• Biotechnology and Bioprocess Engineering:BBE
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• v.7 no.4
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• pp.225-230
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• 2002

Experiments on deactivation kinetics of immobilized lipase enzyme from Candida cyl-indracea were performed in stirred bath reactor using rice bran oil as the substrate and temperature as the deactivation parameter. The data were fitted In first order deactivation model. The effect of temperature on deactivation rate was represented by Arrhenius equation. Theoretical equations were developed based on pseudo-steady state approximation and Michaelis -Menten rate expression to predict the time course of conversion due to enzyme deactivation and apparent half-life of the immobilized enzyme activity in PFR and CSTH under constant feed rate polity for no diffusion limitation and diffusion limitation of first order. Stability of enzyme in these continuous reactors was predicted and factors affecting the stability were analyzed.

• Korean Management Science Review
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• v.13 no.1
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• pp.71-95
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• 1996

Many researchers have studied the theme on CASE technology. However, there are no many researches which lightened the diffusion of CASE technology and organizational change. The purpose of this study is to investigate the factors that influence on the diffusion of CASE technology and the way how IS organization changes as a result of the diffusion. We exploited a case study research as a methodology. We selected five software development firms which possessed the leading IS technology abilities as the case companies. We realized that the diffusion of CASE technology proceeded under the three context variables - managerial context of information systems, the intent and behavior of key players and implementation strategy of organization - to enhance the performance of information systems. The contribution of this study is to clarify the change of IS organization as a result of CASE technology diffusion. This study has the limitation that tried to analyze the organizational change only in a direction.

• IE interfaces
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• v.23 no.4
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• pp.337-348
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• 2010

The Bass model is the most widely used model in research of new product diffusion because it presents a nice explanation on the diffusion process of new products. However, it has a limitation that its performance of fitness is lower as the available data become less and also, the diffusion curve is bell-shape and so, it can not represent the various diffusion patterns. Recently, a two-pieces Bass model is developed and applied to analyze diffusion of 10 products. The results are encouraging in terms of fitness. However, diffusion pattern is not dealt with in the paper. In this paper, analysis of diffusion pattern is in depth addressed in two-pieces Bass model. It is shown that the diffusion curves are divided into 3 types with respect to the peak adoption rate and each type is divided into 2 types further. Takeoff time of a diffusion process is analyzed by using the inflection point and regime-change time where it represents the point that imitation and innovation parameters change. Empirical studies for 68 products(28 domestic products and 40 USA products) are performed to analyze the diffusion pattern. Findings are that diffusion patterns of all products except 1 USA product show type I and regime-change time becomes shorter as the introduction time of the product is later in domestic products and regime-change time can be regarded as a takeoff time in 47% of total 68 products.

• Transactions of the Korean Society for Noise and Vibration Engineering
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• v.26 no.3
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• pp.315-322
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• 2016

Room acoustic properties of coupled rooms connected by an aperture has been analyzed using statistical acoustic model based on the diffused sound field assumption, which has limitation in dealing with the parameters such an room geometries and non uniform absorptivity of the boundary surfaces. In order to overcome these difficulties the acoustic diffusion model has been introduced, by which distribution of the acoustic energy density can be analyzed for various shapes and wall absorptivity. In this study acoustic properties of coupled rooms connected by an aperture(e.g. door) is analyzed using acoustic diffusion equation, which is solved numerically. The mean energy densities of two rooms obtained by the diffusion model are compared with those from the statistical model. The results show good agreement for various coupling aperture sizes and absorption coefficients. For a limiting case when the partition wall is substituted by an aperture and the two rooms eventually forms a single room, results of coupled room analysis using diffusion model show good agreement with those of a single room.

• Investigative Magnetic Resonance Imaging
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• v.23 no.1
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• pp.26-33
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• 2019

Purpose: Diffusion tensor imaging (DTI) data must be analyzed by an analyzer after data processing. Hence, the analyzed data of DTI might depend on the analyzer, making it a major limitation. This paper reviewed previous DTI studies reporting the repeatability and reproducibility of data from the corticospinal tract (CST), one of the most actively researched neural tracts on this topic. Materials and Methods: Relevant studies published between January 1990 and December 2018 were identified by searching PubMed, Google Scholar, and MEDLINE electronic databases using the following keywords: DTI, diffusion tensor tractography, reliability, repeatability, reproducibility, and CST. As a result, 15 studies were selected. Results: Measurements of the CSTs using region of interest methods on 2-dimensional DTI images generally showed excellent repeatability and reproducibility of more than 0.8 but high variability (0.29 to 1.00) between studies. In contrast, measurements of the CST using the 3-dimensional DTT method not only revealed excellent repeatability and reproducibility of more than 0.9 but also low variability (repeatability, 0.88 to 1.00; reproducibility, 0.82 to 0.99) between studies. Conclusion: Both 2-dimensional DTI and 3-dimensional DTT methods appeared to be reliable for measuring the CST but the 3-dimensional DTT method appeared to be more reliable.

• The Journal of the Korea Contents Association
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• v.7 no.10
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• pp.202-210
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• 2007

Factor analysis, an important research method, has been conducted as a pre-analysis of empirical researches. Sometimes, the researchers expect more information than factor analysis' limitation as well. Therefore, I suggest a method to overcome this problem. This study presents a combined research method which allow to solve the limitation of the factor analysis in social science. The combined research method consist of factor analysis, AHP(analytic hierarchy process) analysis, diffusion theory and system dynamics, which is able to explain causalities.

• The Journal of the Korea Contents Association
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• v.12 no.9
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• pp.348-356
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• 2012

This study is identifying early takeoff phenomenon in relational network like SNS and investigates influence of innovator or hub at early takeoff and diffusion size at takeoff point. The major finding of this study are as follows. First, multinominal-logit analysis conducted to explore the impact of innovator and hub at early stage of information diffusion and early takeoff. Hub in early stage of information diffusion impact early takeoff. Second, our study shows that innovator and hub at early stage of information diffusion impact diffusion size at takeoff point. Third, hub is more impact early takeoff and diffusion size at takeoff point then innovator. This study provides implication for professionals by confirming hub's influence in study of successful information diffusion by early takeoff. The limitation and future direction are discussed.

• CRM연구
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• v.1 no.1
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• pp.49-69
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• 2006

Previous studies, Technology Acceptance Model (TAM) and Post Acceptance Model (PAM) have a little limitation in time series analysis. To solve this limitation, we used system dynamics as research methodology and designed simulation model based on TAM and PAM. Moreover, we designed new simulation model which can analyize time series data in customers' demand change from initial acceptance to post acceptance. This study targeted domestic mobile phone market. The simulation results showed that diffusion graph was similar to real data. That means we validated our simulation model. Since the simulation model offers the graph of customer's demand change by time, so it can be useful as a leaning tool. Therefore, we think this study helps IT companies use the model for forecasting of market demand.

• Journal of the Korean Wood Science and Technology
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• v.40 no.5
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• pp.352-362
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• 2012

Mass transfer behavior in wood was estimated through its microscopic structure. The diffusion coefficients which were decided by theoretical equations are influenced by different anatomical properties of wood. From the experiment, the moisture flux was linear to the square root of time. The diffusion coefficients had a regular tendency during the time elapse. During the modeling, it is necessary to understand the limitation of parameters and consider the particular situation to be simulated. In hardwood, because the apertures were not considered, tangential mass transfer simulation was totally different from experiment. As a result, a hardwood model design should consider the apertures which are even on the fiber walls.

• Bulletin of the Korean Chemical Society
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• v.25 no.5
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• pp.737-741
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• 2004

We presents new results for transport properties of dumbbell fluids by equilibrium molecular dynamics (EMD) simulations using Green-Kubo and Einstein formulas. It is evident that the interaction between dumbbell molecules is less attractive than that between spherical molecules which leads to higher diffusion and to lower friction. The calculated viscosity, however, is almost independent on the molecular elongation within statistical error bar, which is contradicted to the Stokes' law. The calculated thermal conductivity increases and then decreases as molecular elongation increases. These results of viscosity and thermal conductivity for dumbbell molecules by EMD simulations are inconsistent with the earlier results of those by non-equilibrium molecular dynamics (NEMD) simulations. The possible limitation of the Green-Kubo and Einstein formulas with regard to the calculations of viscosity and thermal conductivity for molecular fluids such as the missing rotational degree of freedom is pointed out.