• Tuberculosis and Respiratory Diseases
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• 제62권6호
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• pp.486-491
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• 2007

배 경: 결핵성흉막염환자에서 흉수 내 아데노신 탈아민효소(ADA) 활성도와 CT에서 흉막의 조영증강 양상과의 연관성에 대해 알아보고자 하였다.방 법: 2002년 2월부터 2006년 10월까지 결핵성흉막염으로 진단되고 동시에 조영증강 CT를 시행한 44명을 후향적으로 분석하였다. 결핵성흉막염의 진단은 흉수 내 ADA활성도와 추적검사(24/44), 객담도말이나 배양(16/44), 흉막배양(3/44), 그리고 흉막조직검사(1/44)로 얻었다. 흉수 내 ADA활성도 값이 40-70 U/L인 환자는 I군(12명)으로, 71 U/L이상인 환자는 II군(32명)으로 분류하였다. CT에서 흉막의 조영증강 유무, 최대 흉막두께, 조영증강의 양상을 분석하였다. 흉막의 조영증강 양상은 미만성(diffuse)인지 국소성(focal)인지, 매끈(smooth)한지 불규칙(irregular)한지, 혹은 단절성(Interrupted)인지 연속적(continuous)인지로 나누어 분석하였다. I군과 II군 사이에 CT 소견의 차이가 있는지를 분석하였다. 통계적 방법은 T 검정, 카이제곱검정 그리고 비율의 검정을 사용하였다.결 과: 44명 모두 CT에서 흉막의 조영증강이 관찰되었다. I군과 II군의 흉막의 최대 두께는 각 $1.83{\pm}1.03mm$ (1-4 mm), $3.63{\pm}1.78mm$ (18 mm)이어서 유의한 차이가 있었다(p= 0.0002). 특히, I군의 흉막비후의 두께는 모든 예에서 4 mm 이하이었고, 5 mm 이상으로 흉막이 두꺼워진 경우는 II군에서만 31.3%(10/32) 있었다. I군은 미만성이고 단절성인 흉막비후(diffuse, interrupted pleural enhancement)를 보인 예가 91.7% (11/12), 미만성이고 연속적인 흉막비후를 보인 예가 8.3%(1/12)있었고, II군은 각각 62.5%(20/32), 37.5% (12/32) 있었다. I군보다 미만성이고 연속적인 흉막비후(diffuse and continuous pleural enhancement)를 보인 예가 II군에서 많았으나 통계적 유의성은 없었다(p=0.0748).

• Tuberculosis and Respiratory Diseases
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• 제76권1호
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• pp.42-45
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• 2014

An immunoglobulin G4 (IgG4)-related disease is a recently emerging entity, and a few cases of IgG4-related disease in lung and pleura have been reported. Herein, we report the case of a 74-year-old man with IgG4-related disease of lung and pleura, clinically suspicious of malignant mesothelioma. Chest computed tomography showed diffuse nodular pleural thickening, and microscopic finding disclosed diffuse thickening of visceral pleura with infiltrations of many lymphoplasma cells with increased number of IgG4-positive plasma cells and a few multinucleated giant cells. It is important for pathologists and clinicians to recognize this rare entity and its histologic finding, because it can be confused with malignant tumors on the radiologic examination although it can be treated with steroid therapy.

• Journal of Chest Surgery
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• 제24권6호
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• pp.595-604
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• 1991

Pleural mesothelioma is usually divided into two forms of localized and diffuse type. Localized pleural fibrous mesothelioma is uncommon mesodermal neoplasm, which may occurs in both sexes and at the age of 50 years. This type of mesothelioma is usually asymptomatic and detected on routine chest X-ray and made fibrous tissue and shows of collagen fibers microscopically. Most localized fibrous mesothelioma arises from the visceral pleura and is well encapsulated and pedunculated mass. CT findings included well delineated, often lobulated, non-calcified soft tissue masses in close relation to a pleural space, associated pleural thickening, and absence of chest wall invasion and a peripheral or fissure location. Three cases of localized pleural fibrous mesothelioma diagnosed by resectional surgery were reported with the review of literature.

• Safety and Health at Work
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• 제5권4호
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• pp.234-237
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• 2014

Background: Inhalation of asbestos fibers can lead to adverse health effects on the lungs. This study describes lung function profiles among individuals with nonmalignant asbestos-related disorders (ARDs). Methods: The study population was from the Workers' Compensation (Dust Diseases) Board of New South Wales, Sydney, Australia. Lung function measurements were conducted in males with asbestosis (n = 26), diffuse pleural thickening (DPT; n = 129), asbestosis and DPT (n = 14), pleural plaques only (n = 160) and also apparently healthy individuals with a history of asbestos exposure (n = 248). Standardized spirometric and single-breath diffusing capacity for carbon monoxide ($DL_{CO}$) measurements were used. Results: Mean age [standard deviation (SD)] was 66.7 (10.3) years for all participants. Current and ex-smokers among all participants comprised about 9.0% and 54.8%, respectively. Median pack-years (SD) of smoking for ex- and current-smokers were 22.7 (19.9). Overall 222 participants (38.6%) and 139 participants (24.2%) had forced expiratory volume in 1 second ($FEV_1$) and forced vital capacity (FVC) measurements < 80% predicted, and 217 participants (37.7%) had $FEV_1/FVC$ results < 70%. A total of 249 individuals (43.8%) had DLCO values < 80% predicted and only 75 (13.2%) had DLCO/VA results < 80% predicted. A total of 147 participants (25.6%) had peak expiratory flow (PEF) measurements < 80% predicted. The presence of ARDs lowered the lung function measurements compared to those of healthy individuals exposed to asbestos. Conclusion: Lung function measurement differs in individuals with different ARDs. Monitoring of lung function among asbestos-exposed populations is a simple means of facilitating earlier interventions.

• Journal of the Optical Society of Korea
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• 제20권5호
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• pp.607-613
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• 2016

The pleura is known as an end target organ of exposure to toxic environmental materials such as fine particulate matter and asbestos. Moreover, long-term exposure to hazardous materials can eventually lead to fatal lung disease such as diffuse pleural fibrosis or mesothelioma. Chest computed tomography (CT) and ultrasound are gold standard imaging modalities for detection of advanced pleural disease. However, a diagnostic tool for early detection of pleural reaction has not been developed yet due to difficulties in imaging ultra-fine structure of the pleura. Optical coherence tomography (OCT), which provides cross-sectional images of micro tissue structures at a resolution of 2-10 μm, can image the mesothelium with a thickness of ~100 μm and therefore enables investigation of the early pleural reaction. In this study, we induced the early pleural reaction according to a time sequence after pleurodesis using talc, which has been widely used in the clinical field. The pleural reaction in talc grouped according to the time sequence (1st, 2nd, 4th weeks) showed a significant thickening (average thickness: 45 ± 7.5 μm, 80 ± 10.7 μm, 90 ± 12.5 μm), while the pleural reaction in sham and normal groups showed pleural change from normal to minimal thickening (average thickness: 16 ± 5.5 μm, 17 ± 4.5 μm, 15 ± 6.5 μm, and 12 ± 7.5 μm, 13 ± 2.5 μm, 12 ± 3.5 μm). The measurement of pleural reaction by pathologic examinations was well-matched with the measurement by OCT images. This is the first study for measuring the thickness of pleural reactions using a biophotonic modality such as OCT. Our results showed that OCT can be useful for evaluating the early pleural reaction.

• Tuberculosis and Respiratory Diseases
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• 제43권5호
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• pp.786-791
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• 1996

저자들은 흉통을 주소로 내원하여 흉막 조직검사상 leukocytoclastic vasculitis로 확진된 혈관염에 의한 양측성 흉막염이 발생한 공피증 1례를 경험하였기에 문헌 고찰과 함께 보고하는 바이다.

• Korean Journal of Radiology
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• 제1권2호
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• pp.73-78
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• 2000

Objective: To describe the HRCT findings of cytomegalovirus (CMV) pneumonia in non-AIDS immunocompromised patients Materials and Methods: This retrospective study involved the ten all non-AIDS immunocompromised patients with biopsy-proven CMV pneumonia and without other pulmonary infection encountered at our Medical Center between January 1997 and May 1999. HRCT scans were retrospectively analysed by two chest radiologists and decisions regarding the findings were reached by consensus. Results: The most frequent CT pattern was ground-glass opacity, seen in all patients, with bilateral patchy (n = 8) and diffuse (n = 2) distribution. Other findings included poorly-defined small nodules (n = 9) and consolidation (n = 7). There was no zonal predominance. The small nodules, bilateral in eight cases and unilateral in one, were all located in the centrilobular region. Consolidation (n = 7), with patchy distribution, was bilateral in five of seven patients (71%). Pleural effusion and bilateral areas of thickened interlobular septa were seen in six patients (60%). Conclusion: CMV pneumonia in non-AIDS immunocompromised patients appears on HRCT scans as bilateral mixed areas of ground-glass opacity, poorly-defined centrilobular small nodules, and consolidation. Interlobular septal thickening and pleural effusion are frequently associated.

• 대한수의학회지
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• 제62권2호
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• pp.17.1-17.5
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• 2022

A 12-year-old castrated male Persian cat presented with abdominal distension and anorexia. The radiography revealed ascites, pleural effusion, and a cranioventral mediastinal mass. Ultrasonography showed a well-defined mass lesion within a thickened ileal segment with a transmural loss of layering and multiple hyperechoic nodules arising from the peritoneum. Computed tomography showed peritoneal thickening with contrast enhancement, a bulky heterogeneous ileal mass, and mesenteric involvement with diffuse nodules. An alimentary lymphoma was confirmed by fine needle aspiration of the small intestinal mass. This report describes the imaging features of lymphoma with peritoneal lymphomatosis in a cat.

• Journal of Korean Neurosurgical Society
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• 제48권2호
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• pp.181-184
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• 2010

A case of idiopathic hypertrophic cranial pachymeningitis (IHCP) misdiagnosed as an acute subdural hematoma is reported. A 37-year-old male patient presented with headache following head trauma 2 weeks earlier. Computerized tomography showed a diffuse high-density lesion along the left tentorium and falx cerebri. Initial chest X-rays revealed a small mass in the right upper lobe with right lower pleural thickening, which suggested lung cancer, such as an adenoma or mediastinal metastasis. During conservative treatment under the diagnosis of a subdural hematoma, left cranial nerve palsies were developed (3rd and 6th), followed by scleritis and uveitis involving both eyes. Magnetic resonance imaging (MRI) revealed an unusual tentorium-falx enhancement on gadolinium-enhanced T1-weighted images. Non-specific chronic inflammation of the pachymeninges was noticed on histopathologic examination following an open biopsy. Systemic steroid treatment was initiated, resulting in dramatic improvement of symptoms. A follow-up brain MRI showed total resolution of the lesion 2 months after steroid treatment. IHCP should be included in the differential diagnosis of subtentorial-enhancing lesions.

• Journal of Chest Surgery
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• 제29권6호
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• pp.664-668
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• 1996

미만형 악성 중피세포종은 4∼18개월의 평균생존율을 지닌 치명적인 질환으로 여겨져 왔다. 그러나 종양을 최대한 절제한 후 다양한 접근을 통한 치료방법으로 생존기간을 연장할 수 있다 최근 저자들은 미만형 악성 중피세포종을 가진 49세 남자환자를 치험하였기 에 보고하는 바이다. 환자 는 수개월 동안 혈성객담 및 우측흥통을 호소하였고, 단순흉부사진 및 컴퓨터 단층촬영에서 우측 전흥 강이 진한 음영으로 가리워 져 있었으며 많은 양의 혈성삼출, 미만성 늑막비후와 폐허탈, 파괴 등의 소견 을 보였다. 저자들은 늑막케절제술을 시행하였고, cisplatin과 mitomycin으로 보조적인 항암화학요법을 하였다. 그후 환자는 수 개월간 외래 추적관찰을 받았으며 술후 4개월 현재까지 국소재발의 증거는 없었다.