• Title/Summary/Keyword: differential inclusion

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SUFFICIENT CONDITIONS AND RADII PROBLEMS FOR A STARLIKE CLASS INVOLVING A DIFFERENTIAL INEQUALITY

  • Swaminathan, Anbhu;Wani, Lateef Ahmad
    • Bulletin of the Korean Mathematical Society
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    • v.57 no.6
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    • pp.1409-1426
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    • 2020
  • Let 𝒜n be the class of analytic functions f(z) of the form f(z) = z + ∑k=n+1 αkzk, n ∈ ℕ defined on the open unit disk 𝔻, and let $${\Omega}_n:=\{f{\in}{\mathcal{A}}_n:\|zf^{\prime}(z)-f(z)\|<{\frac{1}{2}},\;z{\in}{\mathbb{D}}\}$$. In this paper, we make use of differential subordination technique to obtain sufficient conditions for the class Ωn. Writing Ω := Ω1, we obtain inclusion properties of Ω with respect to functions which map 𝔻 onto certain parabolic regions and as a consequence, establish a relation connecting the parabolic starlike class 𝒮P and the uniformly starlike UST. Various radius problems for the class Ω are considered and the sharpness of the radii estimates is obtained analytically besides graphical illustrations.

A FAMILY OF HOLOMORPHIC FUNCTIONS ASSOCIATED WITH MUTUALLY ADJOINT FUNCTIONS

  • K.R. KARTHIKEYAN;G. MURUGUSUNDARAMOORTHY;N.E. CHO
    • Journal of applied mathematics & informatics
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    • v.42 no.4
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    • pp.997-1006
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    • 2024
  • In this paper, making use of symmetric differential operator, we introduce a new class of ℓ-symmetric - mutually adjoint functions. To make this study more comprehensive and versatile, we have used a differential operator involving three-parameter extension of the well-known Mittag-Leffler functions. Mainly we investigated the inclusion relation and subordination conditions which are the main results of the paper. To establish connections or relations with earlier studies, we have presented applications of main results as corollaries.

Preparation and Bioavailability of Oriental Medicine Containing Baicalin (III) : Preparation of Inclusion Complex and Bioavailability of Coprecipitated Product of Scutellariae Radix and Coptidis Rhizoma (바이칼린 함유 생약의 제제화 및 생체이용률 (제3보) : 황금 및 황련 공침물의 포접화합물 제조 및 생체이용률에 관한 연구)

  • Yang, Jae-Heon;Shin, Sang-Chul;Yoo, Hee-Doo
    • Journal of Pharmaceutical Investigation
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    • v.27 no.1
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    • pp.29-38
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    • 1997
  • Precipitation was formed during the preparation of decoction from a mixture of Scutellariae Radix and Coptidis Rhizoma. Baicalin and berberine were identified in this coprecipitated product (CPP) and these components were the active ingredients of two herbal medicine. We extracted respectively crude baicalin and berberine in Scutellariae Radix and Coptidis Rhizoma and prepared coprecipitate of crude baicalin-berberine. To increase the stability and bioavailability of coprecipitate of crude baicalin-berberine(CBB), which is slightly soluble drug, its inclusion complex was prepared and studied in this experiment. Inclusion complex of CBB with ${\beta}-cyclodextrin(CBB-{\beta}-CD)$ was prepared by freeze drying method and its characteristics were ascertained by means of solubility test, differential thermal analysis(DTA) and scanning electron microscope(SEM). The type of $CBB-{\beta}-CD$ is classified as $A_L-type$ on phase solubility diagram, and the stoichiometric ratio of CBB(baicalin in CBB) : ${\beta}-CD$ complex is 1:1 and formation constant is 151 $M^-1$. The solubility, dissolution, in situ absorption and serum concentration of $CBB-{\beta}-CD$ were significantly increased when compared to CBB. Therefore enhanced bioavailability of CBB by inclusion complexation with ${\beta}-cyclodextrin$ might be useful for dosage form design of active ingredients of two herbal medicine.

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Influence of inclusion of geosynthetic layer on response of combined footings on stone column reinforced earth beds

  • Maheshwari, Priti;Khatri, Shubha
    • Geomechanics and Engineering
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    • v.4 no.4
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    • pp.263-279
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    • 2012
  • The present paper deals with the analysis of combined footings resting on geosynthetic reinforced granular fill overlying stone column improved poor soil. An attempt has been made to study the influence of inclusion of geosynthetic layer on the deflection of the footing. The footing has been idealized as a beam having finite flexural rigidity. Granular fill layer has been represented by Pasternak shear layer and stone columns and poor soil have been represented by nonlinear Winkler springs. Nonlinear behavior of granular fill layer, stone columns and the poor soil has been considered by means of hyperbolic stress strain relationships. Governing differential equations for the soil-foundation system have been derived and solution has been obtained employing finite difference scheme by means of iterative Gauss Elimination method. Results of a detailed parametric study have been presented, for a footing supporting typically five columns, in non-dimensional form in respect of deflection with and without geosynthetic inclusion. Geosynthetic layer has been found to significantly reduce the deflection of the footing which has been quantified by means of parametric study.

Structure and Dynamics of Perfluoroalkanes and Their ${\beta}$-Cyclodextrin Inclusion Compounds Investigated by Solid-state $^{19}F$ MAS NMR

  • Tatsuno, Hiroto;Ando, Shinji
    • Proceedings of the Polymer Society of Korea Conference
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    • 2006.10a
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    • pp.305-305
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    • 2006
  • The molecular structure and dynamics of inclusion compounds (ICs) consisting of n-perfluoroalkane (PFA) guests and ${\Box}-cyclodextrin$ (${\Box}-CD$) host were investigated using $^{19}F$ magic angle spinning (MAS) and $^{1}H{\to}^{19}F$ cross polarization (CP) / MAS NMR spectroscopy with the aid of thermal analyses, FT-IR spectroscopy, X-ray diffraction, and $^{1}H{\to}^{19}F$ CP/MAS technique revealed that $C_{9}F_{20}$ molecules included in ${\Box}-CD$ undergo vigorous molecular motion and partly come out of the ${\Box}-CD$ channel above $80^{\circ}C$. In case of $C_{20}F_{42}/{\Box}-CD$, an exothermic peak is observed by differential scanning calorimetry (DSC) at ca. $40^{\circ}C$ which suggests that ${\Box}-CD$ molecules become mobile and commence rearrangements that form more ordered structures at higher temperatures.

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A Numerical Approach to Effective Elastic Moduli of Solids with Microinclusions and Microvoids (미소 개재물과 기공을 갖는 고체의 유효탄성계수에 대한 수치적 접근)

  • Kang, Sung-Soo
    • Journal of Advanced Marine Engineering and Technology
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    • v.33 no.6
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    • pp.852-859
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    • 2009
  • For the analysis of solids containing a number of microinclusions or microvoids, in which the mechanical effect of each inclusion or void, a numerical approach is need to be developed to understand the mechanical behavior of damaged solids containing these defects. In this study, the simulation method using the natural element method is proposed for the analysis of effective elastic moduli. The mechanical effect of each inclusion or void is considered by controlling the material constants for Gaussian points. The relationship between area fraction of microinclusions or microvoids and effective elastic moduli is studied to verify the validity of the proposed method. The obtained results are in good agreement with the theoretical results such as differential method, self-consistent method, Mori-Tanaka method, as well as the numerical results by rigid body spring model.

Phamaceutical Studies on the Drug (III) -Enhancement of Dissolution and Stability of Sulfamethoxazole by ${\beta}-Cyclodextrin$ Complexation- (약물의 약제학적 연구(제 3보) -${\beta}-$시클로덱스트린과의 복합체 형성에 의한 설파메톡사졸의 용출 및 안정성 향상-)

  • Lee, Hyeon-Jong;Kim, Soo-Uck;Seo, Seong-Hoon
    • Journal of Pharmaceutical Investigation
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    • v.18 no.4
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    • pp.181-186
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    • 1988
  • Inclusion complex of sulfamethoxazole with ${\beta}-cyclodextrin$ was prepared by freeze-drying method in molar ratios of 1:1, 1:1.25, 1:1.5 and 1:1.75, and the complex formation was identified by ultraviolet and infrared spectroscopies, powder X-ray diffractometry and differential scanning calorimetry. Dissolution rate and solid state stability of the complex were investigated in comparison with those of sulfamethoxazole powder and the physical mixture of sulfamethoxazole with ${\beta}-cyclodextrin$. As a result, the dissolution rate and the stability of solid complexes in various relative humidity conditions increased more remarkably than those of sulfamethoxazole powder and physical mixture. But the difference according to molar ratio of the complex was not recognized.

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ON SOME DIFFERENTIAL SUBORDINATION INVOLVING THE BESSEL-STRUVE KERNEL FUNCTION

  • Al-Dhuain, Mohammed;Mondal, Saiful R.
    • Communications of the Korean Mathematical Society
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    • v.33 no.2
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    • pp.445-458
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    • 2018
  • In this article we study the inclusion properties of the Bessel-Struve kernel functions in the Janowski class. In particular, we find the conditions for which the Bessel-Struve kernel functions maps the unit disk to right half plane. Some open problems with this aspect are also given. The third order differential subordination involving the Bessel-Struve kernel is also considered. The results are derived by defining suitable classes of admissible functions. One of the recurrence relation of the Bessel-Struve kernel play an important role to derive the main results.

Preparation of Microparticulate Itraconazole/Hydroxypropyl-$\beta$-cyclodextrin Inclusion Complexes Using a Supercritical Anti-Solvent [SAS] Process (초임계 역용매 공정을 이용한 Itraconazole/Hydroxypropyl-$\beta$-cyclodextrin 포접복합체 미세입자 제조)

  • 이상윤;김정규;김우식;유종훈;임교빈
    • KSBB Journal
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    • v.19 no.4
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    • pp.321-326
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    • 2004
  • Microparticles of an inclusion complex between itraconazole and 2-hydroxypropyl-${\beta}$-cyclodextrin (HP-${\beta}$-CD) were prepared using an environmentally-benign supercritical anti-solvent (SAS) process. In order to evaluate the degree of complexation, the thermal behavior of solid micro particulate complexes was investigated using differential scanning calorimetry. The experimental results obatined for the solubility and dissolution rate of the microparticulate inclusion complexes in a buffer solution of pH 1.2 showed that the complexation of itraconazole with HP-${\beta}$-CD results in a significant increase in the solubility and dissolution rate of itraconazole. For the microparticulate itraconazole/Hp-${\beta}$-CD inclusion complexes prepared by the SAS process, about 80% of itraconazole was found to dissolve in the buffer solution. Our experimental results confirmed that the SAS process is a promising method for the preparation of microparticles of water-insoluble drug/cyclodextrin inclusion complexes.

Studies on Suppositories of $Phenytoin-{\beta}-Cyclodextrin$ Inclusion Complexes (페니토인-${\beta}$-시클로덱스트린 포접 복합체의 좌제에 관한 연구)

  • Cha, Jae-Ho;Han, Kun
    • Journal of Pharmaceutical Investigation
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    • v.18 no.1
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    • pp.15-21
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    • 1988
  • An inclusion complex of phenytoin (PT) with ${\beta}-cyclodextrin\;({\beta}-CyD)$ in molar ratio of 1 : 1 was prepared, and the interaction between host and guest molecules was confirmed by infrared spectrometry, differential scanning calorimetry and X-ray diffractometry. Suppositories were prepared by the fusion method. PT and $PT-{\beta}-CyD$ complex were added to PEG 1540 and Witepsol H-15 under the vigorous stirring at $40^{\circ}C$. Content uniformity was tested for different formulations of the PT suppositories. The release rates were dependent on the K.P. V dissolution apparatus and the dialyzing tubing method. Then, the release rates were increased in the following order: $PT-{\beta}-CyD$ complex in PEG 1540>PT in PEG 1540>$PT-{\beta}-CyD$ complex in Witepsol H-15>PT in Witepsol H-15. The area under the curve and maximum blood concentration after rectal administration were increased in the following order: $PT-{\beta}-CyD$ complex in PEG 1540>PT in PEG 1540>$PT-{\beta}-CyD$ complex in Witepsol H-15>PT in Witepsol-15.

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