• 한국식품과학회지
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• 제41권4호
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• pp.435-440
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• 2009

잎녹차 추출물 보다는 분말녹차 추출물의 경우가 그리고 저장된 sample보다는 fresh sample의 AChE 저해활성이 상대적으로 높았고 이는 생리활성 물질의 추출효율성과 생리활성 물질의 특성 변화 측면에서 기인되는 것으로 판단된다. 또한 본 연구팀에서 구성한 저장 조건에서, 4주간의 짧은 저장기간이 3개월 저장조건보다는 우수한 효소 저해활성도를 나타냈다. 수분활성도 측면에서는 수분활성도 0.81의 조건을 갖는 sample에서의 효과가 비교적 우수했고, 3개월 저장하는 동안의 저장온도 조건은 효소 저해 활성도에 큰 차이를 보이는 요소로 작용하지 못했다. 다만 상온이나 냉장조건 보다는 냉동상태의 저장조건이 다소 우수한 것으로 판단된다. 결국 생리활성물질을 보다 효율적으로 추출할 수 있는 녹차의 상태와 처리 또는 섭취 농도가 더욱 중요한 것으로 사료되고, 추출 효율을 증가시키기 위해서는 잎 보다는 분말의 상태가 더 우수한 것으로 판단된다. 따라서 녹차 추출물은 acetylcholine성 신경세포의 기능을 강화시켜줄 수 있는 AChE 저해제로서 활용가치가 높을 것이다.

• Asian-Australasian Journal of Animal Sciences
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• 제25권11호
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• pp.1568-1574
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• 2012

Three Holstein steers in the growing phase, each with a ruminal cannula, were used to test the hypothesis that the synchronization of the hourly rate of carbohydrate and nitrogen (N) released in the rumen would increase the amount of retained nitrogen for growth and thus improve the efficiency of microbial protein synthesis (EMPS). In Experiment 1, in situ degradability coefficients of carbohydrate and N in feeds including Korean rice wine residue (RWR) were determined. In Experiment 2, three total mixed ration (TMR) diets having different rates of carbohydrate and N release in the rumen were formulated using the in situ degradability of the feeds. All diets were made to contain similar contents of crude protein (CP) and neutral detergent fiber (NDF) but varied in their hourly pattern of nutrient release. The synchrony index of the three TMRs was 0.51 (LS), 0.77 (MS) and 0.95 (HS), respectively. The diets were fed at a restricted level (2% of the animal's body weight) in a $3{\times}3$ Latin-square design. Synchronizing the hourly supply of energy and N in the rumen did not significantly alter the digestibility of dry matter, organic matter, crude protein, NDF or acid detergent fiber (ADF) (p>0.05). The ruminal $NH_3$-N content of the LS group at three hours after feeding was significantly higher (p<0.05) than that of the other groups; however, the mean values of ruminal $NH_3$-N, pH and VFA concentration among the three groups were not significantly different (p>0.05). In addition, the purine derivative (PD) excretion in urine and microbial-N production (MN) among the three groups were not significantly different (p>0.05). In conclusion, synchronizing dietary energy and N supply to the rumen did not have a major effect on nutrient digestion or microbial protein synthesis (MPS) in Holstein steers.

• 사상체질의학회지
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• 제33권2호
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• pp.37-46
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• 2021

Background According to the Sasang constitutional medicine, eating habits according to the characteristics of Sasang Constitution (SC) types affect management of chronic diseases and health conditions. The aim of this study is to identify the association between eating habits, such as breakfast, eating frequency, and energy intake, according to SC, and quality of life. Method This study is a cross-sectional study of people aged 33 to 55 years, sampled by stratification based on population distribution. The SC types were classified into Taeeumin (TE), Soeumin (SE), and Soyangin (SY) using a structured questionnaire (KS-15). Items examined regarding eating habits were whether the subjects had breakfast; the frequency of eating such as breakfast, lunch, dinner, and after-dinner snacks; and energy intake surveyed using a food frequency questionnaire. As for quality of life, SF-12, which is widely used worldwide to assess health conditions, was utilized. A regression analysis was conducted on the relations between eating habits according to SC and quality of life. Results The SC distribution of the 3,895 subjects was 47% for TE, 22% for SE, and 31% for SY. The scores indicating quality of life differed for TE and SY depending on whether they ate breakfast and eating frequency groups, and those of SE varied depending on levels of energy intake. A regression analysis having adjusted all covariates demonstrated for TE a positive relation between the eating frequency of three times per day or more (compared to 1.5 to 3 meals per day) and quality of life (B=1.365, p<0.001). For SE, there was a negative association between low energy intake (compared to adequate energy intake) and quality of life (B=-1.642, p=0.004). Meanwhile, no relation was found between eating habits and quality of life for SY. Conclusion This study identified the association between eating habits according to SC types and quality of life. For TE, it was found to be important to eat evenly dispersed adequate amounts as opposed to overeating or binging at once. For SE, adequate energy intake affected good quality of life. This study suggests that eating habits based on SC improve quality of life, and health management customized for each constitution should be performed in the future through proper eating habits.

• 동아시아식생활학회지
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• 제23권6호
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• pp.681-689
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• 2013

본 연구에서는 대학생의 음주 여부에 따른 식습관을 조사하여 앞으로 어떻게 개선해 나갈 것인가에 대해 살펴보았다. 전체 355명(남자 188명, 여자 167명)의 대학생을 대상으로 음주 여부에 따른 식습관 조사를 실시한 결과, 음주를 하는 비율은 남자 94.1%, 여자 93.4%로 나타났고, 이중 19세 이하 음주 비율이 남녀 모두 94.4%로 나타났다. 학년은 1학년이 가장 많았는데, 이 중 음주를 하는 비율은 95.3%로 나타났다. 음주 여부에 있어서 식습관의 차이는 크게 보이지 않았다. 점심 식사를 함께 하는 사람은 음주, 비 음주 집단의 각각 55.9%, 59.1%가 가족보다는 친구와 함께 식사를 하였고, 음주 집단 내에서 식사 소요 시간은 남자는 10분 미만(20.9%), 여자는 20~30분 미만(35.3%)이라는 응답이 나타나, 여자의 식사시간이 10~20분 정도 높게 나타났다(p<0.001). 또한 결식률은 음주, 비 음주 집단 각각 49.5%, 54.5%가 아침 식사는 가끔 먹는다가 가장 많았고, 저녁 식사의 경우 꼭 먹는다의 비율이 각각 59.2%, 68.2%로 가장 높게 나타났다. 음주 집단 내에서 남자(29.9%)보다 여자(47.4%)가 저녁을 가끔 먹는다는 응답이 많아 여학생의 다이어트에 의한 저녁 결식률이 높음을 알 수 있었다(p<0.01). 아침 식사 형태는 음주, 비 음주 집단 각각 83.5%, 83.4%로 밥이 가장 많았고, 비 음주 집단 내에서 남자는 주로 학교식당(63.6%)에서, 여자는 주로 학교 밖 음식점(72.7%)에서 점심 식사를 한다는 응답이 더 높게 나타났다(p<0.05). 음주 집단 내에서 과식 횟수는 여자는 주 1~2회(61.5%), 남자는 과식을 거의 하지 않는다(27.7%)라고 나왔다(p<0.05). 주요 식품군 섭취율에 있어서 음주 및 비 음주, 남자와 여자의 차이가 크게 나타나진 않았다. 곡류 및 전분류는 매일(음주 61.3%, 비음주 61.4%), 육류 및 육류 가공품(음주 40.8%, 비음주 40.3%), 채소(음주 33.0%, 비음주 32.7%) 및 과일류(음주 27.9%, 비음주 29.1%)는 주 3~4회 섭취한다는 응답이 가장 많았다. 우유 및 유제품의 경우에는 음주 집단(주 1~2회 28.5%)보다 비 음주 집단이 주 3~4회(31.8%)로 섭취횟수가 높게 나타났으며, 음주 집단 내에서 여자(주 1~2회 26.3%)보다 남자(매일 섭취한다 31.1%)의 섭취횟수가 높게 나타났다(p<0.001). 유지 및 당류는 음주, 비 음주 각각 33.3%, 36.4%로 주 1~2회 섭취하는 것으로 나타났다. 이상의 결과로 볼 때, 대부분의 남녀 학생들이 음주를 하는 경향이 있으며, 음주 여부에 따른 식습관의 차이보다는 성별에 따른 식습관이 다르게 나타나는 것을 볼 수 있다. 이에 따라 대학생 시기의 올바른 식습관 확립 및 균형 잡힌 식품 섭취를 통해 건강한 생활을 영위할 수 있도록 학교나 지역 사회 및 정부 차원에서 지속적이고 체계적인 영양 교육이 필요하다. 또한 일단 성립된 바람직하지 않은 식습관은 쉽게 변화하지 않으므로 이론 위주의 영양 교육보다는 실제적인 행동변화를 유도할 수 있는 적극적인 영양 교육 프로그램이 필요하다. 바람직한 식생활 영위를 위해서 영양소 및 식품에 관한 지식을 전달하는 것뿐만 아니라, 영양적으로 균형 잡힌 식사를 하려는 적극적인 태도 및 실천 의욕을 고취시키고, 그 점을 개선하고자 하는 식행동으로 변화를 유도할 수 있는 영양 교육의 기회 부여가 절실히 필요하다고 사료된다.

• 대한영양사협회학술지
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• 제2권2호
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• pp.105-111
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• 1996

The trial was conducted to assess the impact of consulting through telephone on body weight reduction among 18 obese adult women. The degree of obesity, food intake pattern, and life style were examined through phone calls. Subjects visited our clinic and their body fat percentages were measured using impedance fat meter (model SIF-891), and were recommended and recorded to have a low calory diet with changes in the food habit and behavior. The study results are as follows: 1. There is a positive relationship between food habit, lifestyle, obese degree, and fat percentage. 2. 8-10kg and 5kg reductions in the body weight were observed among 14 subjects and 2 subjects, respectively. However, 2 subjects maintained their body weights. 3. The body reduction curve looked like a stairway (type) with low slope and was related with food intake amount. 4. It was possible to have the adequate protein intake only through the vegetable diet. 5. 15 out of 18 subjects were on the prescribed low calory diets for 3 days. Therefore, there is a time limitation to follow the diet treatment. 6. A body weight reduction altered dietary intake of foods which were rich in sweet taste, and the favorite foods were chocolate and candy.

• 대한임상검사과학회지
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• 제40권2호
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• pp.98-105
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• 2008

Colorectal carcinoma from various cancers is fourth ranked occurred to Korean. Due to western dietary life, this cancer has been increased continuously. Therefore, the further study will be needed to find a candidate gene involved in the development and progression of colorectal carcinoma as well as to diagnose and treatment helpfully. The purpose of this study was designed to find a carcinogenesis gene using microsatellite marker on chromosomes 7th and 20th from 30 colon cancer patients. The amplification was investigated in order of D20S97 57% (17/30), D20S101 57% (17/30), D20S119 53% (16/30), D7S483 50% (15/30), D7S495 47% (14/30), D7S498 47% (14/30). The genetic mutation pattern depends on loci of colorectal carcinoma was shown highly amplified with 3.77 from colon cancer than with 2.08 from right colorectal carcinoma (P<0.018). The genetic mutation with lymph nodes was investigated higher with 4.13 at metastasized group than with 1.93 at non-metastasized group (P<0.001). There was no difference at comparison between histological classfication and serological CEA increase as well as on genetic mutated pattern depends on disease stage. It is suggested that the amplification on chromosomes 7q and 20q determines a pivotal role from first stage to metastasis cancer and also functions as an useful marker on diagnosis and treatment of colorectal carcinoma patients as well as follow-up checkup. Recently, the diagnosis and study using genetic analyzer are necessary for efficient application. Fortunately, several university hospitals run this genetic analyzer currently so it is expected that this method makes full use of clinical application.

• Asian-Australasian Journal of Animal Sciences
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• 제10권5호
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• pp.528-533
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• 1997

Twenty four female Sprague-Dawley rats weighing about 190 g were used to examine changes in muscle cAMP concentrations and steady-state levels of skeletal muscle ${\alpha}$-actin mRNA during chronic administration of cimaterol, a ${\beta}$-adrenergic agonist. Cimaterol was mixed in a powdered rat diet at 10 mg/kg diet. At 3 and 21 days after the start of treatment, skeletal muscle and heart samples were collected for the measurement of cAMP concentrations and skeletal muscle ${\alpha}$-actin mRNA levels. Cimaterol increased (p < 0.01) body weight gain gradually during the first seven days of the trial period, but not thereafter. Most skeletal muscle weights and the ratio of muscle weight to body weight were increased (p < 0.05) by cimaterol treatment both at 3 and 21 days. Heart weight was also increased (p < 0.05) by cimaterol treatment at 3 and 21 days, but the ratio of heart weight to body weight was increased (p < 0.05) only at 3 day. Cimaterol decreased (p < 0.05) cAMP concentration of gastrocnemius muscle at both 3 and 21 days after treatment. However, cimaterol tended (p = 0.07) to increase cAMP concentration at 3 days in the heart. Cimaterol tended (p = 0.08) to increase the steady-state level of ${\alpha}$-actin mRNA by 60% in gastrocnemius muscle at 3 days but had no effect at 21 days. The results indicate that the pattern of hypertrophic response to chronic dietary administration of cimaterol is different between cardiac and skeletal muscle. In skeletal muscles it appears that the hypertrophy induced by cimaterol is partly due to stimulated myofibrillar protein synthesis at a pre-translational level.

• Asian Pacific Journal of Cancer Prevention
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• 제17권9호
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• pp.4301-4306
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• 2016

Background: Cancer is a burden on humanity and ranks as a leading cause of morbidity and mortality in China. Shanxi province has its unique cancer patterns and the burden is increasing. In this study, we aimed to assess the pattern of dietary habits and life-style in Shanxi, a high-risk area for upper gastrointestinal cancers in China and further evaluate the trends in cancer incidence and mortality based on registered data. Materials and Methods: Data on lifestyle, diet, physical activity were obtained from the household health survey at Zhongyang from 2013 to 2015. Cancer diagnoses were reported to Shanxi Center for Disease Control and Prevention (SCDCP). Population-based cancer incidence data and mortality data of 2012 were collected from the SCDCP. All incidence and death rates were expressed per 100,000 populations. Univariate analysis was performed using the Chi-squared test or Fisher's exact test. Results: Overall, deficiencies in fresh fruits and vegetable food, and intake of hot food, salted food, or pickled food are serious problems in Shanxi, especially in rural areas. Upper gastrointestinal cancers were the most commonly diagnosed cancers, and the incidence in rural areas is higher than those in urban areas. Cervical cancer is the most common cancer for females. Moreover, the agespecific incidence exhibited an increased trend before 40 years old. Consistent with the previous literature, our epidemiological investigation results suggest that lifestyle, nutrition deficient, and infections were major risk factors for upper gastrointestinal cancers or cervical cancer in Shanxi. Facing a serious situation, we further explored defensible recommendations for the general public in order to promote changes in environments that support healthful eating and physical activity habits, to reduce cancer risk. Conclusions: Our results present the current cancer trends in Shanxi and its related etiologic risk factors and provide a theoretical basis to guide public health efforts to prevent and control cancers in the province.

• 대한영양사협회학술지
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• 제26권2호
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• pp.85-100
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• 2020

Eating alone has recently become a very common dietary pattern in modern society. This study investigated the relationship between the frequency of eating alone and health related issues including chronic diseases, depression, and the quality of life (QOL). The 2016 Korea National Health and Nutrition Examination Survey provided the basic data for this study. According to the general analysis of 4,910 adults aged over 19 years or older, the average age in the 'eating alone' group was significantly higher (P<0.001), and the ratio of single-person households was significantly higher as the number of times of eating alone increased (P<0.001). Analysis of the relationship between the risk factors of metabolic syndrome according to the number of times eating alone, using logistic regression analysis, showed that the odds ratio of metabolic syndrome in the 'two times eating alone a day' group was approximately 1.3 times higher (OR=1.275) after being corrected for gender, age and energy intake. For the 'three times eating alone a day' group, the metabolic syndrome odds ratio was higher in all models except for model 1 and 5 (P for trend<0.05). The prevalence of depression using patient health questionnaire-9 (PHQ-9) was higher as the number of eating alone increased, and the QOL was inversly related with the number of meals eating alone (P for trend<0.01). We hope the results of this study will raise awareness of the health of those people who eat alone and lay the groundwork for individuals who eat alone and gain social attention.

• 한국환경농학회지
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• 제41권3호
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• pp.153-157
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• 2022

BACKGROUND: The residue dissipation pattern of pesticides for agricultural products during the pre-harvest period after the final application is important to prevent the maximum residue limit (MRL) violations in domestic and export markets. The MRL violations of carbendazim are observed more often in chamnamul by pesticide residue management surveys by the Ministry of Food and Drug Safety. The residue level at the pre-harvest interval (PHI) and the residue dissipation constant from the critical good agricultural practice (cGAP) trials could be estimated to meet the MRL and pose a health risk to consumers. METHODS AND RESULTS: Chamnamuls were harvested at 0, 1, 3, 5, 7, 10, and 14 days after application of carbendazim in accordance with critical GAP. The residue analysis in chamnanul was performed by HPLC-DAD with the C₁₈ column. The limit of quantitation of carbendazim was 0.04 mg/kg, and the recoveries were 74.4 - 95.8% at the two spiked levels (LOQ and 10LOQ) of carbendazim. The dissipation rates in chamnamul were calculated from the residues at the sampling days by statistical method at a 95% confidence level. The biological half-lives of residual carbendazim in the field trials 1 and 2 were 4.9 and 4.4 days, respectively. CONCLUSION(S): In this dissipation study, the residue concentrations at the recommended PHI were higher than the established MRL in Korea. Therefore, the MRL is proposed based on the residue data sets from the trials conducted at the same cGAP and the dietary exposure assessment.