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The reactive oxygen species-total antioxidant capacity score is a new measure of oxidative stress to predict male infertility

  • Sharma, Rakesh K.;Pasqualotto, Fabio F.;Nelson, David R.;Thomas Jr, Anthony J.;Agarwal, Ashok
    • 대한생식의학회:학술대회논문집
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    • 2000.06a
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    • pp.29-35
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    • 2000
  • The imbalance between reactive oxygen species (ROS) production and total antioxidant capacity (TAC) in seminal fluid indicates oxidative stress and is correlated with male infertility. A composite ROS-TAC score may be more strongly correlated with infertility than ROS or TAC alone. We measured ROS, TAC, and ROS-TAC scores in semen from 127 patients and 24 healthy controls. Of the patients, 56 had varicocele, eight had varicocele with prostatitis, 35 had vasectomy reversals, and 28 had Idiopathic infertility. ROS levels were higher among infertile men, especially those with varicocele with prostatitis (mean ${\pm}$ SE, 3.25 ${\pm}$ 0.89) and vasectomy reversals (2.65 ${\pm}$ 1.01). All infertility groups had significantly lower ROS-TAC scores than control. ROS-TAC score identified 80% of patients and was significantly better than ROS at identifying varicocele and idiopathic infertility. The 13 patients whose partners later achieved pregnancies had a mean ROS-TAC score of 47.7 ${\pm}$ 13.2, similar to controls but significantly higher than the 39 patients who remained infertile (35.8 ${\pm}$ 15.0; P < 0.01). ROS-TAC score is a novel measure of oxidative stress and Is superior to ROS or TAC alone in discriminating between fertile and infertile men. Infertile men with male factor or idiopathic diagnoses had significantly lower ROS-TAC scores than controls, and men with male factor diagnoses that eventually were able to initiate a successful pregnancy had significantly higher ROS-TAC scores than those who failed.

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Formation of ghost images due to metal objects on the surface of the patient's face: A pictorial essay

  • Ramos, Barbara Couto;da Silva Izar, Bruna Raquel;Pereira, Jessica Lourdes Costa;Souza, Priscilla Sena;Valerio, Claudia Scigliano;Tuji, Fabricio Mesquita;Manzi, Flavio Ricardo
    • Imaging Science in Dentistry
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    • v.46 no.1
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    • pp.63-68
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    • 2016
  • Panoramic radiographs are a relatively simple technique that is commonly used in all dental specialties. In panoramic radiographs, in addition to the formation of real images of metal objects, ghost images may also form, and these ghost images can hinder an accurate diagnosis and interfere with the accuracy of radiology reports. Dentists must understand the formation of these images in order to avoid making incorrect radiographic diagnoses. Therefore, the present study sought to present a study of the formation of panoramic radiograph ghost images caused by metal objects in the head and neck region of a dry skull, as well as to report a clinical case in order to warn dentists about ghost images and to raise awareness thereof. An understanding of the principles of the formation of ghost images in panoramic radiographs helps prevent incorrect diagnoses.

Psychiatric Consultation at a Newly Opened University Hospital (신설대학병원에서 1년간의 정신과 자문)

  • DokGo, Hyang;Bae, Jae-Nam;Kang, Min-Hee
    • Korean Journal of Psychosomatic Medicine
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    • v.6 no.1
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    • pp.46-58
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    • 1998
  • Objectives : This study was performed to evaluate the status of psychiatric consultation at a newly opened university hospital, to explore problems related to psychiatric consultation and to contribute for future consultation to be more systematic and more efficient. Methods: The subjects of this study were 284 patients hospitalized at Inha University Hospital between September 1, 1996 and August 31, 1997, who were referred for psychiatric consultation during hospitalization. This study was evaluated demographical characteristics of referred patients, resons for referral, recommendations by psychiatric consultant, clinical diagnoses, psychiatric diagnoses, relationship between referral time and hospitalization following the day of consultation and consultation referral types based upon psychiatrists' reports and patients' medical charts. Results : Most common patients referred to consultation were females aged 20s who visited at the department of internal medicine and related to the risk of suicidal attempts. Mood disorder was the most frequent psychiatric diagnosis, and the most common recommendations were to use psychopharmacological treatment along with outpatient visits. The 30% of subjects were referred to consultation within a day after hospitalization. In the case of consultation referral timing within two days and after three days, there was significant difference between early consultation and shorter hospitalization following the day of consultation. Most frequent type of consultation(29.6%) was categorized as IIIa type(physical complication type as a "Mending" request type). Conclusion : In review of consultation referral timing and consultation referral type of the subjects, who were referred for psychiatric consultation for one year at a newly opened University Hospital, referrals were found to be made within two days after their admission to hospital(50.7%), which was observed to be early request. We found that there was significant association between early consultation and shorter hospitalization following the day of consultation. The physical complication type(29.6%) which belongs to "Mending" request type was found to be the most frequent consultation referral type. This result indicates that more systematic psychiatric consultation is needed for the future.

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The Diagnostic Accuracy of Fine Needle Aspiration Cytology and the Diagnostic Usefulness of Galectin-3 Immunostaining for the Follicular Variant of Papillary Thyroid Carcinoma (소포성 갑상샘 유두암종의 세침흡인 세포검사의 정확도와 Galectin-3 면역염색의 유용성)

  • Jung, Chan-Kwon;Shin, Jung-Ha;Lee, Hyun-Seung;Lee, Ah-Won;Jung, Eun-Sun;Choi, Yeong-Jin;Lee, Kyo-Young
    • The Korean Journal of Cytopathology
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    • v.19 no.2
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    • pp.160-163
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    • 2008
  • The cytologic diagnosis of the follicular variant of papillary thyroid carcinoma (FVPTC) has become one of the common causes of false negative diagnoses when performing fine needle aspiration cytology (FNAC) of the thyroid gland. We retrospectively reviewed all the aspirates for which a diagnosis of FVPTC had been made based on the surgically excised specimens, regardless of the cytologic diagnosis. 145 FNACs was performed in 135 patients. The cytologic diagnoses were categorized as 2 unsatisfactory specimens (1.4%), 16 benign (11.0%), 49 atypical (33.8%) and 78 malignant lesions (53.8%). The tumor cells consistently showed significant nuclear overlapping, irregular nuclei and fine chromatin in all cases; however, nuclear grooves and inclusions were scarce. Galectin-3 immunostaining was performed on the cell blocks of 65 cases and this was positive for 45 cases (69.2%). The results of our study demonstrate that the determination of minimal cytologic criteria is needed to raise the sensitivity of detecting FVPTC by FNAC, and galectin-3 immunostaining is useful to make decisions on the surgical treatment of cytologically atypical thyroid nodules.

Study on Clinical Operating Measures of Authentic Therapy and Supplementary Therapy in Oriental Medicine (한의학 정통요법과 보조요법의 임상적 운용방안)

  • Lee Jae-Soo;Kwon Young-Kyu;Yang Chae-Ha;Kim Kwang-Joong
    • Journal of Physiology & Pathology in Korean Medicine
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    • v.20 no.1
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    • pp.215-223
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    • 2006
  • This research surveyed oriental medicine therapies currently used in oriental medicine circles by referring to oriental medicine books-based existing traditional authentic therapies, as well as market-sold supplementary therapy-related ordinary health books and Internet information, and supplementary therapy-related dissertations, reviewed the fundamental operating significance of these therapies, and pursued their clinical operating measures based on their clinical information as follows Various therapies currently used in oriental medicine circles are categorized into authentic therapies and supplementary therapies in oriental medicine. Authentic therapies in Oriental medicine are based on bodily self-vitality abilities, pursue positive methods of treating diseases, and include medication therapies, acupuncture therapies, and external therapies. Supplementary therapies in oriental medicine are based on bodily self-vitality abilities, pursue indirect methods of treating diseases, and consist of lifestyle therapy and body management therapy. Authentic and supplementary therapies in Oriental medicine are used either separately or together according to clinical treatment methods. In treating diseases, clinical operating methods exclusively based on traditional authentic therapies and supplementary therapies include Donguibogam (anthology of ancient oriental medicine), Uihakipmun (introduction to medicine), Somun school, and bodily acupuncture according to diagnoses of symptoms, as well as sasangbang (prescription based on four types of bodily constitution), myeongribang prescription, hyeongsangbang prescription, and bodily constitution-based acupuncture according to diagnoses of bodily constitutions. In clinical operation of Oriental medicine, supplementary therapies are parity duplicated dy alternative medicine. However, given patients' needs and clinical practicality, Oriental medicine circles should establish a system based on the fundamental viewpoint of Oriental medicine theories, and corresponding policies should also be researched.

Physical Activity and Hip Fracture in Elderly People : A Cohort Study in Korea (노인 인구에서 육체적 활동과 고관절 골절 발생간의 관련성 : 코호트 연구)

  • Youn, Kyung-Eun;Lee, Seung-Mi;Kim, Yoon-I;Park, Byung-Joo
    • Journal of Preventive Medicine and Public Health
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    • v.35 no.4
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    • pp.351-358
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    • 2002
  • Objective : To evaluate the relationship between physical activity and the risk of hip fracture in the elderly Korean people. Methods : The study population was a Physical Activity Subcohort (n=8,908) extracted from the Korean Elderly Pharmacoepidemiological Cohort (KEPEC). Physical activity information was obtained from a mailed questionnaire surveys. The outcome data was collected from claims data gathered between Jan. 1993 and Dec. 1998. A hospital survey relating to potential cases was conducted to confirm the final diagnoses. The abstracted data was reviewed by a medical doctor before the final diagnoses were confirmed. A mailing questionnaire survey was performed to obtain information on potentially confounding variables, including alcohol intake, smoking habits, weight, height and postmenopausal duration. There were 79 confirmed cases hospitalized due to hip fractures between Jan. 1993 and Dec. 1998. Relative risk of physical activity scores on the hip fracture, and their 95% confidence intervals, were estimated by a Cox's proportional hazard model using SAS for Windows ver.6.12. Results : Compared to the reference group, the adjusted relative risk of hip fracture associated with the most physical active category: after controlling for age, weight and alcohol intake in the males, and for weight, alcohol intake and postmenopausal duration in the females, were 1.04 (95% CI=0.35-3.06) and 0.f4 (95% CI=0.26-0.77), respectively. Conclusions : Physical activity may protect elderly women from hip fracture.

Clinical courses and diagnoses of neonates who are transferred due to mild respiratory distress soon after birth in a university hospital (일개 대학병원에서 출생 초기 경미한 호흡곤란을 주소로 전원된 신생아의 임상경과 및 진단)

  • Seo, Jee Hyue;Lee, Kyo Ho;Lee, Eun Sil
    • Journal of Yeungnam Medical Science
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    • v.31 no.2
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    • pp.89-93
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    • 2014
  • Background: This study was conducted to investigate the epidemiological features, clinical courses, and diagnoses of neonates who are transferred to neonatal intensive care unit of Yeungnam University Hospital due to tachypnea soon after birth. Methods: Based on medical records, we performed a retrospective study of neonatal intensive care unit admissions due to tachypnea from January 2010 to December 2013. Results: A total of 311 neonates were included in this study. The patient characteristics showed male predominance at 2.65:1. Among the 311 neonates with tachypnea, 127 (40.8%) neonates needed oxygen supply, and 54 (17.4%) neonates needed assisted mechanical ventilation. Transient tachypnea of the newborns (TTN) (158, 50.8%) showed the highest incidence, followed by pneumonia (63, 20.3%), extrapulmonary infection (37, 11.9%), respiratory distress syndrome (21, 6.8%), air leak (16, 5.1%), meconium aspiration syndrome (12, 3.9%), congenital heart disease (5, 1.6%), metabolic acidosis (3, 1%), primary pulmonary hypertension of newborns (2, 0.6%) and anemia (2, 0.6%). Conclusion: Although the neonates with tachypnea showed no other respiratory distress symptom, clinicians should be aware of the possibility of other pulmonary diseases as well as TTN and their extra-pulmonary causes. If tachypnea does not improve within a few hours, the clinician should consider further evaluation and management as soon as possible.

Ethernet Port를 이용한 차량 진단 모니터링 시스템의 설계

  • Shin, Ju-Young;Jang, Jong-wook
    • Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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    • 2009.10a
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    • pp.98-101
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    • 2009
  • Recently, there is use of the vehicle network for vehicle diagnostic method and Increased use of the vehicle protocol such as (CAN(Controller Area Network), MOST, LIN, FlexRay), Distributed control and data about the vehicle are being sought methods for real-time observation and monitoring and trend tends to have gone into this. In this case of automotive diagnostic module in today, there is Primarily to use DLC(Data Link Connector)Connector called self-check terminal. Generally, vehicle Diagnoses to use DLC Connector such as OBD2(On Board Diagnostics) Through Diagnostic Module(scanner). But there limit diagnostic as engine and powertrain part, and not consider user's perspective In this paper, By designing Vehicle diagnostic monitoring system using Ethernet Port, transmit and Receives CAN protocol vehicle data, and implement Easily monitoring system that provide and Diagnoses to provide vehicle's state and information to use PC.

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Feline Demographics and Disease Distribution in the Republic of Korea

  • Lee, Jongseok;Pak, Son-il;Lee, Kija;Choi, Hojung;Lee, Youngwon;Park, Inchul;Choi, Sooyoung
    • Journal of Veterinary Clinics
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    • v.39 no.5
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    • pp.217-225
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    • 2022
  • The population of pet cats has increased significantly, from 0.3% in 2002 to 5.6% in 2017. Large-scale feline demographic and disease data from Korea are lacking. The aim of this study was to investigate the demographic data (breed, sex, and age) and disease distribution of cats who visited private veterinary practices in Korea. Data including breed, sex, age, and disease, were compiled from 32,728 electronic medical records from 30 selected private veterinary practices, between January 1, 2016, and December 31, 2017. Diseases were classified based on the International Classification of Diseases 11 by the World Health Organization, and then compared and cross-analyzed according to breed, sex, and age. Korean shorthair was the most common breed. There was a high distribution of young cats, with 77.6% of the cats under 4 years of age, and an average age of 2.5 years. Diagnoses related to preventative medicine were the most frequent and diagnoses common to young cats had higher incidence. This demographic data and information about disease distribution can be used as a basis for future research and may be helpful for determining priorities in the diagnosis of diseases and establishing strategies for health management in cats.

Characteristics and changes in delivery and puerperium complicaion : Based on the 2006-2017 Korea National Hospital Discharge In-depth Injury Survey (출산 및 산후 합병증 행태의 특성과 변화 분석 : 퇴원손상심층조사자료를 이용하여)

  • Kyunghee, Lee;Jieun, Hwang
    • The Journal of Korean Society for School & Community Health Education
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    • v.23 no.4
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    • pp.29-39
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    • 2022
  • Objectives: The purpose of this study was to assess the incidence of delivery and puerperium complications in South Korea and analyze the correlations between the patient's characteristics and delivery and complications before and after 10 years. Methods: This study used the data from an Korean National Hospital Discharge In-depth Injury Survey. Cases of which the principal diagnosis and second diagnoses were disease classification ICD code O00-O99(Pregnancy, childbirth and the puerperium) were defined as the study subjects, and the first study group was divided as the year of discharge from 2005 to 2007, and the second study group from 2015 to 2017. Results: The number of patients discharged whose principal diagnosis or second diagnoses was O00-O99 was 21,598(Weighted 423,306) from 2005 to 2007 and 19,028(Weighted 364,384) from 2015 to 2017, which decreased by 13.9% compared to 10 years ago. The average age of discharged patients increased by about 2 years and was statistically significant (p<.0001). Factors associating spontaneous delivery, caesarean section and puerperium complication were hospitalization route, bed size, maternal age, length of hospital stay, and the year of discharge. Conclusion: Based on the results of this study, health and education policies and economic support for medical care for high-risk pregnancy and delivery management would be necessary continuously. In addition, policies to strengthen the medical system for high-risk pregnancy management in non-metropolitan areas with high fertility rates would also be needed.