• The Korean Journal of Health Service Management
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• v.9 no.2
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• pp.57-68
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• 2015

This study investigated factors that affect stress recognition, depression, suicidal thoughts and health-related quality of life for diabetics over 50 years of age. Five hundred one diabetics were surveyed who participated in the 4th Korea National Health and Nutrition Examination Survey 2009. The data were analyzed with multiple regression analysis and Structural Equation Model to determine the factors. The results are as follows. Men, older and lower income groups, those not involved in economic activities, smokers, and drinkers showed a lower quality of life (p<0.001). There was no correlation with moderate-intensity exercise. Stress recognition (t=-4.229, p<0.001), depression (t=-2.156, p<0.05), and suicidal thoughts (t=-3.274, p<0.001) had significant effects on the quality of life (p <0.001, $R^2=0.25$). The most important of these factors is stress. Being diagnosed as a diabetic changes the lives of patients, who come under stress from controlling their blood sugar level. Societal support should be developed to help patients cope with the challenges of diabetes.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.8 no.6
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• pp.1513-1518
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• 2007

This paper describes a design and implementation of diabetes management system based on PDA in the wireless Internet. Our system is a 3-Tier Client/Server model with client, server, middleware, and DB. The client has each PDA for patients and for doctors related to diabetics. The one is used for patients to manage this disease by themselves with, and the other is used for the doctors to monitoring the patients' data with. The server receive the daily data measured by the patients through wireless network, middleware mediate between an client(PDA) and server. As the result of implementation of the system, we expected that it manages to diabetic patients continually and systematically.

• International Journal of Industrial Entomology and Biomaterials
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• v.48 no.3
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• pp.156-162
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• 2024

This study aimed to evaluate and compare the inhibitory effects of extracts from Bombyx batryticatus (BBE) and Bombyx mori (BME) on α-glucosidase, DPP-4, and LDL oxidation activities, focusing on their potential applications in managing postprandial hyperglycemia and metabolic syndrome. The results demonstrated that both BBE and BME effectively inhibited α-glucosidase and LDL oxidation, with BBE exhibiting higher inhibitory activity than BME. HPLC analysis identified linolenic acid, linoleic acid, linolenic acid ethyl ester, pheophorbide a, and pyropheophorbide a as key compounds contributing to these effects. Notably, the identified unsaturated fatty acids and pheophorbides showed strong α-glucosidase inhibitory activity, surpassing that of acarbose, a standard diabetic drug. These results suggest that, in addition to the previously reported 1-DNJ and fibroin proteins, unsaturated fatty acids and chlorophyll-derived pheophorbides may play significant roles in glycemic control. Compounds, particularly those from BBE, present promising opportunities for the development of natural therapeutic agents for diabetes management. The study concludes that BBE and BME have strong potential as functional ingredients in future diabetes treatment strategies, possibly offering enhanced efficacy over conventional inhibitors.

• Korean Journal of Psychosomatic Medicine
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• v.12 no.2
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• pp.157-164
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• 2004

Objectives : This study was designed to investigate depression, anxiety, alexithymia, stress responses between well-controlled and poorly-controlled diabetic patients by glycated hemoglobin levels. Methods : The subjects were 55 diabetic patients(mean age : $49.9{\pm}9.9$, 27 men and 28 women) who were confirmed to have diabetes depending on the laboratory findings as well as clinical symptoms at the St. Vincent Hospital Diabetes Clinic, from Mar. 2004 to Aug. 2004. Korean version of Beck Depression Inventory(BDI), State and Trait Anxiety Inventory(STAI), Toronto Alexithymia Scale(TAS) and Stress Response Inventory(SRI) were used for assessment. Based on glycated hemoglobin levels, the patients were divided into 10 well-controlled group(below 7%) and 45 poorly-controlled group(above 7%). We compared BDI, STAI, TAS and SRI scores between two groups by independent t-test. Results 1) Well-controlled diabetics, compared with poorly controlled group, manifested decreased illness duration($12.2{\pm}55.4$months vs. $55.4{\pm}66.6 months)(p=0.000), but other demographic data showed no difference between two groups. 2) The STAI scores of poorly-controlled group were significantly higher in both state anxiety sores $(38.7{\pm}3.8 \;vs.\;43.7{\pm}6.7)(p=0.29)$ and trait anxiety scores$(36.9{\pm}5.7\;vs.\;41.5{\pm}6.4)(p=0.43)$ than well-controlled groups. 3) No significant differences were found in the score of BDI, TAS, SRI between well and poorly-controlled diabetic groups. Conclusion : The above results suggest that poorly-controlled diabetic patients are more likely to have higher anxiety level than well-controlled diabetic patients. However, there were no differences in depression, alexithymia, stress responses between two group. We suggest that physicians should consider integrated approaches for psychiatric problems in the management of diabetic patients.

• Proceedings of the KAIS Fall Conference
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• 2010.11b
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• pp.759-762
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• 2010

본 연구는 당뇨인지환자들의 당뇨 조절에 관계되는 요인들을 포괄적으로 반영하는 집단으로 분류한 후 이를 기반으로 보다 효율적인 당뇨관리사업을 할 수 있는 기초자료를 제공하기 위해 수행되었다. 연구를 위해 2007년, 2008년도 국민건강영양조사를 통해 검진에 참여한 당뇨인지환자 666명의 자료를 수집하여 분석하였다. 당뇨인지환자의 관리행태에 대한 군집분류는 K-means 기법을 이용하였다. 당뇨인지환자의 군집은 건강행태사업 대상군, 중점관리사업 대상군, 합병증검사사업 대상군으로 분류되었다. 당뇨 조절율을 높이기 위해서는 각 군집의 특성에 따라 보다 특화된 당뇨관리 프로그램이 적용되어야 할 것이다.

• Journal of Industrial Technology
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• v.42 no.1
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• pp.13-18
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• 2022

Diabetes mellitus is an abnormally high glucose level in the bloodstream. Several pharmaceuticals are administered to diabetic patients to control their glucose levels. Early diagnosis and proper glycemic management are essential in this situation to prevent further progression and complications. Biosensor-based detection has progressed and shown potential in portable and inexpensive daily assessment of glucose levels because of its simplicity, low cost, and convenient operation without sophisticated instrumentation. This review discusses various systemic aspects of non-invasive glucose monitoring, including materials for monitoring and managing diabetes.

• The Korean Journal of Food And Nutrition
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• v.21 no.4
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• pp.530-535
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• 2008

Evidence for the effects of different health behaviors, including diet, in elderly diabetes is currently limited. The aim of this study was to compare the quality of diet and health behaviors in Korean elderly T2DM patients, using a glycemic control. T2DM elders(>65 yr, n=48) were recruited and categorized by the concentration of glycated-hemoglobin HbA1c; subjects with HbA1c<7% were the good control(GC) group, and subjects with $HbA1c{\geq}8%$ constituted the poor control(PC) group. General characteristics, self-management behavior questionnaires, and 3-d diet records were all collected and assessed. No significant differences in general characteristics between GC and PC were detected, with the exception of a higher level of education in GC(p<0.05). A twofold longer duration of diabetes was observed in PC as compared to GC(p<0.01). The GC group did exercise for a longer time(p<0.001), and had an earlier beginning of diabetes self-management education (DSME) by healthcare practitioners using a team teach as compared with the PC group(p<0.05). The total dietary quality index(p<0.001) and individual index for carbohydrate(p<0.001) or vegetables and fruit(p<0.05) were better in GC than in PC. Therefore, the earlier DSME including intensive exercise and balanced diet selection should be expected to improve glycemic control in diabetic Korean elders.

• Health Policy and Management
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• v.22 no.2
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• pp.263-274
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• 2012

This study describes the hypertensive patients characteristics associated with the health incentive point program, and develops and analyzes a simple predictive model of participation in the program. Based on the Incheon Chronic Disease Management System(iCDMS), a model program of community partnership for hypertensive or diabetic patients detection and follow-up since 2005 in Incheon metropolitan city, a cross-sectional design was used in this study. An effective 10.844 adults sample was divided into groups according to participation in the health incentive point program and continuing treatment, and individual and health characteristics among groups were compared. Furthermore, the predictors associated with participation in the program were identified by the logistic regression analysis. After the health incentive point program in iCDMS was introduced, the number of hypertensive patients participation in the program increased 23.9 times which is vastly high given the various programs were provided. There were statistically significant differences among the groups: age(p=0.000), treatment compliance(p=0.000), and blood pressure control at the last measurement(p=0.000), in particular, between participation group(GroupI, n=246) and non-participation group(GroupIII, n=10,408). Furthermore, age over 60 years(OR: 0.33), treatment compliance(OR: 3.49~3.78) and blood pressure controls(OR: 2.13~2.30) were statistically significant predictors associated with participation in the program, based on the logistic regression analysis with GroupI and GroupIII. To increase participation in the health incentive point program, variables such as age, treatment compliance and blood pressure controls are more concerned. And, high-risk patients and family members need targeted health incentive programs.

• Nutrition Research and Practice
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• v.11 no.4
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• pp.327-333
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• 2017

BACKGROUND/OBJECTIVES: Complications of diabetes, such as cardiovascular disease, are associated with increased mortality among type 2 diabetes mellitus patients. Homocysteine has been recently identified as a predictor of cardiovascular disease-related complications in diabetes. We investigated whether or not supplementation with folic acid tablets can lower homocysteine levels and improve parameters related with vascular complications. SUBJECTS/METHODS: We conducted a non-randomized 8-week trial involving postmenopausal diabetic women (n = 25) supplemented with $800{\mu}g$ of folic acid ($400{\mu}g$ twice a day) daily. Subjects' serum levels of folate, homocysteine, and vitamin $B_{12}$ were measured, along with vascular function and brachial-ankle pulse wave velocity. RESULTS: Folic acid supplementation significantly increased serum folate levels (P < 0.0001), reduced homocysteine levels (P < 0.0001), and increased vitamin $B_{12}$ levels (P = 0.0063). There were significant decreases in low-density lipoprotein cholesterol levels as well as the ratios of low-density lipoprotein cholesterol to high-density lipoprotein cholesterol and total cholesterol to high-density lipoprotein cholesterol. Brachial-ankle pulse wave velocities were not altered by supplementation. Changes in serum vitamin $B_{12}$ after folic acid supplementation were negatively correlated with changes in brachial-ankle pulse wave velocity. CONCLUSIONS: In this study on postmenopausal Korean women with type 2 diabetes mellitus, folic acid supplementation reduced serum homocysteine levels, increased serum folate and vitamin $B_{12}$ levels, and lowered lipid parameters.

• Journal of the Korea Convergence Society
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• v.11 no.6
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• pp.401-410
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• 2020

The purpose of this study was to investigate predictors and mediating effects of physical activity and nourishment regulation on well-being among young and middle aged patients on DM medication and to compare between those with non-pharmacological treatment and those without. Data were obtained from 2017 community health survey including 1,480 DM patients with oral medication in the age between 20 and 49. Using SPSS 25.0 and AMOS 25.0, path analysis was performed to explore the association between personal factors (socio-economic status, health habit, eating habit and compliance of health examination) and well-being, along with mediating effects of physical activity. Results demonstrated the different mediating role of physical activity. In medication only group, there was no direct effect of physical activity and no indirect effect of personal factors. Direct effect of physical activity and indirect effects of predictors were found in those with non-pharmacological treatment group. When developing strategies to enhance well-being of young and middle aged diabetic patients, proper reflection of their age specific traits and disease management capability are essential.