• Journal of Life Science
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• v.24 no.5
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• pp.485-490
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• 2014

Poria cocas has been reported to be effective in skin whitening. However, the direct effect of P. cocas ethanol extracts (PCEE) on melanin synthesis has not been scientifically studied. To elucidate the direct effect of PCEE on melanogenesis, a 3,4-dihydroxyindole-2-carboxylic acid (DOPA) synthesis assay, tyrosinase activity assay, and Western blotting for melanogenic proteins, including tyrosinase, tyrosinase-related protein (TRP)-1, and TRP-2 were performed in mouse B16F1 cells. The results revealed that PGEE inhibited melanin production in a dose-dependent manner by blocking the synthesis of DOPA. Although the activation of tyrosinase was not affected, the expression levels of TRP-1 and TRP-2 were controlled. These results suggest that PCEE has a whitening effect, indicating that it may be a useful agent in the development of whitening cosmetics.

• The Journal of the Acoustical Society of Korea
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• v.19 no.1
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• pp.25-31
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• 2000

In this paper, we proposed an algorithm that used a direct method to set an initial value of Broydon-Fletcher-Goldfarb-Shanno(BFGS) method and, accordingly, conducted an experiment in optimal directivity synthesis of adaptive ultrasonic transducer by point source array. To certify the efficiency of this method, quasi-ideal beam with arbitrary beam width, rotating beam, and multi beam, all with the limited side lobe level -30dB, were chosen to check the problem of directivity synthesis that was formed by point source array in the second dimensional sound field. The numerical calculation results showed that the proposed method performed the directivity synthesis faster than the BFGS method did. In addition, the proposed method showed a good error correction for directivity synthesis, and did not demand the choice of initial value. Finally, it is also shown that the proposed method can be used for the adaptive control that was not possible with the direct method alone.

• Proceedings of the Korean Institute of Intelligent Systems Conference
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• 2004.10a
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• pp.211-216
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• 2004

In this thesis, we present the Takagi-Sugeno-Kang (TSK) fuzzy model based adaptive controller and adaptive identification for a general class of uncertain nonlinear dynamic systems. We use an estimated model for the unknown plant model and use this model for designing the controller. The hybrid adaptive control combined direct and indirect adaptive control based on TSK fuzzy model is constructed. The direct adaptive law can be showed by ignoring the identification errors and fails to achieve parameter convergence. Thus, we propose an TSK fuzzy model based hybrid adaptive (HA) law combined of the tracking error and the model ins error to adjust the parameters. Using a Lyapunov synthesis approach, the proposed hybrid adaptive control is proved. The hybrid adaptive law (HA) is better than the direct adaptive (DA) method without identifying the model ins error in terms of faster and improved tracking and parameter convergence. In order to show the applicability of the proposed method, it is applied to the inverted pendulum system and the performance is verified by some simulation results.

• Bulletin of the Korean Chemical Society
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• v.21 no.10
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• pp.959-968
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• 2000

Direct reaction of elemental silicon with a mixture of (dichloromethyl)silanes 1 $[Cl_3-nMenSiCHCl_2:$ n = 0 (a), n = 1(b), n = 2(c), n = 3(d)] and hydrogen chloride has been studied in the presence of copper catalyst using a stirred bed reactor equ ipped with a spiral band agitator at various temperatures from $240^{\circ}C$ to $340^{\circ}C.$ Tris(si-lyl) methanes with Si-H bonds, 3a-d $[Cl_3-nMenSiCH(SiHCl_2)_2]$, and 4a-d $[Cl_3-nMenSiCH(SiHCl_2)(SiCl_3)]$, were obtained as the major products and tris(silyl)methanes having no Si-H bond, 5a-d $[Cl_3-nMenSiCH(SiCl_3)_2]$, as the minor product along with byproducts of bis(chlorosilyl)methanes, derived from the reaction of silicon with chloromethylsilane formed by the decomposition of 1. In addition to those products, trichlorosilane and tetra-chlorosilane were produced by the reaction of elemental silicon with hydrogen chloride. The decomposition of 1 was suppressed and the production of polymeric carbosilanes reduced by adding hydrogen chloride to 1. Cad-mium was a good promoter for and the optimum temperature for this direct synthesis was $280^{\circ}C$.

• Proceedings of the Korean Magnestics Society Conference
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• 2003.12a
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• pp.211-211
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• 2003

• 한국전기화학회:학술대회논문집
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• 2002.07a
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• pp.175-178
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• 2002

• 한국전기화학회:학술대회논문집
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• 2003.07a
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• pp.225-228
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• 2003

• Bulletin of the Korean Chemical Society
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• v.24 no.7
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• pp.893-894
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• 2003

• Bulletin of the Korean Chemical Society
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• v.13 no.1
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• pp.96-98
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• 1992

• Bulletin of the Korean Chemical Society
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• v.14 no.3
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• pp.315-316
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• 1993