Mean-Square-Deviation (RMSD) value of P99 obtained upon superposition of all atoms were in the set range. The solution state P99 has mixed structure of pseudo α-helix and β-turn(Gln[9] to Thr[13]). These NMR results are well consistent with secondary structure from experimental results of circular dichroism. Structural studies based on NMR may contribute to the prevent oxidation studies of atherosclerosis and observed conformational characteristics of apo B-100 in LDL using monoclonal antibodies.

The Structural Studies of Peptide P143 Derived from Apo B-100 by NMR

  • Lee, Ji-Eun;Kim, Gil-Hoon;Won, Ho-Shik
    • Journal of the Korean Magnetic Resonance Society
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    • v.25 no.4
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    • pp.58-63
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    • 2021
  • Apolipoprotein B-100 (apo B-100), the main protein component that makes up LDL (Low density lipoprotein), consists of 4,536 amino acids and serves to combine with the LDL receptor. The oxidized LDL peptides by malondialdehyde (MDA) or acetylation in vivo act as immunoglobulin (Ig) antigens and peptide groups were classified into 7 peptide groups with subsequent 20 amino acids (P1-P302). The biomimetic peptide P143 (IALDD AKINF NEKLS QLQTY) out of C-group peptides carrying the highest value of IgG antigens were selected for structural studies that may provide antigen specificity. Experimental results show that P143 has β-sheet in Ile[1]-Asn[9] and α-helice in Gln[16]-Tyr[20] structure. Homonuclear 2D-NMR (COSY, TOCSY, NOESY) experiments were carried out for NMR signal assignments and structure determination for P143. On the basis of these completely assigned NMR spectra and proton distance information, distance geometry (DG) and molecular dynamic (MD) were carried out to determine the structures of P143. The proposed structure was selected by comparisons between experimental NOE spectra and back-calculated 2D NOE results from determined structure showing acceptable agreement. The total Root-Mean-Square-Deviation (RMSD) value of P143 obtained upon superposition of all atoms were in the set range. The solution state P143 has a mixed structure of pseudo α-helix and β-turn(Phe[10] to Glu[12]). These results are well consistent with calculated structure from experimental data of NOE spectra. Structural studies based on NMR may contribute to the prevent oxidation studies of atherosclerosis and observed conformational characteristics of apo B-100 in LDL using monoclonal antibodies.

Effects of Virtual Reality Horse Riding Simulator Training Using a Head-Mounted Display on Balance and Gait Functions in Children with Cerebral Palsy: A Preliminary Pilot Study

  • Kim, Hae Won;Nam, Ki Seok;Son, Sung Min
    • The Journal of Korean Physical Therapy
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    • v.31 no.5
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    • pp.273-278
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    • 2019
  • Purpose: The purpose of this study was to investigate the effects of three-dimensional virtual reality horse riding simulator training using a head-mounted display on gait and balance in children with cerebral palsy. Methods: Ten children with cerebral palsy were randomly assigned to the horse riding simulator (HRS) group (n=5) or the horse riding simulator with virtual reality (HRSVR) group (n=5). To evaluate balance, center of gravity (COG) sway velocity and total sway distance of each group were assessed using the Wii balance board, and gait speed and stride length of each group were assessed using a gait analysis system. Results: Intra-group comparisons between pre- and post-intervention measures revealed that there were significant changes in all gait and balance variables such as stride length, gait velocity, COG sway velocity and COG sway distance in the HRSVR group (p<0.05). In the HRS group, there were significant changes in all variables except stride length (p<0.05). In addition, inter-group comparisons showed significant differences between the two groups in stride length, gait velocity and COG sway distance except COG sway velocity (p<0.05). Conclusion: The findings of this study suggest that horse riding simulator training combined with 3D virtual reality can be a new positive therapeutic approach for improving functional performance in children with cerebral palsy.

Dielectric Strength for Imitation Air with Pressure Variation under Uniform and Non-Uniform Fields (평등/불평등 전계하의 제조공기(I-Air)에 대한 압력별 절연파괴강도 특성)

  • Lee, Chang-Uk;Lee, Chang-Hun;Choi, Eun-Hyuck;Lee, Sang-Ho;Lee, Kwang-Sik
    • Proceedings of the Korean Institute of IIIuminating and Electrical Installation Engineers Conference
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    • 2007.11a
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    • pp.263-266
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    • 2007
  • In this paper approves (AC and DC) high voltage by experimental GIS(Gas Insulated Switchgear) chamber and (AC and DC) power source to study breakdown characteristics by pressure(P) change and change of electrode distance(d) at (AC and DC) high voltage of Imitation I-Air, $N_2$ : $O_2$ = 79(%) : 21[%]) to alternate $SF_6$ and achieved research. Gave P change of I-Air to study I-Air's Dielectric Strength using uniform and non-uniform fields(sphere-sphere and Needle-Plane electrode) and studied relations dielectric strength($V_D$) by each P different d.

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An Experimental Study on the Optimistic Recognition Level of Public Address System as a Soundscape Application Facility (사운드스케이프 적용을 위한 옥외 P.A. 시스템의 적정 인지레벨에 관한 실험적 연구)

  • Song, Min-Jeong;Jang, Gil-Soo
    • Transactions of the Korean Society for Noise and Vibration Engineering
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    • v.17 no.11
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    • pp.1050-1055
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    • 2007
  • P.A.(public address) system is considered as an useful active soundscape appliance which can gives a place identity and vitality by introducing conventional musics, environmental musics, bird singing sounds etc. In this study, the main aim is to know the optimistic distance from the speaker and sound pressure level range of introducing sound. So, the sound pressure level of P.A. system due to distances were measured and subjects' responses with level variations were checked. The main results are as follows. Level range from 64 dB to 71 dB is comfortable for subjects. And the optimal level of introducing sound is related with sound source characteristics. The results of this study could be used for street furniture location design and P.A. system output level.

Analysis on mandibular movement using the JT-3D system (JT-3D system을 이용한 하악의 운동 분석)

  • Song, Joo-Hun;Kim, Ryeo-Woon;Byun, Jae-Joon;Kim, Hee-Jung;Heo, Yu-ri;Lee, Gyeong-Je
    • Journal of Dental Rehabilitation and Applied Science
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    • v.36 no.2
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    • pp.80-87
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    • 2020
  • Purpose: This study aims to measure the mandibular movement using JT-3D system and provide a range of mandibular movement that can serve as a good reference for diagnosing the temporomandibular disorder. Materials and Methods: This study was conducted in 60 young male and female adults. The maximum opening and closing movement was recorded using JT-3D system, and by regarding 5 times of repetitive movement as 1 cycle of movement, total 3 cycles of movement were recorded. During the maximum opening, vertical position of lower jaw, antero-posterior position, lateral deflection position, and maximum opening distance were recorded. To evaluate the reproducibility of JT-3D system, statistical analysis were conducted (α = 0.05). Results: During the maximum opening, the average value appeared at 31.56 mm vertically and 24.42 mm rearwardly, lateral deflection position 0.72 mm, and maximum opening distance 40.32 mm. There was no statistical significance in all measured values for three cycles of movement recorded with JT-3D system (P > 0.05). Conclusion: During the maximum opening, the average value appeared at 0.72 mm in lateral deflection position and the maximum opening distance at 40.32 mm, and the analysis on the maximum opening of lower jaw using JT-3D system showed sufficiently reproducible results.

A Study on the Reliability of Corrected Diopter according to Subjective refraction instrument (자각식굴절검사기기에 따른 교정굴절력의 신뢰도에 관한 연구)

  • Lee, Hark-Jun;Kim, Jung-Hee;Ryu, Kyung-Ho
    • Journal of Korean Ophthalmic Optics Society
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    • v.15 no.3
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    • pp.281-286
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    • 2010
  • Purpose: This research provided basic data for refraction by comparing the corrected diopter of trial lens and phoropter. Methods: We compared the corrected diopter of trial lens and phoropter, and analyzed statistical significance and relations of the spherical lens corrected diopter and cylindrical lens corrected diopter according to the types (trial lens and phoropter) of subjective refractive instruments. Also we analyzed statistical significance and relations between cylindrical lens corrected diopter at the astigmatism and the types (trial lens and phoropter) of subjective refractory instruments. Results: When we measured the corrected diopter of simple myopia, the mean value for corrected diopter was S-2.74D using the trial lens and S-2.65D using the phoropter. So the corrected diopter was 0.09D smaller when measured by phoropter. The degree of astigmatism was measured C-0.81D using the trial lens and C-0.77D using the phoropter which showed that the measured value was 0.04D smaller using the phoropter. On correlation analysis between the refractive instruments (trial lens and phoropter) and the corrected diopter, there was significant (p<0.01) strong correlation between refractory machine and corrected spherical diopter (r=0.996) and the correlation between refractory machine and corrected cylindrical diopter was r=0.986 and was also significant (p<0.01). Conclusions: The use of phoropter than trial lens was more desirable when performing refraction on high myopia (simple refractive error, high astigmatism), and when using trial lens, you should consider the vertex distance and the gap between overlapped lenses before prescription.

Assessment of Dynamic Stereoacuity of Adults in their 20s' with Howard-Dolman Test (하워드-돌먼 입체검사를 이용한 20대 성인의 동적 입체시 평가)

  • Shim, Hyun-Suk;Choi, Sun-Mi;Kim, Young-Cheong
    • Journal of Korean Ophthalmic Optics Society
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    • v.20 no.1
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    • pp.61-66
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    • 2015
  • Purpose: In this study, dynamic stereoacuity of 20s' adults were measured by using the Howard-Dolman test(H-D TEST, Bernell, U.S.A), and compared of male and female. And the correlation between dynamic stereoacuity and PD(pupillary distance), and between dynamic stereoacuity and anisometropia caused by difference in the spherical refractive power of the left and right eyes were analyzed. Methods: The mean age of $22.68{\pm}0.50$(20~29)years old, 20s' 63 adults (30 male, 33 female) were conducted for this experiments. After the full correction of subject's refractive error, dynamic stereoacuity was measured 5 times for 1 subject at 2.5 m distance using the H-D test. at 2.5 distance. Results: The mean of dynamic stereoacuity was $28.44{\pm}25.03$ sec of arc for total subjects, $28.23{\pm}23.34$ sec of arc for male, and $28.63{\pm}26.83$ sec of arc for female. In the dynamic stereoacuity classified by the range of inter-pupil distance (IPD), the dynamic stereoacuity was $33.87{\pm}18.53$ sec for the IPD being under 59.80 mm, $26.24{\pm}25.26$ sec of arc for 59.81~66.15 mm, $34.60{\pm}25.65$ sec of arc for over 66.15 mm. However, there were no significant differences between 3 groups (P=0.73, r=0.03). In dynamic stereoacuity classified by the refractive error difference between two eyes, dynamic stereoacuity was $26.81{\pm}24.86$ sec of arc for the under 1 D, $41.45{\pm}24.18$ sec of arc for over 1 D, and there was no significant difference between two groups (P=0.15, r=0.15). Conclusions: Dynamic stereacuity by the H-D test in 20s adults showed that there was no significant differences between male and female, and PD and anisometropia did not have a significant impact upon the dynamic stereoacuity.

A study on evaluation of the image with washed-out artifact after applying scatter limitation correction algorithm in PET/CT exam (PET/CT 검사에서 냉소 인공물 발생 시 산란 제한 보정 알고리즘 적용에 따른 영상 평가)

  • Ko, Hyun-Soo;Ryu, Jae-kwang
    • The Korean Journal of Nuclear Medicine Technology
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    • v.22 no.1
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    • pp.55-66
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    • 2018
  • Purpose In PET/CT exam, washed-out artifact could occur due to severe motion of the patient and high specific activity, it results in lowering not only qualitative reading but also quantitative analysis. Scatter limitation correction by GE is an algorism to correct washed-out artifact and recover the images in PET scan. The purpose of this study is to measure the threshold of specific activity which can recovers to original uptake values on the image shown with washed-out artifact from phantom experiment and to compare the quantitative analysis of the clinical patient's data before and after correction. Materials and Methods PET and CT images were acquired in having no misalignment(D0) and in 1, 2, 3, 4 cm distance of misalignment(D1, D2, D3, D4) respectively, with 20 steps of each specific activity from 20 to 20,000 kBq/ml on $^{68}Ge$ cylinder phantom. Also, we measured the distance of misalignment of foley catheter line between CT and PET images, the specific activity which makes washed-out artifact, $SUV_{mean}$ of muscle in artifact slice and $SUV_{max}$ of lesion in artifact slice and $SUV_{max}$ of the other lesion out of artifact slice before and after correction respectively from 34 patients who underwent $^{18}F-FDG$ Fusion Whole Body PET/CT exam. SPSS 21 was used to analyze the difference in the SUV between before and after scatter limitation correction by paired t-test. Results In phantom experiment, $SUV_{mean}$ of $^{68}Ge$ cylinder decreased as specific activity of $^{18}F$ increased. $SUV_{mean}$ more and more decreased as the distance of misalignment between CT and PET more increased. On the other hand, the effect of correction increased as the distance more increased. From phantom experiments, there was no washed-out artifact below 50 kBq/ml and $SUV_{mean}$ was same from origin. On D0 and D1, $SUV_{mean}$ recovered to origin(0.95) below 120 kBq/ml when applying scatter limitation correction. On D2 and D3, $SUV_{mean}$ recovered to origin below 100 kBq/ml. On D4, $SUV_{mean}$ recovered to origin below 80 kBq/ml. From 34 clinical patient's data, the average distance of misalignment was 2.02 cm and the average specific activity which makes washed-out artifact was 490.15 kBq/ml. The average $SUV_{mean}$ of muscles and the average $SUV_{max}$ of lesions in artifact slice before and after the correction show a significant difference according to a paired t-test respectively(t=-13.805, p=0.000)(t=-2.851, p=0.012), but the average $SUV_{max}$ of lesions out of artifact slice show a no significant difference (t=-1.173, p=0.250). Conclusion Scatter limitation correction algorism by GE PET/CT scanner helps to correct washed-out artifact from motion of a patient or high specific activity and to recover the PET images. When we read the image occurred with washed-out artifact by measuring the distance of misalignment between CT and PET image, specific activity after applying scatter limitation algorism, we can analyze the images more accurately without repeating scan.