• 제목/요약/키워드: diagnostic point

검색결과 472건 처리시간 0.029초

종이기반 미세유체 분석소자를 활용한 현장검사 기술과 그 응용 (Recent Advances in a Microfluidic Paper-based Analytical Devices and its Point of Care Testing Applications)

  • 유용경;김천중;이준우;이정훈
    • 세라미스트
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    • 제21권3호
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    • pp.293-301
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    • 2018
  • Paper-based analytical devices (${\mu}PAD$) are highly advantageous for portable diagnostic systems owing to their low costs and ease of use. ${\mu}PADs$ are considered as the best candidates for realizing the World Health Organization (WHO) ASSURED criteria: affordable, sensitive, specific, user-friendly, rapid and robust, equipment-free, and deliverable to end users. However, they have several limitations such as low sensitivity and accuracy. This article reports a mini review for a micro-fluidic paper-based analytical devices (${\mu}PAD$), especially for addressing low sensitivity and accuracy issues.

스마트폰 기반 Mobile SmartScope를 이용한 혈구 영상 분석 (Analysis of Blood Cell Images Using Smartphone-based Mobile SmartScope)

  • 박춘호;조명옥;이동희;김중경
    • 한국가시화정보학회지
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    • 제10권2호
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    • pp.25-31
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    • 2012
  • High-performance smartphones, equipped with a digital camera and an application software, can render conventional bench-top laboratory instruments mobile at affordable costs. As the smartphone-based devices are portable and wireless, they have wide applications especially in providing point-of-care (POC) tests in resource-constrained areas. We developed a hand-held diagnostic system, Mobile SmartScope, which consists of a small optical unit integrated with a smartphone. The performance of the SmartScope was favorably compared with that of conventional light microscopy in detecting and quantifying red blood cells. We also evaluated the fluorescence detection limit of the SmartScope incorporated with a blue light-emitting diode and appropriate optical filters by using fluorescently labeled microbeads for intensity calibration.

Graphical Methods for the Sensitivity Analysis in Discriminant Analysis

  • Jang, Dae-Heung;Anderson-Cook, Christine M.;Kim, Youngil
    • Communications for Statistical Applications and Methods
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    • 제22권5호
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    • pp.475-485
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    • 2015
  • Similar to regression, many measures to detect influential data points in discriminant analysis have been developed. Many follow similar principles as the diagnostic measures used in linear regression in the context of discriminant analysis. Here we focus on the impact on the predicted classification posterior probability when a data point is omitted. The new method is intuitive and easily interpretable compared to existing methods. We also propose a graphical display to show the individual movement of the posterior probability of other data points when a specific data point is omitted. This enables the summaries to capture the overall pattern of the change.

A Study on the Effects of Silver Spike Point on Functional Constipation Improvement

  • Park, Joo Hyun;Koo, Ja Pung;Um, Ki Mai
    • 국제물리치료학회지
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    • 제9권2호
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    • pp.1490-1493
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    • 2018
  • The purpose of this study was to investigate the effects of the Silver Spike Point (SSP) on functional constipation. The subjects were 14 female students who attended a university located in Gyeonggi province and consent to participate in this study. The inclusion criteria were the fulfillment of two or more diagnostic criteria of Rome III or scoring four or more points in Constipation Assessment Scale (CAS). The CAS score was significantly decreased in the experimental group (from $14.29{\pm}1.38$ to $6.86{\pm}2.91$) (p<.05), however, there was no significant change in the control group (from $14.29{\pm}1.49$ to $14.14{\pm}1.21$). The present study suggests that SSP intervention is effective in mitigating constipation.

MCNPX 프로그램을 통한 일반 X선 검사 시 검사실 내 공간선량분포 (Spatial Dose Distribution for Diagnostic X-ray Examination within X-ray Room using the MCNPX Program)

  • 이동연;이진수
    • 한국콘텐츠학회논문지
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    • 제15권11호
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    • pp.298-306
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    • 2015
  • 본 연구는 진단용 X선 검사 시 사용하고 있는 부가필터의 재질(Cu, Ni, CaWO4, Gd+Ba)을 다양화하여 그에 따른 검사실 내의 공간선량을 평가 한 후 적합한 재질을 찾아 제시하고자 하였다. 실험은 몬테칼로 기법을 바탕으로 하는 MCNPX 프로그램을 사용하여 흉부와 복부검사를 선택하여 모의실험을 진행하였다. 그 결과 각 재질별 선량은 모의피폭체가 위치한 곳을 중심으로 반경 50 cm 인 지점의 평균 산란선량은 모의피폭체 표면선량의 약 62%, 반경 100 cm인 지점은 평균 약 47% 정도 측정되었다. 결과에 따라 현재 상용화 되어 있는 Al 재질을 Cu, Ni 재질이 충분히 대체가능 할 것으로 판단된다. 다만 원자번호와 밀도의 차이로 인하여 그 두께를 Al의 약 1/10 정도로 조정을 해서 사용하면 적합할 것이다.

Antioxidant profile of whole saliva after scaling and root planing in periodontal disease

  • Kim, Sang-Chul;Kim, Ok-Su;Kim, Ok-Joon;Kim, Young-Joon;Chung, Hyun-Ju
    • Journal of Periodontal and Implant Science
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    • 제40권4호
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    • pp.164-171
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    • 2010
  • Purpose: This study compared the total antioxidant status (TAS) and superoxide dismutase (SOD) activity in the saliva of periodontally compromised patients before and after scaling and root planing (SRP) to assess their diagnostic utility. Methods: Severe chronic periodontitis patient (test group) and subjects with no attachment loss, sites showing a 3 mm or more probing depth and a sulcus bleeding index < 10% (control group) were enrolled in this study. Saliva sampling and clinical examination were performed at one week, one month and 3 months after SRP. The TAS and SOD activity in each patient's saliva was measured for the comparative analysis between the groups. Results: In the test group, the TAS decreased directly after SRP. With time, it increased slightly and was relatively unchanged compared to the baseline. In the control group, the TAS also decreased immediately after SRP but increased gradually with time until 3 months. The SOD activity in the test and control subjects decreased immediately after SRP until 1 month. At 3 months, the SOD activity had increased. Both groups had a similar profile of SOD activity. However, the SOD activity of the control group was significantly higher than that of the test group at each point in time (P < 0.05). Conclusions: There was a significant difference in the total salivary antioxidant level between the periodontitis and healthy or gingivitis (control) group during the experiment period. The total antioxidant level in the saliva was higher in the patients with severe chronic periodontitis than the healthy or gingivitis control before SRP. The SOD activity of the periodontitis patients was lower than the control at each time point. These findings conclusively reveal the possible use of saliva as a diagnostic tool for periodontal health.

정상교합자의 치열궁과 기저골 형태에 대한 3차원적 연구 (Three dimensional structural analysis between dental arch and basal bone in normal occlusion)

  • 김지태;이진우
    • 대한치과교정학회지
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    • 제41권4호
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    • pp.224-236
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    • 2011
  • 본 연구는 정상교합자의 치열궁과 기저골 형태를 파악하기 위해 시행하였다. 정상교합자 27명(남-15명: 25Y $10M{\pm}4Y$ 4M/여-12명: 26Y $1M{\pm}7Y$ 4M)을 대상으로 두개골의 전산화 단층촬영을 시행하고 입체영상을 제작한 뒤, 상악 중절치의 FA point의 중점을 원점으로 하는 3차원 좌표계를 형성하였다. 또한 상악 교합평면과 평행한 면으로 절단하여 상하악의 치열궁과 기저골의 형태에 대해 분석하였다. 상하악기저골은 A point, B point 부위와 양측 제1대구치 부위의 좌표에서 통계적으로 유의한 차이가 나타나지 않았다. 또한 상하악의 치열궁은 기저골악궁에 비해 전치부에서 순측으로 위치하였다. 또한 치열궁과 기저골악궁의 협설측 교차는 상악은 대구치 부위에서, 하악은 소구치 부위에서 이루어졌다.

"침구갑을경(鍼灸甲乙經)"의 용어체계(用語體系)에 관한 연구 (A Study on Terminology in ZhenJiuJiaYiJing(鍼灸甲乙經))

  • 박찬영;이병욱;김기욱
    • 대한한의학원전학회지
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    • 제26권3호
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    • pp.127-139
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    • 2013
  • Objectives : In the traditional oriental medicine, efforts to utilize the knowledge system so called Ontology have been achieved for systemic researches and efficient propagation of knowledge on oriental medicine. So far, in Korea, studies on drug ontology, pathological ontology, Cold Damage ontology and diagnostic ontology had been implemented, however, any development of ontology in the field of Acupuncture &, Moxibustion has not been achieved. Methods : We used Microsoft Access to collect terms in ZhenJiuJiaYiJing. The terms are related to human body area and structure. And then we built relationship of 'part of' and 'criterion of acupuncture point location' between the terms. Result & Conclusions : The terms used to explain acupuncture points in order to describe the position of acupuncture point name in ZhenJiuJiaYiJing were 8 words concerning different name of acupuncture point(穴名) 109, body part name(人體部位名稱) 150, meridian(經脈) 6 and structure(構造物).

Blink reflex changes and sensory perception in infraorbital nerve-innervated areas following zygomaticomaxillary complex fractures

  • Park, Young Sook;Choi, Jaehoon;Park, Sang Woo
    • Archives of Plastic Surgery
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    • 제47권6호
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    • pp.559-566
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    • 2020
  • Background Infraorbital nerve dysfunction is commonly reported after zygomaticomaxillary complex fractures. We evaluated sensory changes in four designated areas (eyelid, nose, zygoma, and lip) innervated by the infraorbital nerve. This evaluation was conducted using the static two-point discrimination test and the vibration threshold test. We assessed the diagnostic significance of the blink reflex in patients with infraorbital nerve dysfunction. Methods This study included 18 patients, all of whom complained of some degree of infraorbital nerve dysfunction preoperatively. A visual analog scale, the infraorbital blink reflex, static two-point discrimination, and the vibration threshold were assessed preoperatively, at 1 month postoperatively (T1), and at a final follow-up that took place at least 4 months postoperatively (T4). The results were analyzed using a multilevel generalized linear mixed model. Results Scores on the visual analog scale significantly improved at T1 and T4. The infraorbital blink reflex significantly improved at T4. Visual analog scale scores improved more rapidly than the infraorbital blink reflex. Two-point discrimination significantly improved in all areas at T4, and the vibration perception threshold significantly improved in the eyelid at T4. Conclusions Recovery of the infraorbital blink reflex reflected the recovery of infraorbital nerve dysfunction. We also determined that the lip tended to recover later than the other areas innervated by the infraorbital nerve.

서울시 홍대상권 내 업종변화 필지의 공간적 특성 분석 - 상업 젠트리피케이션의 관점에서 - (Analysis of Spatial Characteristics of Business-Type-Changed Parcel in Hongik-University Commercial Area, Seoul - Focused on the View Point of Commercial Gentrification -)

  • 김동준;김기중;이승일
    • 국토계획
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    • 제54권2호
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    • pp.5-16
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    • 2019
  • The purpose of this study is to analyze the spatial characteristics of business-type-changed parcel in the Hongik-University commercial area, from the view point of commercial gentrification. A commercial gentrification occurs through a business-type-change in a spatial basic unit (microscopic spatial unit such as parcel) of an area which has not been considered in relavent policies and research. So, this study analyzed the spatial characteristics of business-type-changed parcels using the Cox's proportional hazard regression model. The main results of this study are as follows. First, as new developments in the adjacent area occur, the business-type-change probability increases. Second, by the commercial area division, the business-type-change probability is different. Finally, the accessibility is better, the probability is higher. These results could suggest that a consideration of the spatial characteristics form microscopic viewpoint is necessary to understand the commercial gentrification. And these could be used as basic data for a gentrification diagnostic and management system, which can predict gentrification from the view point of business-type-change on the basis of a parcel.