• Clinical and Experimental Pediatrics
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• v.49 no.4
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• pp.439-445
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• 2006

Purpose : ${\alpha}$-Galactosylceramide (${\alpha}$-GalCer)-stimulated human $V{\alpha}24$ natural killer T (NKT) cells exert antitumor activity against some leukemia in a CD1d dependent and TCR-mediated manner, but could not kill CD1d - negative neuroblastoma (NB) cells. There are few reports about the direct antitumor effect of highly secreted cytokines by these cells on activation. In this study, using a cell-free supernatant (SPN) collected from plate bound hCD1d/${\alpha}$ GalCer tetramers-stimulated NKT cells, we examined whether they could be helpful in the immunotherapeutic treatment of NB. Methods : Cells were cultured in IMDM. The cytokines produced by NKT cells were measured with Cytometric Bead Array (CBA) analysis. Cell viability was evaluated by calcein-AM fluorescence with digital image microscopy scanning (DIMSCAN). The percentage of specific apoptosis was calculated by flow cytometric detection of apoptosis using annexin V and 7-AAD. Results : The activated NKT cells secreted high levels of IL-2, INF-${\gamma}$, TNF-${\alpha}$. The SPN was significantly cytotoxic against four out of eight tested NB cell lines, through mainly apoptosis as evidenced by annexin-V staining and inhibition with the pretreatment of pancaspase blocker. This apoptosis was significantly inhibited when anti-TNF-${\alpha}$ and anti-IFN-${\gamma}$ neutralizing mAbs were used separately and it was completely abolished when the two mAbs were combined. Conclusion : IFN-${\gamma}$ and TNF-${\alpha}$ produced by NKT cells could exert synergistically direct antitumor activity through apoptosis on some NB cell lines.

• Cartoon and Animation Studies
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• s.35
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• pp.329-346
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• 2014

Art is the product from the combination of politics, economy, and social and cultural aspects. Recent development of digital media has affected on the expansion of visual expression in art. Digital media allow artists to use sound and physical interaction as well as image as an plastic element for making a work of art. Also, digital media help artists create an interactive, synaesthetic and visual perceptive environment by combining viewers' physical interaction with the reconstruction of image, sound, light, and among other plastic elements. This research was focused on the analysis of the relationship between images in art work and the viewer and data visualization using sound from the perspective of visual perception. This research also aimed to develop an interactive art by visualizing physical data with sound generating from outer stimulus or the viewer. Physical data generating from outer sound can be analyzed in various aspects. For example, Sound data can be analyzed and sampled within pitch, volume, frequency, and etc. This researcher implemented a new form of media art through the visual experiment of LED light triggered by sound frequency generating from viewers' voice or outer physical stimulus. Also, this researcher explored the possibility of various visual image expression generating from the viewer's reaction to illusionary characteristics of light(LED), which can be transformed within external physical data in real time. As the result, this researcher used a motif from Piet Mondrian's Broadway Boogie Woogie in order to implement a visual perceptive interactive work reacting with sound. Mondrian tried to approach at the essence of visual object by eliminating unnecessary representation elements and simplifying them in painting and making them into abstraction consisting of color, vertical and horizontal lines. This researcher utilized Modrian's simplified visual composition as a representation metaphor in oder to transform external sound stimulus into the element of light(LED), and implemented an environment inducing viewers' participation, which is a dynamic composition maximizing a synaesthetic expression, differing from Modrian's static composition.

• Journal of the Institute of Electronics Engineers of Korea TC
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• v.46 no.12
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• pp.6-13
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• 2009

For X-band phased array systems, a power amplifier, a 6-bit phase shifter, a 6-bit digital attenuator, and a SPDT transmit/receive (T/R) switch are fabricated and measured. All circuits are demonstrated by using CMOS 0.18 um technology. The power amplifier has 2-stage differential and cascade structures. It provides 1-dB gain-compressed output power ($P_{1dB}$) of 20 dBm and power-added-efficiency (PAE) of 19 % at 8-11 GHz frequencies. The 6-bit phase shifter utilizes embedded switched filter structure which consists of nMOS transistors as a switch and meandered microstrip lines for desired inductances. It has $360^{\circ}$ phase-control range and $5.6^{\circ}$ phase resolution. At 8-11 GHz frequencies, it has RMS phase and amplitude errors are below $5^{\circ}$ and 0.8 dB, and insertion loss of $-15.7\;{\pm}\;1,1\;dB$. The 6-bit digital attenuator is comprised of embedded switched Pi-and T-type attenuators resistive networks and nMOS switches and employes compensation circuits for low insertion phase variation. It has max. attenuation of 31.5 dB and 0.5 dB amplitude resolution. Its RMS amplitude and phase errors are below 0.4 dB and $2^{\circ}$ at 8-11 GHz frequencies, and insertion loss is $-10.5\;{\pm}\;0.8\;dB$. The SPDT T/R switch has series and shunt transistor pairs on transmit and receive path, and only one inductance to reduce chip area. It shows insertion loss of -1.5 dB, return loss below -15 dB, and isolation about -30 dB. The fabricated chip areas are $1.28\;mm^2$, $1.9mm^2$, $0.34\;mm^2$, $0.02mm^2$, respectively.

• Fiber Technology and Industry
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• v.2 no.4
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• pp.490-508
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• 1998

One of the latest fields of research in the area of output devices is tactual display devices [13,31]. These tactual or haptic devices allow the user to receive haptic feedback output from a variety of sources. This allows the user to actually feel virtual objects and manipulate them by touch. This is an emerging technology and will be instrumental in enhancing the realism of wearable augmented environments for certain applications. Tactual displays have previously been used for scientific visualization in virtual environments by chemists and engineers to improve perception and understanding of force fields and of world models populated with the impenetrable. In addition to tactual displays, the use of wearable audio displays that allow sound to be spatialized are being developed. With wearable computers, designers will soon be able to pair spatialized sound to virtual representations of objects when appropriate to make the wearable computer experience even more realistic to the user. Furthermore, as the number and complexity of wearable computing applications continues to grow, there will be increasing needs for systems that are faster, lighter, and have higher resolution displays. Better networking technology will also need to be developed to allow all users of wearable computers to have high bandwidth connections for real time information gathering and collaboration. In addition to the technology advances that make users need to wear computers in everyday life, there is also the desire to have users want to wear their computers. In order to do this, wearable computing needs to be unobtrusive and socially acceptable. By making wearables smaller and lighter, or actually embedding them in clothing, users can conceal them easily and wear them comfortably. The military is currently working on the development of the Personal Information Carrier (PIC) or digital dog tag. The PIC is a small electronic storage device containing medical information about the wearer. While old military dog tags contained only 5 lines of information, the digital tags may contain volumes of multi-media information including medical history, X-rays, and cardiograms. Using hand held devices in the field, medics would be able to call this information up in real time for better treatment. A fully functional transmittable device is still years off, but this technology once developed in the military, could be adapted tp civilian users and provide ant information, medical or otherwise, in a portable, not obstructive, and fashionable way. Another future device that could increase safety and well being of its users is the nose on-a-chip developed by the Oak Ridge National Lab in Tennessee. This tiny digital silicon chip about the size of a dime, is capable of 'smelling' natural gas leaks in stoves, heaters, and other appliances. It can also detect dangerous levels of carbon monoxide. This device can also be configured to notify the fire department when a leak is detected. This nose chip should be commercially available within 2 years, and is inexpensive, requires low power, and is very sensitive. Along with gas detection capabilities, this device may someday also be configured to detect smoke and other harmful gases. By embedding this chip into workers uniforms, name tags, etc., this could be a lifesaving computational accessory. In addition to the future safety technology soon to be available as accessories are devices that are for entertainment and security. The LCI computer group is developing a Smartpen, that electronically verifies a user's signature. With the increase in credit card use and the rise in forgeries, is the need for commercial industries to constantly verify signatures. This Smartpen writes like a normal pen but uses sensors to detect the motion of the pen as the user signs their name to authenticate the signature. This computational accessory should be available in 1999, and would bring increased peace of mind to consumers and vendors alike. In the entertainment domain, Panasonic is creating the first portable hand-held DVD player. This device weight less than 3 pounds and has a screen about 6' across. The color LCD has the same 16:9 aspect ratio of a cinema screen and supports a high resolution of 280,000 pixels and stereo sound. The player can play standard DVD movies and has a hour battery life for mobile use. To summarize, in this paper we presented concepts related to the design and use of wearable computers with extensions to smart spaces. For some time, researchers in telerobotics have used computer graphics to enhance remote scenes. Recent advances in augmented reality displays make it possible to enhance the user's local environment with 'information'. As shown in this paper, there are many application areas for this technology such as medicine, manufacturing, training, and recreation. Wearable computers allow a much closer association of information with the user. By embedding sensors in the wearable to allow it to see what the user sees, hear what the user hears, sense the user's physical state, and analyze what the user is typing, an intelligent agent may be able to analyze what the user is doing and try to predict the resources he will need next or in the near future. Using this information, the agent may download files, reserve communications bandwidth, post reminders, or automatically send updates to colleagues to help facilitate the user's daily interactions. This intelligent wearable computer would be able to act as a personal assistant, who is always around, knows the user's personal preferences and tastes, and tries to streamline interactions with the rest of the world.

• Information Systems Review
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• v.14 no.1
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• pp.67-84
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• 2012

Recent increases in uncertainty and speed of market change are driving the adoption of new intelligent mobile office systems. Organizational information systems paradigm suggests that a right match between organizational characteristics and the use of technology is critical in producing desired results. Following such perspective this study developed the mobile office system case of Seoul Metropolitan Railway Transit(SMRT) in Korea. SMRT developed the mobile task-supporting environment that help the management of subway lines real-time without the restriction of time and space. They named the system as ST&F(SMRT Talk and Flash). They decided to develop the application systems in-houses they did not want to be overly dependent on external services in future changes and developments of the system. The new practice reduced the time for moving back and forth to 10% of their working time from previous 20%. The time used for paper works and administration chore also reduce to 10% of their working time from previous 30% on the average. The employees could use 80% of their time to concentrate on the completion of assigned task. The effects of this improvement resulted in the heightened efficiency of the use of human resources and the heightened level of railway safety. The case of SMRT shows that the mobile office system can be applied and extended to various business areas such as facility management and maintenance beyond such typical uses as sales and marketing support. Also, The result of case study will be a useful guideline on the construction and using of mobile office system.

• Journal of the Korean Association of Geographic Information Studies
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• v.14 no.1
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• pp.84-93
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• 2011

Levee line mapping is critical to the protection of environments in river zones, the prevention of river flood and the development of river zones. Use of the remote sensing data such as LiDAR and aerial orthoimage is efficient for river mapping due to their accessibility and higher accuracy in horizontal and vertical direction. Airborne laser scanning (LiDAR) has been used for river zone mapping due to its ability to penetrate shallow water and its high vertical accuracy. Use of image source is also efficient for extraction of features by analysis of its image source. Therefore, aerial orthoimage also have been used for river zone mapping tasks due to its image source and its higher accuracy in horizontal direction. Due to these advantages, in this paper, research on three dimensional levee line mapping is implemented using LiDAR and aerial orthoimage separately. Accuracy measurement is implemented for both extracted lines generated by each data using the ground truths and statistical comparison is implemented between two measurement results. Statistical results show that the generated 3D levee line using LiDAR data has higher accuracy than the generated 3D levee line using aerial orthoimage in horizontal direction and vertical direction.

• The Journal of Korean Institute of Electromagnetic Engineering and Science
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• v.20 no.10
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• pp.1031-1041
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• 2009

A small microstrip monopole antenna for macro-micro frequency tuning over multiple bands is presented. The meander-shape antenna is fabricated on a conventional printed circuit board(FR-4, $\varepsilon_r=4.4$ and tan $\delta=0.02$). The antenna operates over WiBro(2.3~2.4 GHz) and WLAN a/b(2.4~2.5 GHz/5.15~5.35 GHz) service bands with an essentially constant antenna gain within each service band. Two diodes, a PIN diode and a varactor, are embedded into the antenna for frequency reconfiguration. The PIN diode is used for frequency switching(macro-tuning) between 2 GHz and 5 GHz bands while the varactor is used for frequency tuning(micro-tuning) within the service bands, 2.3~2.5 GHz and 5.15~5.35 GHz. Unwanted resonances between the two frequency bands(2 GHz and 5 GHz) are suppressed by filling up the gaps between the meander lines. The antenna gain is essentially constant and higher than 2 dBi within each service band. The measured performance of the proposed antenna system suggests the macro-micro frequency tuning techniques be useful in reconfigurable wireless communication systems.

• Journal of the Korean Society of Surveying, Geodesy, Photogrammetry and Cartography
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• v.22 no.1
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• pp.21-27
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• 2004

It will be a real good news fer the people who were lost their hometown by the construction of a large dam to be restored to the farmer state. Focused on Cheung-pyung around where most part were submerged by the Chungju large Dam founded in eurly 1980s, It used remote sensing image restoration Technique in this study in order to restore topographical features before the flood with stereo effects. We gathered comparatively good satellite photos and remotely sensed digital images, then its made a new fusion image from these various satellite images and the topographical map which had been made before the water filled by the DAM. This task was putting together two kinds of different timed images. And then, we generated DEM including the outskirts of that area as matching current contour lines with the map. That could be a perfect 3D image of test areas around before when it had been water filled by making perspective images from all directions included north, south, east and west, fer showing there in 3 dimensions. Also, for close range visiting made of flying simulation can bring to experience their real space at that time. As a result of this experimental task, it made of new fusion images and 3-D perspective images and simulation live images by remotely sensed photos and images, old paper maps about vanished submerged Dam areas and gained of possibility 3-D terrain image restoration about submerged area by large Dam construction.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.18 no.8
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• pp.355-360
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• 2017

Recently, with the development of autonomous vehicle technology, the importance of precise road maps is increasing. A precise road map is a digital map with lane information, regulations, safety information, and various road facilities. Conventional precise road maps have been tested and developed based on the mobile mapping system (MMS). But they have not been activated due to high introduction costs. However, in the case of unmanned aerial vehicles (UAVs), the application field is continuously increasing. This study tries to extract information through classification of high-resolution UAV images for autonomous driving. Autonomous vehicle test roads were selected as study sites, and high-resolution orthoimages were produced using UAVs. In addition, the utilization of high-resolution orthoimages has been proposed by effectively extracting data for precise road map construction, such as road lines, guards, and machines through image classification. If additional experimentation and verification are performed, the field of UAV image use will be expanded, providing the data to automobile manufacturers and related public and private organizations, and venture companies will contribute to the development of domestic autonomous vehicle technology.

• Journal of the Institute of Electronics Engineers of Korea SP
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• v.42 no.3 s.303
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• pp.107-114
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• 2005

Edge enhanced image is needed for processing images for special purpose such as a circuit diagram or a design composed of lines. Error diffusion halftoning, among digital halftoning methods to represent a continuous grayscale image for the binary output device such as printers, facsimiles, LCD televisions and etc. also makes edges of objects blurred. This paper proposes the method to enhance the edge of a binary image for the binary output device as well as a circuit diagram or a design. Based on that the human eyes perceive the local average luminance rather than the pixel's luminance itself, the proposed system uses a local activitymeasure (LAM), which is the difference between a pixel luminance and the average of its $3{\times}3$ neighborhood pixels' luminances weighted according to the spatial positioning. The system also usesinformation of edge enhancement(IEE), which is computed from the LAM multiplied by the average luminance. The IEE is added to the quantizer's input pixel and feeds into the halftoning quantizer. The quantizer produces the halftone image having the enhanced edge. The simulation results show that the proposed method produces more fine halftoning images than conventional methods due to the enhanced edges. Also the performance of the proposed method is compared with that of the conventional method by measuring the edge correlation and the local average accordance over a range of viewing distances.