• Title/Summary/Keyword: dipping method

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Reduced Burst Release from ePTFE Grafts: A New Coating Method for Controlled Drug Release

  • Nam, Hye-Yeong;Kim, Dae-Joong;Lim, Hyun-Jung;Lee, Byung-Ha;Baek, In-Su;Park, Sang-Hun;Park, Jong-Sang
    • Bulletin of the Korean Chemical Society
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    • v.29 no.2
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    • pp.422-426
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    • 2008
  • Hemodialysis graft coated with paclitaxel prevents stenosis; however, large initial burst release of paclitaxel causes many negative effects such as drug toxicity and inefficient drug loss. Therefore we developed and tested a novel coating method, double dipping, to provide controlled and sustained release of paclitaxel locally. Expanded polytetrafluoroethylene (ePTFE) grafts were dipped twice into a solution of several different paclitaxel concentrations. In vitro release tests of the double dipping method showed that early burst release could be somewhat retarded and followed by sustained release for a long time. We observed the effect of paclitaxel coating by double dipping in porcine model of arterio-venous (AV) grafts between the common carotid artery and the external jugular vein. 12 weeks after constructing AV grafts, cross sections of the graft venous anastomosis were obtained and analyzed. Paclitaxel coated ePTFE grafts by double dipping were observed to prevent neointimal hyperplasia and therefore reduced stenosis of the arteriovenous hemodialysis grafts, especially at the graft venous anastomosis sites. Our results demonstrate that second dipping of ePTFE graft, which was already coated once with paclitaxel, washes off the drug on a surface of the graft and affects the ratio of paclitaxel on the surface to that of the inner space, possibly by diffusion: thus the early burst of drug can be somewhat reduced.

Effect of Natural Antimicrobial Agent Dipping and Antimicrobial Packaging Films on the Keeping Quality of Green Chilli Peppers (천연 항균제의 침지와 항균 포장필름이 풋고추의 저장성에 미치는 영향)

  • 정순경;조성환
    • Food Science and Preservation
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    • v.8 no.3
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    • pp.264-268
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    • 2001
  • Two antimicrobial extracts of Rheum palmatum L. and Coptis chinesis France root as well as grapefruit seed extract(GFSE) were applied to dipping treatment for green chilli peppers, which were then packed in low density polyethylene(LDPE) films incorporated with 1% antimicrobial extracts and stored 10$^{\circ}C$. Dipping and packaging treatments suppressed the growth of putrefactive microorganisms and the duly ratio of green chilli peppers. In addition, the loss ratio of ascorbic acid content and their weight during the storage was lower with treated green chilli peppers. Consequently, the combined method of dipping and packaging in antimicrobial agents turned out to be superior to dipping treatment or film-packaging in the view point of decay ratio and the keeping qualities of green chilli peppers.

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Effects of Blanching, Chemical Dipping, Freezing Methods and Storage Period on Quality of Frozen Mushrooms (Blanching, Chemical Dipping, 냉동방법 및 저장기간이 냉동 양송이의 품질에 미치는 영향)

  • Lee, Young-Chun;Lee, Kyung-Hae
    • Korean Journal of Food Science and Technology
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    • v.20 no.4
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    • pp.536-540
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    • 1988
  • Effects of blanching time, chemical dipping, freezing method and storage period on texture, color and yield of frozen whole and sliced mushrooms were investigated, and the results are summarized as follows; Frozen whole mushrooms blanched for 5min. had markedly tougher texture than mushrooms blanched for 1 or 2 minutes. As the storage time of frozen mushrooms increased from 3 to 6 months, shear press values increased very significantly. The texture of Freon frozen and plate frozen mushrooms was similar after 3 months storage. Blanching time did not affect texture of frozen sliced mushrooms significantly, but storage time did. The results of sensory evaluation for texture were in good agreement with shear press values. Chemical dipping methods were effective in maintaining desirable color of frozen whole and sliced mushrooms stored for 3 months. The yield of frozen whole mushrooms was significantly increased by shortening blanching time in combination with chemical dipping. Sliced mushrooms required at least 2 min. blanching, to avoid excessive breakage in mechanical slicing operation, for better yield.

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Abrasion of PET Fabrics by Using Microwave Energy (Microwave Energy를 이용한 PET 직물의 Abrasion)

  • Cho, In-Sul;Lee, Eun-Woo;Cho, Kyu-Min;Chang, Du-Sang
    • Journal of the Korean Society of Industry Convergence
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    • v.2 no.2
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    • pp.69-72
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    • 1999
  • The aim of this study is to enhance the abrasion of the hydrolyzed polyethylene terephthalate(PET) fabrics by using microwave energy. In other to achieve the aforementioned objectives, PET fabrics were hydrolyzed in NaOH solution by using abrasion method such as dipping, microwave-dipping, pad steam-dry, and pad microwave-dry, and then abrasion of the hydrolyzed PET fabrics was calculated and investigated. As a result obtained form this study, the abrasion of the hydrolyzed PET fabrics is directly proportional to hydrolyzed time and NaOH concentration. And also, microwave-dipping method and pad microwave-dry method showed remarkable abrasion effect than the others.

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A Study on the Plant Nutrients Impregnation Methods and Soil Covering Effects of Wood Chips (목재칩의 식물영양제 함침방법과 토양 피복효과에 관한 연구)

  • Yu Jin Hong;Dae Woo Choi;Kwon Woong Choi;Suejin Park;Seok Un Jo;Hee Jun Park
    • Journal of Korean Society of Industrial and Systems Engineering
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    • v.46 no.spc
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    • pp.31-38
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    • 2023
  • In this study, in order to develop a method to efficiently inject essential nutrients necessary for plant growth into wood chips, which are simply used as soil covering materials in the agriculture, landscaping and horticultural industries, the atmospheric pressure dipping method and the vacuum pressure impregnating method are used to improve the plant nutrients injectability and impregnation amount were comparatively analyzed. Nutrient ingredients and 8 major heavy metal contents of wood chips injected with nutrients were analyzed, and soil covering effects were examined by covering wood chips injected with nutrients on soil. Comparing the dipping method and the vacuum pressure impregnation method, it took about 48 hours or more to inject 1,500 g or more of the nutrient aqueous solution into 1 kg of wood chips in the dipping method, but the vacuum pressure impregnation method could be impregnated in about 5 minutes. Components of the impregnated nutrients were detected in proportion to the diluted concentration. As a result of covering the wood chips developed in this study on soil, they showed weakly acidic pH, and the heat insulation and moisturizing effects during the winter season were evaluated to be superior to those of uncovered soil. In the future, wood chips impregnated with nutrients are expected to contribute to the more efficient use of waste wood resources and the long-term supply of nutrients essential for plant growth, reducing excessive use of chemical fertilizers and reducing costs.

Effect of Microbial Control on Alfalfa Sprout Vegetable by Depending on Sanitization Method in Kindergarten Foodservice (유치원 급식으로 이용되는 알팔파 새싹채소의 소독방법에 따른 미생물제어 효과)

  • Woo, Suhee
    • Journal of The Korean Society of Integrative Medicine
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    • v.4 no.4
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    • pp.109-117
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    • 2016
  • Purpose : This study was designed to provide basic data of effective sanitization method of sprout vegetable for microbiological safety. Methods : Sanitization treatments were performed by dipping the sprout into chlorine and vinegar water. Microbial analysis were composed of the total plate count(TPC) and coliform group count(CGC). Result : Among chlorine water sanitization, the microbial reduction was largest in 100ppm chlorine water, and its TPC and coliform group count decreased to 6.01 log CFU/g and 5.06 log CFU/g. The effective dipping time in 100ppm chlorine water treatment was 5.97 log CFU/g and 5.91 log CFU/g for 30min and 60min, in which TPC were below the microbiological safety limits of 6.00 log CFU/g. Coliform group counts were decreased to 5.44, 5.46, 5.42 log CFU/g in the dipping the spouts for 30min, 60min and 90min. As a result of sanitizing alfalfa spout by vinegar water, a microbial counts tended to decrease with increasing concentration and the dipping time. The effective concentration of vinegar water was 2% for TPC(6.00 log CFU/g) and 1% for coliform group count(5.20 log CFU/g). With 1% vinegar water treatment, TPC became below the microbiological safety limits in all samples and in particular, the sample treated for 60min and 90min(4.93, 4.54 log CFU/g). While coliform group counts were decreased to 3.91 log CFU/g in the dipping the sprouts for 90min, those were still beyond the permitted limit. Conclusion : To secure the food safety of food service facilities including kindergarten feeding, it is considered that along with the systematic study of effective disinfection method for microbiological control at the preconditioning level of spout vegetable within the range of secured maleficence to human body, and the study regarding the measures to lower the initial microbiological pollution of spout vegetable.

Susceptibilities of German Cockroach, Blattella germanica to Insecticides According to Application Methods (바퀴에 대한 처리방법에 따른 살충제 감수성)

  • Han Jongbeen;Kim Gil-Hah
    • Korean journal of applied entomology
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    • v.43 no.3 s.136
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    • pp.241-247
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    • 2004
  • Susceptibility of Blattella germanica male adults to 61 commercial insecticides was evaluated by diet dipping method. Among them three insecticides of dichlorvos, fenitrothion, and fipronil showed over $90\%$ mortality. The insect was more susceptible to dichlorvos and fenitrothion in filter paper contact method than in diet dipping one, but fipronil was vice versa. Toxicities of the three chemicals were evaluated by application parts of the such as head, thorax, abdomen, and legs. Dichlorvos and fenitrothion were more toxic when applied to head, and flpronil was thorax. $LT_{50}$ values by diet dipping method showed that fenitrothion and fipronil acted more rapidly than boric acid and hydramethylnon. The values of the former two were 1.05 and 0.98 days, and those of the latter two were 3.92 and 2.26 days, respectively.

Susceptibilities of american cockroach, Periplaneta americana to insecticides according to application methods (이질바퀴에 대한 처리방법에 따른 살충제 감수성)

  • Han, Jong-Been;Bae, Jeong-Sook;Kim, Gil-Hah
    • The Korean Journal of Pesticide Science
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    • v.8 no.3
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    • pp.210-219
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    • 2004
  • Susceptibility of Periplaneta americana male adults to 61 commercial insecticides was evaluated by diet dipping method. Among them eight insecticides of dichlorvos, benfuracarb, cypermethrin, deltamethrin, fenpropathrin, $\zeta$-cypermethrin, $\lambda$-cyhalothrin and fipronil showed 100% mortality. The insect was more susceptible to dichlorvos and fenpropathrin in filter paper contact method than in diet dipping one, but benfuracarb was vice versa. Toxicities of the seven chemicals were evaluated by application parts of the such as head, thorax, abdomen, and legs. Dichlorvos, benfuracarb and $\lambda$-cyhalothrin were more toxic when applied to head, and deltamethrin, fenpropathrin and cypermethrin were abdomen. $LT_{50}$ values by diet dipping method showed that dichlorvos, benfuracarb and $\lambda$-cyhalothrin acted more rapidly than boric acid and hydramethylnon. The values of the former three were 0.10, 0.29 and 0.12 days, and those of the latter two were 6.2 and 4.8 days, respectively.

중공사막 PLASMA 고분자 코팅에 관한 연구 - 고분자층 두께분포를 중심으로 -

  • 손우익;구자경;김병식
    • Proceedings of the Membrane Society of Korea Conference
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    • 1997.10a
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    • pp.141-142
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    • 1997
  • 1. 서론 : 중공사막은 제조과정인 wet spinning의 과정에서 defect가 형성될 수 있어 분리선택도에 큰 영향을 미친다. 이러한 defect의 처리방법으로는 dipping method등의 방법이 현재 널리 쓰이고 있다. dipping method는 제조된 중공사막을 PDMS등의 고분자 용액 속으로 통과시켜 결과적으로 중공사막 표면에 얇은 고분자막이 형성되도록 하는 방법이다. 그러나 이러한 방법으로 중공사막을 처리할 경우 고분자 용액이 pore내로 침입하거나 중력으로 인하여 용액의 아래쪽으로 몰려 하반부의 두께가 두꺼워진다는 단점이 있다.(생략)

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Selection of Low Toxic Pesticides and Residual Toxicity to Cotesia glomerata (배추나비고치벌 (Cotesia glomerata)에 대한 저독성 약제 및 잔류독성)

  • Choi, Byeong-Ryeol;Lee, Si-Woo;Park, Hyung-Man
    • Korean journal of applied entomology
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    • v.46 no.2
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    • pp.251-259
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    • 2007
  • For the development of integrated pest management system by harmonizing biological and chemical control, some experiments wee carried out to select low toxic pesticides against natural enemies. and their residual toxicity were evaluated. Leaf dipping method, body dipping method, and diet treatment method were set up for the toxicity evaluation against Cotesia glomerata adults. We had tested 46 different pesticides (31 insecticides, 11 fungicides, 4 herbicides) at recommending concentration commonly used to control diamond back moth, disease and up-land weeds in chinese cabbage field. Twenty three insecticides, eleven fungicides, and four herbicides were shown to be low toxic to C. glomerata adults in the treatment of body dipping. After insecticide spraying at recommending dose on the chinese cabbage, we examined residual effect of insecticides by introducing natural enemies on different days. Safety interval for the introduction of C. glomerata adults was established according to the residual toxicity of pesticides. Safe insecticides for the introduction of C. glomerata adults at one day after treatment (DAT) were thiacloprid, acephate, chlorfenapyr, clothianidin and at 3 DAT were imidacloprid, deltamethrin, thiamethoxam, dimethylvinphos, emamectin benzoate.