• Journal of Digital Convergence
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• 제15권3호
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• pp.287-294
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• 2017

This study attempted to develop a beacon scanner based ward monitoring service in order to respond to the new paradigm of medical environment which is trying to introduce ICT technology as medical service to track and manage the spread path of large infectious diseases such as MERS. The study also included beacon hardware development, firmware development for the beacon low-power bluetooth 4.0, and server and web-based dashboard UI development. Using these, we have developed a customized monitoring system that provides functions such as locating patients by location based service and monitoring based on web UI. It is possible to maximize the efficiency of offline hospital services and to value active infection control and patient safety by integrating online technology into the area where online technologies such as beacons are not properly integrated.

• Research in Plant Disease
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• 제12권1호
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• pp.20-24
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• 2006

Several pathogens associated with bulb rot of lilies in storage house were identified with respect to rot types. Rot patterns were grouped into four different types; brown rot of bottoms, brown rot of shoots, water-soaked rot and blue mold. Brown rot of bottoms was the highest in frequency with 72.5%, and brown rot of shoots the least with 23.0%. Dominant pathogens were differed with rot patterns, brown rot of bottoms by Fusarium oxysporum, blue mold and brown rot of shoots by Penicillium brevicompactum and P. fellutanum. In wound-inoculation tests, Penicillium and Fusarium isolates caused severe rot on the bulbs. Bulb disinfection before storage by captan showed the most prominent control value of 95.2% followed by thiophanate-methyl with 85.6%.

• Journal of Preventive Medicine and Public Health
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• 제43권5호
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• pp.396-402
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• 2010

Objectives: Self-reported anthropometric values, such as height and weight, are used to calculate body mass index (BMI) and assess the prevalence of obesity among adolescents. The aim of this study was to evaluate the validity of selfreported height, weight, and BMI of the Korea Youth Risk Behavior Web-based Survey questionnaire. Methods: A convenience sample of 137 middle school students and 242 high school students completed a selfadministered questionnaire in 2008. Body height and weight were directly measured after self-reported values were obtained from the questionnaire survey. Sensitivity, specificity, and kappa statistics were computed in order to evaluate the validity of the prevalence of obesity (BMI $\geq$ 95th percentile or $\geq$ $25;kg/$m^2$) based on self-reported data. Results: Self-reported weight and BMI tended to be underestimated. Self-reported height tended to be overestimated among middle school females and high school males. Obese adolescents tended to underestimate their weight and BMI and overestimate their height more than non-obese adolescents. The prevalence estimate of obesity based on selfreported data (10.6%) was lower than that based on directly measured data (15.3%). The estimated sensitivity of obesity based on self-reported data was 69.0% and the specificity was 100.0%. The value of kappa was 0.79 (95% confidence interval, 0.70 - 0.88). Conclusions: This study demonstrated that self-reported height and weight may lead to the underestimation of BMI and consequently the prevalence of obesity. These biases should be taken into account when self-reported data are used for monitoring the prevalence and trends of obesity among adolescents nationwide.

• The Plant Pathology Journal
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• 제31권1호
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• pp.25-32
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• 2015

Pseudomonas coronafaciens causes halo blight on oats and is a plant quarantine bacterium in many countries, including the Republic of Korea. Using of the certificated seed is important for control of the disease. Since effective detection method of P. coronafaciens is not available yet, PCR and TaqMan PCR assays for specific detection of P. coronafaciens were developed in this study. PCR primers were designed from the draft genome sequence of P. coronafaciens LMG 5060 which was obtained by the next-generation sequencing in this study. The PCR primer set Pc-12-F/Pc-12-R specifically amplified 498 bp from the 13 strains of P. coronafaciens isolated in the seven different countries (Canada, Japan, United Kingdom, Zimbabwe, Kenya, Germany, and New Zealand) and the nested primer set Pc-12-ne-F/Pc-12-ne-R specifically amplified 298 bp from those strains. The target-size PCR product was not amplified from the non-target bacteria with the PCR and nested primer sets. TaqMan PCR with Pc-12-ne-F/Pc-12-ne-R and a TaqMan probe, Pc-taqman, which were designed inside of the nested PCR amplicon, generated Ct values which in a dose-dependent manner to the amount of the target DNA and the Ct values of all the P. coronafaciens strains were above the threshold Ct value for positive detection. The TaqMan PCR generated positive Ct values from the seed extracts of the artificially inoculated oat seeds above 10 cfu/ml inoculation level. PCR and TaqMan PCR assays developed in this study will be useful tools to detect and identify the plant quarantine pathogen, P. coronafaciens.

• Journal of Life Science
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• 제24권9호
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• pp.1019-1024
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• 2014

Skeletal muscle atrophy can be defined as a decrease in or a disease of the muscle tissue, or as a disorder of the nerves that control the muscle, through injury or lack of use. This condition is associated with reactive oxygen species (ROS), resulting in various muscular disorders. Exposure to ROS induces muscle atrophy through several biological factors, such as SOD1 and HSP70. We found that cymbidium root extract reduced the $H_2O_2$-induced viability loss in C2C12 myoblasts and inhibited apoptosis. In addition, we showed that the cymbidium root extract increased the expression of HSP70 and decreased the expression of SOD1 in the $H_2O_2$-induced C2C12 myoblasts. These results suggest that cymbidium root extract might have therapeutic value in reducing ROS-induced muscle atrophy.

• Korean Journal of Clinical Laboratory Science
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• 제44권2호
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• pp.59-65
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• 2012

Previous studies have shown that modified Je-Ho-Tang (MJHT) has anti-platelet effects. Je-Ho-Tang (JHT), a Korean court beverage, is a traditional Korean herbal medicine that has been used for the treatment of a disease attended by great thirst, and for prevention of illness in hot summers. We made MJHT from JHT by excluding honey. The present study was performed to determine the acute oral toxicity of crude extract of MJHT in male and female ICR mice. We investigated the in vivo single dose acute toxicity of MJHT hot-water extraction. This test was orally administered once by gavage to 20 mice of each sex received doses of 0 (control group), 1250, 2500 and 5000 mg/kg body weight. Mortalities, clinical findings, autopsy findings and body weight changes were monitored daily for 14 days following the administration. We observed survival rates, general toxicities, changes of body weight, and autopsy. No significant lethality was observed after single oral administration of MJHT at the different dosages. Autopsies on the animals revealed no gross abnormalities. Therefore, the LD50 value of MJHT for ICR mice was estimated more than 5000 mg/kg by the oral route. These results suggest that no toxic dose level of MJHT in mice is considered to be more than 5000 mg/kg. Consequently, it was concluded that MJHT have no effect on acute toxicity and side effect in ICR mice.

• The Journal of Korean Society for School & Community Health Education
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• 제21권1호
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• pp.61-74
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• 2020

Objectives: This study aims to examine hypertension patients' quality of life by using the data of the 7^th Korea National Health and Nutrition Examination Survey (1^st year, 2016), identify the factors related to this, and utilize the results as basic data for intervention that can improve hypertension patients' quality of life. Methods: For the research subjects, this study extracted 1,531 patients who were diagnosed with hypertension by a doctor from the total sample of 8,150 participants of the 7^th Korea National Health and Nutrition Examination Survey, and selected 1,072 patients with no missing value in the variables to be analyzed as the final research subjects. The SPSS(version25.0) program was used for the analysis of the collected data. Then, this study used a backward elimination multiple regression analysis method that applied complex sample, to examine the factors related with the finally estimated quality of life. Results: The results of this study revealed that hypertension patients' quality of life was related with age, occupation, spouse, household income, weight gain, restriction of activity, subjected health status, perceived stress, and presence of comorbidity. The final model explained 37.0% of the variance (Wald F=30.012 p<.001). Conclusions: When an intervention program is implemented for the improvement of hypertension patients' quality of life in the future, it will be effective to construct the program according to age group, employment, marital status and household income. As for the program operation, patients should get help therefrom to control weight, facilitate activities and relieve their stress, and they should be also motivated to feel healthy. Furthermore, education should be offered so that they appropriately manage their underlying disease at an early stage.

• Korean Journal of Soil Science and Fertilizer
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• 제48권5호
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• pp.492-498
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• 2015

The long-term changes in the soil properties are closely related to the policy direction and the national program for the soil management. In this study, chemical properties of paddy soils in Jeonnam province were investigated at four-year interval since 1999 and the factors affecting change of chemical properties were analyzed in relation to the soil management policies. Chemical fertilizers supplied to Jeonnam province reduced by 57% in 2013 as compared with 1999, and the ratio of Jeonnam province to the national fertilizer supply gradually decreased to 14.1% in 2013 from 17.6% in 1999 due to national policies to reduce use of chemical fertilizers in the 2000s. In the chemical analysis of paddy soils in Jeonnam province, pH value tended to increase gradually within the optimal range. Available phosphate and exchangeable potassium content were always higher than the optimal range and showed no significant difference since 1999. Organic matter, exchangeable calcium and available silicate content were found to be lower than average content in the whole country as well optimal range for rice cultivation in 1999, but were higher than average content in the whole country and optimal range in 2011 because of faster rate of increase in Jeonnam province than the other region since the mid-2000s. The cause of increase in organic matter, exchangeable calcium and available silicate contents is considered to be the increased use of green manure crops and by-products fertilizer as an alternatives for conventional application of chemical fertilizers and soil amendment such as silicate fertilizer for agronomic control of the disease and insect pest in rice cultivation of environmentally-friendly agriculture.

• Journal of Veterinary Clinics
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• 제36권1호
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• pp.15-22
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• 2019

Highly pathogenic avian influenza (HPAI) is among the top infectious disease priorities in Korea and the leading cause of economic loss in relevant poultry industry. An understanding of the spatial epidemiology of HPAI outbreak is essential in assessing and managing the risk of the infection. Though previous studies have reported the majority of outbreaks occurred clustered in what are preferred to as densely populated poultry regions, especially in southwest coast of Korea, little is known about the spatial distribution of risk areas vulnerable to HPAI occurrence based on geographic information system (GIS). The main aim of the present study was to develop a GIS-based risk index model for defining potential high-risk areas of HPAI outbreaks and to explore spatial distribution in relative risk index for each 252 Si-Gun-Gu (administrative unit) in Korea. The risk index was derived incorporating seven GIS database associated with risk factors of HPAI in a standardized five-score scale. Scale 1 and 5 for each database represent the lowest and the highest risk of HPAI respectively. Our model showed that Jeollabuk-do, Chungcheongnam-do, Jeollanam-do and Chungcheongbuk-do regions will have the highest relative risk from HPAI. Areas with risk index value over 4.0 were Naju, Jeongeup, Anseong, Cheonan, Kochang, Iksan, Kyeongju and Kimje, indicating that Korea is at risk of HPAI introduction. Management and control of HPAI becomes difficult once the virus are established in domestic poultry populations; therefore, early detection and development of nationwide monitoring system through targeted surveillance of high-risk spots are priorities for preventing the future outbreaks.

• Hip & pelvis
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• 제30권4호
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• pp.219-225
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• 2018

Purpose: Ischiofemoral impingement (IFI)-primarily diagnosed by magnetic resonance imaging (MRI)-is an easily overlooked disease due to its low incidence. The purpose of this study was to evaluate the usefulness of false profile view as a screening test for IFI. Materials and Methods: Fifty-eight patients diagnosed with IFI between June 2013 and July 2017 were enrolled in this retrospective study. A control group (n=58) with matching propensity scores (age, gender, and body mass index) were also included. Ischiofemoral space (IFS) was measured as the shortest distance between the lateral cortex of the ischium and the medial cortex of lesser trochanter in weight bearing hip anteroposterior (AP) view and false profile view. MRI was used to measure IFS and quadratus femoris space (QFS). The receiver operating characteristics (ROC), area under the ROC curve (AUC) and cutoff point of the IFS were measured by false profile images, and the correlation between the IFS and QFS was analyzed using the MRI scans. Results: In the false profile view and hip AP view, patients with IFI had significantly decreased IFS (P<0.01). In the false profile view, ROC AUC (0.967) was higher than in the hip AP view (0.841). Cutoff value for differential diagnosis of IFI in the false profile view was 10.3 mm (sensitivity, 88.2%; specificity, 88.4%). IFS correlated with IFS (r=0.744) QFS (0.740) in MRI and IFS (0.621) in hip AP view (P<0.01). Conclusion: IFS on false profile view can be used as a screening tool for potential IFI.